Kanani, M., Elliott, M.E., Cook, A., Juraszek, A., Devine, W., Anderson, R.H.
Objective: The mortality following repair of atrioventricular septal defects has fallen dramatically in the last 4 decades, but reoperation for late regurgitation across the left atrioventricular...
Two distinct pools of mesenchyme contribute to the development of the atrial septum (2006)
Mommersteeg, M.T.M., Soufan, A.T., Lange, F.J. De, Anderson, R.H., Christoffels, V.M., ...
Closure of the primary atrial foramen is achieved by fusion of the atrioventricular cushions with the mesenchymal cap on the leading edge of the muscular primary atrial septum. A fourth component...
Development and structures of the venous pole of the heart (2006)
Anderson, R.H., Brown, N.A., Moorman, A.F.M.
In the past, our interpretations of cardiac development depended on analysis of serially sectioned embryos, supported by three-dimensional reconstructions. It was not possible, using these...
Development of the atrioventricular valves: clinicomorphological correlations (2005)
Kanani, M., Moorman, A.F.M., Cook, A.C., Brown, N.A., Lamers, W.H., Anderson, R.H.
The Data Reconfiguration Service--An Experiment in Adaptable, Process/Process Communication, (2005)
Anderson,R. H., Cerf,V., Harslen,E. F., Heafner,J. F., Madden,J.
The nationwide ARPA Network is composed of different host computers at geographically separated sites that are interconnected by small, standardized computers (IMPs) and 50K-bit communication lines...
STRUCTURAL BEHAVIOR OF RING SECTIONS UNDER NONUNIFORM EXTERNAL PRESSURE. (2005)
Anderson, R. H., Haelsig, R. T., Reifel, M. D.
The purpose of this research was to develop methods of analysis and structural design for ring sections under a prescribed nonuniform external pressure distribution. This pressure distribution...
Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway (2004)
Bamforth, S.D., Bragança, J., Farthing, C.R., Schneider, J.E., Broadbent, C., Michell, A.C., ...
Malformations of the septum, outflow tract and aortic arch are the most common congenital cardiovascular defects and occur in mice lacking Cited2, a transcriptional coactivator of TFAP2. Here we show...
Soufan, A.T., Ruijter, J.M., Hagoort, J., Webb, S., ...
Lineage and morphogenetic analysis of the cardiac valves (2004)
Lange, F.J. De, Moorman, A.F.M., Anderson, R.H., Männer, J., Soufan, A.T., ...
Lineage and morphogenetic analysis of the cardiac valves (2004)
Lange, F.J. De, Moorman, A.F.M., Anderson, R.H., Männer, J., Soufan, A.T., ...
A New Approach to Programming Man Interfaces (2004)
Anderson, R. H., Sibley, W. L.
The report discusses the application of recent developments in web languages and machine learning of heuristics to problems in programming a flexible interface mechanism between a user and an...
Septation and separation within the outflow tract of the developing heart (2003)
Webb, S., Qayyum, S.R., Anderson, R.H., Lamers, W.H., Richardson, M.K.
Development of the heart: (1) - Formation of the cardiac chambers and arterial trunks (2003)
Moorman, A.F.M., Webb, S., Brown, N.A., Lamers, W.H., Anderson, R.H.
Development of the heart: (1) - Formation of the cardiac chambers and arterial trunks (2003)
Moorman, A.F.M., Webb, S., Brown, N.A., Lamers, W.H., Anderson, R.H.
Development of the heart: (1) - Formation of the cardiac chambers and arterial trunks (2003)
Moorman, A.F.M., Webb, S., Brown, N.A., Lamers, W.H., Anderson, R.H.
Massoudy, P., Baltalarli, A., De Leval, M.R., Cook, A., Neudorf, U., Derrick, G., ...
Background: We investigated the coronary arterial origins and course and the position of the great arteries in hearts with discordant ventriculoarterial connections. At the same time, we sought to...
Real-time three-dimensional fetal echocardiography - optimal imaging windows (2002)
Deng, J., Sullivan, I.D., Yates, R., Vogel, M., Mcdonald, D., Linney, A.D., ...
A total of 15 fetuses were scanned using 2-D array volumetric ultrasound (US). Acquired cardiac data were converted for rendering dynamic 3-D surface views and reformatting cross-sectional views. The...
Cabrera, J.A., Sánchez-Quintana, D., Farré, J., Navarro, F., Rubio, J.M., Cabestrero, F., ...
Background: Pulmonary vein isolation with radiofrequency catheter ablation techniques is used to prevent recurrences of human atrial fibrillation. Visualization of the architecture at the venoatrial...
Attitudinally correct nomenclature (2002)
For half a century, inappropriate terms have been used to describe the various parts of the heart in a clinical context. Does the cardiological community have the fortitude to correct these mistakes?
Rand Intelligent Terminal Agent (RITA): Design Philosophy, (2002)
Anderson,R. H., Gillogly,J. J.
The report presents a description of the design constraints, design requirements, and overall design philosophy guiding the implementation of the Rand Intelligent Terminal Agent (RITA). RITA is a set...
Anderson,R. H., Gallegos,Margaret, Gillogly,J. J., Greenberg,R., Villanueva,R.
A detailed reference manual for the RITA system, a set of computer programs which enable a user to develop user agents to perform such tasks as providing a simple interface to remote data systems....
Design of a Rule-Oriented System for Implementing Expertise. (2002)
Waterman, D. A., Anderson, R. H., Hayes-Roth, Frederick, Klahr, Philip, Martins, Gary
This Note describes the preliminary design of a Rule-Oriented System for Implementing Expertise (ROSIE). This system will serve as a tool for model builders seeking to apply expert knowledge to the...
