High-resolution Fourier domain optical coherence microscopy (2008)
Leitgeb, R. A., Steinmann, L., Imboden, C., Villiger, M., Leutenegger, M., Bachmann, A. H., ...
Highly confined depth focus for Fourier domain optical coherence microscopy (2008)
Leitgeb, R. A., Steinmann, L., Imboden, C., Villiger, M., Leutenegger, M., Bachmann, A. H., ...
Leitgeb, R. A., Michaely, R., Lasser, T., Sekhar, S. C.
We introduce a simple and cheap method for phase-shifting Fourier domain optical coherence tomography (FDOCT) that does not need additional devices and can easily be implemented. A small beam offset...
Fernandez, E. J., Povazay, B., Hermann, B., Unterhuber, A., Sattmann, H., Prieto, P. M., ...
Three-dimensional ultrahigh resolution optical coherence tomography (UHR OCT) and adaptive optics (AO) are combined using a liquid crystal programmable phase modulator (PPM) as a correcting device...
Optical Investigation of Skin Morphology and Anatomy (2008)
Michaely, R., Serov, A., Leitgeb, R. A., Jacquot, P., Lasser, T.
Fourier Domain Optical Coherence Microscopy with extended depth of field (2008)
Villiger, M., Bachmann, A. H., Leutenegger, M., Steinmann, L., Lasser, T., Leitgeb, R. A.
Complex unltrahigh resolution Fourier domain optical coherence tomography (2008)
Bachmann, A. H., Lasser, T., Leitgeb, R. A.
Fourier domain optical coherence tomography (FDOCT) is a high speed imaging technique with high axial resolution in the micro-meter-scale range combined with a high sensitivity allowing to probe 3D...
k-Microscopy: resolution beyond the diffraction limit (2008)
Leitgeb, R. A., Geissbühler, M., Lasser, T.
We introduce a novel microscopy method of probing the spatial frequencies of a two dimensional sample with a single point detector allowing for sub-micron resolution with low NA lenses as well as for...
Enhancement of extended depth of field by digital focusing (2008)
Villiger, M. L., Blatter, C., Lasser, T., Leitgeb, R. A.
With the use of a Bessel-like illumination beam produced by an axicon lens an extended depth of field can be achieved. The resulting illumination pattern exhibits a strong central lobe extending over...
Leitgeb, R. A., Michaely, R., Bachmann, A. H., Villiger, M. L., Blatter, C., Lasser, T.
We demonstrate a simple and cheap method for phase shifting that does not need additional devices. A small beam offset at the fast scanning mirror introduces a causal phase shift which can be used...
Extended focus Fourier domain optical coherence microscopy and fluorescence lifetime imaging (2008)
Villiger, M. L., Blatter, C., Bachmann, A. H., Lasser, T., Leitgeb, R. A.
Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel...
Extended focus optical coherence microscopy and fluorescence lifetime imaging (2008)
Villiger, M. L., Blatter, C., Bachmann, A. H., Lasser, T., Leitgeb, R. A.
Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel...
Fast focus field calculations (2008)
Leutenegger, M., Geissbühler, M., Märki, I., Leitgeb, R. A., Lasser, T.
We present a method for fast calculation of the electromagnetic field near the focus of an objective with a high numerical aperture (NA). Instead of direct integration, the vectorial Debye...
k-Microscopy: resolution beyond the diffraction limit (2008)
Geissbühler, M., Lasser, T., Leitgeb, R. A.
We present a novel Fourier domain method for microscopic imaging - so-called k-microscopy - with lateral resolution independent of the detection numerical aperture. The concept is based on sample...
Fast focus field calculations (2008)
Leutenegger, M., Geissbühler, M., Märki, I., Leitgeb, R. A., Lasser, T.
We present a method for fast calculation of the electromagnetic field near the focus of an objective with a high numerical aperture (NA). Instead of direct integration, the vectorial Debye...
Towards in vivo small animal imaging (2008)
Villiger, M. L., Goulley, J., Grapin-Botton, A., Friedrich, M., Meda, P., Lasser, T., ...
Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel...
Measurement of retinal physiology using functional Fourier domain OCT concepts (2008)
Leitgeb, R. A., Bachmann, A. H., Villiger, M. L., Michaely, R., Blatter, C., Pache, C., ...
Fourier Domain OCT proved to be an outstanding tool for measuring 3D retinal structures with high sensitivity, resolution, and speed. We extended the FDOCT concept towards functional imaging by...
