Reactive and non-reactive lymphocytes in experimental allergic encephalomyelitis.
Levinson, A I, Lisak, R P, Zweiman, B, Wilkerson, L D
Myelin basic protein (BP),induces an increased in vitro proliferative response of peritoneal exudate cells (PEC), compared with that given by pheripheral blood lymphocytes (PBL), in guinea-pigs with...
The immunohistology of the thymus in myasthenia gravis.
Kornstein, M. J., Brooks, J. J., Anderson, A. O., Levinson, A. I., Lisak, R. P., Zweiman, B.
We have investigated cell subpopulations in frozen sections of thymus tissue obtained from myasthenic (MG) and control subjects. With the use of an avidin-biotin immunoperoxidase system with...
Cerebrospinal fluid lymphocytes in experimental allergic encephalomyelitis.
Wilkerson, L D, Lisak, R P, Zweiman, B
We report characteristics of the cerebrospinal fluid (CSF) pleocytosis (616+/-148 cells/microliter) that occurred in guinea-pigs with definite clinical experimental allergic encephalomyelitis...
T and B lymphocytes in multiple sclerosis.
Lisak, R P, Levinson, A I, Zweiman, B, Abdou, N I
The percentage and total number of E and EAC rosettes, as indicators of T and B lymphocytes respectively, were studied in the blood of subjects with multiple sclerosis (MS) and normals. MS patients...
A new approach to the autoradiographic study of proliferating lymphocytes.
An adaptation of a cell filtration method for the autoradiographic study of cultured lymphocytes has been developed. The percentages of labelled cells are very similar in the filtered cell population...
Cold reactive antilymphocyte antibodies in neurological diseases.
Lisak, R P, Mercado, F, Zweiman, B
Cold reactive (15 degrees C) antilymphocyte antibodies were detected in the sera of 33% of patients with multiple sclerosis, 50% with Guillain-Barré syndrome, 42% with myasthenia gravis, and 38%...
Do patients with demyelinating disease have antibodies against human glial cells in their sera?
Cell-type-specific markers and indirect immunofluorescence were used to study immunoglobulin binding to glial cells in dissociated cell cultures of human foetal optic nerve, spinal cord and dorsal...
We have compared the lymphocyte in vitro proliferative response induced by muscle extract, phytohaemagglutinin, and pokeweed mitogen in peripheral blood lymphocytes of patients with myasthenia...
Serum immunogloblin levels in myasthenia gravis, polymyositis, and dermatomyositis.
Analyses of serum immunoglobulin (Ig) levels were performed in patients with myasthenia gravis, polymyositis and dermatomyositis, and in normal subjects. The mean IgG levels were elevated in the...
Antimyelin antibody in multiple sclerosis: no change during immunosuppression
Wilkerson, L. D., Lisak, R. P., Zweiman, B., Silberberg, D. H.
We studied retrospectively levels of antimyelin antibody in a group of 13 multiple sclerosis patients who underwent a clinical trial of long-term, high dose (2.0-4.5 mg/kg/day) azathiaprine therapy....