R. A.

Non-Gaussianity in the Very Small Array cosmic microwave background maps with smooth goodness-of-fit tests (2006)

We have used the Rayner and Best smooth tests of goodness-of-fit to study the Gaussianity of the Very Small Array (VSA) data. These tests are designed to be sensitive to the presence of `smooth'...

O espaço público, a democracia e a participação na era da reprodutibilidade técnica (2005)

Trabalho apresentado na Sessão de Temas Livres durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005.  As...

Comunicação interna impulsionou produtividade da General Motors do Brasil (2005)

Trabalho apresentado na Sessão de Temas Livres durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005.  Na...

Jornalismo, Ensino e Pesquisa: As Contribuições do Professor Sebastião Jorge para a Construção da Trajetória da Mídia Impressa Maranhense . (2005)

  • PINHEIRO,
  • R.A

Trabalho apresentado no NP02 - Jornalismo durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005.  Este artigo traz...

O cinema e a construção do imaginário: as invenções da história (2005)

Trabalho apresentado no NP11 - Comunicação Educativa durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005....

O desemprego estrutural crônico: uma leitura através das charges (2005)

Trabalho apresentado no NP16 - Histórias em Quadrinhos durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005....

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage (2005)

STAT-1 plays a role in mediating stress responses to various stimuli and has also been implied to be a tumour suppressor. Here, we report that STAT-1-deficient cells have defects both in...

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study (2005)

  • Bukulmez,
  • H.,
  • Fife,
  • M.,
  • Tsoras,
  • M.,
  • ...

Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability. JRA is likely to be a complex genetic...

A combined defect in the biosynthesis of N- and O-glycans in patients with cutis laxa and neurological involvement: the biochemical characteristics (2005)

  • Wopereis,
  • S.,
  • Morava,
  • T.,
  • Grunewald,
  • S.,
  • ...

Based on our preliminary observation of abnormal glycosylation in a cutis laxa patient, nine cutis laxa, patients were analyzed for congenital defects of glycosylation (CDG). Isoelectric focusing of...

Neuroprotective effects of HSP70 overexpression after cerebral ischaemia-An MRI study (2005)

Heat shock proteins (HSPs) have been reported to increase cell survival in response to a wide range of cellular challenges. However, the role of HSP70 overexpression is still a matter of debate, with...

Patients with unsolved congenital disorders of glycosylation type II can be subdivided in six distinct biochemical groups (2005)

  • Wopereis,
  • S.,
  • Morava,
  • E.,
  • Grunewald,
  • S.,
  • ...

Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoelectric focusing (IEF) of plasma transferrin and apolipoprotein C-III (apoC-III). We hypothesized that IEF of transferrin...

Isolated unilateral tuberous sclerosis-associated renal cystic disease in a neonate (2005)

  • Weber,
  • M.A.,
  • Risdon,
  • R.A.,
  • Malone,
  • M.,
  • ...

We present a male infant with antenatally detected, focal, unilateral apparently isolated renal cystic disease with morphological features of renal involvement in tuberous sclerosis. Only one...

Epstein-Barr virus-associated lymphoproliferative disorder presenting as apparently isolated gastrointestinal lesions in childhood (2005)

  • Sebire,
  • N.J.,
  • Malone,
  • M.,
  • Risdon,
  • R.A.,
  • ...

We present an unusual case of post-transplant lymphoproliferative disorder (PTLD) presenting as apparently isolated gastrointestinal lesions in a pediatric renal transplant recipient. The multiple...

No association between Angiotensin Converting Enzyme (ACE) gene variation and endurance athlete status in Kenyans (2005)

  • Scott,
  • R.A.,
  • Moran,
  • C.,
  • Wilson,
  • R.H.,
  • ...

East African runners are continually successful in international distance running. The extent to which genetic factors influence this phenomenon is unknown. The insertion (I) rather than deletion (D)...

The achiasmia spectrum: congenitally reduced chiasmal decussation (2005)

AIM: To describe the clinical spectrum of achiasmia, a congenital disorder of reduced relative decussation at the optic chiasm. METHODS: A retrospective case note and patient review of nine children...

ATP Released via Gap Junction Hemichannels from the Pigment Epithelium Regulates Neural Retinal Progenitor Proliferation (2005)

  • Pearson,
  • R.A.,
  • Dale,
  • N.,
  • Llaudet,
  • E.,
  • ...

