R. A. Miller

Publication List Details

Period

1943 - 2008

Number

161

Co-Authors

GC-PFAIMS as Smart Smoke Alarm. Identification of Combustion Sources by Patterns of Retention Time and Compensation Voltage (2008)

G. A. Eiceman, A. Tarassov, P. Funk, R. A. Miller, E. G. Nazarov, E. Hughes

Adapted from a lengthy manuscript submitted for publication. Smoke alarms are based commonly upon principles of light deflection by particles or interruption of current flow between a radioactive ion...

A FOOD REFRIGERATION AND HABITABLE ATMOSPHERE CONTROL SYSTEM FOR SPACE VEHICLES, DESIGN, FABRICATION, AND TEST PHASES. (2006)

Miller,R.A., Halpert,S.

The purpose of this development project was to design, fabricate, and evaluate a food refrigera tion and habitable atmosphere control system which will support a three-man crew for an extreme alti...

On exemplary scientific conduct regarding submission of manuscripts to biomedical informatics journals (2006)

Miller, R.A., Groth, T., Hasman, A., Safran, C., Shortliffe, E.H., Haux, R., ...

As the Editors of leading international biomedical informatics journals, the authors report on a recent pattern of improper manuscript submissions to journals in our field. As a guide for future...

SHEAR STRENGTHS ON MATERIALS-ALUMINUM ALLOY-X2020-T6 (2005)

MILLER,R.A., STEURER,W.H.

Simple shear tests made with 1/8-inch diameter X2020 wire indicated the following shear strengths occurrences in various wire conditions: as received, 25,070 psi; annealed (775 F, 1 hour, slow cool...

Facility Intrusion Detection System, (2005)

Barker,B., Miller,R. A.

The Facility Intrusion Detection System will provide physical security protection for Department of Defense (DOD) facilities containing sensitive items that may be prime targets of organized criminal...

Embryogenesis and Production of Albino Plants from Cell Cultures of 'Bromus inermis', (2005)

Gamborg,Oluf L., Constabel,F., Miller,R. A.

Embryogenesis occurs in cells from brome grass grown in suspension culture in defined medium. Exogenous hormones are not required. The embryos develop into plants which lack chlorophyll. (Author)

EMERGENCY BREATHING AND SUIT PRESSURIZATION SYSTEM. (2005)

MILLER,R. A., Withey,D. J.

The design and fabrication of an Emergency Breathing and Suit Pressurization System (EBSPS), capable of sustaining three full-pressure suited crewmen within the Aerospace Medical Research...

High power microwaves - measures and countermeasures (2004)

Kashyap, S., Mende, H., Palisek, L., Krogager, E., Chevalier, B., Römer, B., ...

The technological development within the area of High Power Microwaves (HPM) has made it possible to produce more and more powerful microwave sources for large operational installations, but at the...

Toxicology Studies on Lewisite and Sulfur Mustard Agents: Two-Generation Reproduction Study of Sulfur Mustard (HD) in Rats (2003)

Sasser, L. B., Miller, R. A., Kalkwarf, D. R., Buschbom, R. L., Cushing, J. A.

Chemical warfare agents present an obvious risk to individuals suffering acute exposure, but they may also present long-term environmental or occupational health hazards for workers in operations...

Carcinogenicity of Inhaled Vanadium Pentoxide in F344/N Rats and B6C3F1 Mice (2003)

Ress, N.B., Chou, B.J., Renne, R.A., Dill, J.A., Miller, R.A., Roycroft, J.H., ...

Vanadium pentoxide (V2O5) is a slightly soluble compound found in airborne particle emissions from metallurgical works, and oil and coal burning. Because the carcinogenic potential of V2O5 was not...

Carcinogenicity of Inhaled Vanadium Pentoxide in F344/N Rats and B6C3F1 Mice (2003)

Ress, N. B., Chou, B. J., Renne, R. A., Dill, J. A., Miller, R. A., Roycroft, J. H., ...

Vanadium pentoxide (V2O5) is a slightly soluble compound found in airborne particle emissions from metallurgical works and oil and coal burning. Because the carcinogenic potential of V2O5 was not...

Carcinogenicity of Inhaled Vanadium Pentoxide in F344/N Rats and B6C3F1 Mice (2003)

Ress, N.B., Chou, B.J., Renne, R.A., Dill, J.A., Miller, R.A., Roycroft, J.H., ...

