Polymorphisms, Mutations, and Amplification of the EGFR Gene in Non-Small Cell Lung Cancers (2007)
Masaharu Nomura, Hisayuki Shigematsu, Lin Li, Makoto Suzuki, Takao Takahashi, Pila Estess, ...
BackgroundThe epidermal growth factor receptor (EGFR) gene is the prototype member of the type I receptor tyrosine kinase (TK) family and plays a pivotal role in cell proliferation and...
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
Siegelman, Mark H., Stanescu, Diana, Estess, Pila
Leukocytes extravasate from the blood in response to physiologic or pathologic demands by means of complementary ligand interactions between leukocytes and endothelial cells. The multistep model of...
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
Siegelman, Mark H., Stanescu, Diana, Estess, Pila
Leukocytes extravasate from the blood in response to physiologic or pathologic demands by means of complementary ligand interactions between leukocytes and endothelial cells. The multistep model of...
Polymorphisms, Mutations, and Amplification of the EGFR Gene in Non-Small Cell Lung Cancers
Nomura, Masaharu, Shigematsu, Hisayuki, Li, Lin, Suzuki, Makoto, Takahashi, Takao, Estess, Pila, ...
Masaharu Nomura and colleagues examine the distribution ofEGFR polymorphisms in different populations and find differences that might explain different responses to tyrosine kinase inhibitors in lung...
Firan, Mihail, Dhillon, Sohita, Estess, Pila, Siegelman, Mark H.
CD4CD25+ regulatory T cells are fundamental to the maintenance of peripheral tolerance and have great therapeutic potential. However, efforts in this regard have been hampered by limiting cell...
Estess, Pila, Nandi, Animesh, Mohamadzadeh, Mansour, Siegelman, Mark H.
T cell recruitment to extralymphoid tissues is fundamental to the initiation and perpetuation of the inflammatory state during immune and autoimmune responses. Interleukin (IL)-15 is a...
The Route of Antigen Entry Determines the Requirement for L-selectin during Immune Responses
Catalina, Michelle D., Carroll, Michael C., Arizpe, Helen, Takashima, Akira, Estess, Pila, Siegelman, Mark H.
L-selectin, an adhesion molecule constitutively expressed on leukocytes, is important for primary adhesion and extravasation of lymphocytes at specialized high endothelial venules within lymph nodes...