Gilbert, C. M., Filippich, L. J., McGeary, R. P., Charles, B.G.
The pharmacokinetics of doxorubicinol, a cytotoxic metabolite of the anticancer drug, doxorubicin, were studied in four healthy sulphur-crested cockatoos (Cacatua galerita) after a 20 min intravenous...
Pharmacokinetics of doxorubicinol in dogs (2006)
Gilbert, C. M., Filippich, L. J., Mcgeary, R. P., Charles, B. G.
Facile synthesis of rhodamine esters using acetyl chloride in alcohol solution (2006)
Ross, J. A., Ross, B. P., Rubinsztein-Dunlop, H., McGeary, R. P.
The rhodamines are a highly fluorescent class of compound used in many different fields of research, from the lasing medium in dye lasers to biological stains and markers for cellular drug...
Rhodamine B pentyl ester and its methyl, ethyl, propyl, and butyl homologues (2006)
Ross, J, Ross, B P, Cosgrove, K. L., Rubinsztein-Dunlop, H, McGeary, R P
Liposaccharide based vaccine carrier adjuvant systems (2006)
Simerska, P, Bong, Y. K., McGeary, R P, Moyle, P. M., Toth, I
Determination of the anomeric configurations of 2,3,4,6-tetra-O-acetyl-D-mannopyranosyl azide (2006)
Cosgrove, K. L., Bernhardt, P. V., Ross, B. P., McGeary, R. P.
The structures of 2,3,4,6-tetra-O-acetyl-alpha-D-mannopyranosyl azide and 2,3,4,6-tetra-O-acetyl-beta-D-mannopyranosyl azide were determined using X-ray crystallographic and one-dimensional NOESY...
Gilbert, C. M., McGeary, R. P., Filippich, L. J., Norris, R. L. G., Charles, B. G.
A new microscale method is reported for the determination of doxorubicin and its active metabolite, doxorubicinol, in parrot plasma. Sample workup involved acetonitrile protein precipitation, ethyl...
Ross, B. P., Braddy, A. C., McGeary, R. P., Blanchfield, J. T., Prokai, L., Toth, I.
The co-administration of a drug with a penetration enhancer (PE) is one method by which the membrane permeability of a drug can be improved. To facilitate PE design, it is important that the...
Fibroblast growth factor 1: A key regulator of human adipogenesis (2004)
Hutley, L., Shurety, W., Newell, F. S., McGeary, R. P., Pelton, N. S., Grant, J. A., ...
Obesity, with its related problems, is recognized as the fastest growing disease epidemic facing the world, yet we still have limited insight into the regulation of adipose tissue mass in humans. We...
Nucleophilic substitution reactions of pyranose polytosylates (2004)
McGeary, R. P., Rasoul Amini, S., Tang, V. W. S., Toth, I.
The 2,3,4-tri-toluenesulfonate ester derivatives of the methyl pyranosides of L-arabinose, D-ribose, D-lyxose, and D-xylose have been prepared, and their substitution reactions with various...
Targeting adipocyte number as an obesity treatment (2004)
Hutley, L., Shurety, W., Newell, F. S., Grant, J.A., Whitehead, J. P., Prins, J. B., ...
Hansford, K. A., Reid, R. C., Clark, C. I., Tyndall, J. D. A., Whitehouse, M. W., Guthrie, T., ...
Few reported inhibitors of secretory phospholipase A(2) enzymes inhibit the IIa human isoform (hnpsPLA(2)-IIa) noncovalently at submicromolar concentrations. Herein, the simple chiral precursor...
Lipid and carbohydrate based adjuvant/carriers in immunology (2003)
McGeary, R. P., Olive, C., Toth, I.
This review discusses various issues regarding vaccines:what are they and how they work, safety aspects, the role of adjuvants and carriers in vaccination, synthetic peptides as immunogens, and new...
Liposaccharides in drug delivery (2002)
Toth, I., Blanchfield, J. T., McGeary, R. P., Ross, B. P., Chan, Y.
Lipid-core-peptides for vaccination: Structure-activity relationship (2002)
Toth, I., Horvath, A., McGeary, R. P., Hayman, W.A., Olive, C., Good, M. F.
Enhancing peptide delivery using lipoamino acids and liposaccharides. (2001)
Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F., Toth, I.
Synthetic vaccines: Enhanced immunogenicity of Streptococcus peptide epitopes. (2001)
Mcgeary, R. P., Schubert, A., Olive, C., Hayman, W., Good, M. F., Toth, I.
Synthetic vaccines containing multiple copies of group A streptococcus peptide epitopes. (2001)
Mcgeary, R. P., Schubert, A., Olive, C., Hayman, W., Good, M. F., Toth, I.
Carbohydrate-based templates for synthetic vaccines and drug delivery (2001)
McGeary, R. P., Jablonkai, I., Toth, I.
Methyl tetra-O-allyl, and tetra-O-[2-(tetrahydro-2H-pyranyl)oxy.-3-oxapentyl glucosides, and tetra-O-(cyanoethyl)galactosyl azide were converted into derivatives containing linkers with terminal...
McGeary, R. P., Wright, K., Toth, I.
The reactions of sodium benzoate with a series of trimesylates derived from glucosamine have been examined in an attempt to gain facile access to galactosamine analogues. Trimesylate 17, in which the...
Bourne, G. T., Golding, S. W., McGeary, R. P., Meutermans, W. D. F., Jones, A., Marshall, G. R., ...
Cyclic peptides are appealing targets in the drug-discovery process. Unfortunately, there currently exist no robust solid-phase strategies that allow the synthesis of large arrays of discrete cyclic...
Small peptides do not inhibit human non-pancreatic secretory phospholipase-A 2 (Type IIA) (2000)
Clark, C. I., Reid, R. C., McGeary, R. P., Schafer, K., Fairlie, D. P.
Peptidostarands: valence tautomers of cyclic peptides (1999)
Ab initio molecular orbital calculations, at the HF/6-31G* and MP2//HF/6-31G* levels of theory, have been performed on a hypothetical class of organic compound which we call peptidostarands. These...
Concerning the anti-arthritic action of cetyl myrisoleate in rats: an interim report (1999)
Whitehouse, M. W., McGeary, R. P.
The proposed arthro-preventive action of cetyl myristoleate, an OTC product sold as a nutritional supplement, could not be confirmed, using an almost identical bioassay (adjuvant-induced...