Coisy-Quivy, Marjorie, Touzet, Olivia, Bourret, Annick, Hipskind, Robert, Mercier, Jacques, Fort, Philippe, ...
The contractile activity of striated muscle depends on myofibrils that are highly ordered macromolecular complexes. The protein components of myofibrils are well characterized, but it remains largely...
Coisy-Quivy, Marjorie, Touzet, Olivia, Bourret, Annick, Hipskind, Robert, Mercier, Jacques, Fort, Philippe, ...
The contractile activity of striated muscle depends on myofibrils that are highly ordered macromolecular complexes. The protein components of myofibrils are well characterized, but it remains largely...
Coisy-Quivy, Marjorie, Touzet, Olivia, Bourret, Annick, Hipskind, Robert, Mercier, Jacques, Fort, Philippe, ...
The contractile activity of striated muscle depends on myofibrils that are highly ordered macromolecular complexes. The protein components of myofibrils are well characterized, but it remains largely...
Evolution of the Rho family of ras-like GTPases in eukaryotes. (2007)
Boureux, Anthony, Vignal, Emmanuel, Faure, Sandrine, Fort, Philippe
GTPases of the Rho family are molecular switches that play important roles in converting and amplifying external signals into cellular effects. Originally demonstrated to control the dynamics of the...
Evolution of the Rho family of ras-like GTPases in eukaryotes. (2007)
Boureux, Anthony, Vignal, Emmanuel, Faure, Sandrine, Fort, Philippe
GTPases of the Rho family are molecular switches that play important roles in converting and amplifying external signals into cellular effects. Originally demonstrated to control the dynamics of the...
Evolution of the Rho Family of Ras-Like GTPases in Eukaryotes (2007)
Boureux, Anthony, Vignal, Emmanuel, Faure, Sandrine, Fort, Philippe
GTPases of the Rho family are molecular switches that play important roles in converting and amplifying external signals into cellular effects. Originally demonstrated to control the dynamics of the...
Brazier, Helene, Stephens, Sebastien Robert, Ory, Stephane, Fort, Philippe, Morrison, Nigel Alexander, Blangy, Anne
Yes
Brazier, Helene, Stephens, Sebastien Robert, Ory, Stephane, Fort, Philippe, Morrison, Nigel Alexander, Blangy, Anne, ...
Yes
Identification of TRIO-GEFD1 chemical inhibitors using the yeast exchange assay. (2006)
Blangy, Anne, Bouquier, Nathalie, Gauthier-Rouvière, Cécile, Schmidt, Susanne, Debant, Anne, Leonetti, Jean-Paul, ...
BACKGROUND INFORMATION: Rho GTPases are involved in many biological processes and participate in cancer development. Their activation is catalysed by exchange factors [RhoGEFs (Rho GTPase guanine...
Brazier, Hélène, Stephens, Sébastien, Ory, Stéphane, Fort, Philippe, Morrison, Nigel, Blangy, Anne
RhoGTPases regulate actin cytoskeleton dynamics, a key element in osteoclast biology. We identified three novel genes induced during RANKL-stimulated osteoclastogenesis among RhoGTPases and their...
Identification of TRIO-GEFD1 chemical inhibitors using the yeast exchange assay. (2006)
Blangy, Anne, Bouquier, Nathalie, Gauthier-Rouvière, Cécile, Schmidt, Susanne, Debant, Anne, Leonetti, Jean-Paul, ...
BACKGROUND INFORMATION: Rho GTPases are involved in many biological processes and participate in cancer development. Their activation is catalysed by exchange factors [RhoGEFs (Rho GTPase guanine...
Brazier, Hélène, Stephens, Sébastien, Ory, Stéphane, Fort, Philippe, Morrison, Nigel, Blangy, Anne
RhoGTPases regulate actin cytoskeleton dynamics, a key element in osteoclast biology. We identified three novel genes induced during RANKL-stimulated osteoclastogenesis among RhoGTPases and their...
Brazier, Helene, Stephens, Sebastien Robert, Ory, Stephane, Fort, Philippe, Morrison, Nigel Alexander, Blangy, Anne
Brazier, Helene, Stephens, Sebastien Robert, Ory, Stephane, Fort, Philippe, Morrison, Nigel Alexander, Blangy, Anne
Evolution of the Rho Family of Ras-like GTPases in Eukaryotes (2006)
Boureux, Anthony, Vignal, Emmanuel, Faure, Sandrine, Fort, Philippe
GTPases of the Rho family are molecular switches that play important roles in converting and amplifying external signals into cellular effects. Originally demonstrated to control the dynamics of the...