Henderson, D.J., Conway, S.J., Greene, N.D.E., Gerrelli, D., Murdoch, J.N., Anderson, R.H., ...
Loop-tail (Lp) is a naturally occurring mouse mutant that develops severe neural tube defects. In this study, we describe complex cardiovascular defects in Lp homozygotes, which include double-outlet...
Mazgalev, T.N., Ho, S.Y., Anderson, R.H.
The remarkable success of radiofrequency ablation in recent decades in curing atrioventricular nodal reentrant tachycardias has intensified efforts to provide a solid theoretical basis for...
Echocardiographic and morphological correlations in tetralogy of Fallot (1999)
Gatzoulis, M.A., Soukias, N., Ho, S.Y., Josen, M., Anderson, R.H.
Aims Our aim was to clarify the location and structure of the outlet septum relative to the free-standing sub-pulmonary infundibulum in the setting of tetralogy of Fallot and to examine its...
AN ON-LINE SYMBOLIC MATHEMATICS SYSTEM USING HAND-PRINTED TWO-DIMENSIONAL NOTATION, (1998)
Blackwell,F. W., Anderson,R. H.
A description of a system being developed for the on-line manipulation of symbolic mathematical expressions is given. The user hand-prints his formulas, and the mathematical rules to be followed, on...
EXTENSIONS TO THE PL/I LANGUAGE FOR INTERACTIVE COMPUTER GRAPHICS, (1998)
The report presents a proposed combination of the IBM Conversational Programming System (CPS) and the Rand Programmer-Oriented Graphics Operation (POGO). CPS is entirely typewriter oriented and uses...
G,E. Bernal, Stokes,R. J., Koepke,B. G., Anderson,R. H.
The purpose of the program was to define methods of producing polycrystalline halide materials with improved mechanical properties while maintaining the desirable optical properties of the single...
Bernal G. ,E., Stokes,R. J., Koepke,B. G., Anderson,R. H.
The mechanisms of high temperature deformation of alkali halides are reviewed. It is shown that at high temperatures it is possible to deform these materials to an arbitrary shape without void...
Alkali Halide FLIR Lens Development. (1998)
Anderson,R. H., Stokes,R. J., Moravec,T. J., Lin,J. W., Schmit,F. M.
This report describes development of materials and processes for environmental protection of alkali halide lenses. The alkali halide lenses are fabricated by direct hot forging, which yields a...
Interventricular communication in complete atrioventricular septal defect (1998)
Suzuki, K., Ho, S.Y., Anderson, R.H., Becker, A.E., Neches, W.H., Tasuno, K., ...
Morphometric analysis of atrioventricular septal defect with common valve orifice (1998)
Suzuki, K., Ho, S.Y., Anderson, R.H., Becker, A.E., Neches, W.H., Devine, W.A., ...
Conotruncal repair for tetralogy of fallot: midterm results (1998)
Kurosawa, H., Morita, K., Yamagishi, M., Shimizu, S., Becker, A.E., Anderson, R.H.
Jackson, M., Connell, M.G., Smith, A., Drury, J., Anderson, R.H.
Objectives: To examine morphological similarities between "classically different" congenital heart lesion types induced in fetal rats by the cardiac teratogen...
Jackson, M., Connell, M.G., Smith, A., Anderson, R.H.
Objectives: To study the development of aortic to mitral fibrous continuity in the normal rat heart. Methods: The hearts and great vessels of normally developed rat embryos and fetuses aged between...
Marron, K, Wharton, J, Sheppard, M N, Gulbenkian, S, Royston, D, Yacoub, M H, ...
Objective: The endocardium contains an extensive neural plexus, the composition and function of which are unclear. The aim of this study was to characterise the innervation of the endocardium in...
Further observations on conduction tissues in univentricular hearts--surgical implications (1981)
ESSED, C. E., HO, S. YEN, SHINEBOURNE, E. A., JOSEPH, M. C., ANDERSON, R. H.
Two univentricular hearts are described with particular reference to the surgical anatomy of their conduction tissues. The first was of left ventricular type with right-sided outlet chamber. The...
Data Reconfiguration Service: An implementation specification (1971)
R.H. Anderson, V.G. Cerf, E. Harslem, J.F. Heafner, J. Madden, R.M. Metcalfe, ...
Current status: UNKNOWN
Status report on proposed Data Reconfiguration Service (1971)
R.H. Anderson, V.G. Cerf, E. Harslem, J.F. Heafner, J. Madden, R.M. Metcalfe, ...
Current status: UNKNOWN
Language-machine for data reconfiguration (1970)
R.H. Anderson, E. Harslem, J.F. Heafner
Current status: UNKNOWN
The innervation of the human myocardium at birth.
Chow, L T, Chow, S S, Anderson, R H, Gosling, J A
In order to delineate the type and distribution of autonomic nerves within the atrial and ventricular myocardium of the neonatal human heart, numerous samples of atrial and ventricular myocardium...
A quantitative study of nerve distribution in the conduction system of the guinea pig heart.
Crick, S J, Sheppard, M N, Anderson, R H, Polak, J M, Wharton, J
Quantitative measurements of relative nerve density were achieved using computer-assisted image analysis of immunohistochemically and histochemically defined nerves in the conduction system of the...
Anatomical closure of the ductus arteriosus: a study in 35 specimens.
The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of...
Restivo, A, Smith, A, Wilkinson, J L, Anderson, R H
The morphology of the medial papillary muscle complex of the right ventricle was studied in 81 normal hearts from subjects ranging in age from 20 weeks of gestation to 13 months. The position of the...
