R. Stephens

Publication List Details

Period

1972 - 2009

Number

151

Co-Authors

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding (2009)

Cer, R. Z., Mudunuri, U., Stephens, R., Lebeda, F. J.

A new web-server tool estimates Ki values from experimentally determined IC50 values for inhibitors of enzymes and of binding reactions between macromolecules (e.g. proteins, polynucleic acids) and...

Edited by D.L. Stewart, Jr., J.C. Daley and R.L. Stephens 19 THE IMPORTANCE OF RECYCLING TO THE ENVIRONMENTAL PROFILE OF METAL PRODUCTS (2008)

K J. Martchek, R Stephens, J. C. Daley

This introductory presentation will highlight recent efforts to quantify the positive value of recycling metals such as aluminum, magnesium, lead, zinc, nickel and copper in relation to the three...

Simulations investigating the effect of a Deuterium-Tritium-ice coating on the motion of the gold cone surface in a re-entrant cone-guided fast ignition inertial confinement fusion capsule (2007)

Pasley, J., Stephens, R.

One- and two-dimensional multigroup radiation hydrodynamics simulations have been performed to investigate the motion of the gold plasma generated at the surface of the embedded gold cone in a...

Hadron energy reconstruction for the ATLAS calorimetry in the framework of the non-parametrical method (2006)

Akhmadaliev, S., Amaral, P., Ambrosini, G., Amorim, A., Anderson, K., Andrieux, M.L., ...

This paper discusses hadron energy reconstruction for the ATLAS barrel prototype combined calorimeter (consisting of a lead-liquid argon electromagnetic part and an iron-scintillator hadronic part)...

Photometric Survey of Binary Near-Earth Asteroids (2006)

Pravec, Petr, Scheirich, P., Kusnirak, P., Sarounova, L., Mottola, Stefano, Hahn, Gerhard, ...

Photometric data on 17 binary near-Earth asteroids (15 of them are certain detections, two are probables) were analysed and characteristic properties of the near-Earth asteroid (NEA) binary...

Transcriptomic response to differentiation induction (2006)

Patton, GW, Stephens, R, Sidorov, IA, Xiao, X, Lempicki, RA, Dimitrov, DS, ...

Abstract Background Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A common terminal...

Fast-electron transport and heating of solid targets in high-intensity laser interactions measured by K alpha fluorescence (2006)

Martinolli, E, Koenig, M, Baton, SD, Santos, JJ, Amiranoff, F, Batani, D, ...

We present experimental results on fast-electron energy deposition into solid targets in ultrahigh intensity laser-matter interaction. X-ray K alpha emission spectroscopy with absolute photon...

Advancing Equipment Reliability via a Natural Disaster Opportunities for Thinking Outside the Box (2006)

Stephens, R.

In 1991, the World Business Council for Sustainable Development (WBCSD) introduced “Eco- Efficiency” as a management strategy to link financial and environmental performance to create more value...

Advancing Equipment Reliability via a Natural Disaster Opportunities for Thinking Outside the Box (2006)

Stephens, R.

In 1991, the World Business Council for Sustainable Development (WBCSD) introduced “Eco- Efficiency” as a management strategy to link financial and environmental performance to create more value...

BMC Bioinformatics Methodology article Transcriptomic (2006)

Gw Patton, R Stephens, Ia Sidorov, X Xiao, Ra Lempicki, Ds Dimitrov, ...

© 2006 Patton et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License

Embedding graduate skills into a first year management course: theory, practice and reflection. (2006)

Green, W., Hammer, S., Stephens, R.

This paper explores both the theory and practice of embedding graduate skills within Griffith Business School Curricula. We reflect on our experience in running a pilot in Management Concepts: a...

Hadron energy reconstruction for the ATLAS calorimetry in the framework of the non-parametrical method (2002)

Akhmadaliev, S., Amaral, P., Ambrosini, G., Amorim, A., Anderson, K., Andrieux, M.L., ...

