R. Geffers

Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury (2008)

Lamle, J., Marhenke, S., Borlak, J., Wasielewski, R. Von, Eriksson, C.J.P., Geffers, R., ...

Background & Aims: The transcription factor nuclear factor-eythroid 2-related factor 2 (Nrf2(-/-)) is essential for protecting cells against xenobiotic and oxidative stress. Increased oxidative...

Argyrin a reveals a critical role for the tumor suppressor protein p27kip1 in mediating antitumor activities in response to proteasome inhibition. (2008)

Nickeleit, I., Zender, S., Sasse, E., Geffers, R., Brandes, G., Soerensen, I., ...

A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14 (2007)

Bohn, G., Allroth, A., Brandes, G., Thiel, J., Glocker, E., Schäffer, A.A., ...

Lysosome-related organelles have versatile functions, including protein and lipid degradation, signal transduction and protein secretion. The molecular elucidation of rare congenital diseases...

Virulence profiling of Streptococcus dysgalactiae subspecies equisimilis isolated from infected humans reveals 2 distinct genetic lineages that do not segregate with their phenotypes or propensity to cause diseases (2007)

Davies, M. R., McMillan, D. J., Beiko, R. G., Barroso, V, Geffers, R, Sriprakash, K. S., ...

Background. In spite of the emerging importance of Streptococcus dysgalactiae subspecies equisimilis (human group C streptococci [GCS] and group G streptococci [GGS]) in human health, its molecular...

Virulence profiling of Streptococcus dysgalactiae subspecies equisimilis isolated from infected humans reveals 2 distinct genetic lineages that do not segregate with their phenotypes or propensity to cause diseases (2007)

Davies, M. R., McMillan, D. J., Beiko, R. G., Barroso, V, Geffers, R, Sriprakash, K. S., ...

Background. In spite of the emerging importance of Streptococcus dysgalactiae subspecies equisimilis (human group C streptococci [GCS] and group G streptococci [GGS]) in human health, its molecular...

Genes for the majority of group A streptococcal virulence factors and extracellular surface proteins do not confer an increased propensity to cause invasive disease (2006)

McMillan, D. J., Beiko, G. R., Geffers, R., Buer, J., Schouls, M., Vlaminckx, B. J. M., ...

Background. The factors behind the reemergence of severe, invasive group A streptococcal (GAS) diseases are unclear, but it could be caused by altered genetic endowment in these organisms. However,...

Genes for the majority of group A streptococcal virulence factors and extracellular surface proteins do not confer an increased propensity to cause invasive disease (2006)

McMillan, D. J., Beiko, G. R., Geffers, R., Buer, J., Schouls, M., Vlaminckx, B. J. M., ...

Background. The factors behind the reemergence of severe, invasive group A streptococcal (GAS) diseases are unclear, but it could be caused by altered genetic endowment in these organisms. However,...

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells (2005)

Czuchra,A., Wu,X. W., Meyer,H., Van Hengel,J., Schroeder,T., Geffers,R., ...

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells (2005)

Czuchra, A., Wu, X. W., Meyer, H., Van Hengel, J., Schroeder, T., Geffers, R., ...

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells (2005)

CZUCHRA, A, WU, XW, MEYER, H, Van Hengel, Jolanda, SCHROEDER, T, GEFFERS, R, ...

TRANSFAC(R): transcriptional regulation, from patterns to profiles (2003)

Matys, V., Fricke, E., Geffers, R., Gößling, E., Haubrock, M., Hehl, R., ...

The TRANSFAC® database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed,...

The TRANSFAC system on gene expression regulation (2001)

Wingender, E., Chen, X., Fricke, E., Geffers, R., Hehl, R., Liebich, I., ...

The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of...

Organization as author and publisher Institute of Medicine (US). Looking at the future of the Medicaid program (1992)

V. Matys, E. Fricke, R. Geffers, E. Gößling, M. Haubrock, R. Hehl, ...

The TRANSFAC 1 database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed,...

The TRANSFAC system on gene expression regulation

Wingender, E., Chen, X., Fricke, E., Geffers, R., Hehl, R., Liebich, I., ...

The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules....

TRANSFAC®: transcriptional regulation, from patterns to profiles

Matys, V., Fricke, E., Geffers, R., Gößling, E., Haubrock, M., Hehl, R., ...

The TRANSFAC® database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed,...

The TRANSFAC system on gene expression regulation

Wingender, E., Chen, X., Fricke, E., Geffers, R., Hehl, R., Liebich, I., ...

The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules....

TRANSFAC®: transcriptional regulation, from patterns to profiles

Matys, V., Fricke, E., Geffers, R., Gößling, E., Haubrock, M., Hehl, R., ...

The TRANSFAC® database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed,...

CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation

Westendorf, A M, Templin, M, Geffers, R, Deppenmeier, S, Gruber, A D, Probst-Kepper, M, ...

Background: Several studies have suggested that chronic inflammatory bowel disease may be a consequence of antigen specific recognition by appropriate T cells which expand and induce immunopathology.