The retinal pigment epithelium (RPE) plays an essential role in the normal development of the underlying neural retina, but the mechanisms by which this regulation occurs are largely unknown. Ca(2+)...

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells (2005)

During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G(1) and G(2) of the cell cycle, progenitor cell nuclei migrate back-and- forth across...

Heterozygous mutations of OTX2 cause severe ocular malformations (2005)

Major malformations of the human eye, including microphthalmia and anophthalmia, are examples of phenotypes that recur in families yet often show no clear Mendelian inheritance pattern. Defining loci...

HIV-1 incorporates ABO histo-blood group antigens that sensitise virions to complement-mediated inactivation (2005)

  • Neil,
  • S.J.,
  • McKnight,
  • A.,
  • Gustafsson,
  • K.,
  • ...

ABO histo-blood group antigens have been postulated to modify pathogen spread through the action of natural antibodies and complement. The antigens are generated by a polymorphic glycosyltransferase...

Cardioprotection mediated by urocortin is dependent upon PKCF epsilon activation (2005)

  • Lawrence,
  • K.M.,
  • Kabir,
  • A.M.N.,
  • Bellahcene,
  • M.,
  • ...

Urocortin (Ucn) is an endogenous cardioprotective agent that protects against the damaging effects of ischemia and reperfusion injury in vitro and in vivo. We have found that the mechanism of action...

L-carnitine and exercise tolerance in medium-chain acyl- coenzyme A dehydrogenase (MCAD) deficiency: A pilot study (2005)

Skeletal muscle function may be impaired in patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, but the value of L-carnitine in their long-term management is not clear. This study...

De Novo Uroplakin IIIa heterozygous mutations cause human renal adysplasia leading to severe kidney failure (2005)

  • Jenkins,
  • D.,
  • Bitner-Glindzicz,
  • M.,
  • Malcolm,
  • S.,
  • ...

Human renal adysplasia usually occurs sporadically, and bilateral disease is the most common cause of childhood end- stage renal failure, a condition that is lethal without intervention using...

Molecular and clinical analyses of Greig cephalopolysyndactyly and Pallister-Hall syndromes: robust phenotype prediction from the type and position of GLI3 mutations (2005)

  • Johnston,
  • J.J.,
  • Olivos-Glander,
  • I.,
  • Killoran,
  • C.,
  • ...

Mutations in the GLI3 zinc-finger transcription factor gene cause Greig cephalopolysyndactyly syndrome (GCPS) and Pallister-Hall syndrome (PHS), which are variable but distinct clinical entities. We...

Portrait of editorial board member - Gerry Melino (2005)

  • Knight,
  • R.A.,
  • Annicchiarico-Petruzzelli,
  • M.

Clinical and genetic spectrum of pyruvate dehydrogenase deficiency: Dihydrolipoamide acetyltransferase (E2) deficiency (2005)

  • HEad,
  • R.A.,
  • Brown,
  • R.M.,
  • Zolkipli,
  • Z,
  • ...

Pyruvate dehydrogenase deficiency is a major cause of primary lactic acidosis and neurological dysfunction in infancy and early childhood. Most cases are caused by mutations in the X-linked gene for...

Interstitial deletion of the long arm of chromosome 5 in a boy with multiple congenital anomalies and mental retardation: Molecular characterization of the deleted region to 5q22.3q23.3 (2005)

  • Garcia-Minaur,
  • S.,
  • Ramsay,
  • J.,
  • Grace,
  • E.,
  • ...

Interstitial deletions of the middle portion of the long arm of chromosome 5 are relatively rare. So far, only 36 cases have been reported. Because of the repetitive banding pattern of this region,...

Childhood thin GBM disease: review of 22 children with family studies and long-term follow-up (2005)

Thin glomerular basement membrane (GBM) disease is generally known to have a good renal prognosis, although renal insufficiency has sometimes been reported and the overlap with Alport syndrome...

Eye movement instabilities and nystagmus can be predicted by a nonlinear dynamics model of the saccadic system (2005)

The study of eye movements and oculomotor disorders has, for four decades, greatly benefitted from the application of control theoretic concepts. This paper is an example of a complementary approach...