Vanadium pentoxide (V2O5) is a slightly soluble compound found in airborne particle emissions from metallurgical works, and oil and coal burning. Because the carcinogenic potential of V2O5 was not...

Research and Development on Ultra-Light-Weight Low-Loss Optical Fiber Communication Cable. (2002)

Frazier,J. F., Miller,R. A.

An ultra-lightweight, low-loss optical waveguide communication cable was developed for tactical field army applications. The cable which resulted from this work was an all-dielectric structure, 5 mm...

Reaction of Human Sera with Eubacterium brachy: Isolation and Characterization of an Extracellular Antigen, (2002)

Vincent,J. W., Delessandro,N. F., Miller,R. A.

Recent studies have demonstrated an association of Eubacterium sp. with the subgingival microflora of patients with chronic periodontitis. One species, Eubacterium brachy, was evaluated to determine...

A SPACE TRAJECTORY RADIATION EXPOSURE PROCEDURE FOR CISLUNAR MISSIONS (1998)

CRANFORD,W., FALKENBURY,R.F., MILLER,R.A.

The Space Trajectory Radiation Exposure Procedure (STREP) is designed to compute the time-integrated spectra for any specified trajectory in cislunar space for any combination of the several...

PLANT PROTOPLASTS FOR USE IN SOMATIC CELL HYBRIDIZATION, (1998)

Keller,W. A., Harvey,B., Gamborg,O. L., Miller,R. A., Eveleigh,D. E.

Somatic cell hybridization is a potentially useful technique for the introduction of genetic variability into plant species. One proposed method involves fusion of plant protoplasts (which is a cell...

Optimization of Optical Waveguides Strength Studies. (1998)

Maurer,R. D., Miller,R. A., Smith,D. D., Trondsen,J. C.

A tensile test and testing procedures were developed and used to evaluate the effects of lubricants, coatings and reeling conditions on glass fiber strength. The results indicated that fiber failure...

Research and Development on Ultra-Lightweight Low-Loss Optical Fiber Communication Cable. (1998)

Frazier, J. F., Miller, R. A.

This interim report describes the initial phases of the investi-gation to provide ultra-lightweight, low-loss optical fiber communication cables for tactical field army environments. Initial efforts...

Effect of Alloying, Rapid Solidification, and Surface Kinetics on the High Temperature Environmental Resistance of Niobium. (1998)

Perkins, R. A., Meier, G. H., Miller, R. A., Chiang, K. T.

An improved understanding of factors governing the selective oxidation of aluminum to form continuous alumina scales on modified niobium-aluminum alloys has been established. It has been demonstrated...

Effect of Alloying, Rapid Solidification, and Surface Kinetics on the High Temperature Environmental Resistance of Niobium. (1998)

Perkins, R. A., Chiang, K. T., Meier, G. H., Miller, R. A.

Factors affecting the formation of protective alumina scales on niobium-base alloys by selective oxidation have been investigated. Alumina cannot be formed in air at latm. on binary Nb-A1 alloys at...

Compressive Strength of Duralumin Channels. Air Service Information Circular, Volume 6, Number 598 (1998)

Miller, R. A.

Historical study that records the results of tests to determine the compressive strength of duralumin channels, to recommend methods for their design and to show the application of these methods to...

Life Modeling of Thermal Barrier Coatings for Aircraft Gas Turbine Engines. (1998)

Miller, R. A.

Thermal barrier coatings are being developed for protecting air-cooled turbine blades and vanes in aircraft gas turbine engines. The benefits arise from the insulation provided by the ceramic layer....

Lung Tumor Induction by Inhalation Exposure to Molybdenum Trioxide in Rats and Mice (1998)

Chan, P. C., Herbert, R. A., Roycroft, J. H., Haseman, J. K., Grumbein, S. L., Miller, R. A., ...

Inhalation studies of molybdenum trioxide (MoO3) were conducted because of its wide use in industry, human exposure, and lack of data on carcinogenicity. Groups of 50 male and 50 female F344/N...

Carcinogenesis Studies of Tetrahydrofuran Vapors in Rats and Mice (1998)

Chhabra, R. S., Herbert, R. A., Roycroft, J. H., Chou, B., Miller, R. A., Renne, R. A.

Tetrahydrofuran (THF) is a widely used industrial solvent and was selected for carcinogenesis studies by the National Toxicology Program (NTP) because of its potential for widespread occupational...

