Philippe Bidet

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. (2009)

Touchon, Marie, Hoede, Claire, Tenaillon, Olivier, Barbe, Valérie, Baeriswyl, Simon, Bidet, Philippe, ...

The Escherichia coli species represents one of the best-studied model organisms, but also encompasses a variety of commensal and pathogenic strains that diversify by high rates of genetic change. We...

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. (2009)

Touchon, Marie, Hoede, Claire, Tenaillon, Olivier, Barbe, Valérie, Baeriswyl, Simon, Bidet, Philippe, ...

The Escherichia coli species represents one of the best-studied model organisms, but also encompasses a variety of commensal and pathogenic strains that diversify by high rates of genetic change. We...

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. (2009)

Touchon, Marie, Hoede, Claire, Tenaillon, Olivier, Barbe, Valérie, Baeriswyl, Simon, Bidet, Philippe, ...

The Escherichia coli species represents one of the best-studied model organisms, but also encompasses a variety of commensal and pathogenic strains that diversify by high rates of genetic change. We...

Invasive group B streptococcal infections in infants, France. (2008)

Poyart, Claire, Réglier-Poupet, Hélène, Tazi, Asmaa, Billoët, Annick, Dmytruk, Nicolas, Bidet, Philippe, ...

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixty-four percent of the strains...

Invasive group B streptococcal infections in infants, France. (2008)

Poyart, Claire, Réglier-Poupet, Hélène, Tazi, Asmaa, Billoët, Annick, Dmytruk, Nicolas, Bidet, Philippe, ...

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixty-four percent of the strains...

Invasive Group B Streptococcal Infections in Infants, France (2008)

Claire Poyart, Hélène Réglier-Poupet, Asmaa Tazi, Annick Billoët, Nicolas Dmytruk, Philippe Bidet, ...

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixtyfour percent of the strains...

Invasive group B streptococcal infections in infants, France. (2008)

Poyart, Claire, Réglier-Poupet, Hélène, Tazi, Asmaa, Billoët, Annick, Dmytruk, Nicolas, Bidet, Philippe, ...

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixty-four percent of the strains...

Phylogenetic background and carriage of pathogenicity island-like domains in relation to antibiotic resistance profiles among Escherichia coli urosepsis isolates (2006)

Houdouin, Véronique, Bonacorsi, Stéphane, Bidet, Philippe, Bingen-Bidois, Martine, Barraud, Dominique, Bingen, Edouard

We studied 100 well-characterized E. coli blood isolates from patients with urosepsis for their susceptibility to nalidixic acid, ampicillin and trimethoprim–sulfamethoxazole, according to...

Phylogenetic background and carriage of pathogenicity island-like domains in relation to antibiotic resistance profiles among Escherichia coli urosepsis isolates (2006)

Houdouin, Véronique, Bonacorsi, Stéphane, Bidet, Philippe, Bingen-Bidois, Martine, Barraud, Dominique, Bingen, Edouard

We studied 100 well-characterized E. coli blood isolates from patients with urosepsis for their susceptibility to nalidixic acid, ampicillin and trimethoprim-sulfamethoxazole, according to prevalence...

Comparison of PCR-Ribotyping, Arbitrarily Primed PCR, and Pulsed-Field Gel Electrophoresis for Typing Clostridium difficile

Bidet, Philippe, Lalande, Valérie, Salauze, Béatrice, Burghoffer, Béatrice, Avesani, Véronique, Delmée, Michel, ...

Clostridium difficile is now recognized as the major agent responsible for nosocomial diarrhea in adults. Among the genotyping methods available, arbitrarily primed PCR (AP-PCR), PCR-ribotyping, and...

Ralstonia paucula (Formerly CDC Group IV c-2): Unsuccessful Strain Differentiation with PCR-Based Methods, Study of the 16S-23S Spacer of the rRNA Operon, and Comparison with Other Ralstonia Species (R. eutropha, R. pickettii, R. gilardii, and R. solanacearum)

Moissenet, Didier, Bidet, Philippe, Garbarg-Chenon, Antoine, Arlet, Guillaume, Vu-Thien, Hoang

Ralstonia paucula (formerly CDC group IV c-2) can cause serious human infections. Confronted in 1995 with five cases of nosocomial bacteremia, we found that pulsed-field gel electrophoresis could not...

