Scientific Commons: R. M.

Evaluation of Moringa oleifera Leaf Extract on Alcohol-induced Hepatotoxicity (2006)

Nadro,
M.S.,
Arungbemi,
R.M.,
Dahiru,
D.

A study on the protective effect of Moringa oleifera leaf extract in acute alcohol-induced hepatotoxicity in rats was evaluated. Rats fed alcohol only produced significant increase in the levels of...

Single-Crystal X-Ray and Neutron Powder Diffraction Investigation of the Phase Transition in Tetrachlorobenzene. (2006)

Barnett,
S.A.,
Broder,
C.K.,
Shankland,
K.,
...

Simplification and its consequences in biological modelling: Conclusions from a study of calcium oscillations in hepatocytes (2006)

Hetherington,
J.P.J.,
Warner,
A.,
Seymour,
R.M.

The control of saccade trajectories: direction of curvature depends upon prior knowledge of target location and saccade latency. (2006)

Walker,
R.M.,
McSorley,
E.,
Haggard,
P.

Targeting C-reactive protein for treatment of cardiovascular disease (2006)

Pepys,
M.B.,
Hirschfield,
G.M.,
Tennent,
G.A.,
...

X-ray absorption spectroscopy and high-energy XRD study of the local environment of copper in antibacterial copper-releasing degradable phosphate glasses (2006)

Pickup,
D.M.,
Ahmed,
I.,
FitzGerald,
V.,
...

Recognizing the Albian-Cenomanian (OAE1d) sequence boundary using plant carbon isotopes: Dakota Formation, Western Interior Basin, USA, (2006)

Gröcke,
D.R.,
Ludvigson,
G.A.,
Witzke,
B.L.,
...

Long-term outcome of high-dose melphalan and autologous stem cell transplantation for AL amyloidosis (2006)

Perz,
J.B.,
Rahemtulla,
A.,
Giles,
C.,
...

ESS gene expression of X-linked imprinted genes subject to sexual selection (2006)

Seymour,
R.M,
Pomiankowski,
A.

We define ESS (Evolutionary Stable Strategy) conditions for the evolution of genomic imprinting at an X-linked locus. The system analysed is designed for mammalian imprinting in which X-linked genes...

Introducing Dental Implants (2006)

Hobkirk,
J.A.,
Watson,
R.M.,
Searson,
L.J.J.

Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: A London Lung Cancer Group multicenter randomized clinical trial and meta-analysis (2006)

Spiro,
S.G.,
James,
L.E.,
Rudd,
R.M.,
...

Maculopathy due to the R345W substitution in fibulin-3: distinct clinical features, disease variability, and extent of retinal dysfunction. (2006)

Michaelides,
M.,
Jenkins,
S.A.,
Brantley,
M.A.Jr.,
...

Jornalismo, publicidade e anunciantes: alguns constrangimentos do dia a dia dos jornalistas (2005)

SOUZA,
R.M

Trabalho apresentado no II Colóquio Brasil-Estados Unidos de Ciências da Comunicação, evento componente do XXVIII Congresso Brasileiro de Ciências da...

A sedução do colunismo: uma análise das colunas de Ancelmo Gois e Ricardo Boechat. (2005)

SOUZA,
R.M

Trabalho apresentado na Sessão de Temas Livres durante o XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005. Resumo: O...

Probing the vortex state of PrRu₄Sb₁₂ through muon spin rotation and relaxation (2005)

Adroja,
D.T.,
Hillier,
A.D.,
Park,
J.G.,
...

Adult health and social outcomes of children who have been in public care: population-based study. (2005)

Viner,
R.M.,
Taylor,
B.

Effect of HIV infection and antiretroviral therapy on hepatitis B virus specific T-cell responses in patients who have resolved HBV infection. (2005)

Lascar,
R.M.,
Lopes,
A.R.,
Gilson,
R.J.C.,
...

Television viewing in early childhood predicts adult body mass index (2005)

Viner,
R.M.,
Cole,
T.J.

OBJECTIVES: To examine the effects of duration, timing and type of television (TV) viewing at age 5 years on body mass index (BMI) in adult life. STUDY DESIGN AND METHODS: 1970 British Birth Cohort,...

The role of ABO histo-blood group antigens in viral infections (2005)

Gustafsson,
K.,
Durrbach,
A.,
Seymour,
R.M.,
...

