SOME ASPECTS OF GENERAL ANAESTHESIA FOR CEREBRAL ANGIOGRAPHY (1968)
Bilateral carotid angiography was carried out in thirty-six unselected patients. Anaesthesia was induced with thiopentone and maintained with nitrous oxide, oxygen and halothane. Overall values for...
HAZARDS OF ENDOTRACHEAL ANAESTHESIA (1964)
The hazards of endotracheal anaesthesia have been reviewed. These have been considered in relation to direct laryngoscopy, intubation and extubation. Prevention of such complications has also been...
PLASMA HYDROCORTISONE CONCENTRATIONS IN RELATION TO ANAESTHESIA AND SURGERY (1963)
Pre-anaesthetic, pre-surgical and post-surgical concentrations of unconjugated plasma hydrocortisone were determined in eighteen patients by quantitative paper chromatography. The mean...
Mahajan, S, Lewis, R N, George, R, Sykes, B D, McElhaney, R N
The active transport of sodium ions in live Acholeplasma laidlawii B cells and in lipid vesicles containing the (Na+-Mg2+)-ATPase from the plasma membrane of this microorganism was studied by 23Na...
Lewis, R N, Pohle, W, McElhaney, R N
The thermotropic phase behavior of aqueous dispersions of dipalmitoylphosphatidylcholine (DPPC) and its 1,2-dialkyl, 1-acyl 2-alkyl and 1-alkyl 2-acyl analogs was examined by differential scanning...
Lewis, R N, McElhaney, R N, Monck, M A, Cullis, P R
Hydrocarbon chain conformational and orientational order in liquid-crystalline bilayers of the highly chain-asymmetric 1-O-eicosanoyl, 2-O-dodecanoyl and 1-O-decanoyl, 2-O-docosanoyl...
Lewis, R N, McElhaney, R N, Pohle, W, Mantsch, H H
Previous vibrational spectroscopic studies of solid acyl-alkyl and diacyl phosphatidylcholines suggested that the sn1- and sn2-carbonyl stretching modes of 1,2-diacylglycerolipids have different...
The mixed interdigitated gel phases of unlabeled, specifically 13C = O-labeled, and specifically chain-perdeuterated samples of 1-O-eicosanoyl, 2-O-lauroyl phosphatidylcholine and 1-O-decanoyl,...
The infrared dichroism of transmembrane helical polypeptides.
Axelsen, P H, Kaufman, B K, McElhaney, R N, Lewis, R N
Polarized attenuated total internal reflectance techniques were applied to study the infrared dichroism of the amide I transition moment in two membrane-bound peptides that are known to form oriented...
The subgel phases of unlabeled, specifically chain perdeuterated and specifically 13C = O labeled representative samples of the n-saturated diacylphosphatidylcholines were studied by...
Mannock, D A, Lewis, R N, McElhaney, R N, Akiyama, M, Yamada, H, Turner, D C, ...
We have studied the physical properties of aqueous dispersions of 1,2-sn- and 2,3-sn-didodecyl-beta-D-glucopyranosyl glycerols, as well as their diastereomeric mixture, using differential scanning...
The polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines was investigated by differential scanning calorimetry, 31P-nuclear magnetic resonance, and...
Lewis, R N, McElhaney, R N, Osterberg, F, Gruner, S M
Twelve saturated mixed-chain phosphatidylcholines have been identified for which the thermotropic phase behavior observed upon cooling from the L alpha phase is dependent upon the thermal history of...
McMullen, T P, Lewis, R N, McElhaney, R N
We have investigated the comparative effects of the incorporation of increasing quantities of androstenol and cholesterol on the thermotropic phase behavior of aqueous dispersions of members of a...
Lewis, R N, McElhaney, R N, Harper, P E, Turner, D C, Gruner, S M
We have synthesized a number of 1,2-diacyl phosphatidylcholines with hydrophobic substituents adjacent to the carbonyl group of the fatty acyl chain and studied their thermotropic phase behavior by...
Thermotropic phase behavior of phosphatidylcholines with omega-tertiary-butyl fatty acyl chains.
Lewis, R N, Mantsch, H H, McElhaney, R N
The thermotropic phase behavior of a homologous series of phosphatidylcholines containing acyl chains with omega-tertiary butyl groups was studied by differential scanning calorimetry, Fourier...
Zhang, Y P, Lewis, R N, Hodges, R S, McElhaney, R N
High-sensitivity differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopy were used to study the interaction of a synthetic alpha-helical hydrophobic transmembrane...
The lamellar/nonlamellar phase preferences of lipid model membranes composed of mixtures of several cationic lipids with various zwitterionic and anionic phospholipids were examined by a combination...
The thermotropic phase behavior of lipid bilayer model membranes composed of the even-numbered, N-saturated 1,2-diacyl phosphatidylserines was studied by differential scanning calorimetry and by...
McMullen, T P, Lewis, R N, McElhaney, R N
We have examined the effects of cholesterol on the thermotropic phase behavior and organization of aqueous dispersions of a homologous series of linear disaturated phosphatidylserines by...
Lewis, R N, Winter, I, Kriechbaum, M, Lohner, K, McElhaney, R N
Differential scanning calorimetry, x-ray diffraction, and infrared and (31)P-nuclear magnetic resonance ((31)P-NMR) spectroscopy were used to examine the thermotropic phase behavior and organization...
Harper, P E, Mannock, D A, Lewis, R N, McElhaney, R N, Gruner, S M
X-ray diffraction is used to solve the low-resolution structures of fully hydrated aqueous dispersions of seven different diacyl phosphatidylethanolamines (PEs) whose hydrocarbon chains have the same...
