Pu P. Liu

Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia (2006)

Kuo, Ya-Huei, Landrette, Sean F., Heilman, Susan Ann, Perrat, Paola N., Garrett, Lisa, Liu, Pu P., ...

The acute myeloid leukemia (AML)-associated CBF beta-SMMHC fusion protein impairs hematopoietic differentiation and predisposes to leukemic transformation. The mechanism of leukemia progression,...

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia (2004)

Castilla, Lucio H., Perrat, Paola N., Martinez, Natalia J., Landrette, Sean F., Keys, R., Oikemus, Sarah R., ...

Acute myeloid leukemia subtype M4 with eosinophilia is associated with a chromosome 16 inversion that creates a fusion gene CBFB-MYH11. We have previously shown that CBFB-MYH11 is necessary but not...

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences

Henning, Karla A., Novotny, Elizabeth A., Compton, Sheila T., Guan, Xin-Yuan, Liu, Pu P., Ashlock, Melissa A.

A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (YAC) that was selected based on its size from among several YACs identified by screening a randomly...

Humanizing the yeast telomerase template

Henning, Karla A., Moskowitz, Naomi, Ashlock, Melissa A., Liu, Pu P.

Saccharomyces cerevisiae contains an irregular telomere sequence (TG1–3)n, which differs from the regular repeat (TTAGGG)n found at the telomeres of higher organisms including humans. We have...

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein ɛ-deficient mice

Yamanaka, Ryuya, Barlow, Carrolee, Lekstrom-Himes, Julie, Castilla, Lucio H., Liu, Pu P., Eckhaus, Michael, ...

Polymorphonuclear leukocytes are essential for host defense to infectious diseases. CCAAT/enhancer binding protein ɛ (C/EBPɛ) is preferentially expressed in granulocytes and lymphoid cells. Mice...

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences

Henning, Karla A., Novotny, Elizabeth A., Compton, Sheila T., Guan, Xin-Yuan, Liu, Pu P., Ashlock, Melissa A.

A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (YAC) that was selected based on its size from among several YACs identified by screening a randomly...

Humanizing the yeast telomerase template

Henning, Karla A., Moskowitz, Naomi, Ashlock, Melissa A., Liu, Pu P.

Saccharomyces cerevisiae contains an irregular telomere sequence (TG1–3)n, which differs from the regular repeat (TTAGGG)n found at the telomeres of higher organisms including humans. We have...

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein ɛ-deficient mice

Yamanaka, Ryuya, Barlow, Carrolee, Lekstrom-Himes, Julie, Castilla, Lucio H., Liu, Pu P., Eckhaus, Michael, ...

Polymorphonuclear leukocytes are essential for host defense to infectious diseases. CCAAT/enhancer binding protein ɛ (C/EBPɛ) is preferentially expressed in granulocytes and lymphoid cells. Mice...