Clapp, B.R., Hirschfield, G.M., Storry, C., Gallimore, J.R., Stidwill, R.P., Singer, M., ...
Background: Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when...
Meier, O, Boucke, K, Hammer, S V, Keller, S, Stidwill, R P, Hemmi, S, ...
Adenovirus type 2 (Ad2) binds the coxsackie B virus Ad receptor and is endocytosed upon activation of the alphav integrin coreceptors. Here, we demonstrate that expression of dominant negative...
Trotman, L C, Mosberger, N, Fornerod, M, Stidwill, R P, Greber, U F
Adenovirus type 2 (Ad2) imports its DNA genome through the nuclear pore complex (NPC) of cells in interphase for viral production. Here we identify the NPC-filament protein CAN/Nup214 as a docking...
Nakano, M Y, Boucke, K, Suomalainen, M, Stidwill, R P, Greber, U F
Disassembly is a key event of virus entry into cells. Here, we have investigated cellular requirements for the first step of adenovirus type 2 (Ad2) disassembly, the release of the fibers. Although...
Intracellular Virus Trafficking Reveals Physiological Characteristics of the Cytoskeleton. (2000)
Virus particles that infect eukaryotic cells can take advantage of the cytoskeleton and associated motors to translocate through the cytoplasm. Depending on the virus, motor proteins are recruited...
Suomalainen, M, Nakano, M Y, Keller, S, Boucke, K, Stidwill, R P, Greber, U F
Adenovirus (Ad) enters target cells by receptor-mediated endocytosis, escapes to the cytosol, and then delivers its DNA genome into the nucleus. Here we analyzed the trafficking of fluorophore-tagged...
The role of the nuclear pore complex in adenovirus DNA entry. (1997)
Greber, U F, Suomalainen, M, Stidwill, R P, Boucke, K, Ebersold, M W, Helenius, A
Adenovirus targets its genome to the cell nucleus by a multistep process involving endocytosis, membrane penetration and cytoplasmic transport, and finally imports its DNA into the nucleus. Using an...
Nakano, M. Y., Boucke, K., Suomalainen, M., Stidwill, R. P., Greber, U. F.
Disassembly is a key event of virus entry into cells. Here, we have investigated cellular requirements for the first step of adenovirus type 2 (Ad2) disassembly, the release of the fibers. Although...
The role of the nuclear pore complex in adenovirus DNA entry.
Greber, U F, Suomalainen, M, Stidwill, R P, Boucke, K, Ebersold, M W, Helenius, A
Adenovirus targets its genome to the cell nucleus by a multistep process involving endocytosis, membrane penetration and cytoplasmic transport, and finally imports its DNA into the nucleus. Using an...
Cross, B A, Leaver, K D, Semple, S J, Stidwill, R P
The hypothesis that the fluctuations in carotid chemoreceptor discharge represent more than a simple proportional response to respiratory oscillations of Pa, CO2 has been examined. Simultaneous...
Cross, B A, Grant, B J, Guz, A, Jones, P W, Semple, S J, Stidwill, R P
1. The hypothesis that respiratory oscillations of arterial blood gas composition influence ventilation has been examined. 2. Phrenic motoneurone output recorded in the C5 root of the left phrenic...
Nakano, M. Y., Boucke, K., Suomalainen, M., Stidwill, R. P., Greber, U. F.
Disassembly is a key event of virus entry into cells. Here, we have investigated cellular requirements for the first step of adenovirus type 2 (Ad2) disassembly, the release of the fibers. Although...
The role of the nuclear pore complex in adenovirus DNA entry.
Greber, U F, Suomalainen, M, Stidwill, R P, Boucke, K, Ebersold, M W, Helenius, A
Adenovirus targets its genome to the cell nucleus by a multistep process involving endocytosis, membrane penetration and cytoplasmic transport, and finally imports its DNA into the nucleus. Using an...
Cross, B A, Leaver, K D, Semple, S J, Stidwill, R P
The hypothesis that the fluctuations in carotid chemoreceptor discharge represent more than a simple proportional response to respiratory oscillations of Pa, CO2 has been examined. Simultaneous...
Cross, B A, Grant, B J, Guz, A, Jones, P W, Semple, S J, Stidwill, R P
1. The hypothesis that respiratory oscillations of arterial blood gas composition influence ventilation has been examined. 2. Phrenic motoneurone output recorded in the C5 root of the left phrenic...