R. L. McIsaac

Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist.

McIsaac, R L, Johnston, B J, Fielding, L P

The effect of impromidine, a new histamine-H2-receptor agonist, on gastric mucosal blood flow (neutral red clearance) and acid secretion was studied in nine volunteers. Impromidine stimulated a...

Acute treatment of duodenal ulcer: a multicentre study to compare ranitidine 150 mg twice daily with ranitidine 300 mg once at night.

Lee, F I, Reed, P I, Crowe, J P, McIsaac, R L, Wood, J R

A randomised double blind clinical trial was undertaken in the UK and Ireland to compare ranitidine 300 mg given as a single bed time tablet with ranitidine 150 mg twice daily in the acute treatment...

Proceedings: The effect of atropine on pentagastrin-induced gastric acid secretion and mucosal blood flow in the conscious rat.

McIsaac, R L, Wilson, G M

Studies on the mechanism of action by which 5H-[1]-benzopyrano-[2,3,-b]-pyridin-5-ol (AH 6696) inhibits gastric acid secretion [proceedings].

Ashby, P, Curwain, B P, Daly, M J, McIsaac, R L

Can the actions of adrenoceptor agonists and antagonists on pentagastrin-induced gastric secretion be due to their effects on histamine formation?

Curwain, B.P., Holton, Pamela, McIsaac, R.L., Spencer, Jan

1 The effects of some adrenoceptor agonists and antagonists which have been reported to affect histamine formation in leucocytes (Assem & Feigenbaum, 1972) have been investigated on gastric secretion...

Sensitivity of the parietal cell and gastric microvasculature to histamine and histamine antagonists in the dog [proceedings]

Knight, S. E., McIsaac, R. L., Rennie, C. D.