Pierre Drion

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice (2009)

Bedoret, Denis, Wallemacq, Hugues, Marichal, Thomas, Desmet, Christophe, Quesada Calvo, Florence, Henry, E, ...

The respiratory tract is continuously exposed to both innocuous airborne antigens and immunostimulatory molecules of microbial origin, such as LPS. At low concentrations, airborne LPS can induce a...

Cloning of the koi herpesvirus genome as an infectious bacterial artificial chromosome demonstrates that disruption of the thymidine kinase locus induces partial attenuation in Cyprinus carpio koi. (2008)

Costes, Bérénice, Fournier, Guillaume, Michel, Benjamin, Delforge, Cédric, Stalin Raj, V, Dewals, Benjamin G, ...

Koi herpesvirus (KHV) is the causative agent of a lethal disease in koi and common carp. In the present study, we describe the cloning of the KHV genome as a stable and infectious bacterial...

Malignant catarrhal fever induced by alcelaphine herpesvirus 1 is associated with proliferation of CD8+ T cells supporting a latent infection. (2008)

Dewals, Benjamin G, Boudry, Christel, Farnir, Frédéric, Drion, Pierre, Vanderplasschen, Alain

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the...

Evolution of anti-eCG antibodies in response to eCG doses and number of injections. Relation with rabbit does productivity (2008)

Theau-Clément, M, Lebas, F, Beckers, JF, Drion, Pierre

The aim of this experiment was to study the kinetics of anti-eCG (equine chorionic gonadotrophin) antibodies in relation to eCG dose (8 or 25 IU) and number of injections (n = 11) in comparison with...

Influence of the Ixodes ricinus tick blood-feeding on the antigen-specific antibody response in vivo. (2008)

Menten-Dedoyart, Catherine, Couvreur, B, Thellin, Olivier, Drion, Pierre, Herry, M, Jolois, Olivier, ...

The blood meal of hard ticks such as Ixodes ricinus lasts several days. This is made possible by tick salivary factors that inhibit inflammation, haemostasis and the host immune response. We assessed...

In vivo administration of a PKA type I inhibitor (Rp-8-Br-cAMPS) restores T-cell responses in retrovirus-infected mice (2008)

Nayjib, B, Zeddou, Mustapha, Drion, Pierre, Boniver, Jacques, Tasken, K, Rahmouni, Souad, ...

Murine AIDS (MAIDS) is caused by infection with the murine leukemia retrovirus RadLV-Rs and is characterized by T-cell anergy and severe immunodeficiency with increased susceptibilty to several...

Cloning of Koi Herpesvirus Genome as an Infectious Bacterial Artificial Chromosome: Demonstration That Disruption of the Tk Locus Induces a Partial Attenuation in Cyprinus Carpio Koi (2008)

Costes, Bérénice, Fournier, Guillaume, Michel, Benjamin, Delforge, Cécile, Raj, V S, Dewals, Benjamin J, ...

Koi herpesvirus (KHV) is the causative agent of a lethal disease in koi and common carp. In the present study, we described the cloning of the KHV genome as a stable and infectious BAC clone that can...

The A5 gene of alcelaphine herpesvirus 1 encodes a constitutively active G-protei n-coupled receptor that is non-essential for the induction of malignant catarrhal fever in rabbits (2007)

Boudry, Christel, Markine-Goriaynoff, N, Delforge, C, Springael, JY, De Leval, Laurence, Drion, Pierre, ...

Many gammaherpesviruses encode G-protein-coupled receptors (GPCRs). Several in vivo studies have revealed that gammaherpesvirus GPCRs are important for viral replication and for virus-induced...

Natural antibody--complement dependent neutralization of bovine herpesvirus 4 by human serum (2007)

Machiels, Bénédicte, Gillet, Laurent, Brito, Sieberth Do Nascimento, Drion, Pierre, Delforge, Cédric, Nizet, Yannick, ...

