Progress in osteoporosis and fracture prevention: focus on postmenopausal women (2009)
Saag, Kenneth G, Geusens, Piet
Abstract In the past decade, we have witnessed a revolution in osteoporosis diagnosis and therapeutics. This includes enhanced understanding of basic bone biology, recognizing the severe consequences...
Emerging treatments for postmenopausal osteoporosis – focus on denosumab (2009)
Piet GeusensDepartment of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands and Biomedical Research Institute, University Hasselt,...
Geusens, Piet, Vanhoof, Johan, Berghs, Hubert, Praet, Johan, Esselens, Greet, ...
OBJECTIVES: To assess discrepancies between perception of Belgian rheumatologists on eligibility of RA patients for anti-TNF treatment and Belgian reimbursement criteria and to compare Belgian with...
Geusens, Piet, Vanhoof, Johan, Berghs, Hubert, Praet, Johan, Esselens, Greet, ...
Objectives. To assess discrepancies between perception of Belgian rheumatologists on eligibility of RA patients for anti-TNF treatment and Belgian reimbursement criteria and to compare Belgian with...
Geens, Elke, Geusens, Piet, Vanhoof, Johan, Berghs, Hubert, Praet, Johan, Esselens, Greet, ...
Objectives. To assess discrepancies between perception of Belgian rheumatologists on eligibility of RA patients for anti-TNF treatment and Belgian reimbursement criteria and to compare Belgian with...
Dumitrescu, Bianca, Van Helden, Svenjhalmar, Ten Broeke, Rene, Nieuwenhuijzen-Kruseman, Arie, Wyers, Caroline, Udrea, Gabriela, ...
Abstract The aetiology of osteoporotic fractures is multifactorial, but little is known about the way to evaluate patients with a recent clinical fracture for the presence of secondary osteoporosis....
Beyens, Greet, Guañabens, Núria, Papapoulos, Socrates, Karperien, Marcel, ...
Paget's Disease of Bone (PDB) is one of the most frequent metabolic bone diseases, affecting 1-5% of Western populations older than 55 years. Mutations in the sequestosome1 (SQSTM1) gene cause PDB in...
Heijckmann, A Caroline, Dumitrescu, Bianca, Nieuwenhuijzen Kruseman, Arie C, Geusens, Piet, Wolffenbuttel, Bruce HR, De Vries, Jolanda, ...
Abstract Background Previous studies from our group have shown that a high prevalence of vertebral deformities suggestive of fracture can be found in patients with an inflammatory disease, despite a...
Piet Geusens1, Willem Lems21Department of Internal Medicine, Subdivision of Rheumatology, University Hospital, Maastricht, The Netherlands and Biomedical Research Institute, University Hasselt,...
GEUSENS, Piet, Roux, CH, Reid, DM, Lems, WF, Adami, S, Adachi, JD, ...
Many randomized controlled trials (RCTs) have investigated drug treatment for women at high risk of fracture, with a reduction in fracture risk as their end point. There has also been progress in...
Dinant, Geert Jan, GEUSENS, Piet, Dumitrescu, B, Van Geel, T, Van Helden, J, VANHOOF, Johan, ...
Introduction: Case finding for osteoporosis in postmenopausal women is advocated in guidelines of osteoporosis, but implementation is unsatisfactory. We studied, in daily practice, the impact of...
Van Staa, Tjeerd-Peter, Kanis, John A., Geusens, Piet, Boonen, Annelies, Leufkens, Hubert G.M., Cooper, Cyrus
OBJECTIVES: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
Double-blinded infliximab dose escalation in patients with rheumatoid arthritis (2007)
Strusberg, Ingrid, Geusens, Piet, Berman, Alberto, Yocum, David, Baker, Daniel, ...
OBJECTIVE: To determine the efficacy, safety and pharmacokinetics of infliximab dose escalation in patients with rheumatoid arthritis (RA) who had an inadequate response to 3 mg/kg infliximab...
Osteoporosis and vertebral fractures in ankylosing spondylitis (2007)
GEUSENS, Piet, Vosse, Debby, Van Der Linden, Sjef
Diagnosing fractures of the vertebral body and its dorsal arch remains a challenge in studies and in clinical practice. Prospective studies are needed to evaluate to what degree such fractures can be...
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J., Boutsen, Y., De Clercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Catholic Univ Louvain, Brussels, Belgium. Elisabeth Ziekenhuis, Sijsele, Belgium. Univ Hasselt, BIOMED, Hasselt, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium.
Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...
Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...
Analyses of immunosenescent markers in patients with autoimmune disease (2007)
THEWISSEN, Marielle, SOMERS, Veerle, VENKEN, Koen, Van Paassen, Pieter, GEUSENS, Piet, Damoiseaux, Jan, ...
The objective of this study was to evaluate the degree of immunosenescence in patients with autoimmune disease. Tcell receptor excision circles (TREC) and the percentage of CD4(+)CD28(null) T cells...
GEUSENS, Piet, Dumitrescu, B., Willems, G., Udrea, G., Van Helden, S., ...
Univ Hosp, Div Rheumatol, Maastricht, Netherlands. Hasselt Univ, Ctr Biomed Res, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg,...
Dumitrescu, B., Van Helden, S., Nieuwenhuijzen-Kruseman, A., Wyers, C., Udrea, G., ...
Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg, Maastricht, Netherlands. Acad Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp...
GEUSENS, Piet, Dumitrescu, B., Cloet, A., Vanhoof, J.
Acad Hosp Maastricht, Maastricht, Netherlands. Hasselt Univ, Biomed Res Ctr, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Bucharest, Romania. MSD, Brussels, Belgium.
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Goemaere, S., Boutsen, Y., Declercq, L., Poriau, S., GEUSENS, Piet, Devogelaer, J. P.
Ghent Univ Hosp, Unit Osteoporosis & Metab Bone Dis, Ghent, Belgium. Catholic Univ Louvain, Univ Hosp Mont Godinne, Dept Rheumatol, Yvoir, Belgium. St Augustinus Ziekenhuis, Dept Rheumatol, Antwerp,...
Kavanaugh, A., Krueger, G. G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L. T., ...
Objective: To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis ( PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Van Staa, Tjeerd-Peter, Kanis, John A., GEUSENS, Piet, Boonen, Annelies, Leufkens, Hubert G. M., Cooper, Cyrus
Objectives: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
VAN DER HEIJDE, Desiree, Kavanaugh, A., Gladman, D. D., Antoni, C., Krueger, G. G., Guzzo, C., ...
Objective. To evaluate the effect of infliximab on progression of structural damage over I year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic...
Van Helden, Svenhjalmar, Cauberg, Evelyne, GEUSENS, Piet, Winkes, Bjorn, Van Der Weijden, Trudy, Brink, Peter
Clinical screening for osteoporosis in women aged over 50 years following a fracture is advocated by all guidelines on osteoporosis, but such attitude is widely reported to be inadequate. The aim of...
Bombardieri, S., Ruiz, A. A., Fardellone, P., GEUSENS, Piet, McKenna, F., Unnebrink, K., ...
Objective. To evaluate the effectiveness and safety of adalimumab in patients with rheumatoid arthritis (RA) who previously discontinued tumour necrosis factor (TNF) antagonists for any reason in...
Risk of falling in patients with a recent fracture (2007)
Van Helden, Svenhjalmar, Wyers, Caroline E., Dagnelie, Pieter C., Van Dongen, Martien C., Willems, Gittie, Brink, Peter R. G., ...
Background: Patients with a history of a fracture have an increased risk for future fractures, even in short term. The aim of this study was to assess the number of patients with falls and to...
Bone turnover and hip bone mineral density in patients with sarcoidosis (2007)
Heijckmann, A. Caroline, Huijberts, Maya S. P., De Vries, Jolanda, Van Der Veer, Eveline, Kruseman, Arie C. Nieuwenhuijzen, ...
Background and aim of the work: Sarcoidosis is a chronic inflammatory T-cell-driven disease can also affect bone. We evaluated bone remodelling and bone mineral density (BMD) in patients with...
Van Staa, T., GEUSENS, Piet, Zhang, B., Leufkens, H., Boonen, A., Cooper, C.
Objectives. There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. Methods. Data were...
Van Staa, Tjeerd-Peter, Kanis, John A., GEUSENS, Piet, Boonen, Annelies, Leufkens, Hubert G. M., Cooper, Cyrus
Objectives: Cost-effectiveness analyses are routinely based on data from group averages, restricting its generalizibility to those with below- or above-average risk. A pharmaco-economic model that...
VAN DER HEIJDE, Desiree, Kavanaugh, A., Gladman, D. D., Antoni, C., Krueger, G. G., Guzzo, C., ...
Objective. To evaluate the effect of infliximab on progression of structural damage over I year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic...
Van Helden, Svenhjalmar, Cauberg, Evelyne, GEUSENS, Piet, Winkes, Bjorn, Van Der Weijden, Trudy, Brink, Peter
Clinical screening for osteoporosis in women aged over 50 years following a fracture is advocated by all guidelines on osteoporosis, but such attitude is widely reported to be inadequate. The aim of...
Bombardieri, S., Ruiz, A. A., Fardellone, P., GEUSENS, Piet, McKenna, F., Unnebrink, K., ...
Objective. To evaluate the effectiveness and safety of adalimumab in patients with rheumatoid arthritis (RA) who previously discontinued tumour necrosis factor (TNF) antagonists for any reason in...
Risk of falling in patients with a recent fracture (2007)
Van Helden, Svenhjalmar, Wyers, Caroline E., Dagnelie, Pieter C., Van Dongen, Martien C., Willems, Gittie, Brink, Peter R. G., ...
Background: Patients with a history of a fracture have an increased risk for future fractures, even in short term. The aim of this study was to assess the number of patients with falls and to...
Osteoporosis and vertebral fractures in ankylosing spondylitis (2007)
GEUSENS, Piet, Vosse, Debby, Van Der Linden, Sjef
Diagnosing fractures of the vertebral body and its dorsal arch remains a challenge in studies and in clinical practice. Prospective studies are needed to evaluate to what degree such fractures can be...
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J., Boutsen, Y., De Clercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Catholic Univ Louvain, Brussels, Belgium. Elisabeth Ziekenhuis, Sijsele, Belgium. Univ Hasselt, BIOMED, Hasselt, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium.
Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...
Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...
Analyses of immunosenescent markers in patients with autoimmune disease (2007)
THEWISSEN, Marielle, SOMERS, Veerle, VENKEN, Koen, LINSEN, Loes, Van Paassen, Pieter, GEUSENS, Piet, ...
The objective of this study was to evaluate the degree of immunosenescence in patients with autoimmune disease. Tcell receptor excision circles (TREC) and the percentage of CD4(+)CD28(null) T cells...
GEUSENS, Piet, Dumitrescu, B., Willems, G., Udrea, G., Van Helden, S., ...
Univ Hosp, Div Rheumatol, Maastricht, Netherlands. Hasselt Univ, Ctr Biomed Res, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg,...
Dumitrescu, B., Van Helden, S., Nieuwenhuijzen-Kruseman, A., Wyers, C., Udrea, G., ...
Clin Hosp Dr I Cantacuzino, Dept Rheumatol, Bucharest, Romania. Univ Hosp, Dept Trauma Surg, Maastricht, Netherlands. Acad Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp...
GEUSENS, Piet, Dumitrescu, B., Cloet, A., Vanhoof, J.
Acad Hosp Maastricht, Maastricht, Netherlands. Hasselt Univ, Biomed Res Ctr, Diepenbeek, Belgium. Clin Hosp Dr I Cantacuzino, Bucharest, Romania. MSD, Brussels, Belgium.
Secondary fracture prevention measures in orthopedic wards in Belgium (2007)
Devogelaer, J. P., Boutsen, Y., Declercq, L., Poriau, S., GEUSENS, Piet, Goemaere, S.
Ghent Univ Hosp, Unit Osteoporosis & Metab Bone Dis, Ghent, Belgium. Catholic Univ Louvain, Univ Hosp Mont Godinne, Dept Rheumatol, Yvoir, Belgium. St Augustinus Ziekenhuis, Dept Rheumatol, Antwerp,...
Kavanaugh, A., Krueger, G. G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L. T., ...
Objective: To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis ( PsA) enrolled in the IMPACT 2 trial. Methods: In this double blind, placebo...
Luyten, F. P., GEUSENS, Piet, Malaise, M., De Clerck, L., Westhovens, R., Raeman, F., ...
Objective: To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare. Methods: In this 24-week, prospective, randomised,...
Bone turnover and hip bone mineral density in patients with sarcoidosis (2007)
Heijckmann, A. Caroline, Huijberts, Maya S. P., De Vries, Jolanda, Van Der Veer, Eveline, Kruseman, Arie C. Nieuwenhuijzen, ...
Background and aim of the work: Sarcoidosis is a chronic inflammatory T-cell-driven disease can also affect bone. We evaluated bone remodelling and bone mineral density (BMD) in patients with...
Integrating a gender dimension into osteoporosis and fracture risk research (2007)
GEUSENS, Piet, Dinant, GeertJan
Background: Sex (referring to the strict biological sense) and gender (referring to the sociocultural dimension) are major determinants of health and disease. Objective: This review examines...
