Bacillus anthracis: Balancing innocent research with dual-use potential (2008)
Hudson, Michael J., Beyer, Wolfgang, Böhm, Reinhard, Fasanella, Antonio, Garofolo, Giuliano, Golinski, Robert, ...
Primary Involvement of Pharynx and Peyer's Patch in Inhalational and Intestinal Anthrax (2007)
Ian J. Glomski, Alejandro Piris-Gimenez, Michel Huerre, Michèle Mock, Pierre L. Goossens
Bacillus anthracis causes three forms of anthrax: inhalational, gastrointestinal, and cutaneous. Anthrax is characterized by both toxemia, which is caused by secretion of immunomodulating toxins...
Goossens, Pierre L., Marchal, Gilles, Milon, Geneviève
The recruitment of specific T lymphocytes In murine liver is thought to be a key event In the ultimate control of Listeria monocytogenes growth during primary Infection. However, there has been...
Goossens, Pierre L., Milon, Geneviève, Bevan, M.
We tested the ability of an attenuated actA mutant of Listeria monocytogenes to induce protective immunity in mice. This mutant can enter and multiply in the cytosol of the infected host cell, but is...
Soussi, Neirouz, Milon, Geneviève, Colle, Jean-Hervé, Mougneau, Evelyne, Glaichenhaus, Nicolas, Goossens, Pierre L.
Listeria monocytogenes has been used as an experimental live vector for the induction of CD8-mediated immune responses in various viral and tumoral experimental models. Susceptibility of BALB/c mice...
Saklani-Jusforgues, Hélène, Fontan, Elisabeth, Soussi, Neirouz, Milon, Geneviève, Goossens, Pierre L.
Listeria monocytogenes is considered as a potential live bacterial vector, particularly for the induction of CD8 T cells. The CD4 T-cell immune response triggered after enteral immunization of mice...
Soussi, Neirouz, Milon, Geneviève, Colle, Jean-Hervé, Mougneau, Evelyne, Glaichenhaus, Nicolas, Goossens, Pierre L.
Listeria monocytogenes has been used as an experimental live vector for the induction of CD8-mediated immune responses in various viral and tumoral experimental models. Susceptibility of BALB/c mice...
Saklani-Jusforgues, Hélène, Fontan, Elisabeth, Soussi, Neirouz, Milon, Geneviève, Goossens, Pierre L.
Listeria monocytogenes is considered as a potential live bacterial vector, particularly for the induction of CD8 T cells. The CD4 T-cell immune response triggered after enteral immunization of mice...
Primary Involvement of Pharynx and Peyer's Patch in Inhalational and Intestinal Anthrax
Glomski, Ian J, Piris-Gimenez, Alejandro, Huerre, Michel, Mock, Michèle, Goossens, Pierre L
Bacillus anthracis causes three forms of anthrax: inhalational, gastrointestinal, and cutaneous. Anthrax is characterized by both toxemia, which is caused by secretion of immunomodulating toxins...
Glomski, Ian J., Corre, Jean-Philippe, Mock, Michèle, Goossens, Pierre L.
Bacillus anthracis is a spore-forming bacterium that causes anthrax. B. anthracis has three major virulence factors, namely, lethal toxin, edema toxin, and a poly-γ-d-glutamic acid capsule. The...
Raymond, Benoit, Batsche, Eric, Boutillon, Florence, Wu, Yong-Zheng, Leduc, Dominique, Balloy, Viviane, ...
Lethal toxin (LT) is a critical virulence factor of Bacillus anthracis, the etiological agent of anthrax, whose pulmonary form is fatal in the absence of treatment. Inflammatory response is a key...
Gauthier, Yves P., Tournier, Jean-Nicolas, Paucod, Jean-Charles, Corre, Jean-Philippe, Mock, Michèle, Goossens, Pierre L., ...
Protective antigen (PA)-based anthrax vaccines acting on toxins are less effective than live attenuated vaccines, suggesting that additional antigens may contribute to protective immunity. Several...