Dumitrescu, Bianca, Van Helden, Svenjhalmar, Ten Broeke, Rene, Nieuwenhuijzen-Kruseman, Arie, Wyers, Caroline, Udrea, Gabriela, ...
Abstract The aetiology of osteoporotic fractures is multifactorial, but little is known about the way to evaluate patients with a recent clinical fracture for the presence of secondary osteoporosis....
Heijckmann, A Caroline, Dumitrescu, Bianca, Nieuwenhuijzen Kruseman, Arie C, Geusens, Piet, Wolffenbuttel, Bruce HR, De Vries, Jolanda, ...
Abstract Background Previous studies from our group have shown that a high prevalence of vertebral deformities suggestive of fracture can be found in patients with an inflammatory disease, despite a...
GEUSENS, Piet, Roux, CH, Reid, DM, Lems, WF, Adami, S, Adachi, JD, ...
Many randomized controlled trials (RCTs) have investigated drug treatment for women at high risk of fracture, with a reduction in fracture risk as their end point. There has also been progress in...
Dinant, Geert Jan, GEUSENS, Piet, Dumitrescu, B, Van Geel, T, Van Helden, J, VANHOOF, Johan, ...
Introduction: Case finding for osteoporosis in postmenopausal women is advocated in guidelines of osteoporosis, but implementation is unsatisfactory. We studied, in daily practice, the impact of...
Van Staa, Tjeerd-Peter, Kanis, John A., Geusens, Piet, Boonen, Annelies, Leufkens, Hubert G.M., Cooper, Cyrus
OBJECTIVES: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
Osteoporosis and vertebral fractures in ankylosing spondylitis (2007)
GEUSENS, Piet, Vosse, Debby, Van Der Linden, Sjef
Diagnosing fractures of the vertebral body and its dorsal arch remains a challenge in studies and in clinical practice. Prospective studies are needed to evaluate to what degree such fractures can be...
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J., Boutsen, Y., De Clercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Catholic Univ Louvain, Brussels, Belgium. Elisabeth Ziekenhuis, Sijsele, Belgium. Univ Hasselt, BIOMED, Hasselt, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium.
Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...
Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...
Analyses of immunosenescent markers in patients with autoimmune disease (2007)
THEWISSEN, Marielle, SOMERS, Veerle, VENKEN, Koen, Van Paassen, Pieter, GEUSENS, Piet, Damoiseaux, Jan, ...
The objective of this study was to evaluate the degree of immunosenescence in patients with autoimmune disease. Tcell receptor excision circles (TREC) and the percentage of CD4(+)CD28(null) T cells...
GEUSENS, Piet, Dumitrescu, B., Willems, G., Udrea, G., Van Helden, S., ...
Univ Hosp, Div Rheumatol, Maastricht, Netherlands. Hasselt Univ, Ctr Biomed Res, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg,...
Dumitrescu, B., Van Helden, S., Nieuwenhuijzen-Kruseman, A., Wyers, C., Udrea, G., ...
Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg, Maastricht, Netherlands. Acad Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp...
GEUSENS, Piet, Dumitrescu, B., Cloet, A., Vanhoof, J.
Acad Hosp Maastricht, Maastricht, Netherlands. Hasselt Univ, Biomed Res Ctr, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Bucharest, Romania. MSD, Brussels, Belgium.
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Goemaere, S., Boutsen, Y., Declercq, L., Poriau, S., GEUSENS, Piet, Devogelaer, J. P.
Ghent Univ Hosp, Unit Osteoporosis & Metab Bone Dis, Ghent, Belgium. Catholic Univ Louvain, Univ Hosp Mont Godinne, Dept Rheumatol, Yvoir, Belgium. St Augustinus Ziekenhuis, Dept Rheumatol, Antwerp,...
Kavanaugh, A., Krueger, G. G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L. T., ...
