Advanced Technology Large-Aperture Space Telescope (ATLAST): Characterizing Habitable Worlds (2009)
Postman, M., Traub, W., Krist, J., Stapelfeldt, K., Brown, R., Oegerle, W., ...
The Advanced Technology Large Aperture Space Telescope (ATLAST) is a set of mission concepts for the next generation UV-Optical-Near Infrared space telescope with an aperture size of 8 to 16 meters....
Terrestrial Planet Finder Coronagraph (TPF-C) Flight Baseline Concept (2009)
Levine, Marie, Lisman, D., Shaklan, S., Kasting, J., Traub, W., Alexander, J., ...
The Terrestrial Planet Finder Coronagraph (TPF-C) mission presented here is an existence proof for a flagship-class internal coronagraph space mission capable of detecting and characterizing...
Exoplanet Characterization and the Search for Life (2009)
Kasting, J., Traub, W., Roberge, A., Leger, A., Schwartz, A., Wooten, A., ...
Over 300 extrasolar planets (exoplanets) have been detected orbiting nearby stars. We now hope to conduct a census of all planets around nearby stars and to characterize their atmospheres and...
We present another proof that TT1(S 1) = Z\. Actually our main purpose is to show that the techniques used by P. Olum in [1] also allow one to prove the following result. Let X = AKJB be a...
I. C. Baianu, R. Brown, J. F. Glazebrook
Abstract A categorical ontology of space and time is presented for emergent biosystems, super-complex dynamics, evolution and human consciousness. Relational structures of organisms and the human...
SUBGROUPS OF FREE TOPOLOGICAL GROUPS AND FREE TOPOLOGICAL PRODUCTS OF TOPOLOGICAL GROUPS (2009)
Our objectives are topological versions of the Nielsen-Schreier Theorem on subgroups of free groups, and the Kurosh Theorem on subgroups of free products of groups. It is known that subgroups of free...
Graphs of morphisms of graphs (2009)
R. Brown, I. Morris, J. Shrimpton, C. D. Wensley
endomorphism monoid, symmetry object. This is an account for the combinatorially minded reader of various categories of directed and undirected graphs, and their analogies with the category of sets....
Stearns, V, Jacobs, L, Khouri, N, Jeter, S, Powers, P, Shahverdi, K, ...
No abstract available.
The CMS barrel calorimeter response to particle beams from 2 to 350 GeV/c (2009)
Abdullin, S., Abramov, V., Acharya, B., Adam, N., Adams, M., Adzic, P., ...
Ziemann, C., Jackson, P., Brown, R., Attik, G., Rihn, B.H., Creutzenberg, O.
Inhalation of some respirable crystalline silica (MMAD < approx. 4 ?m) leads to inflammatory and malignant diseases. Comprehensive physicochemical/biological data and suitable in vitro/in vivo...
Creutzenberg, O., Ziemann, C., Hansen, T., Ernst, H., Jackson, P., Cartlidge, D., ...
As various quartz polymorphs react differently in lungs, a differentiation of effects is needed while setting occupational exposure levels. The objective of this European Collective Research Project...
Ziemann, C., Jackson, P., Brown, R., Attik, G., Rihn, B.H., Creutzenberg, O.
Inhalation of some respirable crystalline silica (MMAD < approx. 4 ?m) leads to inflammatory and malignant diseases. Comprehensive physicochemical/biological data and suitable in vitro/in vivo...
Creutzenberg, O., Ziemann, C., Hansen, T., Ernst, H., Jackson, P., Cartlidge, D., ...
As various quartz polymorphs react differently in lungs, a differentiation of effects is needed while setting occupational exposure levels. The objective of this European Collective Research Project...
Diversity among other worlds: characterization of exoplanets by direct detection (2008)
Schneider, J., Boccaletti, A., Aylward, A., Baudoz, P., Brown, R., ...
The physical characterization of exoplanets will require to take spectra at several orbital positions. For that purpose, a direct imaging capability is necessary. Direct imaging requires an efficient...
Brown, R.; Department Of Earth Sciences, University Of Bristol,, Orsi, G.; Istituto Nazionale Di Geofisica E Vulcanologia, Sezione OV, Napoli, Italia, De Vita, S.; Istituto Nazionale Di Geofisica E Vulcanologia, Sezione OV, Napoli, Italia
A new pyroclastic stratigraphy is presented for the island of Ischia, Italy, for the period ∼75–50 ka BP. The data indicate that this period bore witness to the largest eruptions recorded on the...
U. P. Wild, F. Güttler, M. Pirotta, A. Renn, M. Orrit, J. Bernard, ...
(1997). 44. R. A. Keller et al., Appl. Spectrosc. 50, 12A (1996).
B. Bernhardt, F. Nikpourian, C. Delta, Y. Abad, R. Brown, B. Bernhardt, ...
Digest, pp. 59- 62. [11] N. Burgess, “Removal of Sign-Extension Circuitry From
GLOBAL ACTIONS, GROUPOID ATLASES AND APPLICATIONS Contents (2008)
A. Bak, R. Brown, G. Minian, T. Porter
(communicated by Hvedri Inassaridze) Global actions were introduced by A. Bak to give a combinatorial
Trevethan, M., Chanson, H., Brown, R.
In natural estuaries, scalar diffusion and dispersion are driven by turbulence. In the present study, detailed turbulence measurements were conducted in a small subtropical estuary with semi-diurnal...
Trevethan, M., Chanson, H., Brown, R.
In natural estuaries, scalar diffusion and dispersion are driven by turbulence. In the present study, detailed turbulence measurements were conducted in a small subtropical estuary with semi-diurnal...
Stanton, G, David, M, Hall, G, Brown, R, Ebdon, L, Kendall, S, ...
Over a decade has gone by since the report of the Widening Participation Committee - Learning works - was presented to the Further Education Funding Council. Ten years on, this report asks how far...
Synchronous running of shaded-pole permanent magnet motors (2008)
A mathematical model for the rotary motion of a shaded-pole permanent magnet motor is established and significant non-dimensional combinations of the electrical and mechanical parameters of the motor...
Campanile, D., Nambiar, C.G., Bishop, P., Widdowson, M., Brown, R.
The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic...
A Posteriori Restoration of Block Transform-Compressed Data (2007)
Block transform-compression techniques such as JPEG operate by systematically decomposing image data into segments or blocks that are transformed, quantized, and encoded independently. In this work...
Emittance Measurements Of The High Intensity Polarized Ion Source At Iucf (2007)
Derenchuk Brown Petri, R. Brown, H. Petri, E. Stephenson, M. Wedekind
The IUCF high intensity polarized ion source (HIPIOS) is now being routinely used to deliver beam to experiments. Recent efforts have been focussed on measuring beam properties in order to improve...