A Visualization Tool For Mechanical Design (1996)

S. C. Lu, Lu Rebello, D. H. Cui, R. Yagel, R. A. Miller, G. L. Kinzel

In this paper, we present a new visualization approach to support Design For Manufacturing (DFM). This involves the correlation of manufacturing problems with the causative geometric characteristics....

Volume-Based Reasoning and Visualization of Diecastability (1995)

Yagel Lu, S. C. Lu, A. B. Rebello, R. A. Miller

Because of the nature of the die casting process, the part geometry severely restricts the die geometry and hence affects the quality of the part. However, as is often the case in other manufacturing...

Nonlinear Finite Element Analysis of Deteriorated RC Slab Bridge (1994)

Sharooz, B.M., Ho, I.K., Aktan, A.E., De Borst, R., Blaauwendraad, J., ...

Applications of nonlinear finite element analysis (NLFEA) to complete structures have been limited. The study reported in this paper examined the reliability of NLFEA to assess strength and stiffness...

Subchronic Toxicity of Tetrahydrofuran Vapors in Rats and Mice (1990)

CHHABRA, R. S., ELWELL, M. R., CHOU, B., MILLER, R. A., RENNE, R. A.

Subchronic Toxicity of Tetrahydrofuran Vapors in Rats and Mice. CHHABRA, R. S., ELWELL, M. R., CHOU, B., MILLER, R. A., AND RENNE, R. A. (1990). Fundam. Appl. Toxicol. 14, 338–345. Tetrahydrofuran...

Percutaneous nephrolithotomy / (1987)

Miller, R. A. (Ronald Alan)

Thesis (M.S.)--St. Bartholomew's Hospital Medical College, 1987.

ENDOSCOPIC INSTRUMENTATION: EVOLUTION, PHYSICAL PRINCIPLES AND CLINICAL ASPECTS (1986)

Miller, R A

The scope and success of endoscopic surgery has relied heavily on the development of sophisticated endoscopes and their accessories. In this section the principles of optical physics, optical design...

RIGID ENDOSCOPES: OPITICAL AND DESIGN CONSIDERATIONS (1986)

Miller, R A, Hollingsworth, T R

The major design problem of rigid endoscopes is caused by the relatively small external diameter. Within this small space the manufacturer must pack a rod lens system, an illuminating fibre bundle...

ENDOSCOPIC SURGERY OF THE UPPER URINARY TRACT (1986)

Miller, R A

No surgical speciality has been more radically changed by the advent of endoscopy than urology. While the lower urinary tract is accessible through an elastic capacious urethra, the upper urinary...

Pressure drop through porous media Parts I through IV of this article appeared in the Transactions of the American Institute of Chemical Engineers and Chemical Engineering Progress (1 to 4). (1956)

Brownell, Lloyd E. (Lloyd Earl), Gami, D. C., Miller, R. A., Nekarvis, W. F.

Fluid flow data are presnted for beds of uniformly sized spheres consolidated with resin over a porosity range from 36.4 to 12.3%. The data are analyzed in terms of an effective pore volume and...

Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI.

Young, S W, Qing, F, Harriman, A, Sessler, J L, Dow, W C, Mody, T D, ...

Gadolinium(III) texaphyrin (Gd-tex2+) is representative of a new class of radiation sensitizers detectable by magnetic resonance imaging (MRI). This porphyrin-like complex has a high electron...

Medical diagnostic decision support systems--past, present, and future: a threaded bibliography and brief commentary.

Miller, R A

Articles about medical diagnostic decision support (MDDS) systems often begin with a disclaimer such as, "despite many years of research and millions of dollars of expenditures on medical diagnostic...

Evaluation of long-term maintenance of a large medical knowledge base.

Giuse, D A, Giuse, N B, Miller, R A

OBJECTIVE: Evaluate the effects of long-term maintenance activities on existing portions of a large internal medicine knowledge base. DESIGN: Five physicians who were not among the original...

A temporal analysis of QMR.

Aliferis, C F, Cooper, G F, Miller, R A, Buchanan, B G, Bankowitz, R, Giuse, N

OBJECTIVE: To understand better the trade-offs of not incorporating explicit time in Quick Medical Reference (QMR), a diagnostic system in the domain of general internal medicine, along the...

Development of a replicated database of DHCP data for evaluation of drug use.