Glycans have the potential to carry more variation than either proteins or nucleic acids. Terminal glycan variation exists both between as well as within species as distant as bacteria and humans....

Measuring site specific cluster surface interaction (2005)

Hoffmann,
R.,
Barth,
C.,
Foster,
A.S.,
...

Adult socioeconomic, educational, social, and psychological outcomes of childhood obesity: a national birth cohort study (2005)

Viner,
R.M.,
Cole,
T.J.

OBJECTIVES: To assess adult socioeconomic, educational, social, and psychological outcomes of childhood obesity by using nationally representative data. DESIGN: 1970 British birth cohort....

Young people's health: the need for action (2005)

Viner,
R.M.,
Barker,
M.

Engaging adolescents with their health can prevent a lifetime of bad habits and should be a priority for an efficient future health service.

Liver transplantation in children: part 1 - peri-operative issues (2005)

Taylor,
R.M.,
Franck,
L.S.,
Gibson,
F.,
...

This two-part review provides a comprehensive summary of clinical and research literature on paediatric liver transplantation. Part 1 outlines the peri-operative issues of liver transplantation,...

Liver transplantation in children: part 2 - long-term issues (2005)

Taylor,
R.M.,
Franck,
L.S.,
Gibson,
F.,
...

This two-part review provides a comprehensive summary of clinical and research literature on paediatric liver transplantation. Part 2 focuses on the long-term physical consequences and psychological...

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells (2005)

Reynolds,
N.,
Collier,
B.,
Maratou,
K.,
...

Gametogenesis is a complex process subject to strict controls at both levels of transcription and translation. Members of a family of conserved RNA-binding proteins encoded by the DAZ genes are...

Echocardiographic features of the morphologically right ventriculo-arterial junction (2005)

Martinez,
R.M.,
Anderson,
R.H.

Macrophage inflammatory protein-1 alpha as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions (2005)

Miyazaki,
D.,
Nakamura,
T.,
Toda,
M.,
...

Regulation of the immune response requires the cooperation of multiple signals in the activation of effector cells. For example, T cells require signals emanating from both the TCR for antigen (upon...

Survey on haematopoietic stem cell transplantation for children in Europe (2005)

Miano,
M.,
Cancedda,
R.,
Hartmann,
O.,
...

A recent report, prepared in March 2003, regarding the paediatric transplantation activity registered between 1970 and 2002 in the European Bone Marrow Transplantation (EBMT) database showed a...

Allogeneic stem cell transplantation in X-linked lymphoproliferative disease: two cases in one family and review of the literature (2005)

Lankester,
A.C.,
Visser,
L.F.,
Hartwig,
N.G.,
...

Summary:X-linked lymphoproliferative disease (XLP) is a rare immunodeficiency caused by mutations in the signaling lymphocyte activating molecule-associated protein/SH2D1A gene and characterized by a...

Clinical and genetic spectrum of pyruvate dehydrogenase deficiency: Dihydrolipoamide acetyltransferase (E2) deficiency (2005)

HEad,
R.A.,
Brown,
R.M.,
Zolkipli,
Z,
...

Pyruvate dehydrogenase deficiency is a major cause of primary lactic acidosis and neurological dysfunction in infancy and early childhood. Most cases are caused by mutations in the X-linked gene for...

Health care providers' orientations towards common low back pain predict perceived harmfulness of physical activities and recommendations regarding return to normal activity (2005)

Houben,
R.M.,
Ostelo,
R.W.,
Vlaeyen,
J.W.,
...

The Pain Attitudes and Beliefs Scale for Physiotherapists (PABS-PT) differentiates between a biomedical versus a biopsychosocial treatment orientation with regard to common low back pain. This study...

Hyperinsulinaemic hypoglycaemia in Beckwith-Wiedemann syndrome (BWS) due to defects in the function of pancreatic {beta}-cell ATP-sensitive K+ channels (2005)

Hussain,
K.,
Cosgrove,
K.E.,
Shepherd,
R.M.,
...

Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth syndrome which is clinically and genetically heterogeneous. Hyperinsulinaemic hypoglycemia occurs in about 50% of children with BWS and in...

Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels (2005)

Hussain,
K.,
Cosgrove,
K.E.,
Shepherd,
R.M.,
...

Background: Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth syndrome that is clinically and genetically heterogeneous. Hyperinsulinemic hypoglycemia occurs in about 50% of children with...