In contrast to most gammaherpesviruses, Bovine herpesvirus 4 (BoHV-4) has a broad range of host species both in vitro and in vivo. Several in vitro studies demonstrated that some human cell lines are...

Natural Antibody--Complement Dependent Neutralization of Bovine Herpesvirus 4 by Human Serum (2007)

Machiels, Bénédicte, Gillet, Louis, Nascimento Brito, S D, Drion, Pierre, Delforge, Cécile, Nizet, Y, ...

In contrast to most gammaherpesviruses, Bovine herpesvirus 4 (BoHV-4) has a broad range of host species both in vitro and in vivo. Several in vitro studies demonstrated that some human cell lines are...

The A5 gene of alcelaphine herpesvirus 1 encodes a constitutively active G-protein-coupled receptor that is non-essential for the induction of malignant catarrhal fever in rabbits (2007)

Boudry, C, Markine-Goriaynoff, N, Delforge, Cédric, Springael, JY, De Leval, L, Drion, Pierre, ...

Many gammaherpesviruses encode G-protein-coupled receptors (GPCRs). Several in vivo studies have revealed that gammaherpesvirus GPCRs are important for viral replication and for virus-induced...

Establishment and characterisation of two novel human KSHV- and EBV-negative Burkitt cell lines, GAL-01 and GAL-02, from a primary lymphomatous effusion (2006)

Thielen, Caroline, Herens, Christian, Fassotte, Marie-France, Detrooz, Elisabeth, Drion, Pierre, Diss, T, ...

Objectives: Burkitt's lymphoma (BL) is a highly aggressive mature B-cell neoplasm comprising endemic, sporadic and immunodeficiency-associated variants. Human cell lines constitute a very useful tool...

Towards a better use of the rabbit as an experimental model: review and perspectives (2006)

Dewree, R, Drion, Pierre

The rabbit is an essential model in scientific research, particularly in the study of cardiovascular diseases such as hypertension and atherosclerosis and for the investigation of the osteoarticular...

From the design to the clinical application of thromboxane modulators (2006)

Dogné, JM, Hanson, J, De Leval, X, Pratico, D, Pace-Asciak, CR, Drion, Pierre, ...

Arachidonic acid (AA) metabolites are key mediators involved in the pathogenesis of numerous cardiovascular, pulmonary, inflammatory, and thromboembolic diseases. One of these bioactive metabolites...

Utilisation raisonnable des gonadotrophines exogènes dans le contrôle de la reproduction (2005)

Drion, Pierre

De nombreuses substances pharmacologiques (tableau 1) incluant des stéroïdes, des peptides et des glycoprotéines potentiellement immunogènes sont fréquemment utilisées dans les programmes...

Characterization of an original model of myocardial infarction provoked by coronary artery thrombosis induced by ferric chloride in pig (2005)

Dogné, Jean-Michel, Rolin, Stéphanie, Pétein, Michel, Tchana-Sato, Vincent, Ghuysen, Alexandre, Lambermont, Bernard, ...

Background: Great advances have been made in the prevention of thrombotic disorders by developments of new pharmacological and surgical treatments. Animal models of arterial thrombosis have largely...

The use of blood pepsinogen as a biomarker of the integrity of the porcine gastric mucosa. 2. Measurements of blood pepsinogen and its usefull in the detection of gastric diseases (2003)

Banga-Mboko, Henri, Godeau, Jean-Marie, Drion, Pierre, Sidikou, ID, Remy, Benoit, Beckers, Jean-François

Pepsinogen is one component of the gastric juice which participes in the digestion. This macromolecule enters the blood circulation in a small measurable quantities in healthy subjects. Therefore,...

Effets du protocole GPG sur l’activité ovarienne (2003)

Hanzen, Christian, Boudry, B, Drion, Pierre

The GPG protocol or OvSynch includes an injection of GnRH and followed seven days later by an injection of PgF(2alpha), which is preceded forty-eight hours earlier by a second injection of GnRH. The...