Graber, S E, Seneker, J A, Stahl, A A, Franklin, K O, Neel, T E, Miller, R A

This case report describes development and testing of a method to extract clinical information stored in the Veterans Affairs (VA) Decentralized Hospital Computer System (DHCP) for the purpose of...

The Vanderbilt University fast track to IAIMS: transition from planning to implementation.

Stead, W W, Borden, R, Bourne, J, Giuse, D, Giuse, N, Harris, T R, ...

Vanderbilt University Medical Center is implementing an Integrated Advanced Information Management System (IAIMS) using a fast-track approach. The elapsed time between start-up and completion of...

Role of oxidants in microbial pathophysiology.

Miller, R A, Britigan, B E

Reactive oxidant species (superoxide, hydrogen peroxide, hydroxyl radical, hypohalous acid, and nitric oxide) are involved in many of the complex interactions between the invading microorganism and...

Protease cleavage of iron-transferrin augments pyocyanin-mediated endothelial cell injury via promotion of hydroxyl radical formation.

Miller, R A, Rasmussen, G T, Cox, C D, Britigan, B E

Although a number of bacterium- and host-derived factors have been suggested to contribute to the pathogenesis of Pseudomonas aeruginosa-associated tissue injury, the mechanism remains unclear. We...

Mycobacterium avium-M. intracellulare isolates from patients with or without acquired immunodeficiency syndrome.

Horsburgh, C R, Cohn, D L, Roberts, R B, Masur, H, Miller, R A, Tsang, A Y, ...

Susceptibility testing and serotyping were performed on 57 isolates of Mycobacterium avium-M. intracellulare from patients with acquired immunodeficiency syndrome (AIDS) and 75 isolates from patients...

Antimicrobial Susceptibility Testing of Aquatic Bacteria: Quality Control Disk Diffusion Ranges for Escherichia coli ATCC 25922 and Aeromonas salmonicida subsp. salmonicida ATCC 33658 at 22 and 28°C

Miller, R. A., Walker, R. D., Baya, A., Clemens, K., Coles, M., Hawke, J. P., ...

Quality control (QC) ranges for disk diffusion susceptibility testing of aquatic bacterial isolates were proposed as a result of a multilaboratory study conducted according to procedures established...

Using POSTDOC to recognize biomedical concepts in medical school curricular documents.

Kanter, S L, Miller, R A, Tan, M, Schwartz, J

Recognition of the biomedical concepts in a document is prerequisite to further processing of the document: medical educators examine curricular documents to discover the coverage of certain topics,...

Medical Subject Headings and medical terminology: an analysis of terminology used in hospital charts.

Masarie, F E, Miller, R A

Terminology used by health professionals in everyday written discourse was compared with terminology in a standardized medical vocabulary, the Medical Subject Headings (MeSH). Fifty written hospital...

Reaction of human sera with Eubacterium brachy: isolation and characterization of an extracellular antigen.

Vincent, J W, Falkler, W A, Dalessandro, N F, Miller, R A, Heath, J R

Recent studies have demonstrated an association of Eubacterium sp. with the subgingival microflora of patients with chronic periodontitis. One species, Eubacterium brachy, was evaluated to determine...

Immunochemical characterization of a protein associated with Mycobacterium leprae cell wall.

Gillis, T P, Miller, R A, Young, D B, Khanolkar, S R, Buchanan, T M

A panel of nine monoclonal antibodies to Mycobacterium leprae were used to characterize a protein antigen of the bacillus. Two monoclonal antibodies (IVD8 and IIIE9) were specific for M. leprae and...

Detection of Cryptosporidium oocysts in sputum during screening for mycobacteria.

Miller, R A, Wasserheit, J N, Kirihara, J, Coyle, M B

We report a case in which Cryptosporidium oocysts were detected during routine auramine screening of a sputum specimen for acid-fast bacilli. The patient was a 28-year-old male with acquired immune...

Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation.

Miller, R A, Britigan, B E

Previous work has shown that the Pseudomonas-derived protease, pseudomonas elastase (PAE), can modify transferrin to form iron complexes capable of catalyzing the formation of hydroxyl radical (.OH)...

Human T cell leukemia virus-I-associated T-suppressor cell inhibition of erythropoiesis in a patient with pure red cell aplasia and chronic T gamma-lymphoproliferative disease.