Hearts with isomerism of the right atrial appendages - one of the worst forms of disease in 2005 (2005)

Freedom,
R.M.,
Jaeggi,
E.T.,
Lim,
J.S.,
...

The morphological spectrum of ventricular noncompaction (2005)

Freedom,
R.M.,
Yoo,
S.J.,
Perrin,
D.,
...

The significance of ventriculo-arterial connections in the setting of pulmonary atresia with an intact ventricular septum (2005)

Freedom,
R.M.,
Anderson,
.R.H.,
Perrin,
D.

EspJ is a prophage-carried type III effector protein of attaching and effacing pathogens that modulates infection dynamics (2005)

Dahan,
S.,
Wiles,
S.,
La Ragione,
R.M.,
...

Enterohemorrhagic Escherichia coli, enteropathogenic E. coli, and Citrobacter rodentium are highly adapted enteropathogens that successfully colonize their host's gastrointestinal tract via the...

Exon array CGH: Detection of copy-number changes at the resolution of individual exons in the human genome (2005)

Dhami,
P.,
Coffey,
A.J.,
Abbs,
S.,
...

The development of high-throughput screening methods such as array-based comparative genome hybridization (array CGH) allows screening of the human genome for copy-number changes. Current array CGH...

Kohlschutter syndrome in siblings (2005)

Donnai,
D.,
Tomlin,
P.I.,
Winter,
R.M.

Kohlschutter syndrome is a rare neurodegenerative disorder presenting with intractable seizures, developmental regression and characteristic hypoplastic dental enamel indicative of amelogenesis...

Normal and abnormal structure of the ventriculo-arterial junctions (2005)

Anderson,
.R.H.,
Freedom,
R.M.

Disruption of Smooth Pursuit Eye Movements in cirrhosis: relationship to hepatic encephalopathy and its treatment (2005)

Montagnese,
S.,
Jackson,
C.,
Gordon,
H.M.,
...

Introducing Dental Implants (2005)

Hobkirk,
J.A.,
Watson,
R.M.,
Searson,
L.J.J.

TNF-à neutralization in cytokine-driven diseases: a mathematical model to account for therapeutic success in rheumatoid arthritis but therapeutic failure in systemic inflammatory response syndrome (2005)

Jit,
M.,
Henderson,
B.,
Stevens,
M.,
...

Effect of HIV and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection. (2005)

Lascar,
R.M.,
Lopes,
A.R.,
Gilson,
R.J.,
...

Macrophage inflammatory protein-1alpha as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions (2005)

Miyazaki,
D.,
Nakamura,
T.,
Toda,
M.,
...

Regulation of the immune response requires the cooperation of multiple signals in the activation of effector cells. For example, T cells require signals emanating from both the TCR for antigen (upon...

The sarcoglycan-sarcospan complex localization in mouse retina is independent from dystrophins (2005)

Fort,
P.,
Estrada,
F.J.,
Bordais,
A.,
...

The sarcoglycan-sarcospan (SG-SSPN) complex is part of the dystrophin-glycoprotein complex that has been extensively characterized in muscle. To establish the framework for functional studies of...

TNF-857T, a genetic risk marker for acute anterior uveitis (2005)

Kuo,
N.W.,
Lympany,
P.A.,
Menezo,
V.,
...

PURPOSE: To determine the association between 17 single nucleotide polymorphisms (SNPs) of tumor necrosis factor-alpha, lymphotoxin-alpha, and the TNF-receptors genes (TNF, LTA, and TNFRSF1A and -B)...

Single-nucleotide polymorphisms in the SPARC gene are not associated with susceptibility to scleroderma. (2005)

Lagan,
A.L.,
Pantelidis,
P.,
Renzoni,
E.A.,
...

Recognizing the Albian-Cenomanian (OAE1d) sequence boundary using plant carbon isotopes: Dakota Formation, Western Interior Basin, USA. (2005)

Grcke,
D.R.,
Ludvigson,
G.A.,
Witzke,
B.L.,
...

The Maastrichtian record from Shatsky Rise (northwest Pacific): A tropical perspective on global ecological and oceanographic changes. (2005)

Frank,
T.D.,
Thomas,
D.J.,
Leckie,
R.M.,
...

Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/β-catenin pathway (2005)

Cavodeassi,
F.,
Carreira-Barbosa,
F.,
Young,
R.M.,
...