This paper discusses hadron energy reconstruction for the ATLAS barrel prototype combined calorimeter (consisting of a lead-liquid argon electromagnetic part and an iron-scintillator hadronic part)...

Hadron energy reconstruction for the ATLAS calorimetry in the framework of the non-parametrical method (2002)

Akhmadaliev, S., Amaral, P., Ambrosini, G., Amorim, A., Anderson, K., Andrieux, M.L., ...

This paper discusses hadron energy reconstruction for the ATLAS barrel prototype combined calorimeter (consisting of a lead-liquid argon electromagnetic part and an iron-scintillator hadronic part)...

On the Effect of Hydrogen Embrittlement on Fracture Properties of Steel. (2002)

Valanis,K. C., Hwang,S. T., Wu,H-C., Mielnik,E., Stephens,R.

In this report it is shown that the observed reduction in fatigue life as well as the exhaustion of ductility of uniform steel specimens due to the presence of interstitial hydrogen can be modelled...

Studies of electron isochoric heating and its applicability to fast ignition (2002)

Key, MH, Amiranoff, F, Andersen, C, Batani, D, Baton, SD, Cowan, T, ...

American Nuclear Society. Editors: BA Hammel, DD Meyerhofer, J Meyer-ter-Vehn and H Azechi, pp 373-377

turtles (2002)

Ecology Of, Emydid Turtlesp, R. Stephens, J. J. Wiens, Patrick R. Stephens, John J. Wiens

Ecological diversification is a central topic in ecology and evolutionary biology. We undertook the first comprehensive species-level phylogenetic analysis of Emydidae (an ecologically diverse group...

Two episodes of life-threatening anaphylaxis in the same patient to a chlorhexidine-sulphadiazine-coated central venous catheter (2001)

Stephens, R., Mythen, M., Kallis, P., Davies, D. W. L., Egner, W., Rickards, A.

Chlorhexidine allergy has been described in the literature, mainly in Japanese individuals. Most reactions have been limited to the skin, mild in severity and a result of chlorhexidine containing...

Hadronic shower development in iron-scintillator tile calorimetry (2000)

Amaral, P., Amorim, A., Anderson, K., Barreira, G., Benetta, R., Berglund, S R., ...

The lateral and longitudinal profiles of hadronic showers detected by a prototype of the ATLAS Iron-Scintillator Tile Hadron Calorimeter have been investigated. This calorimeter presents a unique...

Hadronic shower development in iron-scintillator tile calorimetry (2000)

Amaral, P., Amorim, A., Anderson, K., Barreira, G., Benetta, R., Berglund, S R., ...

The lateral and longitudinal profiles of hadronic showers detected by a prototype of the ATLAS Iron-Scintillator Tile Hadron Calorimeter have been investigated. This calorimeter presents a unique...

Sterile bred rats for studies involving septic challenges have differing levels of endogenous immunity to endotoxin core (2000)

Stephens, R., Rashid, M., Barclay, R., Stidwell, R., Singer, M., Brealey, D., ...

Background: Low levels of natural endogenous antibody to endotoxin core (EndoCAb) have been related to poor outcome after surgery1 2 and sepsis.3 Rats are often used in animal models of sepsis, but...

Hadronic Shower Development in Iron-Scintillator Tile Calorimetry (1999)

Amaral, P, Amorim, A, Anderson, K, Barreira, G, Benetta, R, Berglund, S, ...

The lateral and longitudinal profiles of hadronic showers detected by a prototype of the ATLAS Iron-Scintillator Tile Hadron Calorimeter have been investigated. This calorimeter uses a unique...

Refractory Metal Alloys and Composites for Space Power Systems. (1998)

Stephens, R., Petrasek, D. W., Titran, R. H.

This paper concerned mmc in some important way and contained information about, utilized, or discussed these subjects: basic topics:, data, mmc, mmc data materials and material types:, (w)f/nb-zr, nb...

Evaluation of Fermi Read-out of the ATLAS Tilecal Prototype (1998)

Agnvall, S, Ajaltouni, Ziad J, Albiol, F, Alifanov, A, Amaral, P, Amelin, D V, ...