Levitt, L J, Reyes, G R, Moonka, D K, Bensch, K, Miller, R A, Engleman, E G

Human retroviruses have recently been linked with T cell lymphoproliferative disorders and with the acquired immune deficiency syndrome. We investigated the mechanisms for acquired pure red cell...

Isolation and Properties of Deoxyribonucleic Acid from Protoplasts of Cell Suspension Cultures of Ammi visnaga and Carrot (Daucus carota) 1

Ohyama, K., Gamborg, O. L., Miller, R. A.

A procedure is described for the isolation of native DNA from protoplasts of ammi (Ammi visnaga) and carrot (Daucus carota) cells. Protoplasts were produced from 40 grams of fresh cells by enzyme...

Outpatient clinic: where is the delay?

Patel, H R H, Luxman, C N, Bailey, T S, Brunning, J D M, Zemmel, D, Morrell, L K, ...

In outpatient clinics, consultation times are often eroded by extraneous activities. We measured the components of each outpatient episode in 167 patients attending a general urology follow-up...

Day-case surgery: enhanced recovery with flumazenil.

Birch, B R, Anson, K M, Clifford, E, Miller, R A

In an open, randomized, parallel group study of 84 adult patients undergoing elective day-case urological surgery the specific benzodiazepine antagonist flumazenil was shown to reverse effectively...

Temporary prostatic stenting and androgen suppression: a new minimally invasive approach to malignant prostatic retention.

Anson, K M, Barnes, D G, Briggs, T P, Watson, G M, Miller, R A

Urinary retention secondary to carcinoma of the prostate is usually treated by 'channel' transurethral resection of the prostate either performed alone or in combination with hormone manipulation....

Introduction of a microcomputer for health research in a developing country--the Bangladesh experience.

Frerichs, R R, Miller, R A

In November 1984, a powerful microcomputer was taken to Dhaka, Bangladesh, to aid health professionals at the National Institute for Preventive and Social Medicine (NIPSOM) in processing and...

Multiple-trait quantitative trait loci analysis using a large mouse sibship.

Jackson, A U, Fornés, A, Galecki, A, Miller, R A, Burke, D T

Quantitative trait loci influencing several phenotypes were assessed using a genetically heterogeneous mouse population. The 145 individuals were produced by a cross between (BALB/cJ x C57BL/6J)F1...

Morphology of neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice.

Miller, R A, Boorman, G A

1,3-Butadiene (CAS No. 106-99-0) was studied for potential carcinogenicity and chronic toxicity by inhalation in B6C3F1 mice. Groups of 50 mice of each sex were exposed to 0, 625, or 1250 ppm...

Inhalation toxicology of isoprene in F344 rats and B6C3F1 mice following two-week exposures.

Melnick, R L, Roycroft, J H, Chou, B J, Ragan, H A, Miller, R A

Isoprene (2-methyl-1,3-butadiene) was selected for toxicologic evaluations because of its structural similarity to 1,3-butadiene, a potent rodent carcinogen. Two-week inhalation toxicology studies of...

Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.

Melnick, R L, Huff, J E, Roycroft, J H, Chou, B J, Miller, R A

1,3-Butadiene, a large-production volume chemical used mainly in the manufacture of synthetic rubber, was found to induce multiple-organ carcinogenicity in male and female B6C3F1 mice at exposure...

Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI.

Young, S W, Qing, F, Harriman, A, Sessler, J L, Dow, W C, Mody, T D, ...

Gadolinium(III) texaphyrin (Gd-tex2+) is representative of a new class of radiation sensitizers detectable by magnetic resonance imaging (MRI). This porphyrin-like complex has a high electron...

Medical diagnostic decision support systems--past, present, and future: a threaded bibliography and brief commentary.

Miller, R A

Articles about medical diagnostic decision support (MDDS) systems often begin with a disclaimer such as, "despite many years of research and millions of dollars of expenditures on medical diagnostic...

Evaluation of long-term maintenance of a large medical knowledge base.

Giuse, D A, Giuse, N B, Miller, R A

OBJECTIVE: Evaluate the effects of long-term maintenance activities on existing portions of a large internal medicine knowledge base. DESIGN: Five physicians who were not among the original...

A temporal analysis of QMR.

Aliferis, C F, Cooper, G F, Miller, R A, Buchanan, B G, Bankowitz, R, Giuse, N

OBJECTIVE: To understand better the trade-offs of not incorporating explicit time in Quick Medical Reference (QMR), a diagnostic system in the domain of general internal medicine, along the...