Induction et synchronisation de l'oestrus par la PGF2alpha (2003)

Hanzen, Christian, Boudry, B, Drion, Pierre

Hormonal management of reproduction uses treatments that regulate both luteal activity and follicular growth to achieve expulsion in the shortest period of an oocyte capable of being fertilised....

From the germinal cells to the newborn animal: The transmission of genes and life through the generations (2003)

Drion, Pierre, Szenci, Otto, Ectors, Fabien, Wirth, D, Perenyi, Z, Muller, P, ...

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most...

Physiology of reproduction and endocrinology in cervids. A review (2003)

Drion, Pierre, Hanzen, Christian, Wirth, Delphine - In Memoriam, Beckers, Jean-François, Leboeuf, Bernard, Ropstad, Eric, ...

Knowledge about cervids are rapidly growing. This work aims to present the more recent scientific information on reproductive physiology and endocrinology of the cervids: anatomy of the genital...

Les protéines de choc thermique (heat shock proteins). II Les protéines de choc thermique (heat shock proteins). II. Hsp70, biomarqueur, bioprotecteur. (2003)

Wirth, Delphine, Gustin, Pascal, Drion, Pierre, Dessy, Cécile, Christiaens, E

The exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response,...

Application des prostaglandines en reproduction des espèces moins fréquentes ou de laboratoires: Souris, Rat, Hamster, Gerbille, Cobaye, Furet, Cervidés, Buffalos, Zebu, Bison (2003)

Drion, Pierre, Hanzen, Christian, Wirth, Delphine, Leboeuf, Bernard, Beckers, Jean-François

En l'an 300 avant notre ère, Herophilus d'Alexandrie fut le premier qui reconnut les ovaires comme entités propres à la femelle de la même manière que les testicules sont des attributs propres...

Signaux embryonnaires de la gestation (2002)

Sousa, N, El Amiri, B, Remy, Benoit, Drion, Pierre, Beckers, Jean-François

European Convention of the French Buiatric Society - Journées Européennes de la Société Française de Buiatrie

Heat shock proteins. I : Classification and roles in pathological processes (2002)

Wirth, D, Gustin, Pascal, Drion, Pierre, Dessy-Doize, C, Christians, ES

All living systems have evolved mechanisms to maintain homeostasis in the face of rapid environmental changes. When exposed to elevated temperatures, most of the cells activate the synthesis of a...

The use of blood pepsinogen as a biomarker of the integrity of the porcine gastric mucosa : A review. Part 1: History, physiopathology of gastric mucosa and different forms of pepsinogens (2002)

Banga-Mboko, Henri, Godeau, Jean-Marie, Drion, Pierre, El Amiri, Bouchra, Drion, Pierre, Perenyi, Zsolt, ...

Because the history is defined as the account of the passed events, this manuscript is an Update research on swine pepsinogens since their discovery by Theodor Schwann. Progress was particularly made...

Aspartic proteinase members secreted by the ruminant placenta: Specificity of three radioimmunoassay systems for the measurement of pregnancy-associated glycoproteins (2002)

Perenyi, ZS, Szenci, O, Drion, Pierre, Banga-Mboko, H, Sousa, NM, El Amiri, Bouchra, ...

Pregnancy-associated glycoproteins (PAGs) isolated from the placenta of various ruminant species are enzymatically inactive members of the aspartic proteinase family. The measurement of these...

Comparison of the ability of three radioimmunoassay to detect pregnancy-associated glycoproteins in bovine plasma (2002)

Perenyi, ZS, Szenci, Otto, Sulon, Joseph, Drion, Pierre, Beckers, Jean-François

Pregnancy-associated glycoproteins (PAGs) constitute a large family of glycoproteins that are synthesized in the superficial layer of the ruminant placenta according to a spatial and temporal...

Four years of induction/synchronization of estrus in dairy goats: effect on the evolution of eCG binding rate in relation with the parameters of reproduction (2001)

Drion, Pierre, Furtoss, V, Baril, G, Manfredi, E, Bouvier, F, Pougnard, JL, ...