Prototypes of the \fermi{} system have been used to read out a prototype of the \atlas{} hadron calorimeter in a beam test at the CERN SPS. The \fermi{} read-out system, using a compressor and a 40...

Evaluation of FERMI read-out of the ATLAS tilecal prototype (1998)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amelin, D., Amorim, A., ...

Prototypes of the FERMI system have been used to read out a prototype of the ATLAS hadron calorimeter in a beam test at the CERN SPS. The FERMI read-out system, using a compressor and a 40 MHz...

Evaluation of FERMI read-out of the ATLAS tilecal prototype (1998)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amelin, D., Amorim, A., ...

Prototypes of the FERMI system have been used to read out a prototype of the ATLAS hadron calorimeter in a beam test at the CERN SPS. The FERMI read-out system, using a compressor and a 40 MHz...

Evaluation of FERMI read-out of the ATLAS tilecal prototype (1998)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amelin, D., Amorim, A., ...

Prototypes of the FERMI system have been used to read out a prototype of the ATLAS hadron calorimeter in a beam test at the CERN SPS. The FERMI read-out system, using a compressor and a 40 MHz...

Evaluation of FERMI read-out of the ATLAS tilecal prototype (1998)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amelin, D., Amorim, A., ...

Prototypes of the FERMI system have been used to read out a prototype of the ATLAS hadron calorimeter in a beam test at the CERN SPS. The FERMI read-out system, using a compressor and a 40 MHz...

Evaluation of FERMI read-out of the ATLAS tilecal prototype (1998)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amelin, D., Amorim, A., ...

Prototypes of the FERMI system have been used to read out a prototype of the ATLAS hadron calorimeter in a beam test at the CERN SPS. The FERMI read-out system, using a compressor and a 40 MHz...

Response of the ATLAS tile calorimeter prototype to muons (1997)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amorim, A., Anderson, K.J., ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1997)

Berger, E., Blair, R., Dawson, J., Fuess, T., Guarino, V., Hill, N., ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS. The differential probability ${\rm {d}}P/{\rm {d}}v$ per...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1997)

Ajaltouni, Z., Tisserand, V., Jezequel, S., Albiol, F., Alifanov, A., Amaral, P., ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

Response of the ATLAS tile calorimeter prototype to muons (1997)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amorim, A., Anderson, K.J., ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1997)

Berger, E., Blair, R., Dawson, J., Fuess, T., Guarino, V., Hill, N., ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS. The differential probability ${\rm {d}}P/{\rm {d}}v$ per...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1997)

Ajaltouni, Z., Tisserand, V., Jezequel, S., Albiol, F., Alifanov, A., Amaral, P., ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

Response of the ATLAS tile calorimeter prototype to muons (1997)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amorim, A., Anderson, K.J., ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1997)

Berger, E., Blair, R., Dawson, J., Fuess, T., Guarino, V., Hill, N., ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS. The differential probability ${\rm {d}}P/{\rm {d}}v$ per...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1997)

Ajaltouni, Z., Tisserand, V., Jezequel, S., Albiol, F., Alifanov, A., Amaral, P., ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1997)

Ajaltouni, Z., Tisserand, V., Jezequel, S., Albiol, F., Alifanov, A., Amaral, P., ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

Response of the ATLAS tile calorimeter prototype to muons (1997)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amorim, A., Anderson, K.J., ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1997)

Berger, E., Blair, R., Dawson, J., Fuess, T., Guarino, V., Hill, N., ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS. The differential probability ${\rm {d}}P/{\rm {d}}v$ per...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1997)

Ajaltouni, Z., Tisserand, V., Jezequel, S., Albiol, F., Alifanov, A., Amaral, P., ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

Response of the ATLAS tile calorimeter prototype to muons (1997)

Ajaltouni, Z., Albiol, F., Alifanov, A., Amaral, P., Amorim, A., Anderson, K.J., ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1997)

Berger, E., Blair, R., Dawson, J., Fuess, T., Guarino, V., Hill, N., ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS. The differential probability ${\rm {d}}P/{\rm {d}}v$ per...

