R. Gerli

Ultrasonography of salivary glands in primary Sjogren's syndrome: a comparison with contrast sialography and scintigraphy (2008)

Salaffi, F., Carotti, M., Iagnocco, A., Luccioli, F., Ramonda, R., Sabatini, E., ...

Objective. To compare ultrasonography (US) of salivary glands with contrast sialography and scintigraphy, in order to evaluate the diagnostic value of this method in primary SS (pSS). Methods. The...

Traditional cardiovascular risk factors in primary Sjogren's syndrome--role of dyslipidaemia (2006)

Gerli, R., Bartoloni Bocci, E., Vaudo, G., Marchesi, S., Vitali, C., Shoenfeld, Y.

Traditional cardiovascular risk factors in primary Sjogren's syndrome--role of dyslipidaemia (2006)

Gerli, R., Bartoloni Bocci, E., Vaudo, G., Marchesi, S., Vitali, C., Shoenfeld, Y.

Traditional cardiovascular risk factors in primary Sjogren's syndrome--role of dyslipidaemia (2006)

Gerli, R., Bartoloni Bocci, E., Vaudo, G., Marchesi, S., Vitali, C., Shoenfeld, Y.

The Diagnostic Utility of Anti-cyclic Citrullinated Peptide Antibodies, Matrix Metalloproteinase-3, Rheumatoid Factor, Erythrocyte Sedimentation Rate, and C-reactive Protein in Patients with Erosive and Non-erosive Rheumatoid Arthritis (2005)

O. Shovman, B. Gilburd, G. Zandman-Goddard, Y. Sherer, H. Orbach, R. Gerli, ...

Objective: To compare the diagnostic utility of laboratory variables, including matrix metalloproteinase-3 (MMP-3), anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor (RF),...

The Diagnostic Utility of Anti-cyclic Citrullinated Peptide Antibodies, Matrix Metalloproteinase-3, Rheumatoid Factor, Erythrocyte Sedimentation Rate, and C-reactive Protein in Patients with Erosive and Non-erosive Rheumatoid Arthritis (2005)

O. Shovman, B. Gilburd, G. Zandman-Goddard, Y. Sherer, H. Orbach, R. Gerli, ...

Objective: To compare the diagnostic utility of laboratory variables, including matrix metalloproteinase-3 (MMP-3), anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor (RF),...

Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus (2005)

Gambelunghe, G., Gerli, R., Bartoloni Bocci, E., Del Sindaco, P., Ghaderi, M., Sanjeevi, C. B., ...

Objective. To evaluate the contribution of the MHC class I chain-related A (MICA) gene polymorphism to the genetic risk of systemic lupus erythematosus (SLE). Methods. HLA-DRB1-DQA1-DQB1 genotyping,...

PP2. LONG-TERM FOLLOW-UP OF POLYMYALGIA RHEUMATICA PATIENTS TREATED WITH METHOTREXATE AND STEROIDS (2005)

Cimmino, M. A., Salvarani, C., Macchioni, L., Gerli, R., Delle Monache, F., Montecucco, C., ...

Introduction: We have recently demonstrated that combination therapy with prednisone and methotrexate (MTX) is effective as steroid-sparing treatment for patients with newly diagnosed polymyalgia...

Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus (2004)

Gambelunghe, G., Gerli, R., Bartoloni Bocci, E., Del Sindaco, P., Ghaderi, M., Sanjeevi, C. B., ...

Methods. HLA-DRB1-DQA1-DQB1 genotyping, MICA exon 5 microsatellite genotyping and HLA-B8 genotyping were performed in 48 Italian SLE patients and in 158 healthy control subjects. Results. Of HLA...

Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus (2004)

Gambelunghe, G., Gerli, R., Bartoloni Bocci, E., Del Sindaco, P., Ghaderi, M., Sanjeevi, C. B., ...

Methods. HLA-DRB1-DQA1-DQB1 genotyping, MICA exon 5 microsatellite genotyping and HLA-B8 genotyping were performed in 48 Italian SLE patients and in 158 healthy control subjects. Results. Of HLA...

Clinical and serological associations of ribosomal P autoantibodies in systemic lupus erythematosus: prospective evaluation in a large cohort of Italian patients: reply (2003)

Gerli, R., Caponi, L.

