Philippe I. H. Bastiaens

Ezrin is a downstream effector of trafficking PKC–integrin complexes involved in the control of cell motility

Ng, Tony, Parsons, Maddy, Hughes, William E., Monypenny, James, Zicha, Daniel, Gautreau, Alexis, ...

Protein kinase C (PKC) α has been implicated in β1 integrin-mediated cell migration. Stable expression of PKCα is shown here to enhance wound closure. This PKC-driven migratory response directly...

Ezrin is a downstream effector of trafficking PKC–integrin complexes involved in the control of cell motility

Ng, Tony, Parsons, Maddy, Hughes, William E., Monypenny, James, Zicha, Daniel, Gautreau, Alexis, ...

Protein kinase C (PKC) α has been implicated in β1 integrin-mediated cell migration. Stable expression of PKCα is shown here to enhance wound closure. This PKC-driven migratory response directly...

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin

Xouri, Georgia, Squire, Anthony, Dimaki, Maria, Geverts, Bart, Verveer, Peter J, Taraviras, Stavros, ...

To maintain genome integrity, eukaryotic cells initiate DNA replication once per cell cycle after assembling prereplicative complexes (preRCs) on chromatin at the end of mitosis and during G1. In S...

Recruitment of Eph receptors into signaling clusters does not require ephrin contact

Wimmer-Kleikamp, Sabine H., Janes, Peter W., Squire, Anthony, Bastiaens, Philippe I.H., Lackmann, Martin

Eph receptors and their cell membrane–bound ephrin ligands regulate cell positioning and thereby establish or stabilize patterns of cellular organization. Although it is recognized that ephrin...