Objective: To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis ( PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Van Staa, Tjeerd-Peter, Kanis, John A., GEUSENS, Piet, Boonen, Annelies, Leufkens, Hubert G. M., Cooper, Cyrus
Objectives: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
VAN DER HEIJDE, Desiree, Kavanaugh, A., Gladman, D. D., Antoni, C., Krueger, G. G., Guzzo, C., ...
Objective. To evaluate the effect of infliximab on progression of structural damage over I year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic...
Van Helden, Svenhjalmar, Cauberg, Evelyne, GEUSENS, Piet, Winkes, Bjorn, Van Der Weijden, Trudy, Brink, Peter
Clinical screening for osteoporosis in women aged over 50 years following a fracture is advocated by all guidelines on osteoporosis, but such attitude is widely reported to be inadequate. The aim of...
Bombardieri, S., Ruiz, A. A., Fardellone, P., GEUSENS, Piet, McKenna, F., Unnebrink, K., ...
Objective. To evaluate the effectiveness and safety of adalimumab in patients with rheumatoid arthritis (RA) who previously discontinued tumour necrosis factor (TNF) antagonists for any reason in...
Risk of falling in patients with a recent fracture (2007)
Van Helden, Svenhjalmar, Wyers, Caroline E., Dagnelie, Pieter C., Van Dongen, Martien C., Willems, Gittie, Brink, Peter R. G., ...
Background: Patients with a history of a fracture have an increased risk for future fractures, even in short term. The aim of this study was to assess the number of patients with falls and to...
Bone turnover and hip bone mineral density in patients with sarcoidosis (2007)
Heijckmann, A. Caroline, Huijberts, Maya S. P., De Vries, Jolanda, Van Der Veer, Eveline, Kruseman, Arie C. Nieuwenhuijzen, ...
Background and aim of the work: Sarcoidosis is a chronic inflammatory T-cell-driven disease can also affect bone. We evaluated bone remodelling and bone mineral density (BMD) in patients with...
Van Staa, T., GEUSENS, Piet, Zhang, B., Leufkens, H., Boonen, A., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Van Staa, Tjeerd-Peter, Kanis, John A., GEUSENS, Piet, Boonen, Annelies, Leufkens, Hubert G. M., Cooper, Cyrus
Objectives: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
VAN DER HEIJDE, Desiree, Kavanaugh, A., Gladman, D. D., Antoni, C., Krueger, G. G., Guzzo, C., ...
Objective. To evaluate the effect of infliximab on progression of structural damage over I year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic...
Van Helden, Svenhjalmar, Cauberg, Evelyne, GEUSENS, Piet, Winkes, Bjorn, Van Der Weijden, Trudy, Brink, Peter
Clinical screening for osteoporosis in women aged over 50 years following a fracture is advocated by all guidelines on osteoporosis, but such attitude is widely reported to be inadequate. The aim of...
Bombardieri, S., Ruiz, A. A., Fardellone, P., GEUSENS, Piet, McKenna, F., Unnebrink, K., ...
Objective. To evaluate the effectiveness and safety of adalimumab in patients with rheumatoid arthritis (RA) who previously discontinued tumour necrosis factor (TNF) antagonists for any reason in...
Risk of falling in patients with a recent fracture (2007)
Van Helden, Svenhjalmar, Wyers, Caroline E., Dagnelie, Pieter C., Van Dongen, Martien C., Willems, Gittie, Brink, Peter R. G., ...
Background: Patients with a history of a fracture have an increased risk for future fractures, even in short term. The aim of this study was to assess the number of patients with falls and to...
Osteoporosis and vertebral fractures in ankylosing spondylitis (2007)
GEUSENS, Piet, Vosse, Debby, Van Der Linden, Sjef
Diagnosing fractures of the vertebral body and its dorsal arch remains a challenge in studies and in clinical practice. Prospective studies are needed to evaluate to what degree such fractures can be...