Fort, Philippe, Rech, Jocelyne, Vie, Annick, Piechaczyk, Marc, Bonnieu, Anne, Jeanteur, Philippe, ...
Rapid and transient activation of both c-fos transcription and mRNA accumulation occurs when resting CCL39 hamster fibroblasts are serum-stimulated to grow. By using several combinations of serum and...
Meriane, Mayya, Roux, Pierre, Primig, Michael, Fort, Philippe, Gauthier-Rouvière, Cécile
The Rho family of GTP-binding proteins plays a critical role in a variety of cellular processes, including cytoskeletal reorganization and activation of kinases such as p38 and C-jun N-terminal...
RhoG GTPase Controls a Pathway That Independently Activates Rac1 and Cdc42Hs
Gauthier-Rouvière, Cécile, Vignal, Emmanuel, Mériane, Mayya, Roux, Pierre, Montcourier, Philippe, Fort, Philippe
RhoG is a member of the Rho family of GTPases that shares 72% and 62% sequence identity with Rac1 and Cdc42Hs, respectively. We have expressed mutant RhoG proteins fused to the green fluorescent...
Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt
Zugasti, Olivier, Rul, Wilfrid, Roux, Pierre, Peyssonnaux, Carole, Eychene, Alain, Franke, Thomas F., ...
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in...
The GTP/GDP Cycling of Rho GTPase TCL Is an Essential Regulator of the Early Endocytic Pathway
De Toledo, Marion, Senic-Matuglia, Francesca, Salamero, Jean, Uze, Gilles, Comunale, Franck, Fort, Philippe, ...
Rho GTPases are key regulators of actin dynamics. We report that the Rho GTPase TCL, which is closely related to Cdc42 and TC10, localizes to the plasma membrane and the early/sorting endosomes in...
Meriane, Mayya, Roux, Pierre, Primig, Michael, Fort, Philippe, Gauthier-Rouvière, Cécile
The Rho family of GTP-binding proteins plays a critical role in a variety of cellular processes, including cytoskeletal reorganization and activation of kinases such as p38 and C-jun N-terminal...
RhoG GTPase Controls a Pathway That Independently Activates Rac1 and Cdc42Hs
Gauthier-Rouvière, Cécile, Vignal, Emmanuel, Mériane, Mayya, Roux, Pierre, Montcourier, Philippe, Fort, Philippe
RhoG is a member of the Rho family of GTPases that shares 72% and 62% sequence identity with Rac1 and Cdc42Hs, respectively. We have expressed mutant RhoG proteins fused to the green fluorescent...
Raf-MEK-Erk Cascade in Anoikis Is Controlled by Rac1 and Cdc42 via Akt
Zugasti, Olivier, Rul, Wilfrid, Roux, Pierre, Peyssonnaux, Carole, Eychene, Alain, Franke, Thomas F., ...
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in...
The GTP/GDP Cycling of Rho GTPase TCL Is an Essential Regulator of the Early Endocytic Pathway
De Toledo, Marion, Senic-Matuglia, Francesca, Salamero, Jean, Uze, Gilles, Comunale, Franck, Fort, Philippe, ...
Rho GTPases are key regulators of actin dynamics. We report that the Rho GTPase TCL, which is closely related to Cdc42 and TC10, localizes to the plasma membrane and the early/sorting endosomes in...
Weill, Mylène, Fort, Philippe, Berthomieu, Arnaud, Dubois, Marie Pierre, Pasteur, Nicole, Raymond, Michel
Acetylcholinesterase (AChE) is the target of two major insecticide families, organophosphates (OPs) and carbamates. AChE insensitivity is a frequent resistance mechanism in insects and responsible...
Duron, Olivier, Boureux, Anthony, Echaubard, Pierre, Berthomieu, Arnaud, Berticat, Claire, Fort, Philippe, ...
Wolbachia strains are maternally inherited endosymbiotic bacteria that infect many arthropod species and have evolved several different ways of manipulating their hosts, the most frequent way being...
Duron, Olivier, Fort, Philippe, Weill, Mylène
Wolbachia are maternally inherited endosymbiotic bacteria that infect many arthropod species and may induce cytoplasmic incompatibility (CI) resulting in abortive embryonic development. Among all the...
A Presumptive Developmental Role for a Sea Urchin Cyclin B Splice Variant
Lozano, Jean-Claude, Schatt, Philippe, Marquès, François, Peaucellier, Gérard, Fort, Philippe, Féral, Jean-Pierre, ...
We show that a splice variant–derived cyclin B is produced in sea urchin oocytes and embryos. This splice variant protein lacks highly conserved sequences in the COOH terminus of the protein. It is...