Development of a replicated database of DHCP data for evaluation of drug use.

Graber, S E, Seneker, J A, Stahl, A A, Franklin, K O, Neel, T E, Miller, R A

This case report describes development and testing of a method to extract clinical information stored in the Veterans Affairs (VA) Decentralized Hospital Computer System (DHCP) for the purpose of...

The Vanderbilt University fast track to IAIMS: transition from planning to implementation.

Stead, W W, Borden, R, Bourne, J, Giuse, D, Giuse, N, Harris, T R, ...

Vanderbilt University Medical Center is implementing an Integrated Advanced Information Management System (IAIMS) using a fast-track approach. The elapsed time between start-up and completion of...

Role of oxidants in microbial pathophysiology.

Miller, R A, Britigan, B E

Reactive oxidant species (superoxide, hydrogen peroxide, hydroxyl radical, hypohalous acid, and nitric oxide) are involved in many of the complex interactions between the invading microorganism and...

Protease cleavage of iron-transferrin augments pyocyanin-mediated endothelial cell injury via promotion of hydroxyl radical formation.

Miller, R A, Rasmussen, G T, Cox, C D, Britigan, B E

Although a number of bacterium- and host-derived factors have been suggested to contribute to the pathogenesis of Pseudomonas aeruginosa-associated tissue injury, the mechanism remains unclear. We...

Mycobacterium avium-M. intracellulare isolates from patients with or without acquired immunodeficiency syndrome.

Horsburgh, C R, Cohn, D L, Roberts, R B, Masur, H, Miller, R A, Tsang, A Y, ...

Susceptibility testing and serotyping were performed on 57 isolates of Mycobacterium avium-M. intracellulare from patients with acquired immunodeficiency syndrome (AIDS) and 75 isolates from patients...

Antimicrobial Susceptibility Testing of Aquatic Bacteria: Quality Control Disk Diffusion Ranges for Escherichia coli ATCC 25922 and Aeromonas salmonicida subsp. salmonicida ATCC 33658 at 22 and 28°C

Miller, R. A., Walker, R. D., Baya, A., Clemens, K., Coles, M., Hawke, J. P., ...

Quality control (QC) ranges for disk diffusion susceptibility testing of aquatic bacterial isolates were proposed as a result of a multilaboratory study conducted according to procedures established...

Using POSTDOC to recognize biomedical concepts in medical school curricular documents.

Kanter, S L, Miller, R A, Tan, M, Schwartz, J

Recognition of the biomedical concepts in a document is prerequisite to further processing of the document: medical educators examine curricular documents to discover the coverage of certain topics,...

Medical Subject Headings and medical terminology: an analysis of terminology used in hospital charts.

Masarie, F E, Miller, R A

Terminology used by health professionals in everyday written discourse was compared with terminology in a standardized medical vocabulary, the Medical Subject Headings (MeSH). Fifty written hospital...

Reaction of human sera with Eubacterium brachy: isolation and characterization of an extracellular antigen.

Vincent, J W, Falkler, W A, Dalessandro, N F, Miller, R A, Heath, J R

Recent studies have demonstrated an association of Eubacterium sp. with the subgingival microflora of patients with chronic periodontitis. One species, Eubacterium brachy, was evaluated to determine...

Immunochemical characterization of a protein associated with Mycobacterium leprae cell wall.

Gillis, T P, Miller, R A, Young, D B, Khanolkar, S R, Buchanan, T M

A panel of nine monoclonal antibodies to Mycobacterium leprae were used to characterize a protein antigen of the bacillus. Two monoclonal antibodies (IVD8 and IIIE9) were specific for M. leprae and...

Detection of Cryptosporidium oocysts in sputum during screening for mycobacteria.

Miller, R A, Wasserheit, J N, Kirihara, J, Coyle, M B

We report a case in which Cryptosporidium oocysts were detected during routine auramine screening of a sputum specimen for acid-fast bacilli. The patient was a 28-year-old male with acquired immune...

Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation.

Miller, R A, Britigan, B E

Previous work has shown that the Pseudomonas-derived protease, pseudomonas elastase (PAE), can modify transferrin to form iron complexes capable of catalyzing the formation of hydroxyl radical (.OH)...

Human T cell leukemia virus-I-associated T-suppressor cell inhibition of erythropoiesis in a patient with pure red cell aplasia and chronic T gamma-lymphoproliferative disease.