Performance Optimization of Pipelined Caches (2007)
O. Olukotun, T. Mudge, R. Brown
This paper formulates and shows how to solve the problem of selecting the cache size and depth of cache pipelining that maximizes the performance of a given instruction-set architecture. The solution...
FIRST CONCLUSIONS OF THE LOSSES MANAGEMENT WORKING GROUP (2007)
J. Borburgh, R. Brown, M. Chanel, V. Vohan, M. Gourber-pace, S. Hancock, ...
At the PPC meeting which was held on October 6 th, 2000, it was decided to create a sub-panel “to study the problem of the beam losses in view of the possibility that the average beam intensity...
A. Bak, R. Brown, G. Minian, T. Porter
The aim of these notes is to give a summary of the research seminars, discussions etc in the ARC project, to start the integration of the ideas, examples and theory into a more coherent whole and to...
The provision of critical care outreach services in England: findings from a national survey (2007)
McDonnell, A., Esmonde, L., Morgan, R., Brown, R., Bray, K., Parry, G., ...
Purpose: The aim of this study was to describe the development, introduction, implementation, and current models of critical care outreach services.Materials and Methods: We conducted a national...
In this paper we identify four formats of classroom talk for integrating everyday and scientific discourse – replacement, interweaving, contextual privileging and pastiche. In the replacement...
Campanile, D., Nambiar, C.G., Bishop, P., Widdowson, M., Brown, R.
The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic...
In this paper we identify four formats of classroom talk for integrating everyday and scientific discourse – replacement, interweaving, contextual privileging and pastiche. In the replacement...
I. C. Baianu, R. Brown, J. F. Glazebrook
structures with remarkable asymmetries or broken symmetries, such as the CPTsymmetry violation, is proposed. This has the potential for novel applications of Higher Dimensional Algebra to SpaceTime...
Theory in a Categorical Ontology of Space and Time. This conceptual and formal (2007)
R. Brown, J. F. Glazebrook, I. C. Baianu
Abstract A novel conceptual framework is introduced for the Complexity Levels
Smith, L.V., Parenty, A.D.C., Guthrie, K.M., Plumb, J., Brown, R., Cronin, L.
We have synthesised a library of dihydroimidazophenanthridinium cations (DIPs) with large structural diversity (1-29) using a one-pot approach. The DNA binding constants of DIPs range from 2×104 to...
De Graeff, P., Hall, J., Crijns, A.P.G., De Bock, G.H., Paul, J., Oien, K.A., ...
The prognostic impact of p53 immunostaining in a large series of tumours from epithelial ovarian cancer patients in a two-centre study was analysed. The study population (n=476) comprised of a...
Epigenetics as a mechanism driving polygenic clinical drug resistance (2006)
Glasspool, R.M., Teodoridis, J.M., Brown, R.
Aberrant methylation of CpG islands located at or near gene promoters is associated with inactivation of gene expression during tumour development. It is increasingly recognised that such...
Signalling cell cycle arrest and cell death through the MMR System (2006)
Loss of DNA mismatch repair (MMR) in mammalian cells, as well as having a causative role in cancer, has been linked to resistance to certain DNA damaging agents including clinically important...
Investigating the literature on integration, coordination and multidisciplinary care (2006)
Mitchell, G., Tieman, J., Shelby-James, T., Currow, D., Fazekas, B., Brown, R.
GRAPHS OF MORPHISMS OF GRAPHS Bangor Mathematics Preprint 06.04 (2006)
R. Brown, I. Morris, J. Shrimpton, C. D. Wensley
This is an account for the combinatorially minded reader of various categories of directed and undirected graphs, and their analogies with the category of sets. As an ap-plication, the endomorphisms...
Lapkin, A., Savill-Jowitt, C., Edler, K., Brown, R.
Keggin tungstophosphoric acid supported onto mesoporous and meso-microporous materials was studied by ammonia microcalorimetry. Experiments were performed at high and low temperatures to separate the...
Linking corrosion and catastrophic failure in low-power metallized polypropylene capacitors (2006)
Corrosion of the metallic film in cylindrical metallized film capacitors generally progresses from the end caps toward the center of the film. Promoted by the penetration of moisture from outside,...
Parenty, A.D.C., Smith, L.V., Guthrie, K.M., Long, D-L., Plumb, J., Brown, R., ...
A new class of cytotoxic heteroaromatic cations is presented, based on the dihydro-imidazo-phenanthridinium framework (DIP), that have affinity for DNA and cytotoxicity toward cancerous cells. The...
Cheema, U., Brown, R., Mudera, V., Yang, S.Y., McGrouther, G., Goldspink, G.
It has been shown that the insulin-like growth factor (IGF-I) gene is spliced in response to mechanical signals producing forms of IGF-I which have different actions. In order to study how mechanical...
Evaluation of Thermosensitive Stationary Phases in HPLC (2005)
Lynen, Frederic, BROWN, R, Heijl, Jan, Du Prez, Filip, Sandra, Patrick
Brown, R., Brown, M., Davies, M., Davies, Stephen
This paper presents a preliminary analysis of data recorded by R and M Brown on the occurrence of birds at the Middlesex Field Study Centre, Manjimup, between July 1974 and June 1999. During this...
Brown, R., Brown, M., Davies, M., Davies, Stephen
This paper presents a preliminary analysis of data recorded by R and M Brown on the occurrence of birds at the Middlesex Field Study Centre, Manjimup, between July 1974 and June 1999. During this...
Design of a digital forensics image mining system (2005)
Abstract Increasing amount of illicit image data transmitted via the internet has triggered the need to develop effective image mining systems for digital forensics purposes. This paper discusses the...
Using distributed circuits to model power capacitor behavior (2005)
Distributed circuit modeling of stacked and spiral capacitors is described. The modeling, executed on a spreadsheet, allows what-if analysis of the effects of changes in capacitor specifications such...
Maxillary incisor palatal erosion: No correlation with dietary variables? (2005)
Chadwick, R G, Manton, S L, Ward, S, Mitchell, H. L., Ogston, S, Brown, R
The objectives of the study were to examine a relationship between tooth erosion affecting the palatal aspects of permanent maxillary central incisors with dietary, behavioral and medical variables....
Maxillary incisor palatal erosion: No correlation with dietary variables? (2005)
Chadwick, R. G., Manton, S. L., Ward, S., Mitchell, H. L., Ogston, S., Brown, R.
