Thulin Hedberg, Sara, Fredlund, Hans, Nicolas, Pierre, Caugant, Dominique A, Olcén, Per, Unemo, Magnus
Up-to-date information regarding the antibiotic susceptibility of Neisseria meningitidis strains from African countries is highly limited. Our aim was to comprehensively describe the antibiotic...
Pham, Viet-Laï, Cadel, Marie-Sandrine, Gouzy-Darmon, Cécile, Hanquez, Chantal, Beinfeld, Margery C, Nicolas, Pierre, ...
Abstract Background Aminopeptidase B (Ap-B; EC 3.4.11.6) catalyzes the cleavage of basic residues at the N-terminus of peptides and processes glucagon into miniglucagon. The enzyme exhibits, in vitro...
Nicolas, Pierre, Bessières, Philippe, Ehrlich, S Dusko, Maguin, Emmanuelle, Van De Guchte, Maarten
Abstract Background While genes that are conserved between related bacterial species are usually thought to have evolved along with the species, phylogenetic trees reconstructed for individual genes...
The Stem Cell Population of the Human Colon Crypt: Analysis via Methylation Patterns (2007)
Pierre Nicolas, Kyoung-Mee Kim, Darryl Shibata, Simon Tavaré
The analysis of methylation patterns is a promising approach to investigate the genealogy of cell populations in an organism. In a stem cell–niche scenario, sampled methylation patterns are the...
The Stem Cell Population of the Human Colon Crypt: Analysis via Methylation Patterns (2007)
Pierre Nicolas, Kyoung-Mee Kim, Darryl Shibata, Simon Tavare
The analysis of methylation patterns is a promising approach to investigate the genealogy of cell populations in an organism. In a stem cell niche scenario, sampled methylation patterns are the...
A model-based approach to selection of tag SNPs (2006)
Nicolas, Pierre, Sun, Fengzhu, Li, Lei M
Abstract Background Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identification of...
Auvynet, Constance, Seddiki, Nabila, Dunia, Irene, Nicolas, Pierre, Amiche, Mohammed, Lacombe, Claire
The dermal glands of the South American hylid frog Phyllomedusa bicolor synthesize and expel huge amounts of cationic, alpha-helical, 24- to 33-residue antimicrobial peptides, the dermaseptins B....
BMC Bioinformatics Methodology article A model-based approach to selection of tag SNPs (2006)
Pierre Nicolas, Fengzhu Sun, Lei M Li, Biomed Central
© 2006 Nicolas et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Analysis and modelling of effects of leaf rust and Septoria tritici blotch on wheat growth (2004)
Robert, Corinne, Bancal, Marie-Odile, Nicolas, Pierre, Lannou, Christian, Ney, Bertrand
A model to predict Septoria tritici blotch (STB) and leaf rust effects on wheat growth was constructed and evaluated in two steps. At the leaf scale, Bastiaans’ approach that predicts the relative...
Analysis and modelling of effects of leaf rust and Septoria tritici blotch on wheat growth (2004)
Robert, Corinne, Bancal, Marie-Odile, Nicolas, Pierre, Lannou, Christian, Ney, Bertrand
A model to predict Septoria tritici blotch (STB) and leaf rust effects on wheat growth was constructed and evaluated in two steps. At the leaf scale, Bastiaans’ approach that predicts the relative...
MuGeN: simultaneous exploration of multiple genomes and computer analysis results (2003)
Hoebeke, Mark, Nicolas, Pierre, Bessières, Philippe
Motivation: The availability of increasing amounts of sequence data about completely sequenced genomes spurs the development of new methods in the fields of automated annotation, and of comparative...
Mining Bacillus subtilis chromosome heterogeneities using hidden Markov models (2002)
Nicolas, Pierre, Bize, Laurent, Muri, Florence, Hoebeke, Mark, Rodolphe, François, Ehrlich, S. Dusko, ...
We present here the use of a new statistical segmentation method on the Bacillus subtilis chromosome sequence. Maximum likelihood parameter estimation of a hidden Markov model, based on the...
Duda, Thomas F., Vanhoye, Damien, Nicolas, Pierre
Antimicrobial peptides are expressed in the skin of amphibians and are used to prevent infection by microorganisms. Frog species store distinct collections of antimicrobial peptides that show...