Clonal Relationship between U.S. and French Serotype V Group B Streptococcus Isolates

Fitoussi, Frederic, Mariani-Kurkdjian, Patricia, Raymond, Josette, Brahimi, Naima, Bidet, Philippe, ...

We examined the genetic diversity of serotype V group B streptococcus (GBS) isolates in the Paris area and compared them with the predominant American serotype V clone. Pulsed-field gel...

Activity of Telithromycin against Penicillin-Resistant Streptococcus pneumoniae Isolates Recovered from French Children with Invasive and Noninvasive Infections

Bingen, Edouard, Doit, Catherine, Loukil, Chawki, Brahimi, Naima, Bidet, Philippe, Deforche, Dominique, ...

We compared the activities of telithromycin, erythromycin, azithromycin, josamycin, penicillin G, amoxicillin, cefpodoxime, and ceftriaxone against invasive and noninvasive non-penicillin-susceptible...

Telithromycin Susceptibility and Genomic Diversity of Macrolide-Resistant Serotype III Group B Streptococci Isolated in Perinatal Infections

Bingen, Edouard, Doit, Catherine, Bidet, Philippe, Brahimi, Naima, Deforche, Dominique

We studied the telithromycin, erythromycin, azithromycin, and clindamycin susceptibilities of serotype III macrolide-resistant group B streptococci, together with genetic mechanisms of resistance and...

The Siderophore Receptor IroN, but Not the High-Pathogenicity Island or the Hemin Receptor ChuA, Contributes to the Bacteremic Step of Escherichia coli Neonatal Meningitis

Nègre, Valérie Lefranc, Bonacorsi, Stéphane, Schubert, Soren, Bidet, Philippe, Nassif, Xavier, Bingen, Edouard

Using a neonatal rat meningitis model, we examined the involvement of three iron uptake systems, namely, the high-pathogenicity island, the hemin receptor ChuA, and the siderophore receptor IroN, in...

Emergence of Macrolide-Resistant Streptococcus pyogenes Strains in French Children

Bingen, Edouard, Bidet, Philippe, Mihaila-Amrouche, Liliana, Doit, Catherine, Forcet, Samuel, Brahimi, Naïma, ...

We studied the antimicrobial susceptibility of 322 Streptococcus pyogenes throat isolates from French children and their serotype and genomic diversity. A total of 22.4% were erythromycin resistant,...

Species Distribution and Ribotype Diversity of Burkholderia cepacia Complex Isolates from French Patients with Cystic Fibrosis

Brisse, Sylvain, Cordevant, Christophe, Vandamme, Peter, Bidet, Philippe, Loukil, Chawki, Chabanon, Gérard, ...

A total of 153 Burkholderia cepacia strains obtained from 153 French patients with cystic fibrosis were identified as Burkholderia multivorans (51.6%) or Burkholderia cenocepacia (45.1%). Eighty-two...

In Vivo Transfer of Plasmid-Encoded ACC-1 AmpC from Klebsiella pneumoniae to Escherichia coli in an Infant and Selection of Impermeability to Imipenem in K. pneumoniae

Bidet, Philippe, Burghoffer, Béatrice, Gautier, Valérie, Brahimi, Naïma, Mariani-Kurkdjian, Patricia, El-Ghoneimi, Alaa, ...

We describe in vivo selection of a Klebsiella pneumoniae strain with diminished imipenem susceptibility attributable to plasmid-encoded ACC-1 β-lactamase production and loss of a 36-kDa major outer...

Multiple Insertional Events, Restricted by the Genetic Background, Have Led to Acquisition of Pathogenicity Island IIJ96-Like Domains among Escherichia coli Strains of Different Clinical Origins

Bidet, Philippe, Bonacorsi, Stéphane, Clermont, Olivier, De Montille, Caroline, Brahimi, Naima, Bingen, Edouard

We investigated the dissemination of pathogenicity island (PAI) IIJ96-like elements (hra, hly, cnf1, and pap) among 455 Escherichia coli isolates from children and adults with urinary tract infection...

Comparison of PCR-Ribotyping, Arbitrarily Primed PCR, and Pulsed-Field Gel Electrophoresis for Typing Clostridium difficile

Bidet, Philippe, Lalande, Valérie, Salauze, Béatrice, Burghoffer, Béatrice, Avesani, Véronique, Delmée, Michel, ...

Clostridium difficile is now recognized as the major agent responsible for nosocomial diarrhea in adults. Among the genotyping methods available, arbitrarily primed PCR (AP-PCR), PCR-ribotyping, and...