Unmasking the anti-inflammatory cytokine response in rheumatoid synovitis (2002)

Gerli, R., Lunardi, C., Pitzalis, C.

Clinical and serological associations of ribosomal P autoantibodies in systemic lupus erythematosus: prospective evaluation in a large cohort of Italian patients (2002)

Gerli, R., Caponi, L., Tincani, A., Scorza, R., Sabbadini, M. G., Danieli, M. G., ...

Objective. To verify the association of ribosomal anti‐P antibodies (anti‐P), as detected by a sensitive ELISA, with serological findings and clinical manifestations,...

Soluble CD30 in early rheumatoid arthritis as a predictor of good response to second-line therapy (1999)

Gerli, R., Bistoni, O., Lunardi, C., Giacomelli, R., Tomassini, C., Biagini, P., ...

Objective. To evaluate whether serum levels of the soluble form of CD30 (sCD30) correlate with disease activity in early rheumatoid arthritis (RA) and may have prognostic value in predicting the...

Quantitative assessment of salivary gland inflammatory infiltration in primary Sjogren's syndrome: its relationship to different demographic, clinical and serological features of the disorder (1997)

Gerli, R, Muscat, C, Giansanti, M, Danieli, MG, Sciuto, M, Gabrielli, A, ...

Basis for defective proliferation of peripheral blood T cells to anti-CD2 antibodies in primary Sjögren's syndrome.

Gerli, R, Bertotto, A, Agea, E, Lanfrancone, L, Cernetti, C, Spinozzi, F, ...

Anti-CD2-induced T cell proliferation was analyzed in the peripheral blood samples of 31 primary and 8 secondary untreated Sjögren's syndrome patients. Anti-CD2-stimulated PBMC proliferation was...

Basis for defective proliferation of peripheral blood T cells to anti-CD2 antibodies in primary Sjögren's syndrome.

Gerli, R, Bertotto, A, Agea, E, Lanfrancone, L, Cernetti, C, Spinozzi, F, ...

Anti-CD2-induced T cell proliferation was analyzed in the peripheral blood samples of 31 primary and 8 secondary untreated Sjögren's syndrome patients. Anti-CD2-stimulated PBMC proliferation was...

T-lymphocyte activation pathways in alcoholic liver disease.

Spinozzi, F, Bertotto, A, Rondoni, F, Gerli, R, Scalise, F, Grignani, F

Immune system derangement in cirrhotic patients with evidence of malnutrition is a well-recognized characteristic of chronic alcohol abuse. However, in vitro studies on cellular immune function...

Human milk lymphocytes bearing the gamma/delta T-cell receptor are mostly delta TCS1-positive cells.

Bertotto, A, Gerli, R, Castellucci, G, Scalise, F, Vaccaro, R

Our laboratories previously reported that the proportion of lymphocytes bearing the gamma/delta T-cell receptor (TcR) is twofold greater in human milk lymphocyte suspensions than in autologous and...

Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis.

Scalise, F, Gerli, R, Castellucci, G, Spinozzi, F, Fabietti, G M, Crupi, S, ...

Although the relative and absolute numbers of CD3+ cells (T lymphocytes) were similar in eight children with acquired Toxoplasma gondii infection and 10 uninfected age- and sex-matched healthy...

Long term treatment of rheumatoid arthritis with high doses of intravenous immunoglobulins: effects on disease activity and serum cytokines.

Muscat, C, Bertotto, A, Ercolani, R, Bistoni, O, Agea, E, Cesarotti, M, ...

OBJECTIVE--To evaluate the effects of long term treatment of rheumatoid arthritis (RA) with high doses of intravenous immunoglobulins (IVIg). METHODS--Ten patients with active RA and prior...

Assessment of the European classification criteria for Sjögren's syndrome in a series of clinically defined cases: results of a prospective multicentre study. The European Study Group on Diagnostic Criteria for Sjögren's Syndrome.

Vitali, C, Bombardieri, S, Moutsopoulos, H M, Coll, J, Gerli, R, Hatron, P Y, ...

OBJECTIVE: To assess the recently proposed preliminary criteria for the classification of Sjögren's syndrome (SS) in a multicentre European study of a new series of clinically defined cases....