Versailles cedex Contents (2001)
Pierre Nicolas, Florence Muri-majoube
Programs to segment DNA sequences into homogeneous regions / Recherche d’HOMogénéités dans une séquence d’ADN
De l'emploi du suc gastrique de porc dans le traitement des dyspepsies du nourrisson / (1905)
Thèse (Doctorat en Médecine)--Université de Paris.
Notes sur la vie française en Cochinchine (1900)
2 p. l., iv, 315 pp. incl. pl., port.
Zhu, Peixuan, Van Der Ende, Arie, Falush, Daniel, Brieske, Norbert, Morelli, Giovanna, Linz, Bodo, ...
The genetic variability at six polymorphic loci was examined within a global collection of 502 isolates of subgroup III, serogroup A Neisseria meningitidis. Nine “genoclouds” were identified,...
Nicolas, Pierre, Raphenon, Georges, Guibourdenche, Martine, Decousset, Laurent, Stor, Richard, Gaye, Abou Beckr
Between January and April 1998, a meningitis outbreak due to serogroup A meningococcus took place in Senegal. The outbreak began in Gandiaye, 165 km to the east of Dakar, and progressed towards the...
Mining Bacillus subtilis chromosome heterogeneities using hidden Markov models
Nicolas, Pierre, Bize, Laurent, Muri, Florence, Hoebeke, Mark, Rodolphe, François, Ehrlich, S. Dusko, ...
We present here the use of a new statistical segmentation method on the Bacillus subtilis chromosome sequence. Maximum likelihood parameter estimation of a hidden Markov model, based on the...
Nir-Paz, Ran, Prévost, Marie-Christine, Nicolas, Pierre, Blanchard, Alain, Wróblewski, Henri
Mycoplasmas, which are bacteria that are devoid of a cell wall and which belong to the class Mollicutes, are pathogenic for humans and animals and are frequent contaminants of tissue cell cultures....
Vázquez, Julio A., Arreaza, Luisa, Block, Colin, Ehrhard, Ingrid, Gray, Stephen J., Heuberger, Sigrid, ...
Previous studies have shown that there is considerable variation in the methods and media used to determine the susceptibility of Neisseria meningitidis to antimicrobial agents in different...
Lauber, Marc, Nicolas, Pierre, Boussetta, Hamadi, Fahy, Christine, Béguin, Pierre, Camier, Maryse, ...
We have tested the hypothesis that the high Mr forms common to both neurophysin and vasopressin detected in bovine neurohypophysis extracts (Nicolas, P., Camier, M., Lauber, M., Masse, M.-J. O.,...
Nicolas, Pierre, Camier, Maryse, Lauber, Marc, Masse, Marie-J. O., Möhring, Jan, Cohen, Paul
Extracts of bovine neurohypophysis made in acid/ethanol solution containing protease inhibitors were fractionated by two successive filtrations on Sephadex G-75 columns equilibrated in the presence...
Nicolas, Pierre, Norheim, Gunnstein, Garnotel, Eric, Djibo, Saacou, Caugant, Dominique A.
At the two World Health Organization Collaborating Centers for Reference and Research on Meningococci in Marseilles, France, and Oslo, Norway, the multilocus sequence typing technique was used for...
Zhu, Peixuan, Van Der Ende, Arie, Falush, Daniel, Brieske, Norbert, Morelli, Giovanna, Linz, Bodo, ...
The genetic variability at six polymorphic loci was examined within a global collection of 502 isolates of subgroup III, serogroup A Neisseria meningitidis. Nine “genoclouds” were identified,...
Nicolas, Pierre, Raphenon, Georges, Guibourdenche, Martine, Decousset, Laurent, Stor, Richard, Gaye, Abou Beckr
Between January and April 1998, a meningitis outbreak due to serogroup A meningococcus took place in Senegal. The outbreak began in Gandiaye, 165 km to the east of Dakar, and progressed towards the...
Mining Bacillus subtilis chromosome heterogeneities using hidden Markov models
Nicolas, Pierre, Bize, Laurent, Muri, Florence, Hoebeke, Mark, Rodolphe, François, Ehrlich, S. Dusko, ...
We present here the use of a new statistical segmentation method on the Bacillus subtilis chromosome sequence. Maximum likelihood parameter estimation of a hidden Markov model, based on the...