Ralstonia paucula (Formerly CDC Group IV c-2): Unsuccessful Strain Differentiation with PCR-Based Methods, Study of the 16S-23S Spacer of the rRNA Operon, and Comparison with Other Ralstonia Species (R. eutropha, R. pickettii, R. gilardii, and R. solanacearum)

Moissenet, Didier, Bidet, Philippe, Garbarg-Chenon, Antoine, Arlet, Guillaume, Vu-Thien, Hoang

Ralstonia paucula (formerly CDC group IV c-2) can cause serious human infections. Confronted in 1995 with five cases of nosocomial bacteremia, we found that pulsed-field gel electrophoresis could not...

Clonal Relationship between U.S. and French Serotype V Group B Streptococcus Isolates

Fitoussi, Frederic, Mariani-Kurkdjian, Patricia, Raymond, Josette, Brahimi, Naima, Bidet, Philippe, ...

We examined the genetic diversity of serotype V group B streptococcus (GBS) isolates in the Paris area and compared them with the predominant American serotype V clone. Pulsed-field gel...

Activity of Telithromycin against Penicillin-Resistant Streptococcus pneumoniae Isolates Recovered from French Children with Invasive and Noninvasive Infections

Bingen, Edouard, Doit, Catherine, Loukil, Chawki, Brahimi, Naima, Bidet, Philippe, Deforche, Dominique, ...

We compared the activities of telithromycin, erythromycin, azithromycin, josamycin, penicillin G, amoxicillin, cefpodoxime, and ceftriaxone against invasive and noninvasive non-penicillin-susceptible...

Telithromycin Susceptibility and Genomic Diversity of Macrolide-Resistant Serotype III Group B Streptococci Isolated in Perinatal Infections

Bingen, Edouard, Doit, Catherine, Bidet, Philippe, Brahimi, Naima, Deforche, Dominique

We studied the telithromycin, erythromycin, azithromycin, and clindamycin susceptibilities of serotype III macrolide-resistant group B streptococci, together with genetic mechanisms of resistance and...

The Siderophore Receptor IroN, but Not the High-Pathogenicity Island or the Hemin Receptor ChuA, Contributes to the Bacteremic Step of Escherichia coli Neonatal Meningitis

Nègre, Valérie Lefranc, Bonacorsi, Stéphane, Schubert, Soren, Bidet, Philippe, Nassif, Xavier, Bingen, Edouard

Using a neonatal rat meningitis model, we examined the involvement of three iron uptake systems, namely, the high-pathogenicity island, the hemin receptor ChuA, and the siderophore receptor IroN, in...

Emergence of Macrolide-Resistant Streptococcus pyogenes Strains in French Children

Bingen, Edouard, Bidet, Philippe, Mihaila-Amrouche, Liliana, Doit, Catherine, Forcet, Samuel, Brahimi, Naïma, ...

We studied the antimicrobial susceptibility of 322 Streptococcus pyogenes throat isolates from French children and their serotype and genomic diversity. A total of 22.4% were erythromycin resistant,...

Species Distribution and Ribotype Diversity of Burkholderia cepacia Complex Isolates from French Patients with Cystic Fibrosis

Brisse, Sylvain, Cordevant, Christophe, Vandamme, Peter, Bidet, Philippe, Loukil, Chawki, Chabanon, Gérard, ...

A total of 153 Burkholderia cepacia strains obtained from 153 French patients with cystic fibrosis were identified as Burkholderia multivorans (51.6%) or Burkholderia cenocepacia (45.1%). Eighty-two...

Multiple Insertional Events, Restricted by the Genetic Background, Have Led to Acquisition of Pathogenicity Island IIJ96-Like Domains among Escherichia coli Strains of Different Clinical Origins

Bidet, Philippe, Bonacorsi, Stéphane, Clermont, Olivier, De Montille, Caroline, Brahimi, Naima, Bingen, Edouard

We investigated the dissemination of pathogenicity island (PAI) IIJ96-like elements (hra, hly, cnf1, and pap) among 455 Escherichia coli isolates from children and adults with urinary tract infection...

In Vivo Transfer of Plasmid-Encoded ACC-1 AmpC from Klebsiella pneumoniae to Escherichia coli in an Infant and Selection of Impermeability to Imipenem in K. pneumoniae

Bidet, Philippe, Burghoffer, Béatrice, Gautier, Valérie, Brahimi, Naïma, Mariani-Kurkdjian, Patricia, El-Ghoneimi, Alaa, ...

