Philippe Krebs

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery (2009)

Michael J. Barnes, Philippe Krebs, Nathaniel Harris, Celine Eidenschenk, Rosana Gonzalez-Quintial, Carrie N. Arnold, ...

Regulatory T (Treg) cells expressing forkhead box P3 (Foxp3) arise during thymic selection among thymocytes with modestly self-reactive T cell receptors. In vitro studies suggest Foxp3 can also be...

Immunopathological Basis of Virus-induced Myocarditis (2004)

Reinhard Maier, Philippe Krebs, Burkhard Ludewig

Heart diseases are an important cause of morbidity and mortality in industrialized countries. Dilated cardiomyopathy (DCM), one of the most common heart diseases, may be the consequence of...

Immunopathological Basis of Virus-induced Myocarditis (2004)

Reinhard Maier, Philippe Krebs, Burkhard Ludewig

Heart diseases are an important cause of morbidity and mortality in industrialized countries. Dilated cardiomyopathy (DCM), one of the most common heart diseases, may be the consequence of...

Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8+-T-Lymphocyte Responses

Bocharov, Gennady, Ludewig, Burkhard, Bertoletti, Antonio, Klenerman, Paul, Junt, Tobias, Krebs, Philippe, ...

The speed of virus replication has typically been seen as an advantage for a virus in overcoming the ability of the immune system to control its population growth. Under some circumstances, the...

Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8+-T-Lymphocyte Responses

Bocharov, Gennady, Ludewig, Burkhard, Bertoletti, Antonio, Klenerman, Paul, Junt, Tobias, Krebs, Philippe, ...

The speed of virus replication has typically been seen as an advantage for a virus in overcoming the ability of the immune system to control its population growth. Under some circumstances, the...

Molecular Characterization of Virus-induced Autoantibody Responses

Ludewig, Burkhard, Krebs, Philippe, Metters, Helen, Tatzel, Jutta, Türeci, Özlem, Sahin, Ugur

Here we present a comprehensive molecular mapping of virus-induced autoimmune B cell responses obtained by serological identification of antigens by recombinant expression cloning analysis....

Immunopathological Basis of Virus-induced Myocarditis

Maier, Reinhard, Krebs, Philippe, Ludewig, Burkhard

Heart diseases are an important cause of morbidity and mortality in industrialized countries. Dilated cardiomyopathy (DCM), one of the most common heart diseases, may be the consequence of...

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery

Barnes, Michael J, Krebs, Philippe, Harris, Nathaniel, Eidenschenk, Celine, Gonzalez-Quintial, Rosana, Arnold, Carrie N, ...

Regulatory T (Treg) cells expressing forkhead box P3 (Foxp3) arise during thymic selection among thymocytes with modestly self-reactive T cell receptors. In vitro studies suggest Foxp3 can also be...

Immunopathological Basis of Lymphocytic Choriomeningitis Virus-Induced Chorioretinitis and Keratitis▿

Zinkernagel, Martin S., Bolinger, Beatrice, Krebs, Philippe, Onder, Lucas, Miller, Simone, Ludewig, Burkhard

The infection of humans with the rodent-borne lymphocytic choriomeningitis virus (LCMV) can lead to central nervous system disease in adults or severe neurological disease with hydrocephalus and...

Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function

Blasius, Amanda L., Brandl, Katharina, Crozat, Karine, Xia, Yu, Khovananth, Kevin, Krebs, Philippe, ...

The classical recessive coat color mutation misty (m) arose spontaneously on the DBA/J background and causes generalized hypopigmentation and localized white-spotting in mice, with a lack of pigment...