Sudden Death in Infancy: A Study of Cardiac Specialized Tissue
Anderson, R. H., Bouton, J., Burrow, C. T., Smith, Audrey
The hearts from 15 cot death patients have been compared with those of 15 controls. In one of the cot death patients an accessory atrioventricular connexion known to be capable of producing...
Cardiac conduction disorders in six infants with "near-miss" sudden infant deaths.
Keeton, B R, Southall, E, Rutter, N, Anderson, R H, Shinebourne, E A, Southall, D P
Cardiac conduction disorders caused sudden serious illnesses in six infants that might have been fatal if diagnosis and treatment had been delayed. These cases provide circumstantial evidence to...
Study of cardiac arrhythmias and other forms of conduction abnormality in newborn infants.
Southall, D P, Orrell, M J, Talbot, J F, Brinton, R J, Vulliamy, D G, Johnson, A M, ...
In an unselected population of 2030 newborn infants studied by electrocardiography (ECG) between April 1975 and April 1977, 35 were found to have arrhythmias or other cardiac conduction...
A new look at the neonatal electrocardiogram.
Southall, D P, Vulliamy, D G, Davies, M J, Anderson, R H, Shinebourne, E A, Johnson, A M
Among 818 newborn babies whose electrocardiograms (ECGs) were recorded between April 1975 and April 1976 were 57 babies with recordings that fell outside the accepted normal range. Preliminary...
The innervation of the human myocardium at birth.
Chow, L T, Chow, S S, Anderson, R H, Gosling, J A
In order to delineate the type and distribution of autonomic nerves within the atrial and ventricular myocardium of the neonatal human heart, numerous samples of atrial and ventricular myocardium...
A quantitative study of nerve distribution in the conduction system of the guinea pig heart.
Crick, S J, Sheppard, M N, Anderson, R H, Polak, J M, Wharton, J
Quantitative measurements of relative nerve density were achieved using computer-assisted image analysis of immunohistochemically and histochemically defined nerves in the conduction system of the...
Anatomical closure of the ductus arteriosus: a study in 35 specimens.
The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of...
Restivo, A, Smith, A, Wilkinson, J L, Anderson, R H
The morphology of the medial papillary muscle complex of the right ventricle was studied in 81 normal hearts from subjects ranging in age from 20 weeks of gestation to 13 months. The position of the...
Sudden Death in Infancy: A Study of Cardiac Specialized Tissue
Anderson, R. H., Bouton, J., Burrow, C. T., Smith, Audrey
The hearts from 15 cot death patients have been compared with those of 15 controls. In one of the cot death patients an accessory atrioventricular connexion known to be capable of producing...
Cardiac conduction disorders in six infants with "near-miss" sudden infant deaths.
Keeton, B R, Southall, E, Rutter, N, Anderson, R H, Shinebourne, E A, Southall, D P
Cardiac conduction disorders caused sudden serious illnesses in six infants that might have been fatal if diagnosis and treatment had been delayed. These cases provide circumstantial evidence to...
Study of cardiac arrhythmias and other forms of conduction abnormality in newborn infants.
Southall, D P, Orrell, M J, Talbot, J F, Brinton, R J, Vulliamy, D G, Johnson, A M, ...
In an unselected population of 2030 newborn infants studied by electrocardiography (ECG) between April 1975 and April 1977, 35 were found to have arrhythmias or other cardiac conduction...
A new look at the neonatal electrocardiogram.
Southall, D P, Vulliamy, D G, Davies, M J, Anderson, R H, Shinebourne, E A, Johnson, A M
Among 818 newborn babies whose electrocardiograms (ECGs) were recorded between April 1975 and April 1976 were 57 babies with recordings that fell outside the accepted normal range. Preliminary...
Atresia of left atrioventricular orifice
Wenink, Arnold C G, Thiene, G, Anderson, R H, Macartney, F J
Assessment of atrioventricular septal defects by two dimensional echocardiography.
Smallhorn, J F, Tommasini, G, Anderson, R H, Macartney, F J
Ninety-six patients with an atrioventricular septal defect were assessed by two dimensional echocardiography. Forty-eight patients were judged as having two discrete valve orifices. In this group, 37...
Ventricular septal defects. Two dimensional echocardiographic and morphological correlations.
Sutherland, G R, Godman, M J, Smallhorn, J F, Guiterras, P, Anderson, R H, Hunter, S
To evaluate the ability of two dimensional echocardiography to identify and classify ventricular septal defects, 280 infants and children with clinically significant ventricular septal defects were...
Recognition of imperforate atrioventricular valves by two dimensional echocardiography.
Rigby, M L, Gibson, D G, Joseph, M C, Lincoln, J C, Shinebourne, E A, Shore, D F, ...
The majority of hearts in which selective right or left atrial angiography shows no direct communication between one atrium and a ventricular chamber are considered to be examples of atresia of the...
Straddling atrioventricular valve with absent atrioventricular connection. Report of 10 cases.
Ho, S Y, Milo, S, Anderson, R H, Macartney, F J, Goodwin, A, Becker, A E, ...
Smallhorn, J F, Anderson, R H, Macartney, F J
The value of two dimensional echocardiography in identifying communications between the ascending aorta and pulmonary trunk or individual pulmonary arteries was assessed in 24 children, all of whom...
Smallhorn, J F, De Leval, M, Stark, J, Somerville, J, Taylor, J F, Anderson, R H, ...
Five patients with isolated clefts in the anterior leaflet of the mitral valve, unassociated with atrioventricular septal defects, are described. All had significant mitral regurgitation, with the...
Smallhorn, J F, Anderson, R H, Macartney, F J
Interrupted aortic arch is a rare condition, usually lethal in early infancy without treatment. The only characteristic feature on conventional non-invasive investigation is peripheral pulse...