Levitt, L J, Reyes, G R, Moonka, D K, Bensch, K, Miller, R A, Engleman, E G

Human retroviruses have recently been linked with T cell lymphoproliferative disorders and with the acquired immune deficiency syndrome. We investigated the mechanisms for acquired pure red cell...

Isolation and Properties of Deoxyribonucleic Acid from Protoplasts of Cell Suspension Cultures of Ammi visnaga and Carrot (Daucus carota) 1

Ohyama, K., Gamborg, O. L., Miller, R. A.

A procedure is described for the isolation of native DNA from protoplasts of ammi (Ammi visnaga) and carrot (Daucus carota) cells. Protoplasts were produced from 40 grams of fresh cells by enzyme...

Outpatient clinic: where is the delay?

Patel, H R H, Luxman, C N, Bailey, T S, Brunning, J D M, Zemmel, D, Morrell, L K, ...

In outpatient clinics, consultation times are often eroded by extraneous activities. We measured the components of each outpatient episode in 167 patients attending a general urology follow-up...

Day-case surgery: enhanced recovery with flumazenil.

Birch, B R, Anson, K M, Clifford, E, Miller, R A

In an open, randomized, parallel group study of 84 adult patients undergoing elective day-case urological surgery the specific benzodiazepine antagonist flumazenil was shown to reverse effectively...

Temporary prostatic stenting and androgen suppression: a new minimally invasive approach to malignant prostatic retention.

Anson, K M, Barnes, D G, Briggs, T P, Watson, G M, Miller, R A

Urinary retention secondary to carcinoma of the prostate is usually treated by 'channel' transurethral resection of the prostate either performed alone or in combination with hormone manipulation....

Introduction of a microcomputer for health research in a developing country--the Bangladesh experience.

Frerichs, R R, Miller, R A

In November 1984, a powerful microcomputer was taken to Dhaka, Bangladesh, to aid health professionals at the National Institute for Preventive and Social Medicine (NIPSOM) in processing and...

Multiple-trait quantitative trait loci analysis using a large mouse sibship.

Jackson, A U, Fornés, A, Galecki, A, Miller, R A, Burke, D T

Quantitative trait loci influencing several phenotypes were assessed using a genetically heterogeneous mouse population. The 145 individuals were produced by a cross between (BALB/cJ x C57BL/6J)F1...

Morphology of neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice.

Miller, R A, Boorman, G A

1,3-Butadiene (CAS No. 106-99-0) was studied for potential carcinogenicity and chronic toxicity by inhalation in B6C3F1 mice. Groups of 50 mice of each sex were exposed to 0, 625, or 1250 ppm...

Inhalation toxicology of isoprene in F344 rats and B6C3F1 mice following two-week exposures.

Melnick, R L, Roycroft, J H, Chou, B J, Ragan, H A, Miller, R A

Isoprene (2-methyl-1,3-butadiene) was selected for toxicologic evaluations because of its structural similarity to 1,3-butadiene, a potent rodent carcinogen. Two-week inhalation toxicology studies of...

Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.

Melnick, R L, Huff, J E, Roycroft, J H, Chou, B J, Miller, R A

1,3-Butadiene, a large-production volume chemical used mainly in the manufacture of synthetic rubber, was found to induce multiple-organ carcinogenicity in male and female B6C3F1 mice at exposure...

Outpatients: can we save time and reduce waiting lists?

Duncan, M, Beale, K, Parry, J, Miller, R A

The amount of time that one consultant urologist wasted on unnecessary administration while seeing outpatients was noted over six weeks. Searching for missing clinical data and the time spent on...

Dental anesthetic management of a patient with ventricular arrhythmias.

Miller, R. A., Siegelman, L. I.

During routine deep sedation for endodontic therapy, a dentist-anesthesiologist observed premature ventricular contractions (PVCs) on a 62-yr-old woman's electrocardiogram (EKG) tracing. The dentist...

Conditional Choice Probabilities and the Estimation of Dynamic Models.

Hotz, V.J., Miller, R.A.

economic models ; microeconomics ; fertility ; decision making

Sedation for day-case urology: an assessment of patient recovery profiles after midazolam and flumazenil.

Birch, B. R., Anson, K. M., Kalmanovitch, D. V., Cooper, J., Miller, R. A.

The specific antagonist flumazenil has been shown to reverse the central actions of benzodiazepines. Its use, in day-case procedures performed under benzodiazepine sedation, offers the potential for...