Yocum, David, Han, John, Berman, Alberto, Strusberg, Ingrid, Geusens, Piet, ...
OBJECTIVE: To assess the risk of serious infections following 22 weeks of infliximab therapy, and to further characterize the safety profile of infliximab in combination with background treatments...
Kavanaugh, A., Antoni, C., Krueger, G. G., Gladman, D. D., Birbara, C., Boling, E., ...
Univ Calif San Diego, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Dept Dermatol, Salt Lake City, UT USA. Toronto...
Visvanathan, S., Deodhar, A., Braun, J., VAN DER HEIJDE, Desiree, Yan, S., Gathany, T., ...
Oregon Hlth & Sci Univ, Portland, OR 97201 USA. Rheumazentrum Ruhrgebiet, Herne, Germany. Univ Hosp Maastricht, Maastricht, Netherlands. Centocor Inc, Res & Dev, Malvern, PA 19355 USA. Univ Hasselt,...
Reducing hip fractures in an at-risk, elderly population (2006)
Masud, T., GEUSENS, Piet, Barton, I., McClung, M.
Univ Derby, Dept Musculoskeletal Gerontol, Derby, DE22 1GB England. Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Oregon Osteoporosis Ctr, Portland, OR...
Calomme, M., GEUSENS, Piet, Demeester, N., Behets, G., D'Haese, P., Sindambiwe, J., ...
Silicon (Si) deficiency in animals results in bone defects. Choline-stabilized orthosilicic acid (ch-OSA) was found to have a high bioavailability compared to other Si supplements. The effect of...
Combe, B., Codreanu, C., Fiocco, U., Gaubitz, M., GEUSENS, Piet, Kvien, T., ...
To compare the efficacy and safety of etanercept and sulfasalazine, alone and in combination, in patients with active rheumatoid arthritis despite sulfasalazine treatment.Methods: A double-blind,...
Feldtkeller, E., Vosse, D., GEUSENS, Piet
To evaluate the prevalence and annual incidence of clinically-manifest vertebral fractures among patients with ankylosing spondylitis (AS). Method: Coordinated by the Ankylosing Spondylitis...
GEUSENS, Piet, Landewe, R., Garnero, P., Chen, D., Dunstan, C., Lems, W., ...
Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in debilitating joint deformities with destruction of bone and cartilage. Inflammation is still considered the pivotal...
Review and evaluation of the Dutch guidelines for osteoporosis (2006)
GEUSENS, Piet, Lems, W., Verhaar, H., Leusink, G., Goemaere, S., Zmierczack, H., ...
Rationale At the request of a Dutch governmental organization, a multidisciplinary group of osteoporosis experts in the Netherlands published in 2002 a guideline on case finding, diagnosis,...
Kavanaugh, A., Krueger, G., Beutler, A., Guzzo, C., Zhou, B., Dooley, L., ...
To evaluate the efficacy and safety of infliximab through 1 year in patients with psoriatic arthritis (PsA) enrolled in the IMPACT 2 trial.Methods: In this double blind, placebo controlled, phase III...
Lems, W., Lodder, M., Lips, P., Bijlsma, J., GEUSENS, Piet, Schrameijer, N., ...
Alendronate has been described to have a bone-sparing effect in patients treated with moderate and high dosages of prednisone for heterogeneous diseases, however no data are available on groups of...
Liberman, U., Hochberg, M., GEUSENS, Piet, Shah, A., Lin, J., Chattopadhyay, A., ...
A number of antiresorptive agents reduce the risk of vertebral fractures, but few have shown consistent effects on hip and other non-spine fractures. Meta-analysis provides a more precise estimate...
Risk of new clinical fractures within 2 years following a fracture (2006)
Van Helden, S., Cals, J., Kessels, F., Brink, P., Dinant, G-J., GEUSENS, Piet
Introduction:Clinical fractures are associated with an increased relative risk of future fractures, but the absolute risk and timing of new clinical fractures immediately after a clinical fracture...
Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis (2006)
Van Staa, T., GEUSENS, Piet, Bijlsma, J., Leufkens, H., Cooper, C.
Objective. To determine whether patients with rheumatoid arthritis (RA) have an increased risk of fracture, and to estimate their long-term absolute fracture risk. Methods. We studied patients with...
Van Staa, T., GEUSENS, Piet, Kanis, J., Leufkens, H., Gehlbach, S.
Background: Simple tools are needed to identify patients at high risk of fracture. Aim: To develop a simple clinical tool for assessing 5-year risk of fracture. Design: Cohort study. Methods: The...
Determinants of hyperkyphosis in patients with ankylosing spondylitis. (2006)
Vosse, D., Landewé, R., GEUSENS, Piet, Mielants, H., Dougados, M., ...
Objective: To determine clinical and radiographic determinants of hyperkyphosis in patients with ankylosing spondylitis.Methods: Spinal hyperkyphosis was assessed by occiput to wall distance (OWD) in...
Westhovens, R., Yocum, D., Han, J., Berman, A., Strusberg, I., GEUSENS, Piet, ...
OBJECTIVE: To assess the risk of serious infections following 22 weeks of infliximab therapy, and to further characterize the safety profile of infliximab in combination with background treatments...
Kung, AWC, Rovayo, R, GEUSENS, Piet, Walliser, J, Verbruggen, N, Shivaprakash, M, ...
Queen Mary Hosp, Hong Kong, Peoples R China. Cent Univ Ecuador, Eloy Alfaro, Ecuador. Univ Campus Gebouw C, Diepenbeek, Belgium. Hosp Angeles Pedregal, Padierna, Mexico. Merck & Co Inc, Brussels,...
Liberman, UA, Hochberg, MC, GEUSENS, Piet, Ross, PD
Tel Aviv Univ, Sackler Sch Med, Felsenstein Med Res Ctr, Dept Physiol & Pharmacol, IL-69978 Tel Aviv, Israel. Univ Maryland, Sch Med, Dept Med, Div Rheumatol & Clin Immunol, Baltimore, MD 21201 USA....
Fractures, bone mineral density and bone turnover in a Dutch sarcoidosis population (2006)
Heijckmann, AC, Huijberts, MSP, De Vries, J, Wolffenbuttel, BHR, Drent, M, GEUSENS, Piet
Univ Hosp Maastricht, Maastricht, Netherlands. Hosp Bernhoven, Oss, Netherlands. Med Psychol, Tilburg, Netherlands. Univ Groningen, Med Ctr, Groningen, Netherlands. Sarcoidosis Management Ctr,...
GEUSENS, Piet, Dumitrescu, B, Cloet, A, VANHOOF, Johan
Clin Hosp Dr I Cantacuzino, Bucharest, Romania. MSD, Brussels, Belgium. Univ Hasselt, Diepenbeek, Belgium.
Risk factors for falls within the first 3 months after a fracture. (2006)
GEUSENS, Piet, Helden, SV, Wyers, C, Dagnelie, PC, Pijpers, E, Willems, G, ...
Univ Hasselt Belgium, Acad Hosp Maastricht, Maastricht, Netherlands. Maastricht Univ, Maastricht, Netherlands.
Secondary osteoporosis in patients with a recent clinical fracture. (2006)
Dumitrescu, B, Von Helden, S, Nieuwenhuijzen-Kruseman, A, Wyers, C, GEUSENS, Piet
Clin hosp, Bucharest, Romania. Univ Hasselt Belgium, Acad Hosp, Maastricht, Netherlands.
Kavanaugh, A., Antoni, C., Krueger, G. G., Gladman, D. D., Birbara, C., Boling, E., ...
Univ Calif San Diego, Div Rheumatol Allergy & Immunol, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Dept Dermatol, Salt Lake City, UT USA. Toronto...
Visvanathan, S., Deodhar, A., Braun, J., VAN DER HEIJDE, Desiree, Yan, S., Gathany, T., ...
Oregon Hlth & Sci Univ, Portland, OR 97201 USA. Rheumazentrum Ruhrgebiet, Herne, Germany. Univ Hosp Maastricht, Maastricht, Netherlands. Centocor Inc, Res & Dev, Malvern, PA 19355 USA. Univ Hasselt,...
Reducing hip fractures in an at-risk, elderly population (2006)
Masud, T., GEUSENS, Piet, Barton, I., McClung, M.
Univ Derby, Dept Musculoskeletal Gerontol, Derby, DE22 1GB England. Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Oregon Osteoporosis Ctr, Portland, OR...
Linsen, Loes, Thewissen, Marielle, Baeten, Kurt, Somers, Veerle, Geusens, Piet, Raus, Jef, ...
Abstract Natural killer T (NKT) cells have been implicated in the regulatory immune mechanisms that control autoimmunity. However, their precise role in the pathogenesis of rheumatoid arthritis (RA)...
Zhao, Jenny, Geusens, Piet, Liao, Er-Yuan, Adriaensens, Peter, Gelan, Jan, ...
Ovariectomy induces deterioration of the trabecular structure in the femoral neck of ewes, as depicted by MR microscopic imaging. This structural deterioration is prevented by salmon calcitonin...
Deodhar, A, Han, J, Williamson, P, Braun, J, VAN DER HEIJDE, Desiree, GEUSENS, Piet
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Oregon Hlth Sci Univ, Div Arthritis & Rheumat Dis, Portland, OR 97201 USA. Limberg Univ Ctr, Diepenbeek, Belgium. Centocor Inc, Biostat,...
LINSEN, Loes, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Transnatl Univ Limburg, Limburgs Univ Ctr, Biomed Onderzoeksinst, Diepenbeek, Belgium.
Van Staa, TP, Pols, HAP, De Laet, C, Leufkens, HGM, Cooper, C, GEUSENS, Piet
Background: Previous analyses of risk factors for glucocorticoid (GC)-induced osteoporosis have focused on the estimation of relative rather than absolute fracture probability. Aim: To estimate risk...
Characteristics and performance of an immunosorbent assay for human matrix Gla-protein (2005)
Teunissen, KJF, Knapen, MHJ, Kwaijtaal, M, Van Diest, R, Ketteler, M, Vermeer, C, ...
Background: Matrix gammacarboxyglutamate (Gla)-protein (MGP) is a strong inhibitor of soft tissue calcification and is mainly produced by chondrocytes and vascular smooth muscle cells (VSMCs)....
Kavanaugh, A, Krueger, GG, Birbara, C, Halter, D, De Vlam, K, Zhou, B, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Univ Massachusetts, Sch Med, Worcester, MA USA. Houston Inst Clin Res, Houston, TX USA. Limburgs Univ...
Liberman, UA, Hochberg, MC, Chattopadhyay, A, Ross, PD, GEUSENS, Piet
Tel Aviv Univ, IL-49100 Petah Tiqwa, Israel. Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Diepenbeek, Belgium. Univ Maryland, College Pk, MD 20742 USA. Merck Res Labs, Rahway, NJ USA.
Kavanaugh, A, Antoni, C, Krueger, GG, De Vlam, K, Birbara, C, Beutler, A, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Univ Limburg, Diepenbeek, Belgium. Univ Hosp Maastricht,...
Kavanaugh, A, Antoni, CE, Krueger, GG, Gladman, D, Birbara, C, Boling, EP, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Toronto Western Hosp, Toronto, ON M5T 2S8, Canada. Univ...
Kavanaugh, A, Antoni, CE, Krueger, GG, De Vlam, K, Birbara, C, Beutler, A, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp,...
Cost-effectiveness analysis of Aclasta in Paget's disease of bone in Belgium (2005)
Lecomte, P, Devogelaer, JP, Kaufman, JM, Goemaere, S, Engbersen, A, GEUSENS, Piet
Novartis Pharma, Vilvoorde, Belgium. Clin UCL St Luc, Brussels, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium. Univ Hasselt, Diepenbeek, Belgium. Novartis Pharma AG, Basel, Switzerland.
LINSEN, Loes, SOMERS, Veerle, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Limburgs Univ Ctr, Biomed Onderzoeksinst, Diepenbeek, Belgium.
LINSEN, Loes, SOMERS, Veerle, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Transnatl Univ Limburg, Biomed Onderzoeksinst, Limburgs Univ Ctr, Diepenbeek, Belgium.
LINSEN, Loes, THEWISSEN, Marielle, BAETEN, Kurt, SOMERS, Veerle, GEUSENS, Piet, RAUS, Jef, ...
Natural killer T (NKT) cells have been implicated in the regulatory immune mechanisms that control autoimmunity. However, their precise role in the pathogenesis of rheumatoid arthritis (RA) remains...
Osteoporosis and fall risk in patients with fragility fractures (2005)
Van Helden, SH, Nieuwenhuijzen-Kruseman, AC, Dinant, G, Pijpers, E, Ten Broeke, R, Brink, PR, ...
Univ Hosp, Maastricht, Netherlands. Limburgs Univ Ctr, Maastricht, Netherlands.
Jiang, Y, Zhao, J, Boonen, S, Azria, M, GEUSENS, Piet
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ San Francisco, Dept Radiol, Osteoporosis & Arthritis Res Grp, San Francisco, CA 94117 USA....