Restivo, A, Ho, S Y, Anderson, R H, Cameron, H, Wilkinson, J L
Four cases of absent left atrioventricular connection are reported. The observations from these cases have been used to emphasise problems concerning the use of the confusing terms "tricuspid" and...
Suprasternal cross-sectional echocardiography in assessment of patient ducts arteriosus.
Smallhorn, J F, Huhta, J C, Anderson, R H, Macartney, F J
Ninety-four patients with patent ductus arteriosus, whose ages ranged from 28 weeks gestation to 8 years, were assessed by suprasternal cross-sectional echocardiography. A further group of 37 cases...
Smallhorn, J F, Sutherland, G R, Anderson, R H, Macartney, F J
Ninety two patients with both atrioventricular valves attached to the atrial septum, roofing a perimembranous inlet ventricular septal defect, were assessed by cross-sectional echocardiography. In...
Cross-sectional echocardiographic diagnosis of systemic venous return.
Huhta, J C, Smallhorn, J F, Macartney, F J, Anderson, R H, De Leval, M
To determine the sensitivity and specificity of cross-sectional echocardiography in diagnosing anomalous systemic venous return we used the technique in 800 consecutive children with congenital heart...
Faggian, G, Frescura, C, Thiene, G, Bortolotti, U, Mazzucco, A, Anderson, R H
Among 61 heart specimens of tetralogy of Fallot with or without pulmonary atresia, four presented with an accessory tricuspid valve leaflet. This structure caused partial or almost complete...
Smallhorn, J F, Anderson, R H, Macartney, F J
Cross-sectional echocardiograms of 18 neonates and infants with coarctation of the aorta and ventricular septal defect were retrospectively assessed. With a combination of subcostal and precordial...
Atrioventricular discordance. Cross-sectional echocardiographic--morphological correlative study.
Sutherland, G R, Smallhorn, J F, Anderson, R H, Rigby, M L, Hunter, S
Morphology of ventricular septal defect associated with coarctation of aorta.
Anderson, R H, Lenox, C C, Zuberbuhler, J R
It is now well established that the morphology of the ventricular septal defect associated with interrupted aortic arch is such as to compromise blood flow to the ascending aorta. Though there is...
Evaluation of fetal arrhythmias by echocardiography.
Allan, L D, Anderson, R H, Sullivan, I D, Campbell, S, Holt, D W, Tynan, M
The normal fetal heart shows variation in rate and rhythm. Twenty three cases that fell outside the normal patterns of variation of heart rate and rhythm were evaluated by echocardiography. Ten...
Cross-sectional echocardiographic assessment of coarctation in the sick neonate and infant.
Smallhorn, J F, Huhta, J C, Adams, P A, Anderson, R H, Wilkinson, J L, Macartney, F J
To establish an integrated non-invasive method for diagnosing coarctation, cross-sectional echocardiographic appearances of 48 neonates and infants with coarctation were combined with clinical...
Anatomical basis of cross sectional echocardiography.
Silverman, N H, Hunter, S, Anderson, R H, Ho, S Y, Sutherland, G R, Davies, M J
Ten hearts were cut in planes to simulate echocardiographic cuts which may be taken to visualise the anatomy of the cardiac chambers and great arteries. The various myocardial wall segments were...
Ursell, P C, Neill, C A, Anderson, R H, Ho, S Y, Becker, A E, Gerlis, L M
Endocardial fibroelastosis in neonates with hypoplasia of the left ventricle is usually associated with severe aortic stenosis or atresia. In this study three hearts were examined, in which severe...
The spectrum of atrioventricular discordance. A clinical study.
De Albuquerque, A T, Rigby, M L, Anderson, R H, Lincoln, C, Shinebourne, E A
The clinical, investigative, and surgical findings were reviewed in 47 patients with atrioventricular discordance who presented to the Brompton Hospital between January 1962 and June 1981. Although...
Disadvantageous closure of the interventricular communication in double outlet right ventricle.
Gerlis, L M, Dickinson, D F, Anderson, R H
A double outlet right ventricle was diagnosed in a 10 week old infant, in whom the ventricular septum was intact at the time of presentation. A large aneurysm of a membranous septal remnant was...
Macartney, F J, Rigby, M L, Anderson, R H, Stark, J, Silverman, N H
The precise method of surgical repair of double outlet right ventricle depends both on the relation of the interventricular communication to the cardiac outlets and on the course and insertion of the...
Robinson, P J, Sullivan, I D, Kumpeng, V, Anderson, R H, Macartney, F J
Cross sectional echocardiography can identify anomalous origin of the left coronary artery from the pulmonary trunk. It has been suggested that identification of the left coronary artery arising from...
Echocardiographic and anatomical correlations in fetal congenital heart disease.
Allan, L D, Crawford, D C, Anderson, R H, Tynan, M J
In a series of 1600 pregnancies 34 cases of congenital heart disease were correctly identified by fetal echocardiography. In each case echocardiographic diagnosis was confirmed by anatomical study....
Conduction system defects in three perinatal patients with arrhythmia.
Ho, S Y, Mortimer, G, Anderson, R H, Pomerance, A, Keeling, J W
The cardiac conduction systems of three patients who died in the perinatal period were studied histologically. Rhythm disturbances were observed in these patients immediately before death. The sinus...
Spectrum of congenital heart disease detected echocardiographically in prenatal life.
Allan, L D, Crawford, D C, Anderson, R H, Tynan, M
The spectrum of congenital heart disease seen in a series of 72 fetal anomalies detected echocardiographically differed from that seen in infancy. This reflects the selection of patients for referral...
Congenital heart malformations in the first year of life--a necropsy study.
Hegerty, A S, Anderson, R H, Ho, S Y
The hearts of 291 babies with congenital heart disease who died before the age of one were examined systematically by sequential segmental analysis to determine the lesions that were present. There...