Commensal diversity and the immune system: Modelling the host-as-network (2005)

Seymour,
R.M.

Costly but worthless gifts facilitate courtship (2005)

Sozou,
P.D.,
Seymour,
R.M.

What are the characteristics of a good courtship gift? We address this question by modelling courtship as a sequential game. This is structured as follows: the male offers a gift to a female; after...

A prospective randomized multicenter gene expression study of docetaxel vs doxorubicin/cyclophosphamide preoperative trial in primary breast cancers (2005)

Makris,
A.,
Hisenback,
S.G.,
Yee,
D.,
...

Gene expression profiles as predictors of response to neoadjuvant taxotere and adriamycin/cyroxan:a propsective randomized trial in breas cancers (2005)

Chang,
J.C.,
Hisenback,
S.G.,
Yee,
D.,
...

The Maastrichtian record from Shatsky Rise (northwest Pacific): a tropical perspective on global ecological and oceanographic changes. (2005)

Frank,
T.D.,
Thomas,
D.J.,
Leckie,
R.M.,
...

3D analysis of facial morphology (2004)

Hammond,
P.,
Hutton,
T.J.,
Allanson,
J.E.,
...

Dense surface models can be used to analyze 3D facial morphology by establishing a correspondence of thousands of points across each 3D face image. The models provide dramatic visualizations of 3D...

C-terminal SRC kinase controls acute inflammation and granulocyte adhesion (2004)

Thomas,
R.M.,
Schmedt,
C.,
Novelli,
M.,
...

Plant-based production of biopharmaceuticals (2004)

Fischer,
R.,
Stoger,
E.,
Schillberg,
S.,
...

Plants are now gaining widespread acceptance as a general platform for the large-scale production of recombinant proteins. The first plant-derived recombinant pharmaceutical proteins are reaching the...

Evolution of the human ABO polymorphism through two complementary selective processes (2004)

Seymour,
R.M.,
Allan,
M.J.,
Pomiankowski,
A.,
...

The best-known example of terminal-glycan variation is the ABO histo-blood group polymorphism in humans. We model two selective forces acting on histo-blood group antigens that may account for this...

To age or not to age (2004)

Sozou,
P.D.,
Seymour,
R.M.

According to the antagonistic pleiotropy theory of ageing, natural selection has favoured genes conferring short-term benefits to the organism at the cost of deterioration in later life. The...

The prevalence and correlates of self-reported psychotic symptoms in the British population (2004)

Johns,
L.C.,
Cannon,
M.,
Singleton,
N.,
...

Background: The psychosis phenotype is generally thought of as a categorical entity However, there is increasing evidence that psychosis exists in the population as a continuum of severity rather...

Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. (2003)

Millatt,
L.J.,
Whitley,
G.S.,
Li,
D.,
...

The appearance of the feet in Pfeiffer syndrome caused by FGFR1 P252R mutation (2003)

Rossi,
M.,
Jones,
R.L.,
Norbury,
G.,
...

Septo-optic dysplasia, subglottic stenosis and skeletal abnormalities: a case report (2003)

Wakeling,
E.L.,
Dattani,
M.T.,
Bloch-Zupan,
A.,
...

We report a girl with septo-optic dysplasia in association with subglottic stenosis, sagittal craniosynostosis, osteoporosis and dental anomalies. It is uncommon for patients with septo-optic...

Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection (2003)

Lopes,
A.R.,
Jaye,
A.,
Dorrell,
L.,
...

Virus-specific CD8(+) T cells are known to play an important role in the control of HIV infection. In this study we investigated whether there may be qualitative differences in the CD8(+) T cell...

Introducing Dental Implants (2003)

Hobkirk,
J.A.,
Watson,
R.M.,
Searson,
L.J.J.

Microbial modulation of cytokine networks (2003)

Henderson,
B.,
Seymour,
R.M.

Reconstitution of hepatitis B virus (HBV)-specific T cell responses with treatment of human immunodeficiency virus/HBV coinfection (2003)

Lascar,
R.M.,
Gilson,
R.J.,
Lopes,
A.R.,
...

Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus (HBV)-coinfected patients receiving highly active antiretroviral therapy (HAART). In...

The cardioprotective and mitochondrial depolarising properties of exogenous nitric oxide in mouse heart (2003)

Bell,
R.M.,
Maddock,
H.L.,
Yellon,
D.M.