Response of the ATLAS tile calorimeter prototype to muons (1996)

Ajaltouni, Ziad J, Albiol, F, Alifanov, A, Amaral, P, Amorim, A, Anderson, K J, ...

A study of high energy muons traversing the ATLAS hadron Tile calorimeter in the barrel region in the energy range between 10 and 300~GeV is presented. Both test beam experimental data and Monte...

Results from a combined test of an electromagnetic liquid argon calorimeter with a hadronic scintillating-tile calorimeter (1996)

Ajaltouni, Ziad J, Albiol, F, Alifanov, A, Amaral, P, Ambrosini, G, Amorim, A, ...

The first combined test of an electromagnetic liquid argon accordion calorimeter and a hadronic scintillating-tile calorimeter was carried out at the CERN SPS. These devices are prototypes of the...

A measurement of the energy loss spectrum of 150 GeV muons in iron (1996)

Berger, E, Blair, R, Dawson, J, Fuess, T A, Guarino, V, Hill, N, ...

The energy loss spectrum of 150 GeV muons has been measured with a prototype of the ATLAS hadron calorimeter in the H8 beam of the CERN SPS.\\ The differential probability $dP/dv$ per radiation...

Stream Processing II: An Alternative Algebraic Approach and the language ASTRAL (1995)

R. Stephens

We present a summary of [59] that develops the theoretical and practical tools necessary to provide a weak, second-order algebraic approach to stream processing. This research is in contrast to...

Stream Processing I: A Survey (1995)

R. Stephens

Stream processing is a term that is used widely in the literature to describe a variety of systems. We present an overview of the historical development of stream processing and a detailed discussion...

A Survey Of Stream Processing (1995)

R. Stephens

Stream processing is a term that is used widely in the literature to describe a variety of systems. We present an overview of the historical development of stream processing and a detailed discussion...

The New UA1 first level trigger processor (1988)

Bains, N, Charlton, DG, Ellis, N, Garvey, J, Gregory, J, Jimack, MP, ...

In *Trieste 1988, Proceedings, The impact of digital microelectronics and microprocessors on particle physics* 134-137.

Fast two-dimensional electromagnetic cluster finding in the new UA1 first level trigger processor (1988)

Bains, N, Baird, SA, Campell, D, Cawthraw, M, Charlton, DG, Coughlan, J, ...

In *Trieste 1988, Proceedings, The impact of digital microelectronics and microprocessors on particle physics* 274.

NON-LINEAR INTERACTION BETWEEN ULTRASONIC SHEAR WAVES AND DISLOCATIONS IN ALUMINIUM (1981)

Wang, Y., Britton, W., Stephens, R.

Shear waves at a frequency of 4.83 MHz have been propagated along the axis of an aluminium crystal of high purity. The second and third harmonics arising from the interaction between the ultrasonic...

NON-LINEAR INTERACTION BETWEEN ULTRASONIC SHEAR WAVES AND DISLOCATIONS IN ALUMINIUM (1981)

Wang, Y., Britton, W., Stephens, R.

Shear waves at a frequency of 4.83 MHz have been propagated along the axis of an aluminium crystal of high purity. The second and third harmonics arising from the interaction between the ultrasonic...

NON-LINEAR INTERACTION BETWEEN ULTRASONIC SHEAR WAVES AND DISLOCATIONS IN ALUMINIUM (1981)

Wang, Y., Britton, W., Stephens, R.

Shear waves at a frequency of 4.83 MHz have been propagated along the axis of an aluminium crystal of high purity. The second and third harmonics arising from the interaction between the ultrasonic...

ATTENUATION OF WEAK SHOCK WAVES IN LIQUIDS (1972)

Smith, R., Stephens, R.