Conducting tissues in congenitally corrected transposition with situs inversus.
Wilkinson, J L, Smith, A, Lincoln, C, Anderson, R H
Three cases of congenitally corrected transposition in situs inversus individuals were characterised by visceroatrial situs inversus, atrioventricular discordance, and ventiruloarterial discordance:...
Coarctation, tubular hypoplasia, and the ductus arteriosus. Histological study of 35 specimens.
A histological study has been made in an attempt to study further the relation between the ductus arteriosus, coarctation, and tubular hypoplasia of the aortic arch. Thirty-five aortic arch systems...
Developmental anatomy of the membranous part of the ventricular septum in the human heart.
The anatomy of the membranous part of the ventricular septum is described in 25 hearts from patients ranging in age from 15 weeks of gestation to the ninth decade of adult life. Both atrioventricular...
Morphological variations in pulmonary atresia with intact ventricular septum.
Zuberbuhler, J R, Anderson, R H
The morphological features of a series of 37 specimens of pulmonary atresia with intact ventricular septum were reviewed with particular emphasis on features which might influence the results of...
Nomenclature and classification of congenital heart disease.
Tynan, M J, Becker, A E, Macartney, F J, Jiménez, M Q, Shinebourne, E A, Anderson, R H
At present there is no universally accepted nomenclature for congenital cardiac malformations. Much of the controversy results from failure to distinguish the structural connections of the heart from...
Atresia of the right atrioventricular orifice with atrioventricular concordance.
Dickinson, D F, Wilkinson, J L, Smith, A, Anderson, R H
Three hearts are described in which a fibrous membrane was interposed between the right atrium and a formed but hypoplastic right ventricle, which possessed recognisable inlet, trabecular, and...
Two-chambered right ventricle: simulating two-chambered left ventricle.
Beitzke, A, Anderson, R H, Wilkinson, J L, Shinebourne, E A
Two cases are described of a most unusual variant of two-chambered right ventricle. In both the ventricular septal defect was between the distal chamber of the right ventricle and the left ventricle....
Dextrocardia--value of segmental analysis in its categorisation.
Calcaterra, G, Anderson, R H, Lau, K C, Shinebourne, E A
Dextrocardia can be defined as a heart in the right chest with the major axis to the right. This definition, however, conveys no information regarding the chamber arrangements and internal anatomy of...
Morphology and classification of atrioventricular defects.
Piccoli, G P, Gerlis, L M, Wilkinson, J L, Lozsadi, K, Macartney, F J, Anderson, R H
Anatomical studies were made on 114 necropsy specimens of atrioventricular defects with atrioventricular concordance. The malformation is characterised by disproportion between the ventricular inlet...
Morphology and classification of complete atrioventricular defects.
Piccoli, G P, Wilkinson, J L, Macartney, F J, Gerlis, L M, Anderson, R H
Anatomical studies were made on 70 necropsied hearts with atrioventricular defects from patients with situs solitus and atrioventricular concordance, all having a common atrioventricular orifice. The...
Macartney, F J, Rees, P G, Daly, K, Piccoli, G P, Taylor, J F, De Leval, M R, ...
Preoperative distinction between common atrioventricular orifice and ostium primum atrial septal defect may be difficult. To improve diagnostic accuracy, the right and left ventricle angiocardiograms...
Classification of ventricular septal defects.
Soto, B, Becker, A E, Moulaert, A J, Lie, J T, Anderson, R H
A classification with clinical significance is proposed for ventricular septal defect based on the study of 220 hearts with defects of the ventricular septum. All had atrioventricular and...
Echocardiographic and anatomical correlates in the fetus.
Allan, L D, Tynan, M J, Campbell, S, Wilkinson, J L, Anderson, R H
Fetal cardiac anatomy was studied in 200 pregnancies between 14 weeks' gestation and term using real time two-dimensional echocardiography. Eight scan planes were chosen as contributing valuable and...
Macartney, F J, Zuberbuhler, J R, Anderson, R H
The atrial morphology and venous connections were assessed "blind" in 51 necropsy specimens from patients with visceral heterotaxy. This was compared with bronchial morphology as established by...
De Tommasi, S, Daliento, L, Ho, S Y, Macartney, F J, Anderson, R H
We have analysed the atrioventricular junction, ventricular mass, and ventriculoarterial junction in 43 hearts with isomeric atrial chambers. Of the hearts, 32 had atrial chambers of bilateral right...
Left ventricular fibre architecture in man.
Greenbaum, R A, Ho, S Y, Gibson, D G, Becker, A E, Anderson, R H
In order to investigate the possibility of regional variation of ventricular structure, 25 normal postmortem human hearts were studied by inspection of cavity shape and subepicardial fibre...
Atresia of left atrioventricular orifice. Anatomical investigation in 62 cases.
Thiene, G, Daliento, L, Frescura, C, De Tommasi, M, Macartney, F J, Anderson, R H
Sixty-two hearts without a patent exit from the left atrium to the ventricular mass have been studied. All had situs solitus and laevocardia. The material consisted of 32 cases with coexistent aortic...
Identification of congenital cardiac malformations by echocardiography in midtrimester fetus.
Allan, L D, Tynan, M, Campbell, S, Anderson, R H
Fetal echocardiograms were performed in 21 pregnancies before midtrimester termination. All fetal heart specimens were collected and studied morphologically. Eighteen had been diagnosed as normal...
Rigby, M L, Anderson, R H, Gibson, D, Jones, O D, Joseph, M C, Shinebourne, E A
Most univentricular hearts have two chambers in their ventricular mass, only one of which possesses an atrioventricular connection. Categorisation into univentricular heart of right, left, or...