Molecular farming in plants: host systems and expression technology (2003)

Twyman,
R. M.,
Stoger,
E.,
Schillberg,
S.,
...

Plants provide an inexpensive and convenient system for the large-scale production of valuable recombinant proteins. This principle has been demonstrated by the commercial success of several...

ROR2 is mutated in hereditary brachydactyly with nail dysplasia, but not in Sorsby syndrome (2003)

Bacchelli,
C.,
Wilson,
L.C.,
Cook,
J.A.,
...

Balmer absorption variability and the disc wind of V592 Cas (2003)

Witherick,
D.K.,
Prinja,
R.K.,
Howell,
S.B.,
...

Variations in pleural fluid WBC count and differential counts with different sample containers and different methods (2003)

Conner,
B.D.,
Lee,
Y.C.G.,
Branca,
P.,
...

Ultrasound-guided thoracentesis: Is it a safer method? (2003)

Jones,
P.W.,
Moyers,
J.P.,
Rogers,
J.T.,
...

Optical Tomography of a Realistic Head-Shaped Phantom (2002)

Gibson,
A.,
Yusof,
R.M.,
Dehghani,
H.,
...

Random Walk Processes in ACT-R Mechanisms Lead to a Wild Distribution of Learning Times (2002)

Young,
R.M.,
Cox,
A.L.,
Greaves,
M.

Effects of sodium hypochlorite solution on root dentine composition (2002)

Driscoll,
C.O.,
Dowker,
S.E.P.,
Anderson,
P.,
...

Practical considerations for pharmaceutical antibody production in different crop systems (2002)

Stoger,
E.,
Sack,
M.,
Perrin,
Y.,
...

The potential of plant cells to produce functional recombinant antibodies has been demonstrated in a number of different plant systems. We present a comparative study of a well-defined target...

Principal component analysis of spectra with application to acoustic emissions from mechanical equipment (2002)

Tan,
C.C.,
Thornhill,
N.F.,
Belchamber,
R.M.

Expression and mutation analysis of BRUNOL3, a candidate gene for heart and thymus developmental defects associated with partial monosomy 10p (2002)

Lichtner,
P.,
Attie-Bitach,
T.,
Schuffenhauer,
S.,
...

Pseudodominant inheritance of Langer mesomelic dysplasia caused by a SHOX homeobox missense mutation (2002)

Shears,
D.J.,
Guillen-Navarro,
E.,
Sempere-Miralles,
M.,
...

We report the clinical and molecular analysis in a consanguineous family in which the skeletal dysplasias Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD) both segregate. A...

Is the water still hot? Sustainability and the thermal springs at Bath, England. (2002)

ATKINSON,
T.C.,
DAVISON,
R.M.

Prevalence and clinical course of pleural effusions after coronary artery bypass and cardiac surgery (2002)

Light,
R.W.,
Rogers,
J.T.,
Moyers,
J.P.,
...

Expression of MUL, a gene encoding a novel RBCC family ring-finger protein, in human and mouse embryogenesis (2001)

Lehesjoki,
A.,
Reed,
V.A.,
Gardiner,
R.M.,
...

We studied the expression of MUL, a gene encoding a novel member of the RING-B-Box-Coiled Coil family of zinc finger proteins that underlies the human inherited disorder, Mulibrey nanism. In early...

Cognitive Dimensions of Notations: Design tools for cognitive technology. (2001)

Blackwell,
A.F.,
Britton,
C.,
Cox,
A.L.,
...

A Closer Look At Exploratory Learning of Interactive Devices. (2001)

Cox,
A.L.,
Young,
R.M.

Selective trapping of organochlorine compounds in mountain lakes of temperate areas (2001)

Grimalt,
J.O.,
Fernandez,
P.,
Berdie,
L.,
...

Pro-inflammatory - anti-inflammatory cytokine dynamics mediated by cytokine-receptor dynamics in monocytes (2001)

Seymour,
R.M.,
Henderson,
B.

Many of the major human diseases, both infectious (septic shock syndromes) and idiopathic (for example, rheumatoid arthritis), are driven by the production of the pro-inflammatory cytokines...

Langer mesomelic dysplasia and Leri-Weill dyschondrosteosis - novel SHOX mutations and clinical phenotypic spectrum (2001)