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J., Boutsen, Y., De Clercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Catholic Univ Louvain, Brussels, Belgium. Elisabeth Ziekenhuis, Sijsele, Belgium. Univ Hasselt, BIOMED, Hasselt, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium.
Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...
Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...
Analyses of immunosenescent markers in patients with autoimmune disease (2007)
THEWISSEN, Marielle, SOMERS, Veerle, VENKEN, Koen, LINSEN, Loes, Van Paassen, Pieter, GEUSENS, Piet, ...
The objective of this study was to evaluate the degree of immunosenescence in patients with autoimmune disease. Tcell receptor excision circles (TREC) and the percentage of CD4(+)CD28(null) T cells...
GEUSENS, Piet, Dumitrescu, B., Willems, G., Udrea, G., Van Helden, S., ...
Univ Hosp, Div Rheumatol, Maastricht, Netherlands. Hasselt Univ, Ctr Biomed Res, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg,...
Dumitrescu, B., Van Helden, S., Nieuwenhuijzen-Kruseman, A., Wyers, C., Udrea, G., ...
Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg, Maastricht, Netherlands. Acad Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp...
GEUSENS, Piet, Dumitrescu, B., Cloet, A., Vanhoof, J.
Acad Hosp Maastricht, Maastricht, Netherlands. Hasselt Univ, Biomed Res Ctr, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Bucharest, Romania. MSD, Brussels, Belgium.
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J. P., Boutsen, Y., Declercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Ghent Univ Hosp, Unit Osteoporosis & Metab Bone Dis, Ghent, Belgium. Catholic Univ Louvain, Univ Hosp Mont Godinne, Dept Rheumatol, Yvoir, Belgium. St Augustinus Ziekenhuis, Dept Rheumatol, Antwerp,...
Kavanaugh, A., Krueger, G. G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L. T., ...
Objective: To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis ( PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Bone turnover and hip bone mineral density in patients with sarcoidosis (2007)
Heijckmann, A. Caroline, Huijberts, Maya S. P., De Vries, Jolanda, Van Der Veer, Eveline, Kruseman, Arie C. Nieuwenhuijzen, ...
Background and aim of the work: Sarcoidosis is a chronic inflammatory T-cell-driven disease can also affect bone. We evaluated bone remodelling and bone mineral density (BMD) in patients with...
Integrating a gender dimension into osteoporosis and fracture risk research (2007)
GEUSENS, Piet, Dinant, GeertJan
Background: Sex (referring to the strict biological sense) and gender (referring to the sociocultural dimension) are major determinants of health and disease. Objective: This review examines...
Kavanaugh, A., Antoni, C., Krueger, G. G., Gladman, D. D., Birbara, C., Boling, E., ...
Univ Calif San Diego, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Dept Dermatol, Salt Lake City, UT USA. Toronto...
Visvanathan, S., Deodhar, A., Braun, J., VAN DER HEIJDE, Desiree, Yan, S., Gathany, T., ...
Oregon Hlth & Sci Univ, Portland, OR 97201 USA. Rheumazentrum Ruhrgebiet, Herne, Germany. Univ Hosp Maastricht, Maastricht, Netherlands. Centocor Inc, Res & Dev, Malvern, PA 19355 USA. Univ Hasselt,...
Reducing hip fractures in an at-risk, elderly population (2006)
Masud, T., GEUSENS, Piet, Barton, I., McClung, M.
Univ Derby, Dept Musculoskeletal Gerontol, Derby, DE22 1GB England. Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Oregon Osteoporosis Ctr, Portland, OR...
Calomme, M., GEUSENS, Piet, Demeester, N., Behets, G., D'Haese, P., Sindambiwe, J., ...
Silicon (Si) deficiency in animals results in bone defects. Choline-stabilized orthosilicic acid (ch-OSA) was found to have a high bioavailability compared to other Si supplements. The effect of...