An electrodynamic transducer has been used to generate weak shock waves (peak pressures 10-100 atmospheres) in liquids. Any valid comparison of experimental and theoretical attenuation is shown to...

PIEZOELECTRICITY AND THE GROWTH OF ULTRASONICS (1972)

Stephens, R.

A brief introduction will be given to the discovery of piezoelectricity and the significant application made by Paul Langevin. Then follows an account of the search for and development of new...

THE POHLMAN CELL AND ITS USE IN HOLOGRAPHY (1972)

Lafferty, A., Stephens, R.

In this paper an account is given of a specific acoustical visualization device, called a «Pohlman cell», and its use in an acoustical holographic system. A comparison is later made between...

ATTENUATION OF WEAK SHOCK WAVES IN LIQUIDS (1972)

Smith, R., Stephens, R.

An electrodynamic transducer has been used to generate weak shock waves (peak pressures 10-100 atmospheres) in liquids. Any valid comparison of experimental and theoretical attenuation is shown to...

PIEZOELECTRICITY AND THE GROWTH OF ULTRASONICS (1972)

Stephens, R.

A brief introduction will be given to the discovery of piezoelectricity and the significant application made by Paul Langevin. Then follows an account of the search for and development of new...

THE POHLMAN CELL AND ITS USE IN HOLOGRAPHY (1972)

Lafferty, A., Stephens, R.

In this paper an account is given of a specific acoustical visualization device, called a «Pohlman cell», and its use in an acoustical holographic system. A comparison is later made between...

ATTENUATION OF WEAK SHOCK WAVES IN LIQUIDS (1972)

Smith, R., Stephens, R.

An electrodynamic transducer has been used to generate weak shock waves (peak pressures 10-100 atmospheres) in liquids. Any valid comparison of experimental and theoretical attenuation is shown to...

PIEZOELECTRICITY AND THE GROWTH OF ULTRASONICS (1972)

Stephens, R.

A brief introduction will be given to the discovery of piezoelectricity and the significant application made by Paul Langevin. Then follows an account of the search for and development of new...

THE POHLMAN CELL AND ITS USE IN HOLOGRAPHY (1972)

Lafferty, A., Stephens, R.

In this paper an account is given of a specific acoustical visualization device, called a «Pohlman cell», and its use in an acoustical holographic system. A comparison is later made between...

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

Wiley, S, Gish, G D, Lai, V K, Stephens, R, White, M F, ...

The Shc adaptor protein contains two phosphotyrosine [Tyr(P)]binding modules--an N-terminal Tyr(P) binding (PTB) domain and a C-terminal Src homology 2 (SH2) domain. We have compared the ability of...

Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing.

Martarano, L, Stephens, R, Rice, N, Derse, D

The cis- and trans-acting components of the Rev regulatory pathway employed by equine infectious anemia virus (EIAV) to regulate and coordinate viral gene expression were examined in complementation...

Enzyme immunoassay for detection of human immunodeficiency virus-specific immunoglobulin A antibodies.

Connor, E, Wang, Z, Stephens, R, Holland, B, Palumbo, P, McSherry, G, ...

Early diagnosis of human immunodeficiency virus (HIV) infection may be difficult in adults with acute or recent HIV infection and in infants with perinatally acquired HIV. Detection of HIV-specific...

New method for the removal of extraneous proteins from purified oncornaviruses.

Traul, K, Larson, D, Stephens, R, Wolff, J, Munch, K, Mayyasi, S

Conventional methods (i.e. gradient centrifugation) for the purification of oncornaviruses are usually not effective in complete removal of nonviral proteins. Such contaminants often prove to be a...

Improved recognition and quantitation technique for oncornaviruses.

Stephens, R, Traul, K, Woolf, D, Lowry, G, Lelek, J

A technique to recognize and quantitate oncornaviruses using perforated pointed BEEM capsules has been developed in our laboratory. Virus samples that presented problems in counting, or those which...

Workshop on perinatal exposure to dioxin-like compounds. I. Summary.