Assessment of total anomalous pulmonary venous connection by two-dimensional echocardiography.
Smallhorn, J F, Sutherland, G R, Tommasini, G, Hunter, S, Anderson, R H, Macartney, F J
Twenty-three patients with total anomalous pulmonary venous connection were studied by two-dimensional echocardiography. In all cases the diagnosis was made before invasive procedures, with surgical...
Conduction tissue changes associated with enlarged membranous septum--a cause of sudden death?
Smeeton, W M, Anderson, K R, Ho, S Y, Davies, M J, Anderson, R H
We have studied four hearts in which enlargement of the ventricular membranous septum was associated with histological abnormalities of the atrioventricular conduction tissues. Two of the cases...
Tricuspid atresia: analysis of coronary artery distribution and ventricular morphology.
Deanfield, J E, Tommasini, G, Anderson, R H, Macartney, F J
There is still disagreement concerning the precise nature of the anterior ventricular chamber in "tricuspid atresia". Some argue that it is a right ventricle, while our own previous studies have...
Double outlet right ventricle with 1-malposition of the aorta.
Lincoln, C, Anderson, R H, Shinebourne, E A, English, T A, Wilkinson, J L
Four patients are described with a recently recognized variant of double outlet right ventricle. Clinical examination favoured tetralogy of Fallot, but the chest X-ray suggested corrected...
'Posterior' transposition reconsidered.
Wilkinson, J L, Arnold, R, Anderson, R H, Acerete, F
Seven cases of transposition with an unusually posterior aorta and mitral-aortic fibrous continuity are described. The cases are similar to four cases published by Van Praagh et al. in 1971. The use...
Shinebourne, E A, Anderson, R H, Bowyer, J J
Striking variability has been observed in the presenting features in infancy of patients subsequently shown to have tetralogy of Fallot. Some patients presented with severe cyanosis in the neonatal...
Anatomically corrected malposition of great arteries.
Anderson, R H, Becker, A E, Losekoot, T G, Gerlis, L M
Four anomalous hearts are described in which the great arteries arise in unusual fashion from their morphologically appropriate ventricles. This malformation, previously termed anatomically corrected...
Cor triatriatum dexter with imperforate Ebstein's anomaly.
A case of cor triatriatum dexter is described in which the anomalous right atrial partition is identified as the right venous valve; there is an associated anomaly of the right atrioventricular valve...
Sequential chamber localization--logical approach to diagnosis in congenital heart disease.
Shinebourne, E A, Macartney, F J, Anderson, R H
A nomenclature is described for congenital heart disease employing sequential chamber localization. It is an eclectic system based in part upon the previous classifications of Van Praagh and Kirklin....
Morphogenesis of univentricular hearts.
Anderson, R H, Becker, A E, Wilkinson, J L, Gerlis, L M
Two main theories exist for the explanation of univentricular hearts. One states that the bulboventricular septum becomes realigned to form the interventricular septum, and that univentricular hearts...
Echocardiographic diagnosis of primitive ventricle with two atrioventricular valves.
Beardshaw, J A, Gibson, D G, Pearson, M C, Upton, M T, Anderson, R H
Anatomical studies have shown that the pathognomonic feature of primitive ventricle is absence of that portion of the interventricular septum which interposes between the atrioventricular valves. The...
Left juxtaposition of the auricles with l-position of the aorta. Report of 6 cases.
Allwork, S P, Urban, A E, Anderson, R H
Six hearts are described in which juxtaposition of the auricles to the left of the great arteries (left juxtaposition) was associated with l-postion of the aorta. Atrial anatomy was abnormal but...
Atresia of the right atrioventricular orifice.
Anderson, R H, Wilkinson, J L, Gerlis, L M, Smith, A, Becker, A E
The results are reported of a study of 83 necropsied hearts with atresia of the right atrioventricular orifice. It is emphasised that right atrial or atrioventricular orificial atresia is a better...
What should we call the 'crista'?
Anderson, R H, Becker, A E, Van Mierop, L H
Review of published work concerning congenital cardiac anomalies reveals that at least four different structures have been described as the crista supraventricular, in addition to the structure which...
Complete heart block as a consequence of atriondal discontinuity.
Gerlis, L M, Anderson, R H, Becker, A E
We have recently studied a case of complete heart block in which there was considerable difficulty in deciding whether it was of congenital or acquired origin. This was because the heart block was...
Architecture of atrial musculature in humans.
Wang, K., Ho, S. Y., Gibson, D. G., Anderson, R. H.
OBJECTIVE--To investigate the gross arrangement of the principal muscular bundles of the two atria, and to suggest how it may contribute to contraction and spread of atrial excitation. DESIGN--A...
Vogel, M., Ho, S. Y., Anderson, R. H.
OBJECTIVE--To compare the reconstructions obtained by three dimensional echocardiography with the anatomical specimens used to generate the echocardiograms. DESIGN--The heart specimens were immersed...
The earliest site of atrial activation in patients with isomeric appendages.
Uemura, H., Yagihara, T., Kawashima, Y., Okada, K., Anderson, R. H.
BACKGROUND--The sinus node is known to be duplicated in hearts with bilateral right appendages, but its site is uncertain when both appendages are of morphologically left pattern. OBJECTIVE--To...
Morphology of the sinus node in human and mouse hearts with isomerism of the atrial appendages.
Ho, S. Y., Seo, J. W., Brown, N. A., Cook, A. C., Fagg, N. L., Anderson, R. H.
BACKGROUND--The location of the sinus node is known to be at best abnormal, or at worst unknown, in patients with isomerism of the morphologically left atrial appendage. In contrast, the sinus node...
Ventricular myoarchitecture in tetralogy of Fallot.