Combe, B., Codreanu, C., Fiocco, U., Gaubitz, M., GEUSENS, Piet, Kvien, T., ...
To compare the efficacy and safety of etanercept and sulfasalazine, alone and in combination, in patients with active rheumatoid arthritis despite sulfasalazine treatment.Methods: A double-blind,...
Feldtkeller, E., Vosse, D., GEUSENS, Piet
To evaluate the prevalence and annual incidence of clinically-manifest vertebral fractures among patients with ankylosing spondylitis (AS). Method: Coordinated by the Ankylosing Spondylitis...
GEUSENS, Piet, Landewe, R., Garnero, P., Chen, D., Dunstan, C., Lems, W., ...
Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal...
Review and evaluation of the Dutch guidelines for osteoporosis (2006)
GEUSENS, Piet, Lems, W., Verhaar, H., Leusink, G., Goemaere, S., Zmierczack, H., ...
Rationale At the request of a Dutch governmental organization, a multidisciplinary group of osteoporosis experts in the Netherlands published in 2002 a guideline on case finding, diagnosis,...
Kavanaugh, A., Krueger, G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L., ...
To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis (PsA) enrolled in the IMPACT 2 trial.Methods: In this double blind, placebo controlled, phase III...
Lems, W., Lodder, M., Lips, P., Bijlsma, J., GEUSENS, Piet, Schrameijer, N., ...
Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of...
Liberman, U., Hochberg, M., GEUSENS, Piet, Shah, A., Lin, J., Chattopadhyay, A., ...
A number of antiresorptive agents reduce the risk of vertebral fractures, but few have shown consistent effects on hip and other non-spine fractures. Meta-analysis provides a more precise estimate...
Risk of new clinical fractures within 2 years following a fracture (2006)
Van Helden, S., Cals, J., Kessels, F., Brink, P., Dinant, G-J., GEUSENS, Piet
Introduction:Clinical fractures are associated with an increased relative risk of future fractures, but the absolute risk and timing of new clinical fractures immediately after a clinical fracture...
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis (2006)
Van Staa, T., GEUSENS, Piet, Bijlsma, J., Leufkens, H., Cooper, C.
Objective. To determine whether patients with rheumatoid arthritis (RA) have an increased risk of fracture, and to estimate their long-term absolute fracture risk. Methods. We studied patients with...
Van Staa, T., GEUSENS, Piet, Kanis, J., Leufkens, H., Gehlbach, S.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Determinants of hyperkyphosis in patients with ankylosing spondylitis. (2006)
Vosse, D., Landewé, R., GEUSENS, Piet, Mielants, H., Dougados, M., ...
Objective: To determine clinical and radiographic determinants of hyperkyphosis in patients with ankylosing spondylitis.Methods: Spinal hyperkyphosis was assessed by occiput to wall distance (OWD) in...
Westhovens, R., Yocum, D., Han, J., Berman, A., Strusberg, I., GEUSENS, Piet, ...
OBJECTIVE: To assess the risk of serious infections following 22 weeks of infliximab therapy, and to further characterize the safety profile of infliximab in combination with background treatments...
Kung, AWC, Rovayo, R, GEUSENS, Piet, Walliser, J, Verbruggen, N, Shivaprakash, M, ...
Queen Mary Hosp, Hong Kong, Peoples R China. Cent Univ Ecuador, Eloy Alfaro, Ecuador. Univ Campus Gebouw C, Diepenbeek, Belgium. Hosp Angeles Pedregal, Padierna, Mexico. Merck & Co Inc, Brussels,...
Liberman, UA, Hochberg, MC, GEUSENS, Piet, Ross, PD
Tel Aviv Univ, Sackler Sch Med, Felsenstein Med Res Ctr, Dept Physiol & Pharmacol, IL-69978 Tel Aviv, Israel. Univ Maryland, Sch Med, Dept Med, Div Rheumatol & Clin Immunol, Baltimore, MD 21201 USA....