Anti-ribosomal P protein antibodies detected by immunoblotting in patients with connective tissue diseases: their specificity for SLE and association with IgG anticardiolipin antibodies

Ghirardello, A, Doria, A, Zampieri, S, Gerli, R, Rapizzi, E, Gambari, P

OBJECTIVE—To assess the prevalence and clinical and serological associations of anti-ribosomal P protein antibodies (anti-P antibodies) in patients with connective tissue diseases (CTDs) and...

Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity

Vaudo, G, Marchesi, S, Gerli, R, Allegrucci, R, Giordano, A, Siepi, D, ...

Background: Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease. Endothelial dysfunction represents the earliest stage of atherosclerosis.

Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity

Vaudo, G, Marchesi, S, Gerli, R, Allegrucci, R, Giordano, A, Siepi, D, ...

Expression and functional role of 1F7 (CD26) antigen on peripheral blood and synovial fluid T cells in rheumatoid arthritis patients.

Muscat, C, Bertotto, A, Agea, E, Bistoni, O, Ercolani, R, Tognellini, R, ...

The expression and the functional role of the CD26 (1F7) T cell surface molecule, an ectoenzyme which seems to represent a functional collagen receptor of T lymphocytes and to have a role in T cell...

Analysis of CD4-positive T cell subpopulation in sarcoidosis.

Gerli, R, Darwish, S, Broccucci, L, Minotti, V, Spinozzi, F, Cernetti, C, ...

Double-labelling immunofluorescence analysis within the CD4+ cell subset was carried out in 27 bronchoalveolar lavage fluids and 11 peripheral blood samples of sarcoidosis patients with anti-TQ1,...

Reduced number of natural killer cells in patients with pathological hyperprolactinemia.

Gerli, R, Rambotti, P, Nicoletti, I, Orlandi, S, Migliorati, G, Riccardi, C

Human natural killer (NK) cell activity, as measured against K-562 target cells, was evaluated in 23 untreated and in 11 bromocriptine-treated hyperprolactinemic female patients and in 63 age-matched...

High levels of the soluble form of CD30 molecule in rheumatoid arthritis (RA) are expression of CD30+ T cell involvement in the inflamed joints.

Gerli, R, Muscat, C, Bistoni, O, Falini, B, Tomassini, C, Agea, E, ...

The CD30 is a surface molecule expressed by Th2-type lymphokine-producing T cells upon activation. CD30-expressing activated T cells release a soluble form of the molecule, which can be detectable...

The inhibitory effect of dexamethasone on lymphocyte adhesion molecule expression and intercellular aggregation is not mediated by lipocortin 1

Goulding, N J, Ogbourn, S, Pipitone, N, Biagini, P, Gerli, R, Pitzalis, C

Glucocorticoids exert their anti-inflammatory activity through multiple pathways which include the inhibition of cell adhesion events. The glucocorticoid-induced protein lipocortin 1 (LC1) has...

In vivo activated T cells in rheumatoid synovitis. Analysis of Th1- and Th2-type cytokine production at clonal level in different stages of disease

Gerli, R, Bistoni, O, Russano, A, Fiorucci, S, Borgato, L, Cesarotti, M E F, ...

T-cell cytokines play a crucial role in the pathogenesis and progression of rheumatoid arthritis (RA). Their detection in the joint, however, is impaired by the complex network present in the...

The Diagnostic Utility of Anti-cyclic Citrullinated Peptide Antibodies, Matrix Metalloproteinase-3, Rheumatoid Factor, Erythrocyte Sedimentation Rate, and C-reactive Protein in Patients with Erosive and Non-erosive Rheumatoid Arthritis

Shovman, O., Gilburd, B., Zandman-Goddard, G., Sherer, Y., Orbach, H., Gerli, R., ...

Objective: To compare the diagnostic utility of laboratory variables, including matrix metalloproteinase-3 (MMP-3), anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor (RF),...

T cell response to anti-CD3 antibody in Down's syndrome.

Bertotto, A, Arcangeli, C, Crupi, S, Marinelli, I, Gerli, R, Vaccaro, R

The non-specific mitogen phytohaemagglutinin (PHA) and an anti-CD3 (OKT3) monoclonal antibody were used to measure the lymphocyte proliferative response in blood samples from 15 subjects with Down's...