Sanchez-Quintana, D., Anderson, R. H., Ho, S. Y.
BACKGROUND: Little attention has been paid to the architecture of the muscle fibres of the ventricular walls in congenitally malformed hearts. In this study the gross pattern of myocardial fibres in...
Anatomical criteria for the diagnosis of sinus venosus defects.
Al Zaghal, A. M., Li, J., Anderson, R. H., Lincoln, C., Shore, D., Rigby, M. L.
BACKGROUND: The diagnosis of sinus venosus defects remains a matter of debate. It is crucial to provide solid anatomical criteria, by identifying the very nature of the atrial septum relative to...
Disposition of the sinus node in left-sided juxtaposition of the atrial appendages.
Ho, S Y, Monro, J L, Anderson, R H
In view of the complex cardiac anomalies frequently associated with left-sided juxtaposition of the atrial appendages the disposition of the sinus node has been studied in 6 of these hearts. While...
Location and vascular supply of sinus node in human heart.
Anderson, K R, Ho, S Y, Anderson, R H
The exact location of the sinus node was determined in 25 infant hearts using reconstructive techniques. The sinus node was found to lie on the lateral aspect of the superior cavo-atrial junction in...
Morphogenesis of bulboventricular malformations. II. Observations on malformed hearts.
Anderson, R H, Wilkinson, J L, Arnold, R, Becker, A E, Lubkiewicz, K
Anderson, C, Devine, W A, Anderson, R H, Debich, D E, Zuberbuhler, J R
A series of 1042 reports of necropsies on children dying at Children's Hospital of Pittsburgh was reviewed. In each case, note was taken of the status of the spleen, the lobation of the lungs, the...
Morphological evaluation of atrioventricular septal defects by magnetic resonance imaging.
Parsons, J M, Baker, E J, Anderson, R H, Ladusans, E J, Hayes, A, Qureshi, S A, ...
Twelve patients aged between 2 weeks and 22 months (median 6 weeks) with atrioventricular septal defects were examined with a 1.5 T, whole body, magnetic resonance imaging system. Ten patients had a...
Stümper, O, Fraser, A G, Ho, S Y, Anderson, R H, Chow, L, Davies, M J, ...
Transoesophageal echocardiographic imaging in the longitudinal axis is a recent addition to the non-invasive evaluation of congenital and acquired heart disease. The technique provides unique images...
Sharland, G K, Chita, S K, Fagg, N L, Anderson, R H, Tynan, M, Cook, A C, ...
OBJECTIVE--To examine the relation between a characteristic form of left ventricular dysfunction in the fetus and abnormalities of the aortic valve and endocardial fibroelastosis of the left...
Ferreira, S M, Ho, S Y, Anderson, R H
OBJECTIVE--To determine the anatomical variability of the oval fossa in cases of atrial septal defect and to find out which factors might make such defects suitable or unsuitable for closure by...
Gerlis, L M, Schmidt-Ott, S C, Ho, S Y, Anderson, R H
OBJECTIVE--Since 1905 there have been many reports of cases in which the right ventricle was deficient in myocardium. Several terms have been used to describe this condition. Of these, "Uhl's...
Innervation of the human cardiac conduction system at birth.
Chow, L T, Chow, S S, Anderson, R H, Gosling, J A
OBJECTIVE--To study the pattern of innervation of the conduction system of the neonatal heart in humans. DESIGN--A prospective analysis based on immunohistochemical and enzyme histochemical...
The cross sectional anatomy of ventricular septal defects: a reappraisal.
Baker, E J, Leung, M P, Anderson, R H, Fischer, D R, Zuberbuhler, J R
The cross sectional echocardiographic description of holes in the ventricular septum has been unsatisfactory, chiefly because there are so many classifications of this defect. The accurate...
Atrioventricular septal defect in prenatal life.
Machado, M V, Crawford, D C, Anderson, R H, Allan, L D
In a series of more than 3500 pregnancies referred for fetal echocardiography, 29 cases of atrioventricular septal defect were detected in the fetus. There was a chromosomal anomaly in 14 of these...
Coarctation of the aorta in prenatal life: an echocardiographic, anatomical, and functional study.
Allan, L D, Chita, S K, Anderson, R H, Fagg, N, Crawford, D C, Tynan, M J
In a prospective echocardiographic study of over 2000 pregnancies, 24 fetuses were found to have dilatation of the right ventricle and pulmonary artery when these structures were compared with those...
Darvell, F J, Rossi, I R, Rossi, M B, Fayers, P, Anderson, R H, Rigby, M L, ...
Overall survival after Mustard's operation was assessed in 130 patients with complete transposition of the great arteries and an intact ventricular septum who were operated on at the Brompton...
Griffin, M L, Sullivan, I D, Anderson, R H, Macartney, F J
To gain a better understanding of the anatomy of doubly committed subarterial defects and its relation to findings at cross sectional echocardiography and angiocardiography, eight necropsy specimens...
Angelini, A, Allan, L D, Anderson, R H, Crawford, D C, Chita, S K, Ho, S Y
Thirty normal hearts from fetuses aborted at 10-33 weeks' gestation were measured directly and the results were compared with echocardiographic measurements in 20 normal live fetuses of 23-27 weeks'...
Sharma, S, Devine, W, Anderson, R H, Zuberbuhler, J R
The morphology of the atrial appendages was examined in 1842 specimen hearts from patients with congenital lesions. The external and internal features that permitted the identification of the right...
Wharton, J, Anderson, R H, Springall, D, Power, R F, Rose, M, Smith, A, ...
Atrial natriuretic peptide immunoreactivity was found in ventricular and atrial tissues with specific antisera raised to the amino and carboxy terminal regions of the precursor molecule. In 13...