The objectives of the study were to examine a relationship between tooth erosion affecting the palatal aspects of permanent maxillary central incisors with dietary, behavioral and medical variables....
Anion channels in roots : a role in sulphate transport. (2004)
Diatloff, Eugene, Brown, R., Roberts, Stephen K.
The efflux of both organic and inorganic anions from plant roots plays an important role in plant nutrition. We are using the patch-clamp technique to investigate anion channel activity in the...
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A.M.C., ...
Objective. To identify differentially expressed genes in synovial fibroblasts and examine the effect on gene expression of exposure to TNF-alpha and IL-1beta. Methods. Restriction fragment...
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A.M.C., ...
Objective. To identify differentially expressed genes in synovial fibroblasts and examine the effect on gene expression of exposure to TNF-alpha and IL-1beta. Methods. Restriction fragment...
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A. M. C., ...
Objective. To identify differentially expressed genes in synovial fibroblasts and examine the effect on gene expression of exposure to TNF-α and IL-1β. Methods. Restriction fragment differential...
Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene (2004)
Strathdee, G., Davies, B.R., Vass, J.K., Siddiqui, N., Brown, R.
Over 50% of human genes are associated with CpG islands and DNA methylation within such CpG islands has been clearly correlated with inhibition of expression. Whereas changes in DNA methylation play...
Cell type specific methylation of an intronic CPG-island controls expression of the MCJ gene (2004)
Strathdee, G., Davies, B. R., Vass, J. K., Siddiqui, N., Brown, R.
Over 50% of human genes are associated with CpG islands and DNA methylation within such CpG islands has been clearly correlated with inhibition of expression. Whereas changes in DNA methylation play...
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A. M. C., ...
Objective. To identify differentially expressed genes in synovial fibroblasts and examine the effect on gene expression of exposure to TNF-α and IL-1β. Methods. Restriction fragment differential...
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A. M. C., ...
Objective. To identify differentially expressed genes in synovial fibroblasts and examine the effect on gene expression of exposure to TNF-α and IL-1β. Methods. Restriction fragment differential...
Abbiendi, G, Carter, A, De Wolf, E, McPherson, R A, Neal, H, Thomson, M, ...
Hadronic Z0 decays with identified electrons or muons have been used to measure the forward-backward asymmetries of e^+e^- --> Z0 --> bbbar and e^+e^- --> Z0 --> ccbar events. The asymmetries at...
Curie-Weiss analysis of ferromagnetic and glassy transitions in nanostructured GdAl2 (2003)
Williams, D., Shand, P.M., Stark, C., Pekarek, T., Brown, R., Yue, Lanping, ...
Structural inhomogeneity on length scales comparable to magnetic interaction lengths can produce complex magnetic behavior. Crystalline GdAl2 is a ferromagnet with a Curie temperature of 170 K, while...
Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides (2003)
Brown, R., Smith, W.E., Graham, D.
The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman...
Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides (2003)
Brown, R., Smith, W.E., Graham, D.
The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman...
The STAR Time Projection Chamber: A Unique Tool for Studying High Multiplicity Events at RHIC (2003)
Anderson, M., Berkovitz, J., Betts, W., Bossingham, R., Bieser, F., Brown, R., ...
The STAR Time Projection Chamber (TPC) is used to record collisions at the Relativistic Heavy Ion Collider (RHIC). The TPC is the central element in a suite of detectors that surrounds the...
A grammar for the specification of forensic image mining search (2003)
Brown, R., Pham, B., De Vel, O.
There has been much research into the use of similarity measures to facilitate content-based image retrieval. However, there are other application areas where the user will wish to retrieve images...
Bilous, M., Ades, C., Armes, J., Bishop, J., Brown, R., Cooke, B., ...
The tests that are currently available for the measurement of overexpression of the human epidermal growth factor-2 (HER2) in breast cancer have shown considerable problems in accuracy and...
A grammar for the specification of forensic image mining search (2003)
Brown, R., Pham, B., De Vel, O.
There has been much research into the use of similarity measures to facilitate content-based image retrieval. However, there are other application areas where the user will wish to retrieve images...
A grammar for the specification of forensic image mining search (2003)
Brown, R., Pham, B., De Vel, O.
There has been much research into the use of similarity measures to facilitate content-based image retrieval. However, there are other application areas where the user will wish to retrieve images...
Coexistence of Ferromagnetic and Glassy States in Mechanically Milled GdAl2 (2002)
Stark, C., Shand, P.M., Pekarek, T.M., Williams, D., Brown, R., Yue, L., ...
Measurements of DC susceptibility, AC susceptibility, and AC susceptibility with an applied DC bias field were performed on mechanically milled GdAl2. A paramagnetic phase exists above a temperature...
Multiple categories: the equivalence of a globular and a cubical approach (2002)
Al-Agl, F.A., Brown, R., Steiner, R.
We show the equivalence of two kinds of strict multiple category, namely the well-known globular -categories, and the cubical -categories with connections.
McAnally, G., McLaughlin, C., Brown, R., Robson, D.C., Faulds, K., Tackley, D.R., ...
The synthesis of seven monoazo benzotriazole dyes for use in surface enhanced resonance Raman scattering, SERRS, is reported. The dyes are all capable of complexing to the silver surface used to...
McAnally, G., McLaughlin, C., Brown, R., Robson, D.C., Faulds, K., Tackley, D.R., ...
The synthesis of seven monoazo benzotriazole dyes for use in surface enhanced resonance Raman scattering, SERRS, is reported. The dyes are all capable of complexing to the silver surface used to...
An empirical molecular model of crystals of p-terphenyl doped with terrylene is developed and compared with recent experiments on single guest molecules. The model provides an assignment of the...
Subchronic studies on man-made vitreous fibres. Toxicity results (2002)
Brown, R., Bellmann, B., Muhle, H., Ernst, H., Pohlmann, G., Sébastien, P.
Two 'alkaline earth silicate' wools - a calcium magnesium silicate and a calcium magnesium zirconium silicate - were examinated in a subchronic '90-day' rat inhalation assay. A preparation of a...
Subchronic studies on man-made vitreous fibres. Kinetics of inhaled particles (2002)
Bellmann, B., Muhle, H., Ernst, H., Pohlmann, G., Sébastien, P., Brown, R.
After subchronic exposure of rats to different fibre types [calcium magnesium silicate fibre, calcium magnesium zirconia silicate fibre, refractory ceramic fibre (RCF), non-fibrous material of that...
R. Brown, E. J. Moore, T. Porter, C.D. Wensley
The category of crossed complexes gives an algebraic model of CW - complexes and cellular maps. Free crossed resolutions of groups contain information on a presentation of the group as well as higher...