A comparison of a similarity-based and a feature-based 2-D-3-D registration method for neurointerventional use (2005)

  • McLaughlin,
  • R.A.,
  • Hipwell,
  • J.,
  • Hawkes,
  • D.J.,
  • ...

Two-dimensional (2-D)-to-three-dimensional (3-D) registration can improve visualization which may aid minimally invasive neurointerventions. Using clinical and phantom studies, two state-of-the-art...

Fetal Gallstones. (2005)

  • Munjuluri,
  • N.,
  • Elgharaby,
  • N.,
  • Acolet,
  • D.,
  • ...

Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix (2005)

  • Guo,
  • L.,
  • Moss,
  • S.E.,
  • Alexander,
  • R.A.,
  • ...

PURPOSE: To investigate the effect of IOP on retinal ganglion cell (RGC) apoptosis and correlate the effects with IOP-induced changes in extracellular matrix (ECM) in the retina and optic nerve head...

Rapid assessment of microbial hazards in metalworking fluids (2005)

  • Webster,
  • A.R.,
  • Lee,
  • J.,
  • Deininger,
  • R.A.

Industries that use metalworking fluids require a test method that can rapidly estimate the total number of bacteria. Such a test method would improve the ability to manage the metal working fluid by...

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene (2005)

  • Aung,
  • T.,
  • Rezaie,
  • T.,
  • Okada,
  • K.,
  • ...

PURPOSE: To investigate the clinical features of subjects with glaucoma with the E50K mutation in the optineurin (OPTN) gene and to compare the onset, severity, and clinical course of these patients...

Cosmic microwave background observations from the Cosmic Background Imager and Very Small Array: a comparison of coincident maps and parameter estimation methods (2005)

  • Rajguru,
  • N.,
  • Myers,
  • S.T.,
  • Battye,
  • R.A.,
  • ...

WWe present coincident observations of the cosmic microwave background (CMB) from the Very Small Array (VSA) and Cosmic Background Imager (CBI) telescopes. The consistency of the full data sets is...

Determination of the infection densities of mudfish Eustrongylides   in Clarias gariepinus   and C. anguillaris from Bida floodplain of Nigeria (2004)

The infection densities of Eustrongylides africanus   larvae were analysed according to the season, sex and distribution. Its prevalence, intensity and abundance was 26.5 ± 15.4%, 2.1 ± 0.9 and...

Full Length Research Paper - Functional properties of amylopectin and amylose fractions isolated from bambarra groundnut (Voandzeia subterranean   ) starch (2004)

Bambarra groundnut starch was fractionated into amylose and amylopectin fractions, and chemical modifications, through oxidation and acetylation, was applied to the amylose fraction. Percentage yield...

STAT-1 interacts with p53 to enhance DNA-damage induced apoptosis (2004)

The STAT-1 transcription factor has been implicated as a tumor suppressor by virtue of its ability to inhibit cell growth and promoting apoptosis. However, the mechanisms by which STAT-1 mediates...

A quantitative description of lens eye morphology and its implications (2004)

Abstract If it is assumed that the differences between eyes constitute adaptations to different visual environments, then it should be possible to identify the visual environments for which the eye...

Cosmological parameter estimation using Very Small Array data out to l= 1500 (2004)

  • Rebolo,
  • R.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We estimate cosmological parameters using data obtained by the Very Small Array (VSA) in its extended configuration, in conjunction with a variety of other cosmic microwave background (CMB) data and...

Estimating the bispectrum of the Very Small Array data (2004)

  • Smith,
  • S.,
  • Rocha,
  • G.,
  • Challinor,
  • A.,
  • ...

We estimate the bispectrum of the Very Small Array data from the compact and extended configuration observations released in 2002 December, and compare our results with those obtained from Gaussian...

High-sensitivity measurements of the cosmic microwave background power spectrum with the extended Very Small Array (2004)

  • Dickinson,
  • C.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We present deep Ka-band (ν~ 33 GHz) observations of the cosmic microwave background (CMB) made with the extended Very Small Array (VSA). This configuration produces a naturally weighted...

Searching for non-Gaussianity in the Very Small Array data (2004)

  • Savage,
  • R.,
  • Battye,
  • R.A.,
  • Carreira,
  • P.,
  • ...

We have tested Very Small Array (VSA) observations of three regions of sky for the presence of non-Gaussianity, using high-order cumulants, Minkowski functionals, a wavelet-based test and a Bayesian...