Ninety-eight Alpine goats of two herds were followed over 4 years in a program of annual artificial insemination after estrus induction/synchronization, including progestagen administration (vaginal...

Increase of Plasma Ecg Binding Rate after Administration of Repeated High Dose of Ecg to Cows (2001)

Drion, Pierre, De Roover, R, Houtain, J Y, McNamara, E M, Remy, Benoit, Sulon, Joseph, ...

Equine chorionic gonadotrophin (eCG) is still used to promote follicular growth in cattle and, more recently with an increased frequency of administration, in ovum pick-up protocols. The aim of this...

Caractéristiques de la reproduction dans l’espèce caprine (2001)

Zarrouk, A, Souilem, O, Drion, Pierre, Beckers, Jean-François

This review pointed out the physiological basis of goat reproduction. So far assimilated to ewes, goats presented their own characteristics concerning the sexual activity and the endocrinology of...

Mise au point relative à la croissance folliculaire chez la vache.1. Aspects morphologiques et cinétiques (2000)

Hanzen, Christian, Lourtie, O, Derkenne, F, Drion, Pierre

La mise en place du potentiel folliculaire se fait bien avant la naissance chez les mammifères. Le nombre maximal de cellules gamétiques contenues dans l'ovaire est atteint après une première...

Pregnancy Associated Glycoproteins in Ruminants: Inactive Members of the Aspartic Proteinase Family (1999)

Beckers, Jean-François, Drion, Pierre, Garbayo, JM, Perenyi, Z, Zarrouk, A, Sulon, Joseph, ...

The Pregnancy Associated Glycoproteins (PAGs) presented in this paper are largely expressed in the ruminant placenta. These proteins are classified as probably inactive members of the aspartic...

Endocrinologie de la gestation chez les ruminants: les protéines placentaires (1998)

Zarrouk, Anissa, Remy, Benoît, Sulon, Joseph, Drion, Pierre, Desbuleux, Henri, Beckers, Jean-François

The two main groups of placental proteins of ruminants are related in this paper: Placental lactogens and Pregnancy-Specific (-Associated) Proteins. Placental lactogens belong to the prolactin and...

Utilisation répétée des gonadotropines exogènes dans le contrôle de la reproduction: justifications et effets secondaires potentiels (1998)

Drion, Pierre, Houtain, Jean-Yves, MC Namara, M, Baril, Gérard, Heyman, Yvan, Cognié, Yves, ...

Gonadotropins of pituitary origin (follitropin -FSH-, lutropin -LH-, human menopausal gonadotropin -hMG) or trophoblastic origin (human chorionic gonadotropin - hCG- also called pregnant urine...

Le clonage par transfert de noyau dans l'espèce bovine (1997)

Ectors, Fabien, Delval, Alain, Beckers, Jean-François, Drion, Pierre, Remy, Benoit, Ectors, Francis

A all in vitro cloning technique was developed in wich embryos from the first cycle nuclear transfer (cloning) were used as blastomere donor for the second cycle nuclear transfer (re-cloning). Such...

Anti-PMSG in sheep subjected annualy to oestrus synchronisation (1997)

Bodin, L, Drion, Pierre, Remy, Benoit, Brice, G, Cognié, Yves, Beckers, Jean-François

Estimation of the long-term consequences on reproduction performance of the oestrus synchronisation treatments that are annually applied to ewes was carried out on nine officially controlled dairy...

Regolazione della crescité follicolare et luteinica. Folliculogenesi e atresia. Summa (1997)

Drion, Pierre, Beckers, Jean-François, Ectors, Fabien, Hanzen, Christian, Houtain, Jean-Yves, Lonergan, P

Hypophyseal production of FSH and LH depends on a pulsating secretion of GnRH by the Hypothalamus. At the beginning of the cycle, this secretion sets free the FSH from the hypothesis responsible for...