Outpatients: can we save time and reduce waiting lists?

Duncan, M, Beale, K, Parry, J, Miller, R A

The amount of time that one consultant urologist wasted on unnecessary administration while seeing outpatients was noted over six weeks. Searching for missing clinical data and the time spent on...

Clinical application of the UMLS in a computerized order entry and decision-support system.

Geissbuhler, A., Miller, R. A.

Vanderbilt University Medical Center uses the UMLS as a dictionary, an interlingua, and a knowledge source within the WizOrder system. WizOrder provides direct care-provider order entry and...

Distributing knowledge maintenance for clinical decision-support systems: the "knowledge library" model.

Geissbuhler, A., Miller, R. A.

The maintenance of knowledge-rich clinical decision-support systems is challenging, in particular in the complex setting of a large academic medical center. Distributing the maintenance tasks to the...

A new approach to the implementation of direct care-provider order entry.

Geissbühler, A., Miller, R. A.

Successful implementation of direct computer-based care-provider order entry traditionally relies on one of two different approaches development from scratch or installation of a commercial product....

Modeling principles for QMR medical findings.

Rassinoux, A. M., Miller, R. A., Baud, R. H., Scherrer, J. R.

Structured representation of medical information is essential for ensuring the accuracy and reliability of computerized decision support applications. Such systems require input that is error-free...

Design of a general clinical notification system based on the publish-subscribe paradigm.

Geissbühler, A., Grande, J. F., Bates, R. A., Miller, R. A., Stead, W. W.

We describe the design and initial implementation of a notification sub-system, as a component of a modern information management architecture. The system, based on the publish-subscribe paradigm,...

Compositional and enumerative designs for medical language representation.

Rassinoux, A. M., Miller, R. A., Baud, R. H., Scherrer, J. R.

Medical language is in essence highly compositional, allowing complex information to be expressed from more elementary pieces. Embedding the expressive power of medical language into formal systems...

A computer based intervention on the appropriate use of arterial blood gas.

Bansal, P., Aronsky, D., Aronsky, D., Talbert, D., Miller, R. A.

OBJECTIVE: To evaluate impact of a computer-based intervention on arterial blood gas (ABG) usage in an intensive care setting. DESIGN: Retrospectively examined, via mixed group analysis, the effects...

The effects on clinician ordering patterns of a computerized decision support system for neuroradiology imaging studies.

Sanders, D. L., Miller, R. A.

OBJECTIVE: To evaluate the impact of computerized ordering guidelines on clinician ordering patterns for neuroradiology imaging studies of the head. DESIGN: A retrospective analysis was performed...

Experience using a programmable rules engine to implement a complex medical protocol during order entry.

Starmer, J. M., Talbert, D. A., Miller, R. A.

WizOrder, Vanderbilt University Medical Center's (VUMC) clinician order entry system, is an excellent platform for delivering high-quality decision support to clinical end-users. A scripting language...

User Variability in Abstracting and Entering Printed Case Histories with QUICK MEDICAL REFERENCE (QMR)

Bankowitz, R.A., Blumenfeld, B.H., Bettinsoli, N. Giuse, Parker, R.C., McNeil, M., Challinor, S., ...

The variability in abstracting and entering printed case histories into the Quick Medical Reference (QMR) diagnostic computer program was explored. Six study physicians who were familiar with the use...

A tool for the computer-assisted creation of QMR medical knowledge base disease profiles.

Giuse, D. A., Giuse, N. B., Miller, R. A.

QMR-KAT is a computer-based tool which assists physicians in the construction of the QMR medical knowledge base. Each QMR disease profile results from an in-depth analysis of the published medical...

CHARTLINE: providing bibliographic references relevant to patient charts using the UMLS Metathesaurus Knowledge Sources.

Miller, R. A., Gieszczykiewicz, F. M., Vries, J. K., Cooper, G. F.

A successful medical informatics program helps its users to match their information needs as closely and efficiently as possible to the capabilities of the system. CHARTLINE is a computer program...

The NLC Positron Source

Tang Kulikov Clendenin, H. Tang, A. V. Kulikov, J. E. Clendenin, S. D. Ecklund, R. A. Miller, ...

this paper we present a baseline design that is reasonably conservative and uses only existing technologies. We use the SLC positron source [3] as the basis for our design, as its design principles...