This paper considers the impact of the introduction of graphic calculators into assessment within the International Baccalaureate Diploma. The difficulties, which arose in the development of practice...
Mathematical modelling is perceived as one way of introducing more real life activities into mathematics lessons. This article investigates the introduction of mathematical modelling into the...
Davis, M., Brown, R., Dickson, A., Horton, H., James, D., Laing, N., ...
Malignant hyperthermia (MH) is rarely associated with specific myopathies or musculoskeletal abnormalities. Three clinical investigations of MH associated with either non‐specific myopathies or...
Brown, R., Smith, W.E., Graham, D.
A method for the addition of a benzotriazole moiety to the 5'-terminus of an oligonucleotide via phosphoramidite chemistry has been developed. Use of a monomethoxytrityl protecting group on the...
Brown, R., Smith, W.E., Graham, D.
A method for the addition of a benzotriazole moiety to the 5'-terminus of an oligonucleotide via phosphoramidite chemistry has been developed. Use of a monomethoxytrityl protecting group on the...
Abreu, P., Adam, W., Adye, T., Adzic, P., Albrecht, Z., Alderweireld, T., ...
Measurements of the trilinear gauge boson couplings $WW\gamma$ and $WWZ$ are presented using the data taken by DELPHI in 1998 at a centre-of-mass energy of 189~GeV and combined with DELPHI data at...
Abreu, P., Adam, W., Adye, T., Adzic, P., Albrecht, Z., Alderweireld, T., ...
Measurements of the trilinear gauge boson couplings $WW\gamma$ and $WWZ$ are presented using the data taken by DELPHI in 1998 at a centre-of-mass energy of 189~GeV and combined with DELPHI data at...
Abreu, P., Adam, W., Adye, T., Adzic, P., Albrecht, Z., Alderweireld, T., ...
Measurements of the trilinear gauge boson couplings $WW\gamma$ and $WWZ$ are presented using the data taken by DELPHI in 1998 at a centre-of-mass energy of 189~GeV and combined with DELPHI data at...
SERRS detection of PNA and DNA labelled with a specifically designed benzotriazole azo dye (2001)
Graham, D., Brown, R., Smith, W.E.
PNA and DNA have been detected for the first time with a specifically designed non-fluorescent SERRS active label; this is also the first use of SERRS to detect PNA.
Microbacterium gubbeenense sp nov., from the surface of a smear-ripened cheese. (2001)
BRENNAN, NM, BROWN, R, GOODFELLOW, M, WARD, AC, BERESFORD, TP, Vancanneyt, Marc, ...
SERRS detection of PNA and DNA labelled with a specifically designed benzotriazole azo dye (2001)
Graham, D., Brown, R., Smith, W.E.
PNA and DNA have been detected for the first time with a specifically designed non-fluorescent SERRS active label; this is also the first use of SERRS to detect PNA.
Low-temperature Raman Spectra of Polycrystalline NH4F and ND4F (2001)
Brown, R, Fredericks, Peter, Rintoul, Llewellyn, Shurvell, Herbert
Low-temperature Raman Spectra of Polycrystalline NH4F and ND4F (2001)
Brown, R, Fredericks, Peter, Rintoul, Llewellyn, Shurvell, Herbert
Low-temperature Raman Spectra of Polycrystalline NH4F and ND4F (2001)
Brown, R, Fredericks, Peter, Rintoul, Llewellyn, Shurvell, Herbert
Low-temperature Raman Spectra of Polycrystalline NH4F and ND4F (2001)
Brown, R, Fredericks, Peter, Rintoul, Llewellyn, Shurvell, Herbert
Particle contamination in experimental fiber preparations (2000)
Brown, R., Sebastien, P., Bellmann, B., Muhle, H.
Two samples of refractory ceramic fibers (RCF1 and RCF1a) were tested in rats exposed by inhalation for 3 wk and followed thereafter for 12 mo. RCF1 and RCF1a have similar fiber chemistry but differ...
Dyson, Pamela Grace, Horvath, Noemi, Joshua, D., Barrow, L., Van Holst, N., Brown, R., ...
Copyright © 2000 Nature Publishing Group
Dyson, Pamela Grace, Horvath, Noemi, Joshua, D., Barrow, L., Van Holst, N., Brown, R., ...
Copyright © 2000 Nature Publishing Group
p53-Oriented cancer therapies: Current progress (1999)
Nearly twenty years after the initial discovery of p53, we are now in an ideal position to exploit our vast knowledge of p53 biology in the creation of novel cancer therapies. Disruption of p53...
Sequential bilateral transplantation in Parkinson's disease: Effects of the second graft (1999)
Hagell, P., Schrag, A., Piccini, P., Jahanshahi, M., Brown, R., Rehncrona, S., ...
Five parkinsonian patients who had received implants of human embryonic mesencephalic tissue unilaterally in the striatum 10–56 months earlier were grafted with tissue from four to eight donors...
Current Radiation Issues for Programmable Elements and Devices (1998)
Katz, Robert, Wang, J.J., Koga, R., LaBel, K. A., McCollum, J., Brown, R., ...
State of the art programmable devices are utilizing advanced processing technologies, non-standard circuit structures, and unique electrical elements in commercial-off-the- shelf (COTS)-based,...
Pizzorno, G, Fu, SQ, Nanakorn, T, Krause, DS, Liang, J, ...
Ad.CMV-CD is a replication incompetent adenoviral vector carrying a cytomegalovirus (CMV)-driven transcription unit of the cytosine deaminase (CD) gene. The CD transcription unit in this vector...
Measurement of the charged particle multiplicity of weakly decaying B hadrons (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Ajinenko, I, Alekseev, G D, ...
From the $Z$ decays recorded in 1994 and 1995 by the DELPHI detector at LEP, the charged particle multiplicity of weakly decaying $B$ hadrons was measured to be: \begin{center} $4.97 \pm 0.03 \pm...
Investigation of the splitting of quark and gluon jets (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Ajinenko, I, Alekseev, G D, ...
The splitting processes in identified quark and gluon jets are investigated using longitudinal and transverse observables. The jets are selected from symmetric three-jet events measured in Z decays L...
First evidence for a charm radial excitation, $D^{*}'$ (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Ajinenko, I, Alekseev, G D, ...
Using D$^{*+}$ mesons exclusively reconstructed in the DELPHI detector at LEP, an excess of $66\pm14(\mbox{stat.})$ events is observed in the D$^{*+}\pi^+\pi^-$ final state with a mass of...
A study of the hadronic resonance structure in the decay $\tau \to 3\pi\nu_{\tau}$ (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Alekseev, G D, Alemany, R, ...
