R. Fischer

Publication List Details

Period

1971 - 2008

Number

731

Co-Authors

Visual Physics Analysis (VISPA) - Concepts and First Applications (2008)

Actis, O., Erdmann, M., Fischer, R., Hinzmann, A., Kirsch, M., Klimkovich, T., ...

VISPA is a novel development environment for high energy physics analyses, based on a combination of graphical and textual steering. The primary aim of VISPA is to support physicists in prototyping,...

Small cleavable adapters enhance the specific cytotoxicity of a humanized immunotoxin directed against CD64-positive cells (2008)

Hetzel, C., Bachran, C., Fischer, R., Fuchs, H., Barth, S., Stocker, M.

The most potent immunotoxins (ITs) developed to date contain bacterial or plant cytotoxic components. As these are potentially immunogenic in man, human proteins are preferred for the long-term...

Generation and evaluation of movement protein-specific single-chain antibodies for delaying symptoms of Tomato spotted wilt virus infection in tobacco (2008)

Zhang, M.Y., Zimmermann, S., Fischer, R., Schillberg, S.

This study investigated whether single-chain antibodies (scFvs) specific for a viral movement protein could accumulate in the plant cell cytosol and restrict viral systemic infection in plants. Nine...

Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes (2008)

Stahnke, B., Thepen, T., Stöcker, M., Rosinke, R., Jost, E., Fischer, R., ...

Acute myeloid leukemia (AML) cells of subtypes M4 and M5 show enhanced expression of CD64 (Fc gamma RI), the high-affinity receptor for IgG, which is normally expressed at high levels only on...

Investigations on different positions of electrodes and their effects on the distribution of Cr at the water sediment interface (2007)

Shrestha, R., Fischer, R., Sillanpää, M.

In most mining areas, significant concentrations of metals such as Pb, Cu, Cr, Zn, Cd, Fe, Mn, Co, Ni, Hg, Ar, halogenated organic compounds and radionuclides are found. Of those, Cr is one of the...

Nichtlineares Vorcodierungsverfahren fuer einen digitalen Broadcastkanal (2007)

Fischer, R., Windpassinger, C.

WO2005011219 A UPAB: 20050311 NOVELTY - The non-linear precoding method uses a modulo arithmetic calculation for pre-equalizing of the broadcast channel (BC), with virtual division of the latter for...

Immunodetection of Venturia inaequalis ascospores with phage antibodies (2007)

Ribbert, M., Wolters, A., Barth, S., Stöcker, M., Schaeffer, A., Fischer, R., ...

We describe the bacterial expression of single chain variable fragment (scFv) antibodies that bind specifically to the ascospores of Venturia inaequalis (Cooke). A scFv phage display library was...

Genetic stability of recombinant potato virus X virus vectors presenting foreign epitopes (2007)

Uhde-Holzem, K., Fischer, R., Commandeur, U.

We investigated the genetic stability of recombinant potato virus X vectors presenting beet necrotic yellow vein virus (BNYVV) epitopes. Following N-terminal PVX coat protein (CP) fusion of the BNYVV...

Optimization of human papillomavirus type 16 (HPV-16) L1 expression in plants: Comparison of the suitability of different HPV-16 L1 gene variants and different cell-compartment localization (2007)

MacIean, J., Koekemoer, M., Oliver, A.J., Stewart, D., Hitzeroth, I. I., Rademacher, T., ...

Virus-like particle-based vaccines for high-risk human papillomaviruses (HPVs) appear to have great promise; however, cell culture-derived vaccines will probably be very expensive. The optimization...

Functional analysis of the broadly neutralizing human anti-HIV-1 antibody 2F5 produced in transgenic BY-2 suspension cultures (2007)

Sack, M., Paetz, A., Kunert, R., Bomble, M., Hesse, F., Stiegler, G., ...

We report the production of an important human therapeutic antibody in plant cell suspension cultures and the functional analysis of that antibody, including a comparison with the same antibody...

Design of protein-membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V (2007)

Segers, K., Sperandio, O., Sack, M., Fischer, R., Miteva, M.A., Rosing, J., ...

Most orally bioavailable drugs on the market are competitive inhibitors of catalytic sites, but a significant number of targets remain undrugged, because their molecular functions are believed to be...

Investigations on different positions of electrodes and their effects on the distribution of Cr at the water sediment interface (2007)

R. Shrestha, R. Fischer, M. Sillanpää

In most mining areas, significant concentrations of metals such as Pb, Cu, Cr, Zn, Cd, Fe, Mn, Co, Ni, Hg, Ar, halogenated organic compounds and radionuclides are found. Of those, Cr is one of the...

Spatial and temporal regulation of the forisome gene for1 in the phloem during plant development (2007)

Noll, G.A., Fontanellaz, M.E., Rüping, B., Ashoub, A., Fischer, R., ...

