Soulard, Valérie, Roland, Jacques, Gorgette, Olivier, Barbier, Eliane, Cazenave, Pierre-André, Pied, Sylviane
Abstract Background In murine models of malaria, an early proinflammatory response has been associated with the resolution of blood-stage infection. To dissect the protective immune mechanims that...
Duarte, Joana, Deshpande, Prakash, Guiyedi, Vincent, Mécheri, Salah, Fesel, Constantin, Cazenave, Pierre-André, ...
Abstract Background There is an increase of serum levels of IgE during Plasmodium falciparum infections in individuals living in endemic areas. These IgEs either protect against malaria or increase...
Hachemi-Rachedi, Soulef, Drapier, Anne-Marie, Cazenave, Pierre-André, Sanchez, Pierre
Using an `oligoclonal' model, we have previously shown that mice transgenic for a μ chain (H3) and deficient for κ chain expression display a mature B cell repertoire largely dominated by the...
Boubou, Mariama Idrissa, Collette, Alexis, Voegtlé, Danielle, Mazier, Dominique, Cazenave, Pierre-André, Pied, Sylviane
To characterize the T cells involved in the pathogenesis of cerebral malaria (CM) induced by infection with Plasmodium berghei ANKA clone 1.49L (PbA 1.49L), the occurrence of the disease was assessed...
Nadel, Bertrand, Drapier, Anne-Marie, Andrade, Lulz, Cazenave, Pierre-André, Sanchez, Pierre
To gain insights into the composition of the B cell repertoire, we have investigated VH gene family expression associated with individual light chains. For this purpose, we have examined the use of...
Ly-49 antigen defines an {alpha}{beta} TCR population in i-IEL with an extrathymic maturation (1992)
Roland, Jacques, Cazenave, Pierre-André
In this paper we describe a monoclonal antibody, JR9–318, which was obtained from a wild-derived mouse immunized with the M14T cell line (CD3+CD4−CD8−) in order to describe antigenic...
Rueff-Juy, Dominique, Liberman, Isabelle, Drapier, Anne-Marie, Guillon, Jean-Claude, Leclerc, Claude, Cazenave, Pierre-André, ...
We have analysed the mechanisms underlying the differences In the susceptibilities of adult and newborn mice to the pathogenic effects of antl-CD3 mAbs. Our data show that the thymus cell number in...
Bernabé, Rosa R., Coutinho, Antonio, Martínez-Alonso, Carlos, Cazenave, Pierre-André
El copyright pertenece a The Rockefeller University Press
Identification of two cerebral malaria resistance loci using an inbred wild-derived mouse strain
Bagot, Sébastien, Campino, Susana, Penha-Gonçalves, Carlos, Pied, Sylviane, Cazenave, Pierre-André, Holmberg, Dan
Malaria is a complex infectious disease in which the host/parasite interaction is strongly influenced by host genetic factors. The consequences of plasmodial infections range from asymptomatic to...
Gorgette, Olivier, Existe, Alexandre, Boubou, Mariama Idrissa, Bagot, Sébastien, Guénet, Jean-Louis, Mazier, Dominique, ...
Plasmodium berghei ANKA induces a fatal neurological syndrome known as cerebral malaria (CM) in susceptible mice. Host genetic elements are among the key factors determining susceptibility or...
Bagot, Sébastien, Nogueira, Fatima, Collette, Alexis, Do Rosario, Virgilio, Lemonier, François, Cazenave, Pierre-André, ...
To obtain insight into the mechanisms that contribute to the pathogenesis of Plasmodium infections, we developed an improved rodent model that mimics human malaria closely by inducing cerebral...
Babay, Besma E. C., Louzir, Hechmi, Kebaïer, Chahnaz, Boubaker, Samir, Dellagi, Koussay, Cazenave, Pierre-André
Two inbred mouse strains, derived from feral founders, are susceptible to experimental leishmaniasis due to Leishmania major and support a disease of a severity intermediate between those observed in...
Identification of two cerebral malaria resistance loci using an inbred wild-derived mouse strain
Bagot, Sébastien, Campino, Susana, Penha-Gonçalves, Carlos, Pied, Sylviane, Cazenave, Pierre-André, Holmberg, Dan
Malaria is a complex infectious disease in which the host/parasite interaction is strongly influenced by host genetic factors. The consequences of plasmodial infections range from asymptomatic to...
Gorgette, Olivier, Existe, Alexandre, Boubou, Mariama Idrissa, Bagot, Sébastien, Guénet, Jean-Louis, Mazier, Dominique, ...
Plasmodium berghei ANKA induces a fatal neurological syndrome known as cerebral malaria (CM) in susceptible mice. Host genetic elements are among the key factors determining susceptibility or...
Bagot, Sébastien, Nogueira, Fatima, Collette, Alexis, Do Rosario, Virgilio, Lemonier, François, Cazenave, Pierre-André, ...
To obtain insight into the mechanisms that contribute to the pathogenesis of Plasmodium infections, we developed an improved rodent model that mimics human malaria closely by inducing cerebral...
Babay, Besma E. C., Louzir, Hechmi, Kebaïer, Chahnaz, Boubaker, Samir, Dellagi, Koussay, Cazenave, Pierre-André
Two inbred mouse strains, derived from feral founders, are susceptible to experimental leishmaniasis due to Leishmania major and support a disease of a severity intermediate between those observed in...
Duarte, Joana, Deshpande, Prakash, Guiyedi, Vincent, Mécheri, Salah, Fesel, Constantin, Cazenave, Pierre-André, ...
Guiyedi, Vincent, Chanseaud, Youri, Fesel, Constantin, Snounou, Georges, Rousselle, Jean-Claude, Lim, Pharat, ...
Soulard, Valérie, Roland, Jacques, Sellier, Christèle, Gruner, Anne Charlotte, Franetich, Jean-François, ...
NKT cells are a population of innate-like lymphocytes that display effector functions and immunoregulatory properties. We characterized the NKT cell response induced in C57BL/6 mice during a primary...
Constitutive Endocytosis and Degradation of the Pre-T Cell Receptor
Panigada, Maddalena, Porcellini, Simona, Barbier, Eliane, Hoeflinger, Sonja, Cazenave, Pierre-André, Gu, Hua, ...
The pre-T cell receptor (TCR) signals constitutively in the absence of putative ligands on thymic stroma and signal transduction correlates with translocation of the pre-TCR into glycolipid-enriched...