Fast focus field calculations (2008)
Leutenegger, M., Rao, R., Leitgeb, R. A., Lasser, T.
We present a fast calculation of the electromagnetic field near the focus of an objective with a high numerical aperture (NA). Instead of direct integration, the vectorial Debye diffraction integral...
Extended focus depth for Fourier domain optical coherence microscopy (2008)
Leitgeb, R. A., Villiger, M., Bachmann, A. H., Steinmann, L., Lasser, T.
We report on a new detection scheme for Fourier domain optical coherence microscopy that exhibits high transverse resolution along an axially extended focal range. Nearly constant transverse...
Resonant Doppler flow imaging and optical vivisection of retinal blood vessels (2008)
Bachmann, A. H., Villiger, M. L., Blatter, C., Lasser, T., Leitgeb, R. A.
For Fourier domain optical coherence tomography any sample movement during camera integration causes blurring of interference fringes and as such reduction of sensitivity for flow detection. The...
Tumlinson, A. R., Barton, J. K., Povazay, B., Sattman, H., Unterhuber, A., Leitgeb, R. A., ...
Frequency domain optical coherence tomography (FD-OCT) allows interferometer topologies with simplified system construction and handling. Problems of dispersion and polarization matching between the...
Dual-beam heterodyne Fourier domain optical coherence tomography (2008)
Bachmann, A. H., Michaely, R., Lasser, T., Leitgeb, R. A.
We report on a novel method combining achromatic complex FDOCT signal reconstruction with a common path and dual beam configuration. The complex signal reconstruction allows resolving the complex...
Michaely, R., Bachmann, A. H., Villiger, M. L., Blatter, C., Lasser, T., Leitgeb, R. A.
Resonant Doppler Fourier domain optical coherence tomography (FDOCT) is a functional imaging tool for extracting tissue flow. The method is based on the effect of interference fringe blurring in...
Leitgeb, R. A., Michaely, R., Lasser, T., Sekhar, S. C.
We introduce a simple and cheap method for phase-shifting Fourier domain optical coherence tomography (FDOCT) that does not need additional devices and can easily be implemented. A small beam offset...
Leitgeb, R. A., Michaely, R., Bachmann, A. H., Villiger, M., Blatter, C., Lasser, T.
PURPOSE: To perform high speed and completely non-invasive 3D angiography at the optic nerve head region and to reconstruct vectorial 3D blood flow from optically segmented blood vessel structure as...
Rao, R., Mitic, J., Serov, A., Leitgeb, R. A., Lasser, T.
The solid immersion lens (SIL) as a tool for increasing the field confinement as well as providing optimal performance by aberration compensation in a confocal fluorescence correlation spectroscopy...
Image formation in fluorescence coherence-gated imaging through scattering media (2008)
Bilenca, A., Lasser, T., Ozcan, A., Leitgeb, R. A., Bouma, B. E., Tearney, G. J.
Recently, we have experimentally demonstrated a new form of cross-sectional, coherence-gated fluorescence imaging referred to as SD-FCT (‘spectral-domain fluorescence coherence tomography’)....
High speed full range complex spectral domain optical coherence tomography (2006)
Götzinger, E., Pircher, M., Leitgeb, R. A., Hitzenberger, C. K.
We present a high speed full range spectral domain optical coherence tomography system. By inserting a phase modulator into the reference arm and recording of every other spectrum with a 90° phase...
Parallel Fourier domain optical coherence tomography for in vivo measurement of the human eye (2006)
Grajciar, B., Pircher, M., Fercher, A. F., Leitgeb, R. A.
A parallel Frequency Domain Optical Coherence Tomography (FD-OCT) system and - to the best of our knowledge- first in vivo tomograms obtained with such system are presented. A full tomogram of 256(x)...
Bachmann, A. H., Leitgeb, R. A., Lasser, T.
One of the main drawbacks of Fourier domain optical coherence tomography (FDOCT) is the limited measurement depth range. Phase shifting techniques allow reconstructing the complex sample signal...
Dual-color total internal reflection fluorescence cross- correlation spectroscopy (2006)
Leutenegger, M., Blom, H., Widengren, J., Eggeling, C., Gösch, M., Leitgeb, R.A., ...
We present the development and first application of a novel dual-color total internal reflection (TIR) fluorescence system for single-molecule coincidence analysis and fluorescence cross-correlation...