The hadronic structure of the decay of the $\tau$ lepton to three charged particles, $\tau\rightarrow 3\pi\nu_\tau$, is studied using data collected by the DELPHI detector at LEP between 1992 and...
Measurement of the inclusive charmless and double-charm B branching ratios (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Alekseev, G D, Alemany, R, ...
The DELPHI experiment at LEP has measured the inclusive charmless $B$ hadron decay branching ratio, the $B$ branching ratio into two charmed particles, and the total number of charmed particles per...
Measurement of Trilinear Gauge Couplings in $e^+ e^-$ Collisions at 161 GeV and 172 GeV (1998)
Abreu, P, Adam, W, Adye, T, Adzic, P, Alekseev, G D, Alemany, R, ...
Trilinear gauge boson couplings are measured using data taken by DELPHI at 161~GeV and 172~GeV. Values for $WWV$ couplings ($V=Z, \gamma$) are determined from a study of the reactions \eeWW\ and...
Abreu, P, Adam, W, Adye, T, Adzic, P, Ajinenko, I, Alekseev, G D, ...
From a data sample of $9.98 {\mathrm{~pb^{-1}}}$ integrated luminosity collected by DELPHI at a centre-of-mass energy of 172 GeV, 118 events were selected as W-pair candidates. From these, the...
Measurement of the inclusive charmless and double-charm B branching ratios (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The DELPHI experiment at LEP has measured the inclusive charmless $B$ hadron decay branching ratio, the $B$ branching ratio into two charmed particles, and the total number of charmed particles per...
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From a data sample of $9.98 {\mathrm{~pb^{-1}}}$ integrated luminosity collected by DELPHI at a centre-of-mass energy of 172 GeV, 118 events were selected as W-pair candidates. From these, the...
Measurement of the charged particle multiplicity of weakly decaying B hadrons (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From the $Z$ decays recorded in 1994 and 1995 by the DELPHI detector at LEP, the charged particle multiplicity of weakly decaying $B$ hadrons was measured to be: \begin{center} $4.97 \pm 0.03 \pm...
A study of the hadronic resonance structure in the decay $\tau \rightarrow 3 \pi \nu_{\tau}$ (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The hadronic structure of the decay of the $\tau$ lepton to three charged particles, $\tau\rightarrow 3\pi\nu_\tau$, is studied using data collected by the DELPHI detector at LEP between 1992 and...
Investigation of the splitting of quark and gluon jets (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
Measurement of Trilinear Gauge Couplings in $e^+ e^-$ Collisions at 161 GeV and 172 GeV (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
Trilinear gauge boson couplings are measured using data taken by DELPHI at 161~GeV and 172~GeV. Values for $WWV$ couplings ($V=Z, \gamma$) are determined from a study of the reactions \eeWW\ and...
Investigation of the splitting of quark and gluon jets (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
Measurement of Trilinear Gauge Couplings in $e^+ e^-$ Collisions at 161 GeV and 172 GeV (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
Trilinear gauge boson couplings are measured using data taken by DELPHI at 161~GeV and 172~GeV. Values for $WWV$ couplings ($V=Z, \gamma$) are determined from a study of the reactions \eeWW\ and...
Measurement of the charged particle multiplicity of weakly decaying B hadrons (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From the $Z$ decays recorded in 1994 and 1995 by the DELPHI detector at LEP, the charged particle multiplicity of weakly decaying $B$ hadrons was measured to be: \begin{center} $4.97 \pm 0.03 \pm...
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From a data sample of $9.98 {\mathrm{~pb^{-1}}}$ integrated luminosity collected by DELPHI at a centre-of-mass energy of 172 GeV, 118 events were selected as W-pair candidates. From these, the...
Measurement of the inclusive charmless and double-charm B branching ratios (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The DELPHI experiment at LEP has measured the inclusive charmless $B$ hadron decay branching ratio, the $B$ branching ratio into two charmed particles, and the total number of charmed particles per...
A study of the hadronic resonance structure in the decay $\tau \rightarrow 3 \pi \nu_{\tau}$ (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The hadronic structure of the decay of the $\tau$ lepton to three charged particles, $\tau\rightarrow 3\pi\nu_\tau$, is studied using data collected by the DELPHI detector at LEP between 1992 and...
Investigation of the splitting of quark and gluon jets (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
Measurement of Trilinear Gauge Couplings in $e^+ e^-$ Collisions at 161 GeV and 172 GeV (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
Trilinear gauge boson couplings are measured using data taken by DELPHI at 161~GeV and 172~GeV. Values for $WWV$ couplings ($V=Z, \gamma$) are determined from a study of the reactions \eeWW\ and...
Measurement of the charged particle multiplicity of weakly decaying B hadrons (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From the $Z$ decays recorded in 1994 and 1995 by the DELPHI detector at LEP, the charged particle multiplicity of weakly decaying $B$ hadrons was measured to be: \begin{center} $4.97 \pm 0.03 \pm...
Abreu, P., Adam, W., Adye, T., Adzic, P., Ajinenko, I., Alekseev, G D., ...
From a data sample of $9.98 {\mathrm{~pb^{-1}}}$ integrated luminosity collected by DELPHI at a centre-of-mass energy of 172 GeV, 118 events were selected as W-pair candidates. From these, the...
Measurement of the inclusive charmless and double-charm B branching ratios (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The DELPHI experiment at LEP has measured the inclusive charmless $B$ hadron decay branching ratio, the $B$ branching ratio into two charmed particles, and the total number of charmed particles per...
A study of the hadronic resonance structure in the decay $\tau \rightarrow 3 \pi \nu_{\tau}$ (1998)
Abreu, P., Adam, W., Adye, T., Adzic, P., Alekseev, G D., Alemany, R., ...
The hadronic structure of the decay of the $\tau$ lepton to three charged particles, $\tau\rightarrow 3\pi\nu_\tau$, is studied using data collected by the DELPHI detector at LEP between 1992 and...
There is now a large amount of real world data available from the internet that is suitable for analysis with graphics calculators which are powerful statistical tools. This paper looks at some...
There is now a large amount of real world data available from the internet that is suitable for analysis with graphics calculators which are powerful statistical tools. This paper looks at some...
There is now a large amount of real world data available from the internet that is suitable for analysis with graphics calculators which are powerful statistical tools. This paper looks at some...
GarciaSanchez, F, Fu, SQ, Pizzorno, G, Yin, LH, Krause, DS, ...
Pizzorno, G, Krause, D, Liang, J, Adams, E, Leffert, JJ, ...
