Rüdiger Spitz

Featured Article The Tumor-Associated Antigen PRAME Is Universally Expressed in High-Stage Neuroblastoma and Associated with Poor Outcome (2008)

André Oberthuer, Barbara Hero, Rüdiger Spitz, Frank Berthold, Matthias Fischer

Purpose: The tumor-associated antigen PRAME, a potential candidate for immunotherapeutic targeting, is frequently expressed in a variety of cancers. However, no information about its presence in...

Gene-expression based classification of neuroblastoma patients using a customized oligonucleotide-microarray outperforms current clinical risk stratification (2006)

Oberthuer, André, Berthold, Frank, Warnat, Patrick, Hero, Barbara, Kahlert, Yvonne, Spitz, Rüdiger, ...

PURPOSE: To develop a gene expression–based classifier for neuroblastoma patients that reliably predicts courses of the disease. PATIENTS AND METHODS: Two hundred fifty-one neuroblastoma specimens...