Newer drug treatments: Their effects on fracture prevention (2005)
Geusens, P, Reid, D, GEUSENS, Piet
Drug treatment of osteoporosis is based on the knowledge of mechanisms of bone turnover and the manipulation of the cellular components of bone turnover in terms of recruitment, activation and...
VDR gene polymorphism and falls in the elderly. (2005)
Bischoff-Ferrari, HA, Conzelman, M, Staehelin, HB, Theiler, R, Dick, W, GEUSENS, Piet
Brigham & Womens Hosp, Boston, MA 02115 USA. Felix Platter Hosp, Basel, Switzerland. Univ Basel, Basel, Switzerland. Triemli Hosp, Zurich, Switzerland. Limburgs Univ Ctr, Diepenbeek, Belgium.
Boonen, S, Vanderschueren, D, Haentjens, P, Mohan, S, Baylink, DJ, Bouillon, R, ...
Katholieke Univ Leuven, Univ Ziekenhuizen, Ctr Metab Bone Dis, B-3000 Louvain, Belgium. Katholieke Univ Leuven, Div Geriatr Med, B-3000 Louvain, Belgium. Katholieke Univ Leuven, Lab Expt Med &...
Effect of alendronate on the age-specific incidence of symptomatic osteoporotic fractures (2005)
Hochberg, M.C., Thompson, D.E., Black, D.M., Quandt, S.A., Cauley, J., GEUSENS, Piet, ...
Analyses of data from 3658 postmenopausal women with osteoporosis enrolled in the Fracture Intervention Trial showed that alendronate is effective in reducing the risk of symptomatic osteoporotic...
THEWISSEN, Marielle, LINSEN, Loes, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Although telomerase activity is important in normal immune function, it is unclear whether telomerase or telomerase (dys)regulation plays a role in the pathogenic immune response in autoimmune...
Premature Immunosenescence in Rheumatoid Arthritis and Multiple Sclerosis Patients (2005)
THEWISSEN, Marielle, LINSEN, Loes, SOMERS, Veerle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Patients with T-cell-mediated autoimmune diseases show immune system abnormalities that resemble the typical characteristics of autoimmune dysfunction described in the elderly. In addition, the...
Osteoporosis therapy: an example of putting evidence-based medicine into clinical practice (2005)
Hosking, D.J., GEUSENS, Piet, Rizzoli, R.
A major aim of evidence-based medicine is to assist clinical decision-making by providing the most current and reliable medical information. Systematic reviews and meta-analyses are important tools...
Watts, N.B., GEUSENS, Piet, Barton, I.P., Felsenberg, D.
Introduction: In untreated patients, low BMD correlates with increased fracture risk. Whether greater increases in BMD induced by anti-osteoporosis drugs are related to greater decreases in vertebral...
Heijckmann, A.C., Huijberts, M.S.P., GEUSENS, Piet, De Vries, J., Wolffenbuttel, B.H.R.
Objective: Untreated hyperthyroidism and treatment with high doses of thyroid hormone are associated with osteoporosis. However, their effect on bone turnover, their contribution to bone mineral...
Efficacy and Safety of Infliximab in Patients With Ankylosing Spondylitis (2005)
Dijkmans, B., GEUSENS, Piet, Sieper, J., DeWoody, K., Williamson, P., ...
Objective. The signs and symptoms of ankylosing spondylitis (AS) respond inadequately to nonsteroidal antiinflammatory drugs, corticosteroids, and diseasemodifying antirheumatic drugs in quite a...
Jiang, Y., Zhao, J., GEUSENS, Piet, Liao, E-Y., ADRIAENSENS, Peter, GELAN, Jan, ...
Ovariectomy induces deterioration of the trabecular structure in the femoral neck of ewes, as depicted by MR microscopic imaging. This structural deterioration is prevented by salmon calcitonin...
Deodhar, A, Han, J, Williamson, P, Braun, J, VAN DER HEIJDE, Desiree, GEUSENS, Piet
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Oregon Hlth Sci Univ, Div Arthritis & Rheumat Dis, Portland, OR 97201 USA. Limberg Univ Ctr, Diepenbeek, Belgium. Centocor Inc, Biostat,...
LINSEN, Loes, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Transnatl Univ Limburg, Limburgs Univ Ctr, Biomed Onderzoeksinst, Diepenbeek, Belgium.
Van Staa, TP, GEUSENS, Piet, Pols, HAP, De Laet, C, Leufkens, HGM, Cooper, C
Background: Previous analyses of risk factors for glucocorticoid (GC)-induced osteoporosis have focused on the estimation of relative rather than absolute fracture probability. Aim: To estimate risk...
Characteristics and performance of an immunosorbent assay for human matrix Gla-protein (2005)
SCHURGERS, Jo, Teunissen, KJF, Knapen, MHJ, GEUSENS, Piet, VAN DER HEIJDE, Desiree, Kwaijtaal, M, ...
Background: Matrix gammacarboxyglutamate (Gla)-protein (MGP) is a strong inhibitor of soft tissue calcification and is mainly produced by chondrocytes and vascular smooth muscle cells (VSMCs)....
Kavanaugh, A, Krueger, GG, Birbara, C, Halter, D, De Vlam, K, Zhou, B, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Univ Massachusetts, Sch Med, Worcester, MA USA. Houston Inst Clin Res, Houston, TX USA. Limburgs Univ...
Liberman, UA, Hochberg, MC, Chattopadhyay, A, Ross, PD, GEUSENS, Piet
Tel Aviv Univ, IL-49100 Petah Tiqwa, Israel. Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Diepenbeek, Belgium. Univ Maryland, College Pk, MD 20742 USA. Merck Res Labs, Rahway, NJ USA.
Kavanaugh, A, Antoni, CE, Krueger, GG, Gladman, D, Birbara, C, Boling, EP, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Toronto Western Hosp, Toronto, ON M5T 2S8, Canada. Univ...
Kavanaugh, A, Antoni, CE, Krueger, GG, De Vlam, K, Birbara, C, Beutler, A, ...
Univ Calif San Diego, La Jolla, CA 92093 USA. Univ Erlangen Nurnberg, Erlangen, Germany. Univ Utah, Hlth Sci Ctr, Salt Lake City, UT USA. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp,...
Cost-effectiveness analysis of Aclasta in Paget's disease of bone in Belgium (2005)
Lecomte, P, Devogelaer, JP, Kaufman, JM, Goemaere, S, Engbersen, A, GEUSENS, Piet
Novartis Pharma, Vilvoorde, Belgium. Clin UCL St Luc, Brussels, Belgium. State Univ Ghent Hosp, B-9000 Ghent, Belgium. Univ Hasselt, Diepenbeek, Belgium. Novartis Pharma AG, Basel, Switzerland.
LINSEN, Loes, SOMERS, Veerle, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Limburgs Univ Ctr, Biomed Onderzoeksinst, Diepenbeek, Belgium.
LINSEN, Loes, SOMERS, Veerle, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Transnatl Univ Limburg, Biomed Onderzoeksinst, Limburgs Univ Ctr, Diepenbeek, Belgium.
LINSEN, Loes, THEWISSEN, Marielle, BAETEN, Kurt, SOMERS, Veerle, GEUSENS, Piet, RAUS, Jef, ...
Natural killer T (NKT) cells have been implicated in the regulatory immune mechanisms that control autoimmunity. However, their precise role in the pathogenesis of rheumatoid arthritis (RA) remains...
Osteoporosis and fall risk in patients with fragility fractures (2005)
Van Helden, SH, Nieuwenhuijzen-Kruseman, AC, Dinant, G, Pijpers, E, Ten Broeke, R, Brink, PR, ...
Univ Hosp, Maastricht, Netherlands. Limburgs Univ Ctr, Maastricht, Netherlands.
Jiang, Y, Zhao, J, Boonen, S, Azria, M, GEUSENS, Piet
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ San Francisco, Dept Radiol, Osteoporosis & Arthritis Res Grp, San Francisco, CA 94117 USA....
Newer drug treatments: Their effects on fracture prevention (2005)
Drug treatment of osteoporosis is based on the knowledge of mechanisms of bone turnover and the manipulation of the cellular components of bone turnover in terms of recruitment, activation and...
VDR gene polymorphism and falls in the elderly. (2005)
Bischoff-Ferrari, HA, Conzelman, M, Staehelin, HB, Theiler, R, Dick, W, GEUSENS, Piet
Brigham & Womens Hosp, Boston, MA 02115 USA. Felix Platter Hosp, Basel, Switzerland. Univ Basel, Basel, Switzerland. Triemli Hosp, Zurich, Switzerland. Limburgs Univ Ctr, Diepenbeek, Belgium.
Boonen, S, Vanderschueren, D, VENKEN, Koen, GEUSENS, Piet, Haentjens, P, Mohan, S, ...
Katholieke Univ Leuven, Univ Ziekenhuizen, Ctr Metab Bone Dis, B-3000 Louvain, Belgium. Katholieke Univ Leuven, Div Geriatr Med, B-3000 Louvain, Belgium. Katholieke Univ Leuven, Lab Expt Med &...
Musculoskeletal rehabilitation in osteoporosis: a review (2004)
Sinaki, Mehrsheed, Geusens, Piet, Preisinger, Elisabeth, Minne, Helmut W
Measures of musculoskeletal rehabilitation play an integral part in the management of patients with increased fracture risk because of osteoporosis or extraskeletal risk factors. This article...
The cost-effectiveness of bone protection in patients using oral glucocorticoids. (2004)
Van Staa, TP, Leufkens, H, Pols, H, Cooper, C, GEUSENS, Piet
Procter&Gamble Pharmaceut, Egham, Surrey, England. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Utrecht, NL-3508 TC Utrecht, Netherlands. Erasmus Univ, Med Ctr, NL-3000 DR Rotterdam, Netherlands....
Van Staa, TP, Leufkens, H, Gehlbach, S, Cooper, C, GEUSENS, Piet
Procter & Gamble Co, Pharmaceut, Egham, Surrey, England. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Utrecht, NL-3508 TC Utrecht, Netherlands. Univ Southampton, Southampton SO9 5NH, Hants, England....
Ankylosing spondylitis and the risk of fracture. (2004)
Vosse, D, Cooper, C, Van Staa, TP, GEUSENS, Piet, VAN DER HEIJDE, Desiree
Univ Hosp Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium. Southampton Gen Hosp Unit, Med Res Council Environm Epidemiol, Southampton, Hants, England....
Yocum, D, Wolfe, F, Rahman, MU, Han, J, Berman, A, Strusberg, I, ...
Univ Arizona, Tucson, AZ USA. Natl Data Bank Rheum Dis, Wichita, KS USA. Centocor Inc, Malvern, PA 19355 USA. Hosp Angel C Padilla, San Miguel De Tucuman, Argentina. Ctr Reumatol Strusberg, Cordoba,...
Vosse, D, Landewe, RBM, GEUSENS, Piet, VAN DER HEIJDE, Desiree
Univ Hosp Maastricht, Div Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium.
Dijkmans, B, Sieper, J, DeWoody, K, Williamson, R, Braun, J, VAN DER HEIJDE, Desiree, ...
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Rheumatol, Amsterdam, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Free Univ Berlin,...
Clinical vertebral fractures in patients with ankylosing spondylitis (2004)
Vosse, D, Feldtkeller, E, Erlendsson, J, GEUSENS, Piet
Objective. To evaluate the prevalence and characteristics of clinically confirmed vertebral fractures (CVF) in patients with ankylosing spondylitis (AS). Methods. Coordinated by the Ankylosing...
VANDER BORGHT, Ann, LINSEN, Loes, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objective. To further understand the role of osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand (RANK-L) in rheumatoid arthritis (RA), we studied the levels of RANK-L and...
Fracture incidence after fragility fractures admitted to the hospital (2004)
Van Helden, SH, Bulstra, S, Brink, PRG, Koeyers, W, GEUSENS, Piet
Univ Limburg, Acad Hosp Maastricht, Maastricht, Netherlands. Univ Limburg, Biomed Res Inst, Diepenbeek, Belgium.
Van Der Voort, DJM, Dinant, GJ, GEUSENS, Piet
Objective: To determine the relationship between osteoporosis and the presence of specific and nonspecific medical conditions in postmenopausal women. To what, extent is this relationship useful in...
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotor Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium.
Schnitzer, TJ, Beier, J, Hasler, P, Patel, SK, Senftleber, I, Gitton, X, ...
Objective. To compare the efficacy and tolerability of the novel cyclooxygenase 2-selective inhibitor lumiracoxib with placebo and diclofenac in osteoarthritis (OA). Methods. Adults (n = 583) with...
Musculoskeletal rehabilitation in osteoporosis: A review (2004)
Pfeifer, M, Sinaki, M, Boonen, S, Preisinger, E, Minne, HW, GEUSENS, Piet
Measures of musculoskeletal rehabilitation play an integral part in the management of patients with increased fracture risk because of osteoporosis or extraskeletal risk factors. This article...
The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA (2004)
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotorisch Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Sambrook, PN, Ribot, C, Solimano, JA, Ferrer-Barriendos, J, Gaines, K, Verbruggen, N, ...
Objectives. Alendronate and raloxifene are antiresorptive agents with different mechanisms of action, each used to treat osteoporosis in postmenopausal women. This study was undertaken to compare the...