X-ray structure study of thermotropic phases in isoacylphosphatidylcholine multibilayers.
Church, S E, Griffiths, D J, Lewis, R N, McElhaney, R N, Wickman, H H
Structures of lamellar phases in aqueous dispersions of diisoacylphosphatidylcholines (17iPC and 20iPC) were determined by x-ray diffraction methods. In agreement with previous DSC studies, subgel,...
Mahajan, S, Lewis, R N, George, R, Sykes, B D, McElhaney, R N
The active transport of sodium ions in live Acholeplasma laidlawii B cells and in lipid vesicles containing the (Na+-Mg2+)-ATPase from the plasma membrane of this microorganism was studied by 23Na...
Lewis, R N, Pohle, W, McElhaney, R N
The thermotropic phase behavior of aqueous dispersions of dipalmitoylphosphatidylcholine (DPPC) and its 1,2-dialkyl, 1-acyl 2-alkyl and 1-alkyl 2-acyl analogs was examined by differential scanning...
Lewis, R N, McElhaney, R N, Monck, M A, Cullis, P R
Hydrocarbon chain conformational and orientational order in liquid-crystalline bilayers of the highly chain-asymmetric 1-O-eicosanoyl, 2-O-dodecanoyl and 1-O-decanoyl, 2-O-docosanoyl...
Lewis, R N, McElhaney, R N, Pohle, W, Mantsch, H H
Previous vibrational spectroscopic studies of solid acyl-alkyl and diacyl phosphatidylcholines suggested that the sn1- and sn2-carbonyl stretching modes of 1,2-diacylglycerolipids have different...
The mixed interdigitated gel phases of unlabeled, specifically 13C = O-labeled, and specifically chain-perdeuterated samples of 1-O-eicosanoyl, 2-O-lauroyl phosphatidylcholine and 1-O-decanoyl,...
The infrared dichroism of transmembrane helical polypeptides.
Axelsen, P H, Kaufman, B K, McElhaney, R N, Lewis, R N
Polarized attenuated total internal reflectance techniques were applied to study the infrared dichroism of the amide I transition moment in two membrane-bound peptides that are known to form oriented...
The subgel phases of unlabeled, specifically chain perdeuterated and specifically 13C = O labeled representative samples of the n-saturated diacylphosphatidylcholines were studied by...
Mannock, D A, Lewis, R N, McElhaney, R N, Akiyama, M, Yamada, H, Turner, D C, ...
We have studied the physical properties of aqueous dispersions of 1,2-sn- and 2,3-sn-didodecyl-beta-D-glucopyranosyl glycerols, as well as their diastereomeric mixture, using differential scanning...
The polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines was investigated by differential scanning calorimetry, 31P-nuclear magnetic resonance, and...
Lewis, R N, McElhaney, R N, Osterberg, F, Gruner, S M
Twelve saturated mixed-chain phosphatidylcholines have been identified for which the thermotropic phase behavior observed upon cooling from the L alpha phase is dependent upon the thermal history of...
McMullen, T P, Lewis, R N, McElhaney, R N
We have investigated the comparative effects of the incorporation of increasing quantities of androstenol and cholesterol on the thermotropic phase behavior of aqueous dispersions of members of a...
Lewis, R N, McElhaney, R N, Harper, P E, Turner, D C, Gruner, S M
We have synthesized a number of 1,2-diacyl phosphatidylcholines with hydrophobic substituents adjacent to the carbonyl group of the fatty acyl chain and studied their thermotropic phase behavior by...
Thermotropic phase behavior of phosphatidylcholines with omega-tertiary-butyl fatty acyl chains.
Lewis, R N, Mantsch, H H, McElhaney, R N
The thermotropic phase behavior of a homologous series of phosphatidylcholines containing acyl chains with omega-tertiary butyl groups was studied by differential scanning calorimetry, Fourier...
Zhang, Y P, Lewis, R N, Hodges, R S, McElhaney, R N
High-sensitivity differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopy were used to study the interaction of a synthetic alpha-helical hydrophobic transmembrane...
The lamellar/nonlamellar phase preferences of lipid model membranes composed of mixtures of several cationic lipids with various zwitterionic and anionic phospholipids were examined by a combination...
The thermotropic phase behavior of lipid bilayer model membranes composed of the even-numbered, N-saturated 1,2-diacyl phosphatidylserines was studied by differential scanning calorimetry and by...
McMullen, T P, Lewis, R N, McElhaney, R N
We have examined the effects of cholesterol on the thermotropic phase behavior and organization of aqueous dispersions of a homologous series of linear disaturated phosphatidylserines by...
Lewis, R N, Winter, I, Kriechbaum, M, Lohner, K, McElhaney, R N
Differential scanning calorimetry, x-ray diffraction, and infrared and (31)P-nuclear magnetic resonance ((31)P-NMR) spectroscopy were used to examine the thermotropic phase behavior and organization...
Harper, P E, Mannock, D A, Lewis, R N, McElhaney, R N, Gruner, S M
X-ray diffraction is used to solve the low-resolution structures of fully hydrated aqueous dispersions of seven different diacyl phosphatidylethanolamines (PEs) whose hydrocarbon chains have the same...
X-ray structure study of thermotropic phases in isoacylphosphatidylcholine multibilayers.
Church, S E, Griffiths, D J, Lewis, R N, McElhaney, R N, Wickman, H H
Structures of lamellar phases in aqueous dispersions of diisoacylphosphatidylcholines (17iPC and 20iPC) were determined by x-ray diffraction methods. In agreement with previous DSC studies, subgel,...