Nir-Paz, Ran, Prévost, Marie-Christine, Nicolas, Pierre, Blanchard, Alain, Wróblewski, Henri
Mycoplasmas, which are bacteria that are devoid of a cell wall and which belong to the class Mollicutes, are pathogenic for humans and animals and are frequent contaminants of tissue cell cultures....
Vázquez, Julio A., Arreaza, Luisa, Block, Colin, Ehrhard, Ingrid, Gray, Stephen J., Heuberger, Sigrid, ...
Previous studies have shown that there is considerable variation in the methods and media used to determine the susceptibility of Neisseria meningitidis to antimicrobial agents in different...
Lauber, Marc, Nicolas, Pierre, Boussetta, Hamadi, Fahy, Christine, Béguin, Pierre, Camier, Maryse, ...
We have tested the hypothesis that the high Mr forms common to both neurophysin and vasopressin detected in bovine neurohypophysis extracts (Nicolas, P., Camier, M., Lauber, M., Masse, M.-J. O.,...
Nicolas, Pierre, Camier, Maryse, Lauber, Marc, Masse, Marie-J. O., Möhring, Jan, Cohen, Paul
Extracts of bovine neurohypophysis made in acid/ethanol solution containing protease inhibitors were fractionated by two successive filtrations on Sephadex G-75 columns equilibrated in the presence...
Nicolas, Pierre, Norheim, Gunnstein, Garnotel, Eric, Djibo, Saacou, Caugant, Dominique A.
At the two World Health Organization Collaborating Centers for Reference and Research on Meningococci in Marseilles, France, and Oslo, Norway, the multilocus sequence typing technique was used for...
The Stem Cell Population of the Human Colon Crypt: Analysis via Methylation Patterns
Nicolas, Pierre, Kim, Kyoung-Mee, Shibata, Darryl, Tavaré, Simon
The analysis of methylation patterns is a promising approach to investigate the genealogy of cell populations in an organism. In a stem cell–niche scenario, sampled methylation patterns are the...
Pham, Viet-Laï, Cadel, Marie-Sandrine, Gouzy-Darmon, Cécile, Hanquez, Chantal, Beinfeld, Margery C, Nicolas, Pierre, ...
Chevalier, Jacqueline, Mulfinger, Céline, Garnotel, Eric, Nicolas, Pierre, Davin-Régli, Anne, Pagès, Jean-Marie
Population Structure of the Fish-Pathogenic Bacterium Flavobacterium psychrophilum▿
Nicolas, Pierre, Mondot, Stanislas, Achaz, Guillaume, Bouchenot, Catherine, Bernardet, Jean-François, Duchaud, Eric
Flavobacterium psychrophilum is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide, and its control mainly relies on antibiotic treatments. To...
Serogroup W135 Meningococcal Meningitis, Northern Cameroon, 2007–2008
Massenet, Denis, Inrombe, Jermias, Mevoula, Dave-Etienne, Nicolas, Pierre
We analyzed results of recent microbiologic surveillance of meningitis in northern Cameroon. During the 2007 and 2008 meningitis seasons, all 57 identified meningococcal isolates were serogroup W135....
Transcriptional landscape estimation from tiling array data using a model of signal shift and drift
Nicolas, Pierre, Leduc, Aurélie, Robin, Stéphane, Rasmussen, Simon, Jarmer, Hanne, Bessières, Philippe
Motivation: High-density oligonucleotide tiling array technology holds the promise of a better description of the complexity and the dynamics of transcriptional landscapes. In organisms such as...
Fonkoua, Marie-Christine, Taha, Muhamed-Kheir, Nicolas, Pierre, Cunin, Patrick, Alonso, Jean-Michel, Bercion, Raymond, ...
From 1991 to 1998, Neisseria meningitidis serogroups A, B, and C represented 2%-10% of strains isolated from cases of bacterial meningitis in Yaoundé. During 1999 to 2000, the percentage of...
Hedberg, Sara Thulin, Fredlund, Hans, Nicolas, Pierre, Caugant, Dominique A., Olcén, Per, Unemo, Magnus
Up-to-date information regarding the antibiotic susceptibility of Neisseria meningitidis strains from African countries is highly limited. Our aim was to comprehensively describe the antibiotic...