Landewe, R, Boers, M, Lems, W, Koppele, JT, Garnero, P, ...
Objective. To investigate in a randomized clinical trial setting with an aggressive combination-therapy arm and a mild-monotherapy arm, whether therapy-induced changes in urinary C-terminal...
Osteoporosis: Diagnosis and guidelines (2004)
Univ Hosp & LUC, Maastricht, Netherlands.
Performance of the OST risk tool for identifying men at risk of osteoporosis (2004)
Hochberg, MC, Adler, RA, GEUSENS, Piet
LUC, Biomed Res Inst, Diepenbeek, Belgium. Univ Maryland, Dept Med, Sch Med, Baltimore, MD 21201 USA. McGuire VA Med Ctr, Richmond, VA USA.
Efficacy, safety and tolerability of lumiracoxib in patients with rheumatoid arthritis (2004)
Alten, R, Rovensky, J, Sloan, VS, Krammer, G, Kralidis, G, Richardson, P, ...
A randomised, double-blind study was performed to assess the efficacy and tolerability of lumiracoxib in patients with rheumatoid arthritis (RA). Patients received lumiracoxib 200 mg once daily...
Landewe, R, Garnero, P, Verhoeven, A, Boers, M, GEUSENS, Piet
Univ Maastricht, Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Synarc, Mol Markers, Inserm Res Unit 403, Lyon, France. VU Univ, Med Ctr,...
De Nijs, RNJ, Lems, WF, Laan, RFJM, Struijs, A, Van Staa, TP, Bijlsma, JWJ, ...
Acad Ziekenhuis, Maastricht, Netherlands. Limburgs Univ Centrum, Diepenbeek, Belgium. Vrije Univ Amsterdam, Med Centrum Slotervaartziekenhuis, Amsterdam, Netherlands. Acad Ziekenhuis, Nijmegen,...
Effect of choline stabilized orthosilicic acid on bone density in ovariectomized rats. (2004)
Calomme, M, Sindambiwe, J, Cos, P, Vyncke, C, Vanden Berghe, D, GEUSENS, Piet
Univ Antwerp, B-2020 Antwerp, Belgium. Bio Minerals Nv, Destelbergen, Belgium. Limburgs Univ Ctr, BIOMED, Limburg, Belgium.
The cost-effectiveness of bone protection in patients using oral glucocorticoids. (2004)
Van Staa, TP, Leufkens, H, Pols, H, Cooper, C, GEUSENS, Piet
Procter&Gamble Pharmaceut, Egham, Surrey, England. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Utrecht, NL-3508 TC Utrecht, Netherlands. Erasmus Univ, Med Ctr, NL-3000 DR Rotterdam, Netherlands....
Van Staa, TP, Leufkens, H, Gehlbach, S, Cooper, C, GEUSENS, Piet
Procter & Gamble Co, Pharmaceut, Egham, Surrey, England. Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Utrecht, NL-3508 TC Utrecht, Netherlands. Univ Southampton, Southampton SO9 5NH, Hants, England....
Ankylosing spondylitis and the risk of fracture. (2004)
Vosse, D, Cooper, C, Van Staa, TP, GEUSENS, Piet, VAN DER HEIJDE, Desiree
Univ Hosp Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium. Southampton Gen Hosp Unit, Med Res Council Environm Epidemiol, Southampton, Hants, England....
Yocum, D, Wolfe, F, Rahman, MU, Han, J, Berman, A, Strusberg, I, ...
Univ Arizona, Tucson, AZ USA. Natl Data Bank Rheum Dis, Wichita, KS USA. Centocor Inc, Malvern, PA 19355 USA. Hosp Angel C Padilla, San Miguel De Tucuman, Argentina. Ctr Reumatol Strusberg, Cordoba,...
Vosse, D, Landewe, RBM, GEUSENS, Piet, VAN DER HEIJDE, Desiree
Univ Hosp Maastricht, Div Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium.
Dijkmans, B, Sieper, J, DeWoody, K, Williamson, R, Braun, J, VAN DER HEIJDE, Desiree, ...
Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Rheumatol, Amsterdam, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Free Univ Berlin,...
Clinical vertebral fractures in patients with ankylosing spondylitis (2004)
Vosse, D, Feldtkeller, E, Erlendsson, J, GEUSENS, Piet
Objective. To evaluate the prevalence and characteristics of clinically confirmed vertebral fractures (CVF) in patients with ankylosing spondylitis (AS). Methods. Coordinated by the Ankylosing...
VANDER BORGHT, Ann, LINSEN, Loes, THEWISSEN, Marielle, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objective. To further understand the role of osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand (RANK-L) in rheumatoid arthritis (RA), we studied the levels of RANK-L and...
Fracture incidence after fragility fractures admitted to the hospital (2004)
Van Helden, SH, Bulstra, S, Brink, PRG, Koeyers, W, GEUSENS, Piet
Univ Limburg, Acad Hosp Maastricht, Maastricht, Netherlands. Univ Limburg, Biomed Res Inst, Diepenbeek, Belgium.
Van Der Voort, DJM, Dinant, GJ, GEUSENS, Piet
Objective: To determine the relationship between osteoporosis and the presence of specific and nonspecific medical conditions in postmenopausal women. To what, extent is this relationship useful in...
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotor Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium.
Schnitzer, TJ, Beier, J, Hasler, P, Patel, SK, Senftleber, I, Gitton, X, ...
Objective. To compare the efficacy and tolerability of the novel cyclooxygenase 2-selective inhibitor lumiracoxib with placebo and diclofenac in osteoarthritis (OA). Methods. Adults (n = 583) with...
Musculoskeletal rehabilitation in osteoporosis: A review (2004)
Pfeifer, M, Sinaki, M, Boonen, S, Preisinger, E, Minne, HW, GEUSENS, Piet
Measures of musculoskeletal rehabilitation play an integral part in the management of patients with increased fracture risk because of osteoporosis or extraskeletal risk factors. This article...
The lunar achilles as a screening tool for osteoporosis: Comparison with spine DXA (2004)
Poriau, S, De Keyser, F, GEUSENS, Piet
Locomotorisch Centrum, Sijsele Damme, Belgium. Inst Biomed Res, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Sambrook, PN, Ribot, C, Solimano, JA, Ferrer-Barriendos, J, Gaines, K, Verbruggen, N, ...
Objectives. Alendronate and raloxifene are antiresorptive agents with different mechanisms of action, each used to treat osteoporosis in postmenopausal women. This study was undertaken to compare the...
Landewe, R, Boers, M, Lems, W, Koppele, JT, Garnero, P, ...
Objective. To investigate in a randomized clinical trial setting with an aggressive combination-therapy arm and a mild-monotherapy arm, whether therapy-induced changes in urinary C-terminal...
Osteoporosis: Diagnosis and guidelines (2004)
Univ Hosp & LUC, Maastricht, Netherlands.
Performance of the OST risk tool for identifying men at risk of osteoporosis (2004)
Hochberg, MC, Adler, RA, GEUSENS, Piet
LUC, Biomed Res Inst, Diepenbeek, Belgium. Univ Maryland, Dept Med, Sch Med, Baltimore, MD 21201 USA. McGuire VA Med Ctr, Richmond, VA USA.
Efficacy, safety and tolerability of lumiracoxib in patients with rheumatoid arthritis (2004)
Alten, R, Rovensky, J, Sloan, VS, Krammer, G, Kralidis, G, Richardson, P, ...
A randomised, double-blind study was performed to assess the efficacy and tolerability of lumiracoxib in patients with rheumatoid arthritis (RA). Patients received lumiracoxib 200 mg once daily...
Landewe, R, Garnero, P, Verhoeven, A, Boers, M, GEUSENS, Piet
Univ Maastricht, Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Synarc, Mol Markers, Inserm Res Unit 403, Lyon, France. VU Univ, Med Ctr,...
De Nijs, RNJ, Lems, WF, Laan, RFJM, Struijs, A, Van Staa, TP, Bijlsma, JWJ, ...
Acad Ziekenhuis, Maastricht, Netherlands. Limburgs Univ Centrum, Diepenbeek, Belgium. Vrije Univ Amsterdam, Med Centrum Slotervaartziekenhuis, Amsterdam, Netherlands. Acad Ziekenhuis, Nijmegen,...
Effect of choline stabilized orthosilicic acid on bone density in ovariectomized rats. (2004)
Calomme, M, Sindambiwe, J, Cos, P, Vyncke, C, Vanden Berghe, D, GEUSENS, Piet
Univ Antwerp, B-2020 Antwerp, Belgium. Bio Minerals Nv, Destelbergen, Belgium. Limburgs Univ Ctr, BIOMED, Limburg, Belgium.
Landewe, S, Vandevenne, J, GEUSENS, Piet, VANHOOF, Johan
Limburgs Univ Ctr, Clin Res Ctr Bone & joint Dis, Inst Biomed Res, Diepenbeek, Belgium. Dept Radiol, Genk, Belgium. Acad Ziekenhuis, Dept Rheumatol, Maastricht, Netherlands.Geusens, P, Limburgs Univ...
Vanhoof, J, Landewe, S, Van Wijngaerden, E, GEUSENS, Piet
Limburgs Univ Ctr, Biomed Res Inst, Clin Res Ctr Bone & Joint Dis, B-3590 Diepenbeek, Belgium. Katholieke Univ Leuven Hosp, Dept Internal Med Infect Dis, Louvain, Belgium. Acad Ziekenhuis, Dept...
Efficacy of Fosamax vs. evista comparison trial (effect-international): Results at 6 months (2003)
Sambrook, P, Keraudren, V, Gaines, K, Leung, A, Melton, M, GEUSENS, Piet
Royal N Shore Hosp, Sydney, NSW, Australia. LUC, Biomed Res Inst, Diepenbeek, Belgium. Merck & Co Inc, Whitehouse Stn, NJ USA.
Jiang, Y, Zhao, JJ, Lynch, JA, Ouyang, X, Azria, M, Genant, HK, ...
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA. Limburgs Univ Ctr, Diepenbeek, Belgium. Novartis, Basel, Switzerland.
Boers, M, Garnero, P, Landewe, R, GEUSENS, Piet, VAN DER HEIJDE, Desiree, ...
Univ Hosp Maastricht, Maastricht, Netherlands. Free Univ Amsterdam, Med Ctr, Amsterdam, Netherlands. Synarc, Lyon, France. INSERM, F-69008 Lyon, France. Limburg Univ Centrum, Diepenbeek, Belgium.
Sambrook, P, Ferrer-Barriendos, J, Ribot, C, Solimano, JA, Verbruggen, N, Gaines, K, ...
Biomed Res Inst LUC, Diepenbeek, Belgium. Univ Sydney, Sydney, NSW, Australia. Hosp Univ Cent Asturias, Oviedo, Spain. CHU Toulouse Hop Rangueil, Toulouse, France. Inst Med Miraflores, Lima, Peru....
Clinical use of a simple risk tool can improve case-finding for osteoporosis (2003)
Pols, H, Melton, M, Hochberg, MC, Ross, PD, ...
Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Masstricht, NE USA. Merck Res Labs, Rahway, NJ USA. Erasmus Med Ctr, Rotterdam, Netherlands. Univ Maryland, Baltimore, MD 21201 USA.
Risk of gastrointestinal events with bisphosphonates: Rating the evidence (2003)
Rizzoli, R, Sambrook, P, Schnitzer, T, GEUSENS, Piet
Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Maastricht, Netherlands. Univ Hosp Geneva, Geneva, Switzerland. Univ Sydney, Sydney, NSW 2006, Australia. Northwestern Univ, Chicago, IL 60611 USA.
Interaction between falls and clinical fractures. (2003)
Limburgs Univ Ctr, Diepenbeek, Belgium. State Univ Limburg Hosp, Dept Rheumatol, NL-6201 BX Maastricht, Netherlands.
Alten, R, Rovensky, J, Sloan, V, Krammer, G, Kralidis, G, Richardson, P, ...
Biomed Onderzoeksinst, Diepenbeek, Belgium. Schlosspk Klin, Berlin, Germany. Narodni Reumatol Ustav, Piestany, Slovakia. Novartis Pharmaceut Corp, E Hanover, NJ USA. Novartis Pharma AG, Basel,...
Biochemical markers of joint tissue turnover in early rheumatoid arthritis (2003)
Garnero, P, Landewe, R, GEUSENS, Piet
The progression of rheumatoid arthritis (RA), a disease characterized by synovitis, cartilage degradation and bone erosion, is highly variable from patient to patient. New specific biological markers...
Codreanu, C, Combe, B, Fiocco, U, Gaubitz, M, Kvien, T, Pavelka, K, ...
Centrul Metodol Reumatol, Bucharest, Romania. Hop Lapeyronie, Serv ImmunoRhumatol, Montpellier, France. Polyclin Univ, Cattedra Reumatol, Azienda Clin Osped Padova, Padua, Italy. Polyclin Univ, Div...
Landewe, S, Vandevenne, J, GEUSENS, Piet, VANHOOF, Johan
Limburgs Univ Ctr, Clin Res Ctr Bone & joint Dis, Inst Biomed Res, Diepenbeek, Belgium. Dept Radiol, Genk, Belgium. Acad Ziekenhuis, Dept Rheumatol, Maastricht, Netherlands.Geusens, P, Limburgs Univ...
