R. B. Heap

Publication List Details

Period

1979 - 1979

Number

18

Co-Authors

Blocking of pregnancy in mice by immunization with anti-idiotype directed against monoclonal anti-progesterone antibody.

Wang, M W, Heap, R B, Taussig, M J

Passive transfer of monoclonal anti-progesterone antibodies shortly after mating blocks the onset of pregnancy in different species (mouse, rat, and ferret). Here we report that BALB/c mice can be...

Purification and characterization of heparin-binding growth factors from porcine uterus.

Brigstock, D R, Heap, R B, Barker, P J, Brown, K D

Heparin-binding growth factors present in pig uterine tissue were purified by approx. 50,000-fold using a combination of ammonium sulphate precipitation, ion-exchange chromatography and...

Studies on the biosynthesis in vivo and excretion of 16-unsaturated C19 steroids in the boar

Saat, Y. A., Gower, D. B., Harrison, F. A., Heap, R. B.

1. In one experiment [7α-3H]pregnenolone was infused continuously for 12min into the left spermatic artery of a sexually mature boar and blood was collected during this period by continuous drainage...

Studies on the metabolism of 5α-androst-16-en-3-one in boar testis in vivo

Saat, Y. A., Gower, D. B., Harrison, F. A., Heap, R. B.

1. [5α-3H]5α-Androst-16-en-3-one (5α-androstenone) was infused at a constant rate for 180min into the spermatic artery of a sexually mature boar. Samples of spermatic-venous blood were collected...

The ultrastructure of the sheep placenta around the time of parturition.

Perry, J S, Heap, R B, Ackland, N

Placental tissue, taken from seven sheep before, during and after delivery, was fixed and sectioned for study by transmission electron microscopy. Daily blood samples from the same sheep were taken...

The role of trophoblastic binucleate cells in implantation in the goat: a morphological study.

Wango, E O, Wooding, F B, Heap, R B

In the goat conceptus individual intra-epithelial trophectodermal binucleate cells first appear 18 days post coitum and their incidence rapidly increases where the trophectoderm is apposed to the...

Blocking of pregnancy in mice by immunization with anti-idiotype directed against monoclonal anti-progesterone antibody.

Wang, M W, Heap, R B, Taussig, M J

Passive transfer of monoclonal anti-progesterone antibodies shortly after mating blocks the onset of pregnancy in different species (mouse, rat, and ferret). Here we report that BALB/c mice can be...

Purification and characterization of heparin-binding growth factors from porcine uterus.

Brigstock, D R, Heap, R B, Barker, P J, Brown, K D

Heparin-binding growth factors present in pig uterine tissue were purified by approx. 50,000-fold using a combination of ammonium sulphate precipitation, ion-exchange chromatography and...

Studies on the metabolism of 5α-androst-16-en-3-one in boar testis in vivo

Saat, Y. A., Gower, D. B., Harrison, F. A., Heap, R. B.

1. [5α-3H]5α-Androst-16-en-3-one (5α-androstenone) was infused at a constant rate for 180min into the spermatic artery of a sexually mature boar. Samples of spermatic-venous blood were collected...

Studies on the biosynthesis in vivo and excretion of 16-unsaturated C19 steroids in the boar

Saat, Y. A., Gower, D. B., Harrison, F. A., Heap, R. B.

1. In one experiment [7α-3H]pregnenolone was infused continuously for 12min into the left spermatic artery of a sexually mature boar and blood was collected during this period by continuous drainage...

The ultrastructure of the sheep placenta around the time of parturition.

Perry, J S, Heap, R B, Ackland, N

Placental tissue, taken from seven sheep before, during and after delivery, was fixed and sectioned for study by transmission electron microscopy. Daily blood samples from the same sheep were taken...

The role of trophoblastic binucleate cells in implantation in the goat: a morphological study.

Wango, E O, Wooding, F B, Heap, R B

In the goat conceptus individual intra-epithelial trophectodermal binucleate cells first appear 18 days post coitum and their incidence rapidly increases where the trophectoderm is apposed to the...

Anti-idiotypic sera against monoclonal anti-progesterone antibodies: production in rabbits and rats and characterization of specificity.

Taussig, M J, Brown, N, Ellis, S, Holliman, A, Peat, D, Richardson, N, ...

Antisera were raised in rabbits and rats against three mouse monoclonal anti-progesterone IgG1 antibodies. Anti-idiotypic antibodies were isolated from rabbit sera by successive passage over...

Analysis of an anti-progesterone antibody: variable crystal morphology of the Fab' and steroid-Fab' complexes.

Stura, E A, Arevalo, J H, Feinstein, A, Heap, R B, Taussig, M J, Wilson, I A

Anti-progesterone monoclonal antibodies are being used for structural studies of antibody-antigen interaction, for their ability to block pregnancy shortly after fertilization, and for hormone...

Prostaglandins in pyometrial fluid from the cow, bitch and ferret.

Heap, R B

1 Pyometra is a disorder of the uterus usually associated with bacterial infection plus obstruction. 2 Large quantities of fluid often collect in the uterus during this condition. 3 Pyometrial fluid...