We describe in vivo selection of a Klebsiella pneumoniae strain with diminished imipenem susceptibility attributable to plasmid-encoded ACC-1 β-lactamase production and loss of a 36-kDa major outer...

Treatment Failure of Nosocomial Pertussis Infection in a Very-Low-Birth-Weight Neonate

Bonacorsi, Stéphane, Farnoux, Caroline, Bidet, Philippe, Caro, Valérie, Aizenfisz, Sophie, Benhayoun, Mounir, ...

We describe a case of nosocomial maternal transmission of Bordetella pertussis to a very-low-birth-weight (VLBW) neonate in whom treatment was unsuccessful. This case underscores the need for rapid...

First Detection of the Ambler Class C 1 AmpC β-Lactamase in Citrobacter freundii by a New, Simple Double-Disk Synergy Test▿

Ruppé, Etienne, Bidet, Philippe, Verdet, Charlotte, Arlet, Guillaume, Bingen, Edouard

We report on the first detection of an AmpC-type Ambler class C 1 (ACC-1) β-lactamase in Citrobacter freundi isolated from a patient also harboring ACC-1-producing Escherichia coli and Klebsiella...

Detection and Identification by PCR of a Highly Virulent Phylogenetic Subgroup among Extraintestinal Pathogenic Escherichia coli B2 Strains▿

Bidet, Philippe, Metais, Arnaud, Mahjoub-Messai, Farah, Durand, Lionel, Dehem, Marie, Aujard, Yannick, ...

Closely related Escherichia coli B2 strains O1:K1, O2:K1, O18:K1, and O45:K1 constitute a major subgroup causing extraintestinal infections. A DNA pathoarray analysis was used to develop a PCR...

Molecular Epidemiology of the sil Streptococcal Invasive Locus in Group A Streptococci Causing Invasive Infections in French Children▿

Bidet, Philippe, Courroux, Céline, Salgueiro, Christophe, Carol, Agnès, Mariani-Kurkdjian, Patricia, Bonacorsi, Stéphane, ...

We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6...

A New O-Antigen Gene Cluster Has a Key Role in the Virulence of the Escherichia coli Meningitis Clone O45:K1:H7▿

Plainvert, Céline, Bidet, Philippe, Peigne, Chantal, Barbe, Valérie, Médigue, Claudine, Denamur, Erick, ...

A new highly pathogenic clone of Escherichia coli meningitis strains harboring the unusual serogroup O45 has recently emerged in France. To gain insight into the pathogenicity of this new clone, we...

Invasive Group B Streptococcal Infections in Infants, France

Poyart, Claire, Réglier-Poupet, Hélène, Tazi, Asmaa, Billoët, Annick, Dmytruk, Nicolas, Bidet, Philippe, ...

Clinical features and molecular characterization of 109 group B streptococci causing neonatal invasive infections were determined over an 18-month period in France. Sixty-four percent of the strains...

Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths

Touchon, Marie, Hoede, Claire, Tenaillon, Olivier, Barbe, Valérie, Baeriswyl, Simon, Bidet, Philippe, ...

The Escherichia coli species represents one of the best-studied model organisms, but also encompasses a variety of commensal and pathogenic strains that diversify by high rates of genetic change. We...

Real-Time PCR Measurement of Persistence of Bordetella pertussis DNA in Nasopharyngeal Secretions during Antibiotic Treatment of Young Children with Pertussis ▿

Bidet, Philippe, Liguori, Sandrine, De Lauzanne, Agathe, Caro, Valérie, Lorrot, Mathie, Carol, Agnès, ...

We used real-time PCR to examine the persistence of Bordetella pertussis DNA in serial nasopharyngeal aspirates from 22 children treated for pertussis. After 5 days of treatment, PCR was positive for...

Population Snapshot of Streptococcus pneumoniae Serotype 19A Isolates before and after Introduction of Seven-Valent Pneumococcal Vaccination for French Children▿

Mahjoub-Messai, Farah, Doit, Catherine, Koeck, Jean-Louis, Billard, Typhaine, Evrard, Bénédicte, Bidet, Philippe, ...

Serotype 19A Streptococcus pneumoniae strains are now more frequent in French children than before the introduction of a seven-valent conjugate vaccine (PCV7). By applying multilocus sequence typing...