Vanhoof, J, Landewe, S, Van Wijngaerden, E, GEUSENS, Piet
Limburgs Univ Ctr, Biomed Res Inst, Clin Res Ctr Bone & Joint Dis, B-3590 Diepenbeek, Belgium. Katholieke Univ Leuven Hosp, Dept Internal Med Infect Dis, Louvain, Belgium. Acad Ziekenhuis, Dept...
Efficacy of Fosamax vs. evista comparison trial (effect-international): Results at 6 months (2003)
Sambrook, P, Keraudren, V, Gaines, K, Leung, A, Melton, M, GEUSENS, Piet
Royal N Shore Hosp, Sydney, NSW, Australia. LUC, Biomed Res Inst, Diepenbeek, Belgium. Merck & Co Inc, Whitehouse Stn, NJ USA.
Jiang, Y, Zhao, JJ, Lynch, JA, Ouyang, X, Azria, M, Genant, HK, ...
Univ Calif San Francisco, Osteoporosis & Arthrit Res Grp, San Francisco, CA 94143 USA. Limburgs Univ Ctr, Diepenbeek, Belgium. Novartis, Basel, Switzerland.
Boers, M, Garnero, P, Landewe, R, GEUSENS, Piet, VAN DER HEIJDE, Desiree, ...
Univ Hosp Maastricht, Maastricht, Netherlands. Free Univ Amsterdam, Med Ctr, Amsterdam, Netherlands. Synarc, Lyon, France. INSERM, F-69008 Lyon, France. Limburg Univ Centrum, Diepenbeek, Belgium.
Sambrook, P, Ferrer-Barriendos, J, Ribot, C, Solimano, JA, Verbruggen, N, Gaines, K, ...
Biomed Res Inst LUC, Diepenbeek, Belgium. Univ Sydney, Sydney, NSW, Australia. Hosp Univ Cent Asturias, Oviedo, Spain. CHU Toulouse Hop Rangueil, Toulouse, France. Inst Med Miraflores, Lima, Peru....
Clinical use of a simple risk tool can improve case-finding for osteoporosis (2003)
Pols, H, Melton, M, Hochberg, MC, Ross, PD, ...
Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Masstricht, NE USA. Merck Res Labs, Rahway, NJ USA. Erasmus Med Ctr, Rotterdam, Netherlands. Univ Maryland, Baltimore, MD 21201 USA.
Risk of gastrointestinal events with bisphosphonates: Rating the evidence (2003)
Rizzoli, R, Sambrook, P, Schnitzer, T, GEUSENS, Piet
Univ Limburg, Diepenbeek, Belgium. Univ Maastricht, Maastricht, Netherlands. Univ Hosp Geneva, Geneva, Switzerland. Univ Sydney, Sydney, NSW 2006, Australia. Northwestern Univ, Chicago, IL 60611 USA.
Interaction between falls and clinical fractures. (2003)
Limburgs Univ Ctr, Diepenbeek, Belgium. State Univ Limburg Hosp, Dept Rheumatol, NL-6201 BX Maastricht, Netherlands.
Alten, R, Rovensky, J, Sloan, V, Krammer, G, Kralidis, G, Richardson, P, ...
Biomed Onderzoeksinst, Diepenbeek, Belgium. Schlosspk Klin, Berlin, Germany. Narodni Reumatol Ustav, Piestany, Slovakia. Novartis Pharmaceut Corp, E Hanover, NJ USA. Novartis Pharma AG, Basel,...
Biochemical markers of joint tissue turnover in early rheumatoid arthritis (2003)
Garnero, P, Landewe, R, GEUSENS, Piet
The progression of rheumatoid arthritis (RA), a disease characterized by synovitis, cartilage degradation and bone erosion, is highly variable from patient to patient. New specific biological markers...
Codreanu, C, Combe, B, Fiocco, U, Gaubitz, M, Kvien, T, Pavelka, K, ...
Centrul Metodol Reumatol, Bucharest, Romania. Hop Lapeyronie, Serv ImmunoRhumatol, Montpellier, France. Polyclin Univ, Cattedra Reumatol, Azienda Clin Osped Padova, Padua, Italy. Polyclin Univ, Div...
Rosen, Clifford, Sommer, Andreas, McKay, Malcolm, Rosen, David, ...
The administration of recombinant human IGF-I complexed with its predominant binding protein IGF binding protein-3 (rhIGF-I/IGFBP-3) may allow the safe administration of higher doses of IGF-I than...
Vankrieken, L, Beukeveld, J, Schreurs, C, Dinant, GJ, Durham, AP, El Shami, AS, ...
Diagnost Prod Corp, Los Angeles, CA USA. Westfries Gasthuis, Klin Chem Lab, Hoorn, Netherlands. Univ Maastricht, Capaciteitgrp Hulsarisengeneeskunde, Maastricht, Netherlands. Univ Maastricht, Fac...
Prevalence of rheumatic diseases in a rheumatological outpatient practice (2002)
Declerck, K, VANHOOF, Johan, GEUSENS, Piet
Objective: To assess the prevalence and distribution of rheumatic diseases in a community based rheumatological outpatient practice. Methods: Rheumatological diagnoses of 3751 consecutive new and...
Skeletal benefits are maintained through 7 years of alendronate treatment (2002)
Weinstein, RS, Meunier, PJ, Bone, H, Tonino, RP, Ross, PD, Santora, A, ...
Univ Arkansas Med Sci, Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USA. Hop Edouard Herriot, Lyon, France. Univ Limburg, Diepenbeek, Belgium. Michigan Bone & Mineral Clin, Detroit, MI...
Vanderborght, A, De Keyser, F, De Backer, M, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
Gamero, P, Landewe, RBM, Boers, M, Christgau, S, Van Der Linden, SJ, VAN DER HEIJDE, Desiree, ...
Synarc, INSERM, Unit 403, Lyon, France. Univ Hosp Maastricht, Maastricht, Netherlands. Nord Biosci Diagnost, Herlev, Denmark. Willems Inst, Diepenbeek, Belgium.
Landewe, R, Dunstan, C, Gaenero, P, Boers, M, GEUSENS, Piet
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands. Amgen Inc, Thousand Oaks, CA USA. INSERM, F-69008 Lyon, France. VU Univ Hosp, Amsterdam, Netherlands.
Pols, H, Siris, E, Hochberg, MC, Ross, PD, GEUSENS, Piet
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Maastricht, Maastricht, Netherlands. Erasmus Univ, Med Sch, Rotterdam, Netherlands. Columbia Univ, New York, NY 10032 USA. Univ Maryland, Baltimore, MD...
Heaney, R, Chesnut, C, Cros, M, GEUSENS, Piet, BOS, Kim
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp Maastricht, Maastricht, Netherlands. Creighton Univ, Omaha, NE 68178 USA. Univ Washington, Seattle, WA 98195 USA. Procter & Gamble Pharmaceut,...
Osteoporosis and the growth hormone-insulin-like growth factor axis (2002)
Osteoporosis is the result of an imbalance between bone resorption and bone formation. Currently, mainly drugs that inhibit bone resorption are available for the treatment of osteoporosis. A new...
Garnero, P, Landewe, R, Boers, M, Verhoeven, A, Christgau, S, ...
Objective. The known risk factors for radiologic progression in rheumatoid arthritis (RA) are not optimally discriminative in patients with early disease who do not have evidence of radiologic...
Truitt, K, Sfikakis, P, Zhao, PL, DeTora, L, Shingo, S, Lau, CS, ...
Objective: To evaluate the efficacy and tolerability of rofecoxib 25 mg and 50 mg once daily versus placebo and naproxen 500 mg twice daily in patients with RA. Methods: Eligible patients were...
Risedronate reduces the risk of first vertebral fracture in osteoporotic women (2002)
Heaney, RP, Zizic, TM, Fogelman, I, Olszynski, WP, Kasibhatla, C, Alsayed, N, ...
Risedronate treatment reduces the risk of vertebral fracture in women with existing vertebral fractures, but its efficacy in prevention of the first vertebral fracture in women with osteoporosis but...
Performance of risk indices for identifying low bone density in postmenopausal women (2002)
Hochberg, MC, Van Der Voort, DJM, Pols, H, Siris, E, Melton, ME, ...
Objective: To examine the ability of 4 published osteoporosis risk indices to identify women with low bone density. Subjects and Methods: Subjects included postmenopausal women 45 years and older...
The relationship among history of falls, osteoporosis, and fractures in postmenopausal women (2002)
Autier, P, Declerck, K, GEUSENS, Piet, RAUS, Jef, VANHOOF, Johan
Objective: To study the relative contribution of osteoporosis and falls to the occurrence of symptomatic fractures in postmenopausal women. Design: Retrospective survey of current osteoporosis in...
Effects of risedronate on risk of femoral neck and intertrochanteric fractures (2002)
Adami, S, Bensen, WG, Miller, PD, Meunier, P, GEUSENS, Piet
LUC, Inst Biomed Res, Diepenbeek, Belgium. Ctr Osped Clin Valeggio, Valeggio Sul Mincio, Italy. McMaster Univ, Hamilton, ON, Canada. Colorado Ctr Bone Res, Denver, CO USA. Hop Edouard Herriot, Lyon,...
Osteoporosis in clinical practice. One-year survey in a rheumatological unit (2002)
LUC, BIOMED, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Ankylosing spondylitis is a strong risk factor for vertebral fractures (2002)
Vosse, D, GEUSENS, Piet, VANHOOF, Johan
State Univ Limburg Hosp, NL-6201 BX Maastricht, Netherlands. LUC, BIOMED, Diepenbeek, Belgium.
Combe, BG, Codreanu, C, Fiocco, U, Gaubitz, M, Kvien, TK, Pavelka, K, ...
H Lapeyron, Montpellier, France. C Metod Reumat, Bucharest, Romania. Clin Osp, Padua, Italy. Univ Munster, D-4400 Munster, Germany. Limburgs Univ Ctr, Diepenbeek, Belgium. Dia Syk, Oslo, Norway. Inst...
Boonen, S, Rosen, C, Bouillon, R, Sommer, A, McKay, M, Rosen, D, ...
The administration of recombinant human IGF-I complexed with its predominant binding protein IGF binding protein-3 (rhIGF-I/IGFBP-3) may allow the safe administration of higher doses of IGF-I than...
BUNTINX, Mieke, AMELOOT, Marcel, STEELS, Paul, JANSSEN, Paul, MEDAER, Rob, GEUSENS, Piet, ...
Autoreactive T lymphocytes are considered to play a crucial role in orchestrating a chronic inflammation in the central nervous system (CNS) of multiple sclerosis (MS) patients and in the joints of...
Vankrieken, L, Beukeveld, J, Schreurs, C, Dinant, GJ, Durham, AP, El Shami, AS, ...
Diagnost Prod Corp, Los Angeles, CA USA. Westfries Gasthuis, Klin Chem Lab, Hoorn, Netherlands. Univ Maastricht, Capaciteitgrp Hulsarisengeneeskunde, Maastricht, Netherlands. Univ Maastricht, Fac...
Prevalence of rheumatic diseases in a rheumatological outpatient practice (2002)
Declerck, K, VANHOOF, Johan, GEUSENS, Piet
Objective: To assess the prevalence and distribution of rheumatic diseases in a community based rheumatological outpatient practice. Methods: Rheumatological diagnoses of 3751 consecutive new and...
Skeletal benefits are maintained through 7 years of alendronate treatment (2002)
Weinstein, RS, Meunier, PJ, Bone, H, Tonino, RP, Ross, PD, Santora, A, ...
Univ Arkansas Med Sci, Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USA. Hop Edouard Herriot, Lyon, France. Univ Limburg, Diepenbeek, Belgium. Michigan Bone & Mineral Clin, Detroit, MI...
Vanderborght, A, De Keyser, F, De Backer, M, Malaise, M, Baeten, D, ...
Objective. To study T cell receptor (TCR) repertoire changes in synovial membrane over a 16 week period in patients with early rheumatoid arthritis (RA); and to study the influence of cyclosporin A...
Gamero, P, Landewe, RBM, Boers, M, Christgau, S, Van Der Linden, SJ, VAN DER HEIJDE, Desiree, ...
Synarc, INSERM, Unit 403, Lyon, France. Univ Hosp Maastricht, Maastricht, Netherlands. Nord Biosci Diagnost, Herlev, Denmark. Willems Inst, Diepenbeek, Belgium.
Landewe, R, Dunstan, C, Gaenero, P, Boers, M, GEUSENS, Piet
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands. Amgen Inc, Thousand Oaks, CA USA. INSERM, F-69008 Lyon, France. VU Univ Hosp, Amsterdam, Netherlands.
Pols, H, Siris, E, Hochberg, MC, Ross, PD, GEUSENS, Piet
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Maastricht, Maastricht, Netherlands. Erasmus Univ, Med Sch, Rotterdam, Netherlands. Columbia Univ, New York, NY 10032 USA. Univ Maryland, Baltimore, MD...