Forisomes are protein aggregates found uniquely in the sieve elements of Fabaceaen plants. Upon wounding they undergo a reversible, calcium-dependent conformational switch which enables them to act...

A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. (2007)

Duchardt, F, Fotin-Mleczek, M., Schwarz, Heinz, Fischer, R, Brock, R.

The plasma membrane represents an impermeable barrier for most macromolecules. Still some proteins and so-called cell-penetrating peptides enter cells efficiently. It has been shown that endocytosis...

The New SQUID Biosusceptometer at Oakland: First Year of Experience (2006)

EB Fung, R Fischer, Z Pakbaz, RL Fagaly, E Vichinsky, TN Starr, ...

Liver iron measurements using biosusceptometers have been validated on two low-TC SQUID (Superconducting Quantum Interference Device) systems (New York and Hamburg) built in the 1980’s. Recently,...

Interaction of Artificial Metallic Objects with Biosusceptometric Measurements (2006)

R Engelhardt, EB Fung, P Kelly, TR Biehl, Z Pakbaz, P Nielsen, ...

In human subjects, metallic objects cause distortions of the magnetic fields used by magnetic resonance imaging (0.5 – 3.0 T) or by SQUID biomagnetic liver susceptometry (0.1 – 30 mT) and may...

Interaction of Artificial Metallic Objects with Biosusceptometric Measurements (2006)

R Engelhardt, EB Fung, P Kelly, TR Biehl, Z Pakbaz, P Nielsen, ...

In human subjects, metallic objects cause distortions of the magnetic fields used by magnetic resonance imaging (0.5 – 3.0 T) or by SQUID biomagnetic liver susceptometry (0.1 – 30 mT) and may...

The New SQUID Biosusceptometer at Oakland: First Year of Experience (2006)

EB Fung, R Fischer, Z Pakbaz, RL Fagaly, E Vichinsky, TN Starr, ...

Liver iron measurements using biosusceptometers have been validated on two low-TC SQUID (Superconducting Quantum Interference Device) systems (New York and Hamburg) built in the 1980’s. Recently,...

The New SQUID Biosusceptometer at Oakland: First Year of Experience (2006)

EB Fung, R Fischer, Z Pakbaz, RL Fagaly, E Vichinsky, TN Starr, ...

Liver iron measurements using biosusceptometers have been validated on two low-TC SQUID (Superconducting Quantum Interference Device) systems (New York and Hamburg) built in the 1980’s. Recently,...

Interaction of Artificial Metallic Objects with Biosusceptometric Measurements (2006)

R Engelhardt, EB Fung, P Kelly, TR Biehl, Z Pakbaz, P Nielsen, ...

In human subjects, metallic objects cause distortions of the magnetic fields used by magnetic resonance imaging (0.5 – 3.0 T) or by SQUID biomagnetic liver susceptometry (0.1 – 30 mT) and may...

Mast Cell Growth Factor (C-Kit Ligand) in Combination with Granulocytemacrophage Colony-Stimulating Factor and Interleukin-3: In Vivo Hemopoietic Effects in Irradiated Mice Compared to in Vitro Effects (2006)

Patchen, M. L., Fischer, R., MacVittie, T. J., Seiler, F. R., Williams, D. E.

In the presence of hemopoietic cytokines such as granulocyte- macrophage colony-stimulating factor (GM-CSF) and interleukin-3 (IL-3), mast cell growth factor (MGF; also known as steel factor, stem...

Mast Cell Growth Factor Enhances Multilineage Hematopoietic Recovery in Vivo Following Radiation-Induced Aplasia (2006)

Patchen, M. L., Fischer, R., Schmauder-Chock, E. A., Williams, D. E.

Based on in vitro studies, mast cell growth factor (MGF; also known as steel factor, stem cell factor, and c-kit ligand) has been implicated as an important hematopoietic regulator, especially in the...

Single and Combination Cytokine Therapies for Treatment of Radiation- Induced Hematopoietic Injury: Effects of c-kit Ligand and Interleukin-3 (2006)

Patchen, M. L., Fischer, R., Macvittie, T. J., Seiler, F., Williams, D. E.

One of the most recent cytokines implicated in hematopoietic regulation is c-kit ligand, also known as mast cell growth factor (MGF), steel factor (SLF), and stem cell factor (SCF) (1-3). The c-kit...

Reactions to geovisualization: An experience from a European project (2006)

Andrienko, G., Andrienko, N., Fischer, R., Mues, V., Schuck, A.

The paper is written jointly by two parties, computer scientists specializing in geovisualization and experts in forestry, who cooperated within a joint project. The authors tell a story about an...

How repeated epiphylly correlates with gene expression of resident knox1 in the leaves of tobacco epiphyllous shoots (2006)

Müller, K.J., Lin, J., Fischer, R., Prüfer, D.

The tobacco knox1 genes tokn1 and tokn2 were isolated and their neomorphic capacities were tested while expressed in tobacco and potato. In addition, their neomorphic capacities were compared to...