R. M. Gronostajski

Publication List Details

Period

2003 - 2008

Number

30

Co-Authors

The transcription factor gene Nfib is essential for both lung maturation and brain development (2005)

Steele-Perkins, G., Plachez, C., Butz, K. G., Yang, G. H., Bachurski, C. J., Kinsman, S. L., ...

The phylogenetically conserved nuclear factor I (NFI) gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that...

Abnormal development of forebrain midline glia and commissural projections in Nfia knockout mice (2003)

T. Shu, K.G. Butz, R.M. Gronostajski, L.J. Richards

This paper describes the identification of specific molecules required for callosal formation expressed by midline glial populations. Prior to this publication nothing was known about the role of an...

Abnormal development of forebrain midline glia and commissural projections in Nfia knockout mice (2003)

T. Shu, K.G. Butz, R.M. Gronostajski, L.J. Richards

This paper describes the identification of specific molecules required for callosal formation expressed by midline glial populations. Prior to this publication nothing was known about the role of an...

Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice (2003)

Shu, T. Z., Butz, K. G., Plachez, C., Gronostajski, R. M., Richards, L. J.

Nuclear factor I (NFI) genes are expressed in multiple organs throughout development (Chaudhry et al., 1997; for review, see Gronostajski, 2000). All four NFI genes are expressed in embryonic mouse...

Purification and properties of the inducible nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase from Chlorella sorokiniana.

Gronostajski, R M, Yeung, A T, Schmidt, R R

The nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase (NADP-GDH) of Chlorella sorokiniana was purified 260-fold to electrophoretic homogeneity in six steps. Depending on...

Regulation of initial rate of induction of nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase during the cell cycle of synchronous Chlorella.

Turner, K J, Gronostajski, R M, Schmidt, R R

When synchronous cells of the eucaryotic microorganism Chlorella sorokiniana growing in nitrate medium were challenged to synthesize an ammonium-inducible nicotinamide adenine dinucleotide...

Regulation of accumulation and turnover of an inducible glutamate dehydrogenase in synchronous cultures of Chlorella.

Israel, D W, Gronostajski, R M, Yeung, A T, Schmidt, R R

Earlier studies indicated that the gene of an ammonium-inducible glutamate dehydrogenase (GDH) was inducible throughout the cell cycle and was expressible shortly after replication early in the...

Site-specific DNA binding of nuclear factor I: effect of the spacer region.

Gronostajski, R M

Nuclear factor I (NFI) is a site-specific DNA binding protein required for the replication of adenovirus type 2 DNA in vitro and in vivo. To study sequence requirements for the interaction of NFI...

Analysis of nuclear factor I binding to DNA using degenerate oligonucleotides.

Gronostajski, R M

Nuclear factor I (NFI) binds tightly to DNA containing the consensus sequence TGG(N)6-7GCCAA. To study the role of the spacing between the TGG and GCCAA motifs, oligonucleotides homologous to the NFI...

Stimulation of transcription in vitro by binding sites for nuclear factor I.

Gronostajski, R M, Knox, J, Berry, D, Miyamoto, N G

Nuclear factor I (NFI) is a site-specific DNA binding protein required for the replication of adenovirus DNA in vitro and in vivo. We have examined the effect of natural and synthetic binding sites...

Isolation of human DNA sequences that bind to nuclear factor I, a host protein involved in adenovirus DNA replication.

Gronostajski, R M, Nagata, K, Hurwitz, J

Nuclear factor I is a 47,000-dalton protein isolated from human HeLa cells that is required for the in vitro replication of adenovirus DNA. This protein was previously shown to bind specifically to...

In vivo stimulation of a chimeric promoter by binding sites for nuclear factor I.

Knox, J J, Rebstein, P J, Manoukian, A, Gronostajski, R M

Nuclear factor I (NFI) is composed of a family of site-specific DNA-binding proteins which recognize a DNA-binding site with the consensus sequence TGGC/A(N)5GCCAA. Binding sites for NFI have...

Analysis of multiple forms of nuclear factor I in human and murine cell lines.

Goyal, N, Knox, J, Gronostajski, R M

Nuclear factor I (NFI) is a group of related site-specific DNA-binding proteins that function in adenovirus DNA replication and cellular RNA metabolism. We have measured both the levels and forms of...

Site-specific DNA binding of nuclear factor I: analyses of cellular binding sites.

Gronostajski, R M, Adhya, S, Nagata, K, Guggenheimer, R A, Hurwitz, J

Nuclear factor I is a cellular site-specific DNA-binding protein required for the efficient in vitro replication of adenovirus DNA. We have characterized human DNA sequences to which nuclear factor I...

Energy requirement for degradation of tumor-associated protein p53.

