Tumours of uncertain tissue of origin were investigated by immunohistochemistry on formalin fixed paraffin embedded sections. Two antibodies--PD7/26, an anti common leucocyte antigen, and CAM5.2, an...
Severe diabetic microangiopathy with normal glucose tolerance and pituitary infarction.
Bilous, R W, Poston, R N, Keen, H, Viberti, G C
Blood glucose concentrations in a woman with severe retinopathy, nephropathy, and neuropathy were found to be within the normal range. A high random blood glucose concentration was recorded only...
Tumours of uncertain tissue of origin were investigated by immunohistochemistry on formalin fixed paraffin embedded sections. Two antibodies--PD7/26, an anti common leucocyte antigen, and CAM5.2, an...
Severe diabetic microangiopathy with normal glucose tolerance and pituitary infarction.
Bilous, R W, Poston, R N, Keen, H, Viberti, G C
Blood glucose concentrations in a woman with severe retinopathy, nephropathy, and neuropathy were found to be within the normal range. A high random blood glucose concentration was recorded only...
Interactions between soluble IgG, complement and cells in lymphocyte and monocyte ADCC.
The interactions of K lymphocyte- and monocyte-mediated ADCC (antibody-dependent cell-mediated cytotoxicity) systems with monomeric and aggregated IgG in solution are compared. K-lymphocyte ADCC is...
Detection of immune complexes in serum of patients with ankylosing spondylitis.
Corrigall, V, Panayi, G S, Unger, A, Poston, R N, Williams, B D
Immune complexes were measured in the sera of 18 patients iwth ankylosing spondylitis and 5 normal control subjects by their ability to inhibit antibody-mediated lymphocyte-induced cytotoxicity. 11...
Yanni, G, Nabil, M, Farahat, M R, Poston, R N, Panayi, G S
OBJECTIVES--Cytokines, released from mononuclear cells (MNC) are mediators of joint destruction in rheumatoid arthritis (RA). The mechanisms of action of gold salts used in the treatment of RA are...
Poston, R. N., Johnson-Tidey, R. R.
Blood-derived macrophages in the arterial intima are a characteristic feature of active atherosclerotic plaques. Adherent monocytes on the luminal surface and increased adhesion molecules on the...
Expression of intercellular adhesion molecule-1 in atherosclerotic plaques.
Poston, R. N., Haskard, D. O., Coucher, J. R., Gall, N. P., Johnson-Tidey, R. R.
Immunohistochemistry of human atherosclerotic arteries demonstrates expression of the intercellular adhesion molecule-1 (ICAM-1) on endothelial cells, macrophages, and smooth muscle cells of the...
Johnson-Tidey, R. R., McGregor, J. L., Taylor, P. R., Poston, R. N.
P-selectin (GMP-140) is an adhesion molecule present within endothelial cells that is rapidly translocated to the cell membrane upon activation, where it mediates endothelial-leukocyte interactions....
The binding of immunoglobulin Fc to cationic proteins.
The interaction of cationic proteins with IgG, IgA and IgM were investigated by solid phase radioimmunoassay. All these immunoglobulins showed avid binding, IgM giving the strongest reaction,...
Greenacre, S A B, Rocha, F A C, Rawlingson, A, Meinerikandathevan, S, Poston, R N, Ruiz, E, ...
We have examined the relationship between neutrophil accumulation, NO• production and nitrated protein levels in zymosan-mediated inflammation in rat skin in vivo.Rats were anaesthetized and...
Sousa, A. R., Trigg, C. J., Lane, S. J., Hawksworth, R., Nakhosteen, J. A., Poston, R. N., ...
BACKGROUND: Accumulating evidence suggests that the cytokine network is central to the immunopathology of bronchial asthma and the existence of naturally occurring cytokine antagonists has added to...