Heaney, R, Chesnut, C, Cros, M, GEUSENS, Piet, BOS, Kim
Limburgs Univ Ctr, Diepenbeek, Belgium. Univ Hosp Maastricht, Maastricht, Netherlands. Creighton Univ, Omaha, NE 68178 USA. Univ Washington, Seattle, WA 98195 USA. Procter & Gamble Pharmaceut,...
Osteoporosis and the growth hormone-insulin-like growth factor axis (2002)
Osteoporosis is the result of an imbalance between bone resorption and bone formation. Currently, mainly drugs that inhibit bone resorption are available for the treatment of osteoporosis. A new...
Garnero, P, Landewe, R, Boers, M, Verhoeven, A, Christgau, S, ...
Objective. The known risk factors for radiologic progression in rheumatoid arthritis (RA) are not optimally discriminative in patients with early disease who do not have evidence of radiologic...
Truitt, K, Sfikakis, P, Zhao, PL, DeTora, L, Shingo, S, Lau, CS, ...
Objective: To evaluate the efficacy and tolerability of rofecoxib 25 mg and 50 mg once daily versus placebo and naproxen 500 mg twice daily in patients with RA. Methods: Eligible patients were...
Risedronate reduces the risk of first vertebral fracture in osteoporotic women (2002)
Heaney, RP, Zizic, TM, Fogelman, I, Olszynski, WP, Kasibhatla, C, Alsayed, N, ...
Risedronate treatment reduces the risk of vertebral fracture in women with existing vertebral fractures, but its efficacy in prevention of the first vertebral fracture in women with osteoporosis but...
Performance of risk indices for identifying low bone density in postmenopausal women (2002)
Hochberg, MC, Van Der Voort, DJM, Pols, H, Siris, E, Melton, ME, ...
Objective: To examine the ability of 4 published osteoporosis risk indices to identify women with low bone density. Subjects and Methods: Subjects included postmenopausal women 45 years and older...
The relationship among history of falls, osteoporosis, and fractures in postmenopausal women (2002)
Autier, P, Declerck, K, GEUSENS, Piet, RAUS, Jef, VANHOOF, Johan
Objective: To study the relative contribution of osteoporosis and falls to the occurrence of symptomatic fractures in postmenopausal women. Design: Retrospective survey of current osteoporosis in...
Effects of risedronate on risk of femoral neck and intertrochanteric fractures (2002)
Adami, S, Bensen, WG, Miller, PD, Meunier, P, GEUSENS, Piet
LUC, Inst Biomed Res, Diepenbeek, Belgium. Ctr Osped Clin Valeggio, Valeggio Sul Mincio, Italy. McMaster Univ, Hamilton, ON, Canada. Colorado Ctr Bone Res, Denver, CO USA. Hop Edouard Herriot, Lyon,...
Osteoporosis in clinical practice. One-year survey in a rheumatological unit (2002)
LUC, BIOMED, Diepenbeek, Belgium. Univ Hosp, Maastricht, Netherlands.
Ankylosing spondylitis is a strong risk factor for vertebral fractures (2002)
Vosse, D, GEUSENS, Piet, VANHOOF, Johan
State Univ Limburg Hosp, NL-6201 BX Maastricht, Netherlands. LUC, BIOMED, Diepenbeek, Belgium.
Combe, BG, Codreanu, C, Fiocco, U, Gaubitz, M, Kvien, TK, Pavelka, K, ...
H Lapeyron, Montpellier, France. C Metod Reumat, Bucharest, Romania. Clin Osp, Padua, Italy. Univ Munster, D-4400 Munster, Germany. Limburgs Univ Ctr, Diepenbeek, Belgium. Dia Syk, Oslo, Norway. Inst...
Boonen, S, Rosen, C, Bouillon, R, Sommer, A, McKay, M, Rosen, D, ...
The administration of recombinant human IGF-I complexed with its predominant binding protein IGF binding protein-3 (rhIGF-I/IGFBP-3) may allow the safe administration of higher doses of IGF-I than...
Risk of new vertebral fracture in the year following a fracture (2001)
Lindsay, Robert, Silverman, Stuart L., Cooper, Cyrus, Hanley, David A., Barton, Ian, Broy, Susan B., ...
Context: Vertebral fractures significantly increase lifetime risk of future fractures, but risk of further vertebral fractures in the period immediately following a vertebral fracture has not been...
Dukas, L, Bischoff, HA, Thalmann, B, Binder, K, Monsch, AU, Boos, G, ...
Geriatr Univ Clin, Basel, Switzerland. Brigham & Womens Hosp, Div Rheumatol Allergy & Immunol, Boston, Switzerland. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Univ Limburg, Acad Hosp...
Dhore, C, Daemen, M, CLEUTJENS, J., GEUSENS, Piet
Univ Maastricht, CARIM, Dept Pathol, Maastricht, Netherlands. Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium.
Recovery from severe glucocorticoid-induced osteoporosis in an adolescent boy (2001)
Menten, J, Vosse, D, Vanhoof, J, GEUSENS, Piet
An 18-yr-old boy presented with extreme back pain as the result of multiple vertebral fractures. At age 16 he had developed a tumor of the mesencephalon. A ventriculoperitoneal shunt was established...
Vandevyver, C, GEUSENS, Piet, STINISSEN, Piet, VANHOOF, Johan, RAUS, Jef, MICHIELS, Luc
Limburgs Univ Ctr, Maastricht, Netherlands. Univ Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium.
The effect of alendronate on age-specific incidence of key osteoporotic fractures (2001)
Hochberg, M, Thompson, D, Black, D, Quandt, S, Cauley, J, GEUSENS, Piet
Univ Maryland, Baltimore, MD 21201 USA. Merck & Co Inc, Rahway, NJ 07065 USA. Univ Calif San Francisco, San Francisco, CA 94143 USA. Wake Forest Univ, Winston Salem, NC 27109 USA. Univ Pittsburgh,...
Vosse, D, Vanhoof, J, GEUSENS, Piet, VAN DER HEIJDE, Desiree, RAUS, Jef
Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium.
Effect of risedronate on the risk of hip fracture in elderly women (2001)
McClung, MR, Miller, PD, Zippel, H, Bensen, WG, Roux, C, Adami, S, ...
Background: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. Methods: We studied 5445 women 70 to 79 years old who had osteoporosis...
VANDER BORGHT, Ann, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objectives: To review the role of T lymphocytes in the pathogenesis of rheumatoid arthritis (RA) and discuss the relevance of the components of the trimolecular complex (synovial T cells,...
Verhoeven, AC, Boers, M, Koppele, JMT, Van Der Laan, WH, Markusse, HM, ...
Objectives. Exploration or bone metabolism changes at different levels of disease activity, both with and without oral corticosteroid therapy, and prediction of changes in joint damage and bone...
Siris, E, Pols, H, Byrnes, C, Turpin, J, Melton, M, Ross, P, ...
Columbia Univ, New York, NY USA. Univ Limburg, Diepenbeek, Belgium. Erasmus Univ, Sch Med, Rotterdam, Netherlands. Merck Res Labs, Rahway, NJ USA.
Skeletal benefits are maintained through 7 years of alendronate treatment. (2001)
Weinstein, R, Meunier, PJ, Bone, H, Tonino, RP, Ross, PD, Santora, A, ...
Univ Arkansas Med Sci, Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USA. Hop Edouard Herriot, Lyon, France. Univ Limburg, Diepenbeek, Belgium. Michigan Bone & Mineral Clin, Detroit, MI...
Watts, NB, Jenkins, DK, Visor, JM, Casal, DC, GEUSENS, Piet
Alendronate therapy in osteoporotic women decreases bone turnover and increases bone mineral density (BMD). Optimal patient management should include verification that each patient is responding to...
Dukas, L, Bischoff, HA, Thalmann, B, Binder, K, Monsch, AU, Boos, G, ...
Geriatr Univ Clin, Basel, Switzerland. Brigham & Womens Hosp, Div Rheumatol Allergy & Immunol, Boston, Switzerland. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Univ Limburg, Acad Hosp...
Dhore, C, Daemen, M, CLEUTJENS, J., GEUSENS, Piet
Univ Maastricht, CARIM, Dept Pathol, Maastricht, Netherlands. Univ Hosp Maastricht, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium.
Recovery from severe glucocorticoid-induced osteoporosis in an adolescent boy (2001)
Menten, J, Vosse, D, Vanhoof, J, GEUSENS, Piet
An 18-yr-old boy presented with extreme back pain as the result of multiple vertebral fractures. At age 16 he had developed a tumor of the mesencephalon. A ventriculoperitoneal shunt was established...
Vandevyver, C, GEUSENS, Piet, STINISSEN, Piet, VANHOOF, Johan, RAUS, Jef, MICHIELS, Luc
Limburgs Univ Ctr, Maastricht, Netherlands. Univ Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium.
The effect of alendronate on age-specific incidence of key osteoporotic fractures (2001)
Hochberg, M, Thompson, D, Black, D, Quandt, S, Cauley, J, GEUSENS, Piet
Univ Maryland, Baltimore, MD 21201 USA. Merck & Co Inc, Rahway, NJ 07065 USA. Univ Calif San Francisco, San Francisco, CA 94143 USA. Wake Forest Univ, Winston Salem, NC 27109 USA. Univ Pittsburgh,...
Vosse, D, Vanhoof, J, GEUSENS, Piet, VAN DER HEIJDE, Desiree, RAUS, Jef
Univ Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, Diepenbeek, Belgium.
Effect of risedronate on the risk of hip fracture in elderly women (2001)
McClung, MR, Miller, PD, Zippel, H, Bensen, WG, Roux, C, Adami, S, ...
Background: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. Methods: We studied 5445 women 70 to 79 years old who had osteoporosis...
VANDER BORGHT, Ann, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objectives: To review the role of T lymphocytes in the pathogenesis of rheumatoid arthritis (RA) and discuss the relevance of the components of the trimolecular complex (synovial T cells,...
Verhoeven, AC, Boers, M, Koppele, JMT, Van Der Laan, WH, Markusse, HM, ...
Objectives. Exploration or bone metabolism changes at different levels of disease activity, both with and without oral corticosteroid therapy, and prediction of changes in joint damage and bone...
Siris, E, Pols, H, Byrnes, C, Turpin, J, Melton, M, Ross, P, ...
Columbia Univ, New York, NY USA. Univ Limburg, Diepenbeek, Belgium. Erasmus Univ, Sch Med, Rotterdam, Netherlands. Merck Res Labs, Rahway, NJ USA.
Skeletal benefits are maintained through 7 years of alendronate treatment. (2001)
Weinstein, R, Meunier, PJ, Bone, H, Tonino, RP, Ross, PD, Santora, A, ...
Univ Arkansas Med Sci, Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USA. Hop Edouard Herriot, Lyon, France. Univ Limburg, Diepenbeek, Belgium. Michigan Bone & Mineral Clin, Detroit, MI...
Watts, NB, Jenkins, DK, Visor, JM, Casal, DC, GEUSENS, Piet
Alendronate therapy in osteoporotic women decreases bone turnover and increases bone mineral density (BMD). Optimal patient management should include verification that each patient is responding to...
Influence of VDR polymorphism on muscle strength in elderly men (2000)
Bischoff, HA, Dick, W, Theiler, R, Stahelin, HB, GEUSENS, Piet, MICHIELS, Luc
Univ Basel, Basel, Switzerland. Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Univ Limburg, Biomed Res Inst, Diepenbeek, Belgium.
Adachi, JD, Roux, C, Pitt, PI, Cooper, C, Moniz, C, Dequeker, J, ...
Objective. To conduct a pooled data analysis in a group of patients defined by sex, menopausal status, and underlying disease in order to examine the effect of intermittent cyclical etidronate in the...
Hosking, D, Bockman, R, Glowinski, J, Moreland, L, Ernst, T, Smith, C, ...
City Hosp Nottingham, Nottingham, England. Hosp Special Surg, New York, NY 10021 USA. Ctr Hosp, Gonesse, France. Univ Alabama, Birmingham, AL USA. Procter & Gamble Pharmaceut, Mason, OH USA. Univ...
High prevalence of vertebral deformities in hyperkyphosis of ankylosing spondylitis. (2000)
Vosse, D, GEUSENS, Piet, VAN DER HEIJDE, Desiree, VANHOOF, Johan, RAUS, Jef
Univ Maastricht, Maastricht, Netherlands. Limburg Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium.
Influence of immobility on bone remodeling and muscle strength in elderly persons. (2000)
Univ Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Harvard Univ, Boston, MA 02115 USA.
Hypogonadism is a complication of glucocorticoid therapy. Postmenopausal women on glucocorticoids suffer more fractures than premenopausal women on glucocorticoids. The use of oral contraceptives has...
Vertebral wedging and spinal deformity in ankylosing spondylitis (2000)
Vosse, D, GEUSENS, Piet, VANHOOF, Johan, VAN DER HEIJDE, Desiree, RAUS, Jef
Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium.
Verhoeven, AC, Boers, M, Te Koppele, JM, Markusse, HM, ...
Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Vrije Univ Amsterdam, Univ Hosp, Amsterdam, Netherlands. TNO, Prevent &...