Intensity-based 2-D-3-D registration of cerebral angiograms (2003)

We propose a new method for aligning three-dimensional (3-D) magnetic resonance angiography (MRA) with 2-D X-ray digital subtraction angiograms (DSA). Our method is developed from our algorithm to...

Medical Implications of Biofilms (2003)

  • An,
  • Y.H.,
  • Bhagwat,
  • S.,
  • Bokranz,
  • W.,
  • ...

Mathematical models of eye movements (2003)

  • Akman,
  • O.,
  • Broomhead,
  • D.S.,
  • Clement,
  • R.A.

Short communication - A COMPARATIVE STUDY OF SOME HEMATOLOGY AND BIOCHEMICAL PARAMETERS OF CLINICALLY HEALTHY ALSATIAN AND LOCAL DOGS (2002)

The effect of breed on serum biochemistry and hematological parameters of clinically healthy dogs was studied by collecting blood from the cephalic vein of ten (10) Alsatian and ten (10) local dogs....

Ocular developmental abnormalities and glaucoma associated with interstitial 6p25 duplications and deletions (2002)

  • Lehmann,
  • O.J.,
  • Ebenezer,
  • N.D.,
  • Ekong,
  • R.,
  • ...

PURPOSE: Mutations in the forkhead transcription factor gene FOXC1 on 6p25 cause a range of ocular developmental abnormalities, with associated glaucoma. However, FOXC1 mutations have not been found...

DDAVP nasal spray for treatment of menorrhagia in women with inherited bleeding disorders: a randomized placebo-controlled crossover study (2002)

To assess DDAVP (1-deamino-8-D-arginine vasopressin; desmopressin) nasal spray in the management of menorrhagia in patients with inherited bleeding disorders, 39 women (aged 1850 years) with...

Progress with FOXC1 gene dosage (2001)

  • Lehman,
  • O.J.,
  • Jordan,
  • T.L.,
  • Ebenezer,
  • N.,
  • ...

Rectification of cGMP-activated channels induced by phosphorylation in dogfish retinal 'on' bipolar cells (2001)

  • Shiells,
  • R.A.,
  • Falk,
  • G.

1. Whole-cell current responses to brief flashes were obtained from voltage-clamped 'on' bipolar cells in dark-adapted dogfish retinal slices. When internal Ca2+ was buffered to low levels, the...

Evidence for nonspecific adsorption of targeted retrovirus vector particles to cells (2001)

  • Pizzato,
  • M.,
  • Blair,
  • E.D.,
  • Fling,
  • M.,
  • ...

The ability to specifically target a cell-type is important for the development of vectors for in vivo gene therapy. In order to produce retrovirus vectors targeting ovarian cancer cells, which...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

Multiple groups of novel retroviral genomes in pigs and related species (2001)

  • Patience,
  • C.,
  • Switzer,
  • W.M.,
  • Takeuchi,
  • Y.,
  • ...

In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...

MuLV packaging systems as models for estimating/measuring retrovirus recombination frequency (2001)

  • Patience,
  • C.,
  • Takeuchi,
  • Y.,
  • Cosset,
  • F.L.,
  • ...

Interaction of retrovirus vectors and endogenous retroviruses present in packaging cell lines and target cells may result in the formation of recombinant viruses. Using sensitive RT-PCR assays, we...

Susceptibility of the porcine endogenous retrovirus to reverse transcriptase and protease inhibitors (2001)

  • Qari,
  • S.H.,
  • Magre,
  • S.,
  • Garcia-Lerma,
  • J.G.,
  • ...

Porcine xenografts may offer a solution to the shortage of human donor allografts. However, all pigs contain the porcine endogenous retrovirus (PERV), raising concerns regarding the transmission of...

Detection of antibodies to human herpesvirus 8 in Italian children: evidence for horizontal transmission (2000)

  • Whitby,
  • D.,
  • Luppi,
  • M.,
  • Sabin,
  • C.,
  • ...

Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma associated herpesvirus (KSHV), has been shown to be the causative agent for Kaposi's sarcoma (KS) and to be more prevalent in populations...

Reproductive choices of women in families with haemophilia (2000)

  • Kadir,
  • R.A.,
  • Sabin,
  • C.A.,
  • Goldman,
  • E.,
  • ...