Measurement of the W pair cross-section and of the W mass in e+ e- interactions at 172-GeV (1997)
DELPHI Collaboration, Abreu, P, Adam, W, Adye, T, Adzic, P, Ajinenko, I, ...
Spaces of Maps Into Classifying Spaces for Equivariant Crossed Complexes (1997)
Brown Golasi'nski Porter, R Brown, T Porter, A Tonks
We give an equivariant version of the homotopy theory of crossed complexes. The applications generalize work on equivariant Eilenberg-Mac Lane spaces, including the non abelian case of dimension 1,...
Meeting patient expectations in the cancer consultation (1997)
Brown, R., Dunn, S., Butow, P.
Background: Low scores on satisfaction measures may be anticipated when patients' expectations of the doctor are un met during the cancer consultation. We correlated discrepan cies between patient...
Detector for the linear collider: Baseline design for the conceptual design report (1996)
Aid, S, Andreazza, A, Bambade, P, Bardin, G, Barklow, T, Bartel, W, ...
Ion Sources, Operation and Development (1996)
Derenchuk, V., Brown, R., Kupper, R., Petri, H
This research was sponsored by the National Science Foundation Grant NSF PHY-9314783
Spaces of Maps Into Classifying Spaces for Equivariant Crossed Complexes (1996)
R. Brown, M. Golasinski, T. Porter, A. Tonks
We give an equivariant version of the homotopy theory of crossed complexes. The applications generalize work on equivariant Eilenberg-Mac Lane spaces, including the non abelian case of dimension 1,...
OCCUPATIONAL EXPOSURE TO PERMETHRIN DURING ITS USE AS A PUBLIC HYGIENE INSECTICIDE (1996)
Llewellyn, D. M., Brazier, A., Brown, R., Cocker, J., Evans, M. L., Hampton, J., ...
Permetbrin is an active ingredient found in many public hygiene insecticide products and exposure to it was assessed in a survey of 45 professional users. The exposures measured were over a wide...
Spaces of Maps Into Classifying Spaces for Equivariant Crossed Complexes (1995)
R. Brown, M. Golasinski, T. Porter, A. Tonks
We give an equivariant version of the homotopy theory of crossed complexes. The applications generalize work on equivariant Eilenberg-Mac Lane spaces, including the non abelian case of dimension 1,...
Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis (1994)
Sapp, P, Viaene, M K, Rosen, D, McKenna-Yasek, D, Haines, J, ...
Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron disease that is inherited as an autosomal dominant trait in approximately 10% of cases. Recently we and others identified several...
Paralytic shellfish poisons from Australian cyanobacterial blooms (1994)
Humpage, A R, Bretag, Allan, Brown, R, Baker, Peter, Nicholson, Brenton C, Steffensen, D A, ...
Aktiwiteitsgebaseerde koste en -bestuur benadering in finansiele instellings / (1994)
Skripsie (M.Econ.)--Randse Afrikaanse Universiteit, 1994.
Paralytic shellfish poisons from Australian cyanobacterial blooms (1994)
Humpage, A R, Bretag, Allan, Brown, R, Baker, Peter, Nicholson, Brenton C, Steffensen, D A, ...
Paralytic shellfish poisons from Australian cyanobacterial blooms (1994)
Humpage, A R, Bretag, Allan, Brown, R, Baker, Peter, Nicholson, Brenton C, Steffensen, D A, ...
Design Tradeoffs for Software-Managed TLBs (1993)
D. Nagle, R. Uhlig, T. Stanley, T. Mudge, S. Sechrest, R. Brown, ...
An increasing number of architectures provide virtual memory support through software-managed TLBs. However, software management can impose considerable penalties, which are highly dependent on the...
The Direct Recording Scales from Teaching aids at low cost (TALC) have been designed to overcome some of the deficiencies in present growth monitoring programmes. This is the full account of the...
Obituary for Razia Zaman and Shahanara Zaman Saroya (1992)
Dorsey, T., Bernstein, I., Brabec, K., Vaughan, Frizell L., Stewart, J., Brown, R., ...
Peer Reviewed
IUCF High Intensity Polarized Ion Source (1991)
Wedekind, M., Brown, R., Derenchuk, V., Ellison, T., Friesel, D., Hicks, J., ...
This research was sponsored by the National Science Foundation Grant NSF PHY-9314783
An automated measuring system for the antiproton accumulator magnets (1990)
Brown, R, Dorenbos, T, Frauchiger, M, Johnson, C D, Petty, L
Multipole fields in the antiproton accumulator magnet system (1990)
Autin, Bruno, Bellanger, A, Billinge, Roy, Brown, R, Johnson, C D, Jones, E, ...
Electron Cooling System Development (1989)
Ellison, T., Brown, R., Friesel, D.
This research was sponsored by the National Science Foundation Grant NSF PHY-9314783
Choo, K.H., Vissel, B., Brown, R., Filby, R.G., Earle, E.
We report a new subfamily of alpha satellite DNA (pTRA-2) which is found on all the human acrocentric chromosomes. The aiphoid nature of the cloned DNA was established by partial sequencing. Southern...
AN EVALUATED PROGRAMME OF RHEUMATOLOGY TRAINING FOR GENERAL PRACTITIONERS (1986)
GRAHAME, R., GIBSON, T., DALE, E., DALE, E., ANDERSON, J. A. D., BROWN, R., ...
The management of painful, upper-limb disorders by 34 general practitioners (GPs) was examined 3 months before and 3 months after personal instruction of GPs by a consultant rheumatologist. Tuition...
Brown, R., Pee, Ph., Dupuy, F., Kottis, Ph.
Starting from the temperature dependence of triplet exciton transport in the trap States of naphthalene-H8 in naphthalene-D8, we argue that below 5K, transport is predominantly coherent, being...
MIRACULOUS HELICITY RULES, BASES, AND AMPLITUDES FOR VECTOR BOSONS (1985)
We describe what we have learned in recent years about perturbation theory as a result of doing calculations for processes with gauge bosons.
Brown, R., Pee, Ph., Dupuy, F., Kottis, Ph.
Starting from the temperature dependence of triplet exciton transport in the trap States of naphthalene-H8 in naphthalene-D8, we argue that below 5K, transport is predominantly coherent, being...
MIRACULOUS HELICITY RULES, BASES, AND AMPLITUDES FOR VECTOR BOSONS (1985)
We describe what we have learned in recent years about perturbation theory as a result of doing calculations for processes with gauge bosons.
TIME REVERSAL INVARIANCE IN POLARIZED NEUTRON BETA DECAY (1984)
Bowles, T., Moses, J., Sunier, J., Brown, R., Lisowski, P., Mampe, W., ...