Declerck, K, Bischoff, H, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium. Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Univ Basel, Dept Orthopaed Rheumatol & Geriatr, Basel, Switzerland.
Algodystrophy is a clinical syndrome characterized by intense locoregional pain, vasomotor and trophic changes and delayed recovery, mostly occurring after trauma or surgery. The variety of...
Vandevyver, C, VANDER BORGHT, Ann, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objective. Autoreactive T cells may contribute to the pathogenesis of rheumatoid arthritis (RA). We studied the T-cell receptor (TCR) V-gene repertoire in the blood and synovium of early and chronic...
Watts, NB, Jenkins, DK, GEUSENS, Piet
Emory Univ, Sch Med, Atlanta, GA USA. Metra Biosyst, Mt View, CA USA. Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium. Maastricht Univ, Dept Rheumatol, Maastricht, Netherlands.
Influence of VDR polymorphism on muscle strength in elderly men (2000)
Bischoff, HA, Dick, W, Theiler, R, Stahelin, HB, GEUSENS, Piet, MICHIELS, Luc
Univ Basel, Basel, Switzerland. Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Univ Limburg, Biomed Res Inst, Diepenbeek, Belgium.
Adachi, JD, Roux, C, Pitt, PI, Cooper, C, Moniz, C, Dequeker, J, ...
Objective. To conduct a pooled data analysis in a group of patients defined by sex, menopausal status, and underlying disease in order to examine the effect of intermittent cyclical etidronate in the...
Hosking, D, Bockman, R, Glowinski, J, Moreland, L, Ernst, T, Smith, C, ...
City Hosp Nottingham, Nottingham, England. Hosp Special Surg, New York, NY 10021 USA. Ctr Hosp, Gonesse, France. Univ Alabama, Birmingham, AL USA. Procter & Gamble Pharmaceut, Mason, OH USA. Univ...
High prevalence of vertebral deformities in hyperkyphosis of ankylosing spondylitis. (2000)
Vosse, D, GEUSENS, Piet, VAN DER HEIJDE, Desiree, VANHOOF, Johan, RAUS, Jef
Univ Maastricht, Maastricht, Netherlands. Limburg Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium.
Influence of immobility on bone remodeling and muscle strength in elderly persons. (2000)
Univ Maastricht, Maastricht, Netherlands. Limburgs Univ Ctr, Diepenbeek, Belgium. Harvard Univ, Boston, MA 02115 USA.
Hypogonadism is a complication of glucocorticoid therapy. Postmenopausal women on glucocorticoids suffer more fractures than premenopausal women on glucocorticoids. The use of oral contraceptives has...
Vertebral wedging and spinal deformity in ankylosing spondylitis (2000)
Vosse, D, GEUSENS, Piet, VANHOOF, Johan, VAN DER HEIJDE, Desiree, RAUS, Jef
Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium.
Verhoeven, AC, Boers, M, Te Koppele, JM, Markusse, HM, ...
Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Limburgs Univ Ctr, Biomed Res Inst, Diepenbeek, Belgium. Vrije Univ Amsterdam, Univ Hosp, Amsterdam, Netherlands. TNO, Prevent &...
Declerck, K, Bischoff, H, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium. Maastricht Univ, Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Univ Basel, Dept Orthopaed Rheumatol & Geriatr, Basel, Switzerland.
Algodystrophy is a clinical syndrome characterized by intense locoregional pain, vasomotor and trophic changes and delayed recovery, mostly occurring after trauma or surgery. The variety of...
Vandevyver, C, VANDER BORGHT, Ann, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
Objective. Autoreactive T cells may contribute to the pathogenesis of rheumatoid arthritis (RA). We studied the T-cell receptor (TCR) V-gene repertoire in the blood and synovium of early and chronic...
Watts, NB, Jenkins, DK, GEUSENS, Piet
Emory Univ, Sch Med, Atlanta, GA USA. Metra Biosyst, Mt View, CA USA. Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium. Maastricht Univ, Dept Rheumatol, Maastricht, Netherlands.
Boonen, A, Schoon, E, Declerck, K, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium. Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp, Dept Gastroenterol, Maastricht, Netherlands.
Perspectives on bone mechanical properties and adaptive response to mechanical challenge (1999)
Jiang, YB, Zhao, J, Rosen, C, Genant, HK, GEUSENS, Piet
The bones of the human skeleton serve a mechanical function besides providing a reservoir for calcium and hematopoietic homeostasis. When mechanically challenged, they usually respond and adapt;...
High prevalence of uncorrected non-skeletal risk factors for hip fracture in nursing homes. (1999)
Declerck, K, Vaes, G, Thone, L, Viaene, M, Wertelaers, A, Boonen, A, ...
Limburgs Univ Ctr, DWI, Biomed Res Inst, Diepenbeek, Belgium. Univ Maastricht, Dept Rheumatol, Maastricht, Netherlands. OSTEOLIMB Working Grp, Limburgerhof, Germany. Univ Maastricht, Dept...
Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium. Univ Maastricht, Dept Rheumatol, Maastricht, Netherlands. Univ Basel, Orthopad Klin, Basel, Switzerland.
Vandevyver, C, Declerck, K, Cassiman, JJ, Boonen, S, VANHOOF, Johan, STINISSEN, Piet, ...
The PvuII polymorphism of the estrogen receptor (ESR) gene and its relation to bone mineral density (BMD), fracture history, and muscle strength was studied in 313 postmenopausal (76 +/- 5 years)...
Vandevyver, C, VANDER BORGHT, Ann, VAN DER AA, Annegret, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
The analysis of T cell receptor variable (TCR V) gene repertoires in blood or tissues may provide important information when studying immunopathological mechanisms. The overexpression of a TCR gene...
Boonen, A, Schoon, E, Declerck, K, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Limburgs Univ Ctr, Inst Biomed Res, DWI, Diepenbeek, Belgium. Acad Hosp, Dept Rheumatol, Maastricht, Netherlands. Acad Hosp, Dept Gastroenterol, Maastricht, Netherlands.
Perspectives on bone mechanical properties and adaptive response to mechanical challenge (1999)
Jiang, YB, Zhao, J, Rosen, C, Genant, HK, GEUSENS, Piet
The bones of the human skeleton serve a mechanical function besides providing a reservoir for calcium and hematopoietic homeostasis. When mechanically challenged, they usually respond and adapt;...
High prevalence of uncorrected non-skeletal risk factors for hip fracture in nursing homes. (1999)
Declerck, K, Vaes, G, Thone, L, Viaene, M, Wertelaers, A, Boonen, A, ...
Limburgs Univ Ctr, DWI, Biomed Res Inst, Diepenbeek, Belgium. Univ Maastricht, Dept Rheumatol, Maastricht, Netherlands. OSTEOLIMB Working Grp, Limburgerhof, Germany. Univ Maastricht, Dept...
Limburgs Univ Ctr, Biomed Res Inst DWI, Diepenbeek, Belgium. Univ Maastricht, Dept Rheumatol, Maastricht, Netherlands. Univ Basel, Orthopad Klin, Basel, Switzerland.
Vandevyver, C, Declerck, K, Cassiman, JJ, Boonen, S, VANHOOF, Johan, STINISSEN, Piet, ...
The PvuII polymorphism of the estrogen receptor (ESR) gene and its relation to bone mineral density (BMD), fracture history, and muscle strength was studied in 313 postmenopausal (76 +/- 5 years)...
Vandevyver, C, VANDER BORGHT, Ann, VAN DER AA, Annegret, GEUSENS, Piet, RAUS, Jef, STINISSEN, Piet
The analysis of T cell receptor variable (TCR V) gene repertoires in blood or tissues may provide important information when studying immunopathological mechanisms. The overexpression of a TCR gene...
The availability of bone densitometry in daily clinical practice has revolutionized the capacity to detect osteoporosis, to estimate the risk of future fracture, and to select those patients who are...
Dequeker, J, Stalmans, R, Boonen, S, Joly, J, Nijs, J, GEUSENS, Piet, ...
Objective-To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. Methods-A double blind, randomised placebo controlled study comparing cyclic...
Jiang, Y, Zhao, J, Genant, HK, Dequeker, J, GEUSENS, Piet
Prostaglandins have been reported to mediate the effects of ovariectomy on bone loss. We studied the effect of naproxen, an inhibitor of production of prostaglandins, on ovariectomy-induced bone...
Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma (1998)
Pauwels, RA, Yernault, JC, Demedts, MG, GEUSENS, Piet
There are still some concerns about the safety of high doses of inhaled glucocorticosteroids (ICS). We compared the safety and efficacy of fluticasone propionate (FP) and beclomethasone dipropionate...
The availability of bone densitometry in daily clinical practice has revolutionized the capacity to detect osteoporosis, to estimate the risk of future fracture, and to select those patients who are...
Dequeker, J, Stalmans, R, Boonen, S, Joly, J, Nijs, J, GEUSENS, Piet, ...
Objective-To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. Methods-A double blind, randomised placebo controlled study comparing cyclic...
Jiang, Y, Zhao, J, Genant, HK, Dequeker, J, GEUSENS, Piet
Prostaglandins have been reported to mediate the effects of ovariectomy on bone loss. We studied the effect of naproxen, an inhibitor of production of prostaglandins, on ovariectomy-induced bone...
Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma (1998)
Pauwels, RA, Yernault, JC, Demedts, MG, GEUSENS, Piet
There are still some concerns about the safety of high doses of inhaled glucocorticosteroids (ICS). We compared the safety and efficacy of fluticasone propionate (FP) and beclomethasone dipropionate...
Vandevyver, C, Cassiman, JJ, Boonen, S, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Osteoporotic fragility fractures are related to bone density and injury, which are both related to muscle strength, The influence of genetic factors, such as the vitamin D receptor (VDR) polymorphism...
Boonen, S, Vanderschueren, D, Bouillon, R, GEUSENS, Piet
Osteoporotic fractures, and especially hip fractures, are a leading cause of morbidity and mortality among elderly men. Among other factors, a decline in bone mass has been identified as the major...
Vandevyver, C, Cassiman, JJ, Philippaerts, L, Mertens, J, GEUSENS, Piet, VANHOOF, Johan, ...
DR WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CTR,DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,CENTRUM MENSELIJKE ERFELIJKHEID,B-3001 LOUVAIN,BELGIUM.
Treatment with etidronate for men with idiopathic osteoporosis (1997)
Dequeker, J, Nijs, J, Joly, J, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
KATHOLIEKE UNIV LEUVEN,ARTHRIT & METAB BONE DIS RES UNIT,B-3001 LOUVAIN,BELGIUM.Geusens, P, LIMBURGS UNIV CTR,DR L WILLEMS INST,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM.
Celis, L, Vandevyver, C, Dequeker, J, Zhang, JW, GEUSENS, Piet, RAUS, Jef
Objective. To examine the reactivity pattern and T cell receptor (TCR) characteristics of mycobacterial heat-shock protein 65 (hsp65)-reactive T cells generated from paired synovial fluid (SF) and...
Jiang, YB, Zhao, HK, Genant, HK, Dequeker, J, GEUSENS, Piet
To study the long-term effect of aging, low calcium diet (LCD) and/or ovariectomy (OVX), and estrogen replacement therapy (+E) on rat bone quality of both trabecular and cortical bone, 150 female...
Vandevyver, C, Cassiman, JJ, PHILIPPAERTS, Linda, RAUS, Jef, GEUSENS, Piet
WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CTR,DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,CTR MENSELIJKE ERFELIJKHEID,B-3001 LOUVAIN,BELGIUM.
Vandevyver, C, Wylin, T, Cassiman, JJ, RAUS, Jef, GEUSENS, Piet
It is well established that genetic factors contribute to bone turnover and bone density, Evidence exists suggesting that a major part of this genetic influence may be due to polymorphisms in the...
Vandevyver, C, Cassiman, JJ, Boonen, S, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
Osteoporotic fragility fractures are related to bone density and injury, which are both related to muscle strength, The influence of genetic factors, such as the vitamin D receptor (VDR) polymorphism...
Boonen, S, Vanderschueren, D, Bouillon, R, GEUSENS, Piet
Osteoporotic fractures, and especially hip fractures, are a leading cause of morbidity and mortality among elderly men. Among other factors, a decline in bone mass has been identified as the major...
Vandevyver, C, Cassiman, JJ, Philippaerts, L, Mertens, J, GEUSENS, Piet, VANHOOF, Johan, ...
DR WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CTR,DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,CENTRUM MENSELIJKE ERFELIJKHEID,B-3001 LOUVAIN,BELGIUM.
Treatment with etidronate for men with idiopathic osteoporosis (1997)
Dequeker, J, Nijs, J, Joly, J, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
KATHOLIEKE UNIV LEUVEN,ARTHRIT & METAB BONE DIS RES UNIT,B-3001 LOUVAIN,BELGIUM.Geusens, P, LIMBURGS UNIV CTR,DR L WILLEMS INST,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM.
Celis, L, Vandevyver, C, Dequeker, J, GEUSENS, Piet, RAUS, Jef, Zhang, JW
Objective. To examine the reactivity pattern and T cell receptor (TCR) characteristics of mycobacterial heat-shock protein 65 (hsp65)-reactive T cells generated from paired synovial fluid (SF) and...