To assess women's experiences in pregnancy and attitudes towards their reproductive choices, a structured questionnaire was sent to all obligate and potential carriers of haemophilia (A and B), aged...

HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma (2000)

  • Dupin,
  • N.,
  • Diss,
  • T.L.,
  • Kellam,
  • P.,
  • ...

Castleman disease (CD) is a lymphoproliferative disorder of unknown etiology that is associated with the development of secondary tumors, including B-cell lymphoma. Human herpesvirus 8 (HHV-8)...

Obstetrical and gynaecological bleeding: a common presenting symptom (2000)

Excessive haemorrhage is one of the commonest symptom when women present to obstetricians and gynaecologists. In the majority of cases the cause is related to the primary obstetric and gynaecological...

Ultrasonographic markers for chromosomal abnormalities in women with negative nuchal translucency and second trimester maternal serum biochemistry (2000)

  • Verdin,
  • S.M.,
  • Whitlow,
  • B.J.,
  • Lazanakis,
  • M.,
  • ...

OBJECTIVE: To analyze the value of second trimester ultrasound examination among those women whose fetuses were indicated to be at low risk of chromosomal anomalies on the basis of both first...

Assessment of menstrual blood loss and gynaecological problems in patients with inherited bleeding disorders (1999)

Summary:- Menstral blood loss and gynaecological problems in aptients with inherited bleeding disorders were assessed in this study. One hundred and sixteen women, including 66 with Willebrand's...

Quantitative 99mTc-DMSA uptake in experimental pyelonephritis (1999)

  • Godley,
  • M.L.,
  • Risdon,
  • R.A.,
  • Gordon,
  • I.,
  • ...

Quantitative 99mTc-dimercaptosuccinic acid (DMSA) renal uptake was studied in unilateral reflux-related pyelonephritis in pigs. The changes to absolute % dose uptake and differential uptake occurring...

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma (1999)

  • Dupin,
  • N.,
  • Fisher,
  • C.,
  • Kellam,
  • P.,
  • ...

Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi's sarcoma (KS), multicentric Castleman's disease (MCD), and primary effusion lymphoma (PEL). The universal...

Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8 (1999)

  • Kellam,
  • P.,
  • Bourboulia,
  • D.,
  • Dupin,
  • N.,
  • ...

Human herpesvirus 8 (HHV-8; also designated Kaposi's sarcoma-associated herpesvirus) is the likely etiological agent of Kaposi's sarcoma (KS). HHV-8 encodes a latent nuclear antigen (LNA) which is...

Frequency of inherited bleeding disorders in women with menorrhagia (1998)

BACKGROUND: Although menorrhagia is a common gynaecological symptom, a specific cause is identified in less than 50% of affected women. We investigated the frequency of inherited bleeding disorders...

Pregnancy in women with von Willebrand's disease or factor XI deficiency (1998)

OBJECTIVE: To assess the obstetric outcome in women with von Willebrand's disease or factor XI deficiency. SETTING: Haemophilia Centre and Haemostasis Unit, The Royal Free Hospital. POPULATION: Women...

Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group (1998)

A recent report has provided strong evidence for a major prostate cancer susceptibility locus (HPC1) on chromosome 1q24-25 (Smith et al, 1996). Most inherited cancer susceptibility genes function as...

Human herpesvirus-8 and Kaposi's sarcoma (1998)

  • Weiss,
  • R.A.,
  • Whitby,
  • D.,
  • Talbot,
  • S.,
  • ...

Serum S-100 protein, relationship to clinical outcome in acute stroke (1997)

The clinical significance of serum S-100 protein, a protein released by damaged brain tissue, was assessed in patients with acute ischaemic or haemorrhagic stroke and matched controls. Serum S-100...

Omission of nitrous oxide during anesthesia reduces the incidence of postoperative nausea and vomiting: a meta-analysis (1996)

Background: Postoperative nausea and vomiting are important causes of morbidity after general anesthesia. Nitrous oxide has been implicated as an emetogenic agent in many studies. However, several...

An analysis of the verbal interaction of small group discussion members in secondary, social studies classes /--by R. A. Pendergrass. (1973)

Photocopy of typescript. Ann Arbor, Mich. : University Microfilms International, 1979. -- 21 cm.

 
Additional Information

Publishing period:

1939 - 2006 (217)

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