Measurements of the triple correlation [MATH] in polarized neutron beta decay provide a test of time reversal violation. An experiment that will substantially improve the current limits on this...
TIME REVERSAL INVARIANCE IN POLARIZED NEUTRON BETA DECAY (1984)
Bowles, T., Moses, J., Sunier, J., Brown, R., Lisowski, P., Mampe, W., ...
Measurements of the triple correlation [MATH] in polarized neutron beta decay provide a test of time reversal violation. An experiment that will substantially improve the current limits on this...
CAUSE OF DEATH IN RHEUMATOID ARTHRITIS (1984)
PRIOR, P., SYMMONS, D. P. M., SCOTT, D. L., BROWN, R., HAWKINS, C.F.
A series of 489 consecutive patients with definite or classical rheumatoid arthritis was followed for a mean of 11.2 years. Cohort-analysis of the series showed a three-fold increase in mortality...
TEMPERATURE DEPENDENCE OF MULTIPHONON ABSORPTION IN HIGHLY TRANSPARENT CUBIC ZIRCONIA (1981)
Bendow, B., Lipson, H., Brown, R., Marshall, R., Billard, D., Mitra, S.
We investigate multiphonon absorption in the three to five phonon regime of yttria-stabilized cubic zirconia, over an extended range of temperatures. The absorption vs. frequency curves at fixed...
THE EFFECT OF DISLOCATIONS ON THERMAL CONDUCTIVITY (1981)
Phonon scattering by the strain fields of deformed crystals is formulated in terms of the third order elastic constants. The thermal restivity due to dislocations is calculated. Theory and experiment...
TEMPERATURE DEPENDENCE OF MULTIPHONON ABSORPTION IN HIGHLY TRANSPARENT CUBIC ZIRCONIA (1981)
Bendow, B., Lipson, H., Brown, R., Marshall, R., Billard, D., Mitra, S.
We investigate multiphonon absorption in the three to five phonon regime of yttria-stabilized cubic zirconia, over an extended range of temperatures. The absorption vs. frequency curves at fixed...
THE EFFECT OF DISLOCATIONS ON THERMAL CONDUCTIVITY (1981)
Phonon scattering by the strain fields of deformed crystals is formulated in terms of the third order elastic constants. The thermal restivity due to dislocations is calculated. Theory and experiment...
AN ANALYSIS OF THE ROLE OF KINETIC MECHANISMS AFFECTING H2 + F2 LASER PERFORMANCE (1980)
Computer simulations of pulsed H2 + F2 chemical laser performance have been made with a comprehensive model of VRT relaxation mechanisms in HF. The study includes an in-depth analysis of the role of...
AN ANALYSIS OF THE ROLE OF KINETIC MECHANISMS AFFECTING H2 + F2 LASER PERFORMANCE (1980)
Computer simulations of pulsed H2 + F2 chemical laser performance have been made with a comprehensive model of VRT relaxation mechanisms in HF. The study includes an in-depth analysis of the role of...
Auditory speaker recognition : a theoretical and experimental study. (1980)
Thesis (Ph. D.)--University of Edinburgh, 1980.
In 1976 the Medical Board decided to change the registration system from perpetual to annual registration. An ad hoc committee was established in early 1977 to consider the possibility of conducting...
In 1976 the Medical Board decided to change the registration system from perpetual to annual registration. An ad hoc committee was established in early 1977 to consider the possibility of conducting...
In 1976 the Medical Board decided to change the registration system from perpetual to annual registration. An ad hoc committee was established in early 1977 to consider the possibility of conducting...
Implications of the Formation of the Graft Union for Organisation in the Intact Plant (1976)
The formation of a successful graft union depends on a complex series of interactions which take place between the cells of the stock and scion. As a result of these interactions processes which...
Development During Vegetative Growth in the Apical Region of the Shoot of Lupinus albus (1976)
This investigation was designed to show the nature of the development in terms of cell numbers and of rates of division that proceeds in the terminal region of the shoot during the vegetative phase...
The Fundamental Groupoid as a Topological Groupoid (1975)
Let X be a topological space. Then we may define the fundamental groupoid nX and also the quotient groupoid (nX)/N for N any wide, totally disconnected, normal subgroupoid N of nX (1). The purpose of...
Brown, R., Mikaelian, K., Gould, R.
At photon energies above 7.2 x 1020 eV, absorption by γ + γ' → 2 e+ + 2 e– dominates that from the lower-order process γ + γ' → e+ + e– for high-energy...
An Analysis of the Development of the Graft Union in Lycopersicon esculentum (1974)
LINDSAY, D. W., YEOMAN, M. M., BROWN, R.
An examination of the development of the graft union in tomato shows that the breaking weight increases in two phases over a period of 7 days. The first phase lasts for approximately 4 days and is...
The activation energies for step-diffusion of the F-centre and reorientation of FA(Na) and FA(Li)-centres in KCl are analysed theoretically. For each defect in both ground and first excited states,...
Effects of Mechanical Stress on the Plane of Cell Division in Developing Callus Cultures (1971)
The imposition of abnormal stresses by culturing tissue explants in a bent configuration produces changes in the rate of cell accumulation and in the plane of cell division. The relief of stress by...
Groupoids and van Kampen’s theorem (1967)
The fundamental groupoid TT(X) of a topological space X has been known for a long time but has been regarded, usually, as of little import in comparison with the fundamental group—for example, the...
Printed in Great Britain Two examples in homotopy theory (1966)
The examples are unconnected. 1. According to some published footnotes, examples are known of Serre fibrations which are not Hurewicz fibrations. However, as far as I know no such example has been...
Cohomology with chains as coefficients (1964)
THE cohomology theory described in the title is obtained by replacing the usual coefficient group by an arbitrary chain complex. This theory satisfies all of the Eilenberg-Steenrod axioms for a...
The Effect of 2-thiouracil on the Growth of Cells in the Root (1963)
Observations have been made with either intact seedling roots or segments of roots of Pea (Vicia faba Meteor) and Maize (Zea mais American yellow horsetooth). Thiouracil, uracil and orotic acid were...
Printed in Great Britain On Kunneth suspensions (1963)
0. Introduction. In (2) we denned the Kunneth suspension of a cohomology operation —the Kunneth suspension involves an arbitrary ess-complex Y rather than the 1-sphere S 1, as with the usual...
The Development of the Graft Union (1961)
In this paper a new method is described for the examination of graft formation. The method depends in principle on the measurement of the tensile strength of the graft at intervals of 2 days. It has...
The Growth of the Isolated Root in Culture (1959)
This paper presents a discussion of the condition that control changes in the rate of division in the apex of the root. Date published earlier indicate three phases in the change in the total number...