Gronostajski, R M, Goldberg, A L, Pardee, A B

A 53,000-dalton protein (p53) present in large amounts in several types of tumorigenic cells was rapidly degraded in nontumorigenic BALB/c 3T3 fibroblasts (t 1/2, approximately 0.5 h) but not in...

The FLP recombinase of the Saccharomyces cerevisiae 2 microns plasmid attaches covalently to DNA via a phosphotyrosyl linkage.

Gronostajski, R M, Sadowski, P D

The FLP recombinase, encoded by the 2 micron plasmid of Saccharomyces cerevisiae, promotes efficient recombination in vivo and in vitro between its specific target sites (FLP sites). It was...

Purification and properties of the inducible nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase from Chlorella sorokiniana.

Gronostajski, R M, Yeung, A T, Schmidt, R R

The nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase (NADP-GDH) of Chlorella sorokiniana was purified 260-fold to electrophoretic homogeneity in six steps. Depending on...

Regulation of initial rate of induction of nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase during the cell cycle of synchronous Chlorella.

Turner, K J, Gronostajski, R M, Schmidt, R R

When synchronous cells of the eucaryotic microorganism Chlorella sorokiniana growing in nitrate medium were challenged to synthesize an ammonium-inducible nicotinamide adenine dinucleotide...

Regulation of accumulation and turnover of an inducible glutamate dehydrogenase in synchronous cultures of Chlorella.

Israel, D W, Gronostajski, R M, Yeung, A T, Schmidt, R R

Earlier studies indicated that the gene of an ammonium-inducible glutamate dehydrogenase (GDH) was inducible throughout the cell cycle and was expressible shortly after replication early in the...

Site-specific DNA binding of nuclear factor I: effect of the spacer region.

Gronostajski, R M

Nuclear factor I (NFI) is a site-specific DNA binding protein required for the replication of adenovirus type 2 DNA in vitro and in vivo. To study sequence requirements for the interaction of NFI...

Analysis of nuclear factor I binding to DNA using degenerate oligonucleotides.

Gronostajski, R M

Nuclear factor I (NFI) binds tightly to DNA containing the consensus sequence TGG(N)6-7GCCAA. To study the role of the spacing between the TGG and GCCAA motifs, oligonucleotides homologous to the NFI...

Stimulation of transcription in vitro by binding sites for nuclear factor I.

Gronostajski, R M, Knox, J, Berry, D, Miyamoto, N G

Nuclear factor I (NFI) is a site-specific DNA binding protein required for the replication of adenovirus DNA in vitro and in vivo. We have examined the effect of natural and synthetic binding sites...

Isolation of human DNA sequences that bind to nuclear factor I, a host protein involved in adenovirus DNA replication.

Gronostajski, R M, Nagata, K, Hurwitz, J

Nuclear factor I is a 47,000-dalton protein isolated from human HeLa cells that is required for the in vitro replication of adenovirus DNA. This protein was previously shown to bind specifically to...

In vivo stimulation of a chimeric promoter by binding sites for nuclear factor I.

Knox, J J, Rebstein, P J, Manoukian, A, Gronostajski, R M

Nuclear factor I (NFI) is composed of a family of site-specific DNA-binding proteins which recognize a DNA-binding site with the consensus sequence TGGC/A(N)5GCCAA. Binding sites for NFI have...

Analysis of multiple forms of nuclear factor I in human and murine cell lines.

Goyal, N, Knox, J, Gronostajski, R M

Nuclear factor I (NFI) is a group of related site-specific DNA-binding proteins that function in adenovirus DNA replication and cellular RNA metabolism. We have measured both the levels and forms of...

Site-specific DNA binding of nuclear factor I: analyses of cellular binding sites.

Gronostajski, R M, Adhya, S, Nagata, K, Guggenheimer, R A, Hurwitz, J

Nuclear factor I is a cellular site-specific DNA-binding protein required for the efficient in vitro replication of adenovirus DNA. We have characterized human DNA sequences to which nuclear factor I...

Energy requirement for degradation of tumor-associated protein p53.

Gronostajski, R M, Goldberg, A L, Pardee, A B

A 53,000-dalton protein (p53) present in large amounts in several types of tumorigenic cells was rapidly degraded in nontumorigenic BALB/c 3T3 fibroblasts (t 1/2, approximately 0.5 h) but not in...

The FLP recombinase of the Saccharomyces cerevisiae 2 microns plasmid attaches covalently to DNA via a phosphotyrosyl linkage.

Gronostajski, R M, Sadowski, P D

The FLP recombinase, encoded by the 2 micron plasmid of Saccharomyces cerevisiae, promotes efficient recombination in vivo and in vitro between its specific target sites (FLP sites). It was...