Jiang, YB, Zhao, HK, Genant, HK, Dequeker, J, GEUSENS, Piet
To study the long-term effect of aging, low calcium diet (LCD) and/or ovariectomy (OVX), and estrogen replacement therapy (+E) on rat bone quality of both trabecular and cortical bone, 150 female...
Vandevyver, C, Cassiman, JJ, PHILIPPAERTS, Linda, RAUS, Jef, GEUSENS, Piet
WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CTR,DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,CTR MENSELIJKE ERFELIJKHEID,B-3001 LOUVAIN,BELGIUM.
Vandevyver, C, Wylin, T, Cassiman, JJ, RAUS, Jef, GEUSENS, Piet
It is well established that genetic factors contribute to bone turnover and bone density, Evidence exists suggesting that a major part of this genetic influence may be due to polymorphisms in the...
Geometric characteristics of the proximal femur and hip fracture risk (1996)
Geusens, P, LIMBURGS UNIV CTR,DR L WILLEMS INST,CLIN RES CTR BONE & JOINT DIS,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM.
Effect of salmon calcitonin on femoral bone quality in adult ovariectomized ewes (1996)
Boonen, S, Nijs, J, Jiang, Y, Lowet, G, VanAuderkercke, R, Huyghe, C, ...
The aim of this study was to evaluate the effect of intermittent calcitonin on femoral bone quality in adult ewes from the time of ovariectomy. Six months after the start of the experiment, bone...
Heterogeneity of bone loss and loss of muscle strength in elderly women. (1996)
GEUSENS, Piet, VANHOOF, Johan, MERTENS, Johan, RAUS, Jef
DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3590 DIEPENBEEK,BELGIUM.
Falls, benzodiazepines and fractures in post-menopausal women (1996)
Hemmer, P, Kegelaers, G, Autier, P, GEUSENS, Piet
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,LIMBURGERHOF,GERMANY.
Detection of women at risk for osteoporosis in general practice. (1996)
Coppens, E, Autier, P, GEUSENS, Piet, VANHOOF, Johan
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,B-3610 DIEPENBEEK,BELGIUM. INST JULES BORDET,BRUSSELS,BELGIUM.
GEUSENS, Piet, VANHOOF, Johan, VANDERVORST, Carine, RAUS, Jef, Vankrieken, L
DR WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,DIEPENBEEK,BELGIUM. DIAGNOST PROD CORP,LOS ANGELES,CA.
Devogelaer, JP, Broll, H, CorreaRotter, R, Cumming, DC, DeDeuxchaisnes, CN, Hosking, D, ...
To determine the effects of long-term daily oral alendronate sodium (ALN) on bone mass in postmenopausal women with osteoporosis, 19 centers enrolled 516 postmenopausal women aged 45-80 gears with...
Geometric characteristics of the proximal femur and hip fracture risk (1996)
Geusens, P, LIMBURGS UNIV CTR,DR L WILLEMS INST,CLIN RES CTR BONE & JOINT DIS,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM.
Effect of salmon calcitonin on femoral bone quality in adult ovariectomized ewes (1996)
Boonen, S, Nijs, J, Jiang, Y, Lowet, G, VanAuderkercke, R, Huyghe, C, ...
The aim of this study was to evaluate the effect of intermittent calcitonin on femoral bone quality in adult ewes from the time of ovariectomy. Six months after the start of the experiment, bone...
Heterogeneity of bone loss and loss of muscle strength in elderly women. (1996)
GEUSENS, Piet, VANHOOF, Johan, MERTENS, Johan, RAUS, Jef
DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3590 DIEPENBEEK,BELGIUM.
Falls, benzodiazepines and fractures in post-menopausal women (1996)
Hemmer, P, Kegelaers, G, Autier, P, GEUSENS, Piet
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,LIMBURGERHOF,GERMANY.
Detection of women at risk for osteoporosis in general practice. (1996)
Coppens, E, Autier, P, GEUSENS, Piet, VANHOOF, Johan
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,B-3610 DIEPENBEEK,BELGIUM. INST JULES BORDET,BRUSSELS,BELGIUM.
GEUSENS, Piet, VANHOOF, Johan, VANDERVORST, Carine, RAUS, Jef, Vankrieken, L
DR WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,DIEPENBEEK,BELGIUM. DIAGNOST PROD CORP,LOS ANGELES,CA.
Devogelaer, JP, Broll, H, CorreaRotter, R, Cumming, DC, DeDeuxchaisnes, CN, Hosking, D, ...
To determine the effects of long-term daily oral alendronate sodium (ALN) on bone mass in postmenopausal women with osteoporosis, 19 centers enrolled 516 postmenopausal women aged 45-80 gears with...
FEASIBILITY OF A TRANSPORTABLE DEVICE TO MEASURE BONE-DENSITY IN PRIMARY-CARE SETTINGS (1995)
NIJS, J, DEQUEKER, J, GEUSENS, Piet, RAUS, Jef
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,B-3001 LOUVAIN,BELGIUM.
NANDROLONE DECANOATE - PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN OSTEOPOROSIS (1995)
The therapeutic profile on bone of nandrolone decanoate is that of inhibitor of bone resorption with temporary increase in bone formation, followed by an absence of suppression of bone formation,...
EFFECT OF PAMIDRONATE ON ANTIGEN-SPECIFIC AND NONSPECIFIC T-LYMPHOCYTE PROLIFERATION (1995)
CELIS, L, ZHANG, J, GEUSENS, Piet, RAUS, Jef
DR L WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3610 DIEPENBEEK,BELGIUM.
VANDEVYVER, C, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3610 DIEPENBEEK,BELGIUM.
PAUWELS, RA, DEMEDIS, MG, YERNAULT, JC, OLBRECHT, J, GEUSENS, Piet
DR WILLEMS INST,DIEPENBEEK,BELGIUM. STATE UNIV GHENT,B-9000 GHENT,BELGIUM. CATHOLIC UNIV LEUVEN,B-3000 LOUVAIN,BELGIUM. UNIV LIBRE BRUXELLES,B-1050 BRUSSELS,BELGIUM.
SPAEPEN, M, GU, XX, VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
UNIV LOUVAIN,CTR HUMAN GENET,LOUVAIN,BELGIUM. DR L WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,DIEPENBEEK,BELGIUM.
VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
The association of rheumatoid arthritis (RA) with HLA-DRB1 alleles indicates that at least one RA susceptibility gene is linked to the HLA class II region. Transporter associated with protein...
FEASIBILITY OF A TRANSPORTABLE DEVICE TO MEASURE BONE-DENSITY IN PRIMARY-CARE SETTINGS (1995)
NIJS, J, DEQUEKER, J, GEUSENS, Piet, RAUS, Jef
LIMBURGS UNIV CENTRUM,DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. KATHOLIEKE UNIV LEUVEN,B-3001 LOUVAIN,BELGIUM.
NANDROLONE DECANOATE - PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN OSTEOPOROSIS (1995)
The therapeutic profile on bone of nandrolone decanoate is that of inhibitor of bone resorption with temporary increase in bone formation, followed by an absence of suppression of bone formation,...
EFFECT OF PAMIDRONATE ON ANTIGEN-SPECIFIC AND NONSPECIFIC T-LYMPHOCYTE PROLIFERATION (1995)
CELIS, L, GEUSENS, Piet, RAUS, Jef, Zhang, JK
DR L WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3610 DIEPENBEEK,BELGIUM.
VANDEVYVER, C, GEUSENS, Piet, VANHOOF, Johan, RAUS, Jef
DR WILLEMS INST,B-3590 DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,B-3610 DIEPENBEEK,BELGIUM.
PAUWELS, RA, DEMEDIS, MG, YERNAULT, JC, OLBRECHT, J, GEUSENS, Piet
DR WILLEMS INST,DIEPENBEEK,BELGIUM. STATE UNIV GHENT,B-9000 GHENT,BELGIUM. CATHOLIC UNIV LEUVEN,B-3000 LOUVAIN,BELGIUM. UNIV LIBRE BRUXELLES,B-1050 BRUSSELS,BELGIUM.
SPAEPEN, M, GU, XX, VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
UNIV LOUVAIN,CTR HUMAN GENET,LOUVAIN,BELGIUM. DR L WILLEMS INST,DIEPENBEEK,BELGIUM. LIMBURGS UNIV CENTRUM,DIEPENBEEK,BELGIUM.
VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
The association of rheumatoid arthritis (RA) with HLA-DRB1 alleles indicates that at least one RA susceptibility gene is linked to the HLA class II region. Transporter associated with protein...
T-CELL RECEPTOR-DELTA LOCUS POLYMORPHISM IN RHEUMATOID-ARTHRITIS (1994)
VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
In order to identify new susceptibility markers for Rheumatoid Arthritis (RA), we analysed the dinucleotide repeat polymorphism at the T cell receptor delta locus (TCRD) in 65 RA patients and 99...
VANDEVYVER, C, GU, XX, SPAEPEN, M, CASSIMAN, JJ, GEUSENS, Piet, PHILIPPAERTS, Linda, ...
Objectives-To investigate whether T-cell receptor (TCR) beta chain germline alleles, either alone or in combination with a particular HLA-genotype, are associated with rheumatoid arthritis (RA)....
T-CELL RECEPTOR-DELTA LOCUS POLYMORPHISM IN RHEUMATOID-ARTHRITIS (1994)
VANDEVYVER, C, CASSIMAN, JJ, GEUSENS, Piet, RAUS, Jef
In order to identify new susceptibility markers for Rheumatoid Arthritis (RA), we analysed the dinucleotide repeat polymorphism at the T cell receptor delta locus (TCRD) in 65 RA patients and 99...
VANDEVYVER, C, GU, XX, SPAEPEN, M, CASSIMAN, JJ, GEUSENS, Piet, PHILIPPAERTS, Linda, ...
Objectives-To investigate whether T-cell receptor (TCR) beta chain germline alleles, either alone or in combination with a particular HLA-genotype, are associated with rheumatoid arthritis (RA)....
Linsen, Loes, Thewissen, Marielle, Baeten, Kurt, Somers, Veerle, Geusens, Piet, Raus, Jef, ...
Natural killer T (NKT) cells have been implicated in the regulatory immune mechanisms that control autoimmunity. However, their precise role in the pathogenesis of rheumatoid arthritis (RA) remains...
Linsen, Loes, Thewissen, Marielle, Baeten, Kurt, Somers, Veerle, Geusens, Piet, Raus, Jef, ...
Natural killer T (NKT) cells have been implicated in the regulatory immune mechanisms that control autoimmunity. However, their precise role in the pathogenesis of rheumatoid arthritis (RA) remains...
Heijckmann, A Caroline, Dumitrescu, Bianca, Nieuwenhuijzen Kruseman, Arie C, Geusens, Piet, Wolffenbuttel, Bruce HR, De Vries, Jolanda, ...
Faber, Birgit C.G., Rousch, Mat, Van Doorn, Ruben, Hackeng, Tilman M., Vink, Cornelis, ...
Novel biomarkers, such as circulating (auto)antibody signatures, may improve early detection and treatment of ruptured atherosclerotic lesions and accompanying cardiovascular events, such as...
Lumiracoxib is a COX2 inhibitor that is highly selective, is more effective than placebo on pain in osteoarthritis (OA), with similar analgesic and anti-inflammatory effects as non-selective NSAIDs...
Dumitrescu, Bianca, Van Helden, Svenjhalmar, Ten Broeke, Rene, Nieuwenhuijzen-Kruseman, Arie, Wyers, Caroline, Udrea, Gabriela, ...
The aetiology of osteoporotic fractures is multifactorial, but little is known about the way to evaluate patients with a recent clinical fracture for the presence of secondary osteoporosis.
Emerging treatments for postmenopausal osteoporosis – focus on denosumab
The pathway of the receptor activator of the nuclear factor κB ligand (RANKL), RANK and osteoprotegerin (OPG) plays a central role in coupling bone formation and resorption during normal bone...
Chung, P. Y. J., Beyens, G., Riches, P. L., Van Wesenbeeck, L., Jennes, K., Daroszewska, A., ...
[Chung, P. Y. J.; Beyens, G.; Van Wesenbeeck, L.; Jennes, K.; Van Hul, W.] Univ Antwerp, Dept Med Genet, B-2020 Antwerp, Belgium. [Chung, P. Y. J.; Beyens, G.; Van Wesenbeeck, L.; Jennes, K.; Van...
Spine radiographs to improve the identification of women at high risk for fractures
Netelenbos, J. C., Lems, W. F., GEUSENS, Piet, Verhaar, H. J., Boermans, A. J. M., Boomsma, M. M., ...
In women older than 60 years with clinical risk factors for osteoporosis but without osteoporosis based on bone mineral density (T-score a parts per thousand yenaEuro parts per thousand a'2.5), a...
Discovery of Novel Antigenic Targets and Autoantibody Markers in Rheumatoid Arthritis
SOMERS, Klaartje, GEUSENS, Piet, STINISSEN, Piet, SOMERS, Veerle
Hasselt Univ, Diepenbeek, Belgium. Transnatl Univ Limburg, Diepenbeek, Belgium.