The Nuclear Incorporation of Iron and its Significance in Growth (1958)
Pea roots were grown in solutions containing low concentrations of Fe59 and using the technique of autoradiography the intracellular incorporation of the labelled iron into sections of these roots...
Protein and Respiration in the Apical Region of the Shoot of Lupinus albus (1957)
SUNDERLAND, N., HEYES, J. K., BROWN, R.
This investigation is a study of differentiation in the apical region of the shoot in terms of the protein content and respiration of the dome and of each of the first seven primordia and...
Enzyme Changes in Relation to Cell Growth in Excised Root Tissues1 (1954)
Serial sections 1�0 mm. in length taken from the tip towards the base of the bean root have been cultured on 2 per cent, sucrose. At various time-intervals, length, invertase, phosphatase, and...
The Effects of Thiamin and Nicotinic Acid on Meristematic Activity in Pea Roots (1953)
The results of experiments with isolated pea roots are presented which show the effects on growth of providing nicotinic acid and thiamin in the medium. Certain of the experiments involve two...
The Absorption of Potassium by Cells in the Apex of the Root (1953)
The purpose of this investigation is the study of the properties of the cell with regard to potassium absorption as the cell expands. Serial sections each 1·5 mm. in length have been cut along the...
The Influence of Mature Tissue 2 (1952)
Observations have been made on rates of increase in total number of cells and on rates of division in isolated pea roots grown in sterile conditions in one series over a period of 9 days and in...
The Development of the Enzyme Complement in Growing Root Cells (1952)
Fifteen serial sections, each 1.0 mm. in length, have been taken from the tip towards the base of the bean root. On corresponding groups of sections determinations have been made of water content,...
A new technique for determining the durations of the different phases of division is described. It is shown that at 15� C. the mean durations of the several phases in the root-tip of the pea are as...
The Development of Cells in the Growing Zones of the Root (1950)
Data are presented which show the change in volume, dry weight, respiration, and protein content of the cell during development from the meristematic to the mature fully extended state. The data...
The Effects of Sugar and Potassium on Extension Growth in the Root (1950)
A new technique for studying extension growth in the root is described which is based on excising a zone which extends 1·5–3·0 mm. from the tip. Large numbers of these segments are cultured with...
Methadone: applied pharmacology and use as adjunctive treatment in chronic pain
Brown, R, Kraus, C, Fleming, M, Reddy, S
This article reviews the unique pharmacological properties of methadone and outlines its appropriate clinical application, with focus upon its use in the treatment of chronic pain. Although methadone...
Clinic blood pressure measurements and blood pressure load in the diagnosis of hypertension.
Lee, D. R., Sivakumaran, P., Brown, R.
We have retrospectively compared the blood pressure load derived from 24 hour ambulatory blood pressure monitoring in patients with all clinic blood pressure readings elevated with those with only...
Campylobacter enteritis in Chelmsford.
Bradshaw, M. J., Brown, R., Swallow, J. H., Rycroft, J. A.
During one year, out of 1829 faecal specimens examined at the Chelmsford Public Health Laboratory, campylobacters were isolated from 109 (6%), 21 of the positive cultures were from hospital...
Failure in community care. Supervision register needs rethinking.
O'Connor, S., Birkett, P., Parker, J., Dedman, P., Mumford, D., Brown, R., ...
MailMinder: taming DHCP's mailman interface.
Shultz, E. K., Brown, R., Kotta, G.
While the Department of Veteran's Affairs Decentralized Hospital Computer Program (DHCP) is one of the most widely disseminated and successful hospital information systems in existence, it currently...
Campanile, D., Nambiar, C.G., Bishop, P., Widdowson, M., Brown, R.
The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic...
Stearns, V, Jacobs, L, Khouri, N, Jeter, S, Powers, P, Shahverdi, K, ...
Cisplatin-DNA damage recognition proteins in human tumour extracts.
Bissett, D., McLaughlin, K., Kelland, L. R., Brown, R.
Enhanced repair of DNA adducts may be a cause of cis-diamminedichloroplatinum(II) resistance in solid malignancies. Binding of specific damage recognition proteins to the sites of DNA damage may be...
Coutts, J., Plumb, J. A., Brown, R., Keith, W. N.
Human topoisomerase II enzymes are targets for a number of widely used anticancer agents. We have analysed a lung adenocarcinoma cell line CALU3, which has co-amplified topoisomerase II alpha and...
Retrovirus mediated transfer and expression of GM-CSF in haematopoietic cells.
Keith, W. N., Brown, R., Pragnell, I. B.
Two retrovirus vectors were compared for their ability to express granulocyte-macrophage colony stimulating factor (GM-CSF) in a haematopoietic cell line, FDCP1, which is dependent on GM-CSF for...
Expression of mdr1 and gst-pi in human breast tumours: comparison to in vitro chemosensitivity.
Keith, W. N., Stallard, S., Brown, R.
Increased expression of the mdr1 gene, encoding the 175 kDa P-glycoprotein, and the gst-pi gene, encoding the anionic isozyme of glutathione S-transferase (GST), have previously been detected in...
Atopy--a favourable prognostic factor for survival in Hodgkin's disease.
Amlot, P. L., Slaney, J., Brown, R.
One hundred and forty-eight patients with Hodgkin's disease (HD) were stratified into 4 groups according to atopic status. Group 1 had a personal history of atopy and Group 2 a family history of...
Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors.
We have previously shown that loss of p53 function in A2780 human ovarian adenocarcinoma cells confers increased clonogenic resistance to several DNA-damaging agents, but not to taxol or...
De Graeff, P, Hall, J, Crijns, A P G, De Bock, G H, Paul, J, Oien, K A, ...
The prognostic impact of p53 immunostaining in a large series of tumours from epithelial ovarian cancer patients in a two-centre study was analysed. The study population (n=476) comprised of a...
Epigenetics as a mechanism driving polygenic clinical drug resistance
Glasspool, R M, Teodoridis, J M, Brown, R
Aberrant methylation of CpG islands located at or near gene promoters is associated with inactivation of gene expression during tumour development. It is increasingly recognised that such...
Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents
Colella, G, Marchini, S, D'Incalci, M, Brown, R, Broggini, M
p53 alterations in recurrent squamous cell cancer of the head and neck refractory to radiotherapy
Ganly, I, Soutar, D S, Brown, R, Kaye, S B
The aim of the study was to determine the incidence of p53 alterations by mutation, deletion or inactivation by mdm2 or human papillomavirus (HPV) infection in recurrent squamous cell cancer of the...