Carvalho, J S, Rigby, M L, Shinebourne, E A, Anderson, R H
The cross sectional echocardiograms of 150 children with atrioventricular septal defects were reviewed to determine the spatial orientation of the ventricles. In 125 cases with usual atrial...
Magnetic resonance imaging of coarctation of the aorta in infants: use of a high field strength.
Baker, E J, Ayton, V, Smith, M A, Parsons, J M, Maisey, M N, Ladusans, E J, ...
Nineteen infants with suspected coarctation of the aorta were studied with electrocardiographically gated magnetic resonance imaging on a 1.5 T whole body imaging system. In all cases imaging was...
Diagnostic echocardiographic features of the sinus venosus defect.
Ettedgui, J A, Siewers, R D, Anderson, R H, Park, S C, Pahl, E, Zuberbuhler, J R
To establish the diagnostic criteria for a sinus venosus atrial septal defect cross sectional echocardiograms, cineangiograms, and surgical notes of all patients with this diagnosis seen at the...
Fong, L V, Anderson, R H, Siewers, R D, Trento, A, Park, S C
Six patients with anomalous origin of one pulmonary artery from the ascending aorta were reviewed. Four had anomalous origin of the right pulmonary artery and two had anomalous origin of the left...
Angelini, A, Ho, S Y, Anderson, R H, Davies, M J, Becker, A E
The mitral annulus is the point at which the atrial and ventricular walls meet the base of the mitral valve cusps. The suggestion that a variant of this arrangement termed "disjunction" was...
Leung, M, Rigby, M L, Anderson, R H, Wyse, R K, Macartney, F J
Ebstein's anomaly of the tricuspid valve is characterised by downstream displacement of the tricuspid leaflets. In the case of the septal leaflet, the result is exaggerated offsetting of the...
A rare variant of common arterial trunk.
Rubay, J E, Macartney, F J, Anderson, R H
A 13 day old baby was admitted to hospital with multiple abnormalities, increasing cyanosis, and cardiac failure. Cardiac catheterisation was performed on the day of admission and he died shortly...
Absent right superior caval vein (vena cava) with normal atrial arrangement.
Choi, J Y, Anderson, R H, Macartney, F J
Eight cases of absent right superior caval vein (vena cava) with normal atrial arrangement from the Great Ormond Street database were reviewed. In each case the right subclavian vein and jugular vein...
Conjoined twins, right atrial isomerism, and sequential segmental analysis.
Rossi, M B, Burn, J, Ho, S Y, Thiene, G, Devine, W A, Anderson, R H
Three cases of twins conjoined across the chest were examined. In one set, one twin showed right atrial isomerism and the other showed the usual atrial arrangement. The other two sets showed the...
Magnetic resonance imaging at a high field strength of ventricular septal defects in infants.
Baker, E J, Ayton, V, Smith, M A, Parsons, J M, Ladusans, E J, Anderson, R H, ...
Magnetic resonance imaging at a high field strength has potential benefits for the study of the heart in infants, which is when most congenital heart disease presents. Seventeen infants with various...
The terminal crest: morphological features relevant to electrophysiology
Sánchez-Quintana, D, Anderson, R H, Cabrera, J A, Climent, V, Martin, R, Farré, J, ...
Objective: To investigate the detailed anatomy of the terminal crest (crista terminalis) and its junctional regions with the pectinate muscles and intercaval area to provide the yardstick for...
The forces generated within the musculature of the left ventricular wall
Lunkenheimer, P P, Redmann, K, Florek, J, Fassnacht, U, Cryer, C W, Wübbeling, F, ...
Objectives: To test the hypothesis that two populations of myocardial fibres—fibres aligned parallel to the surfaces of the wall and an additional population of fibres that extend obliquely through...
Sinus node revisited in the era of electroanatomical mapping and catheter ablation
Sánchez-Quintana, D, Cabrera, J A, Farré, J, Climent, V, Anderson, R H, Ho, S Y
Objective: To study the architecture of the human sinus node to facilitate understanding of mapping and ablative procedures in its vicinity.
The surgical anatomy of the conduction tissues.
Anderson, R H, Ho, S Y, Becker, A E
On the basis of our collective experience we have reviewed the disposition of the cardiac conduction tissues as they might be observed by the surgeon in both normal and abnormal hearts. The sinus...
Aneurysm of the coronary sinus.
Ho, S Y, Gupta, I, Anderson, R H, Lendon, M, Kerr, I
Two patients, an adult and a baby, with an aneurysm of the coronary sinus are described. This unusual anomaly was detected in the baby during angiographic investigations for congenital heart disease....
Parachute deformity of the tricuspid valve.
Milo, S, Stark, J, Macartney, F J, Anderson, R H
A parachute deformity of the tricuspid valve occurred in a heart with atrioventricular concordance, double outlet right ventricle, and straddling mitral valve. Although to the best of our knowledge...
Essed, C E, Ho, S Y, Hunter, S, Anderson, R H
The conduction tissue in a univentricular heart of the right ventricular type with a right-sided rudimentary chamber was studied. Both an anterior and conventional node were found, the anterior node...
Hypoplastic left heart syndrome: can this malformation be treated surgically?
Milo, S, Ho, S Y, Anderson, R H
A corrective technique for the surgical treatment of hypoplastic left heart syndrome is proposed. This technique is compatible with subsequent growth because it uses the patient's own tissues...
Southall, D P, Arrowsmith, W A, Oakley, J R, McEnery, G, Anderson, R H, Shinebourne, E A
Two neonates with arrhythmias and the long QT syndrome are described. The arrhythmias were detected in utero and both infants were apparently well after birth. The first infant, although well, had a...