R. G. Harvey

Publication List Details

Period

1973 - 1973

Number

24

Co-Authors

Splicing mutations in the CHO DHFR gene preferentially induced by (+/-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene.

Carothers, A M, Urlaub, G, Mucha, J, Harvey, R G, Chasin, L A, Grunberger, D

Cultured Chinese hamster ovary (CHO) cells were treated with the polycyclic aromatic hydrocarbon racemic 3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene....

Illegitimate recombination induced by benzo[a]pyrene diol epoxide in Escherichia coli.

Kokontis, J M, Vaughan, J, Harvey, R G, Weiss, S B

Duplex DNA oligomer constructs (32 base pairs) were prepared that contained a single benzo[a]pyrene (BP) adduct at a specific deoxyadenosine or deoxyguanosine site in either one or both strands....

Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide.

Xu, R, Birke, S, Carberry, S E, Geacintov, N E, Swenberg, C E, Harvey, R G

The unwinding of supercoiled phi X174 RFI DNA induced by the tumorigenic (+) and non-tumorigenic (-) enantiomers of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) has...

Effect of benzo[a]pyrene-diolepoxide on infectivity and in vitro translation of phage MS2 RNA.

Sagher, D, Harvey, R G, Hsu, W T, Weiss, S B

Previous studies have shown that alkylation of MS2 RNA by certain derivatives of polycyclic aromatic hydrocarbons renders it noninfectious. Since phage RNA serves as a template for translation and...

Use of short DNA oligonucleotides for determination of DNA sequence modifications induced by benzo[a]pyrene diol epoxide.

Wei, S J, Desai, S M, Harvey, R G, Weiss, S B

Various organic agents that alkylate DNA are known to induce mutations in bacterial and animal cells. The precise nature and location of modified DNA sequences in such mutants are often difficult to...

Structure of 7,12-dimethylbenz(a)anthracene-guanosine adducts.

Jeffrey, A M, Blobstein, S H, Weinstein, I B, Beland, F A, Harvey, R G, Kasai, H, ...

Arene oxides have been proposed as the reactive intermediates in the process of carcinogenesis induced by polycyclic aromatic hydrocarbons. The present study defines the structures of four guanosine...

(+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.

King, H W, Osborne, M R, Beland, F A, Harvey, R G, Brookes, P

The addition of borate buffer to the aqueous methanol used to elute hydrocarbon-deoxyribonucleoside derivatives from an LH 20 Sephadex column resulted in the separation of the products of reaction...

A bacteriophage system for screening and study of biologically active polycyclic aromatic hydrocarbons and related compounds.

Hsu, W T, Harvey, R G, Lin, E J, Weiss, S B

The usefulness of bacterial viruses for detecting substances that are potentially carcinogenic is reexamined as a model system for screening biologically active polycyclic aromatic hydrocarbons. A...

Mechanism of phage phiX174 DNA inactivation by benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide.

Hsu, W T, Lin, E J, Harvey, R G, Weiss, S B

A previous report from this laboratory has shown that certain derivatives of polycyclic aromatic hydrocarbons bind to phiX174 DNA and render it noninfectious. The present work describes the...

Splicing mutations in the CHO DHFR gene preferentially induced by (+/-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene.

Carothers, A M, Urlaub, G, Mucha, J, Harvey, R G, Chasin, L A, Grunberger, D

Cultured Chinese hamster ovary (CHO) cells were treated with the polycyclic aromatic hydrocarbon racemic 3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene....

Illegitimate recombination induced by benzo[a]pyrene diol epoxide in Escherichia coli.

Kokontis, J M, Vaughan, J, Harvey, R G, Weiss, S B

Duplex DNA oligomer constructs (32 base pairs) were prepared that contained a single benzo[a]pyrene (BP) adduct at a specific deoxyadenosine or deoxyguanosine site in either one or both strands....

Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide.

Xu, R, Birke, S, Carberry, S E, Geacintov, N E, Swenberg, C E, Harvey, R G

The unwinding of supercoiled phi X174 RFI DNA induced by the tumorigenic (+) and non-tumorigenic (-) enantiomers of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) has...

Effect of benzo[a]pyrene-diolepoxide on infectivity and in vitro translation of phage MS2 RNA.

Sagher, D, Harvey, R G, Hsu, W T, Weiss, S B

Previous studies have shown that alkylation of MS2 RNA by certain derivatives of polycyclic aromatic hydrocarbons renders it noninfectious. Since phage RNA serves as a template for translation and...

Use of short DNA oligonucleotides for determination of DNA sequence modifications induced by benzo[a]pyrene diol epoxide.

Wei, S J, Desai, S M, Harvey, R G, Weiss, S B

Various organic agents that alkylate DNA are known to induce mutations in bacterial and animal cells. The precise nature and location of modified DNA sequences in such mutants are often difficult to...

Structure of 7,12-dimethylbenz(a)anthracene-guanosine adducts.

Jeffrey, A M, Blobstein, S H, Weinstein, I B, Beland, F A, Harvey, R G, Kasai, H, ...

Arene oxides have been proposed as the reactive intermediates in the process of carcinogenesis induced by polycyclic aromatic hydrocarbons. The present study defines the structures of four guanosine...

(+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.

King, H W, Osborne, M R, Beland, F A, Harvey, R G, Brookes, P

The addition of borate buffer to the aqueous methanol used to elute hydrocarbon-deoxyribonucleoside derivatives from an LH 20 Sephadex column resulted in the separation of the products of reaction...

A bacteriophage system for screening and study of biologically active polycyclic aromatic hydrocarbons and related compounds.

Hsu, W T, Harvey, R G, Lin, E J, Weiss, S B

The usefulness of bacterial viruses for detecting substances that are potentially carcinogenic is reexamined as a model system for screening biologically active polycyclic aromatic hydrocarbons. A...

Mechanism of phage phiX174 DNA inactivation by benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide.

Hsu, W T, Lin, E J, Harvey, R G, Weiss, S B

A previous report from this laboratory has shown that certain derivatives of polycyclic aromatic hydrocarbons bind to phiX174 DNA and render it noninfectious. The present work describes the...

A study of the human biology of two New Guinea populations

Harvey, R. G. (Robin Grant)

Published on demand by: Kensington, N.S.W. : University of New South Wales Library. Includes bibliography.