Lindström, G, Hooper, K, Petreas, M, Stephens, R, Gilman, A

An international workshop reviewed 20 ongoing or recently completed studies of the effects of perinatal exposures to dioxins, dibenzofurans, and PCBs on the reproductive, endocrine,...

The impact of providing incentives for attendance at AIDS prevention sessions.

Deren, S, Stephens, R, Davis, W R, Feucht, T E, Tortu, S

The research literature on AIDS prevention efforts contains many reports on the impact of intervention sessions. Little information is available, however, on the success of various strategies to...

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

Wiley, S, Gish, G D, Lai, V K, Stephens, R, White, M F, ...

The Shc adaptor protein contains two phosphotyrosine [Tyr(P)]binding modules--an N-terminal Tyr(P) binding (PTB) domain and a C-terminal Src homology 2 (SH2) domain. We have compared the ability of...

Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing.

Martarano, L, Stephens, R, Rice, N, Derse, D

The cis- and trans-acting components of the Rev regulatory pathway employed by equine infectious anemia virus (EIAV) to regulate and coordinate viral gene expression were examined in complementation...

Enzyme immunoassay for detection of human immunodeficiency virus-specific immunoglobulin A antibodies.

Connor, E, Wang, Z, Stephens, R, Holland, B, Palumbo, P, McSherry, G, ...

Early diagnosis of human immunodeficiency virus (HIV) infection may be difficult in adults with acute or recent HIV infection and in infants with perinatally acquired HIV. Detection of HIV-specific...

New method for the removal of extraneous proteins from purified oncornaviruses.

Traul, K, Larson, D, Stephens, R, Wolff, J, Munch, K, Mayyasi, S

Conventional methods (i.e. gradient centrifugation) for the purification of oncornaviruses are usually not effective in complete removal of nonviral proteins. Such contaminants often prove to be a...

Improved recognition and quantitation technique for oncornaviruses.

Stephens, R, Traul, K, Woolf, D, Lowry, G, Lelek, J

A technique to recognize and quantitate oncornaviruses using perforated pointed BEEM capsules has been developed in our laboratory. Virus samples that presented problems in counting, or those which...

The impact of providing incentives for attendance at AIDS prevention sessions.

Deren, S, Stephens, R, Davis, W R, Feucht, T E, Tortu, S

The research literature on AIDS prevention efforts contains many reports on the impact of intervention sessions. Little information is available, however, on the success of various strategies to...

Workshop on perinatal exposure to dioxin-like compounds. I. Summary.

Lindström, G, Hooper, K, Petreas, M, Stephens, R, Gilman, A

An international workshop reviewed 20 ongoing or recently completed studies of the effects of perinatal exposures to dioxins, dibenzofurans, and PCBs on the reproductive, endocrine,...

Soluble urokinase plasminogen activator receptor in plasma of patients with inflammatory rheumatic disorders: increased concentrations in rheumatoid arthritis

Slot, O., Brunner, N., Locht, H., Oxholm, P., Stephens, R.

OBJECTIVE—Urokinase type plasminogen activator (uPA) catalyses the formation of the proteolytic enzyme plasmin, which is involved in matrix degradation in the processes of tissue remodelling....

Smoking and occupational allergy in workers in a platinum refinery.

Venables, K. M., Dally, M. B., Nunn, A. J., Stevens, J. F., Stephens, R., Farrer, N., ...

OBJECTIVE--To test the hypothesis that smoking increases the risk of sensitisation by occupational allergens. DESIGN--Historical prospective cohort study. SETTING--Platinum refinery. SUBJECTS--91...

Rapid appearance of plasmin in tear fluid after ocular allergen exposure.

Salonen, E M, Lauharanta, J, Sim, P S, Stephens, R, Vaheri, A

Specific allergens were applied topically to the conjunctivae of 18 allergic patients. In cases with positive allergic reaction, proteolytic activity, identified as plasmin using zymographic analysis...

An investigation of the chest radiographs in a controlled trial of busulphan, cyclophosphamide, and a placebo after resection for carcinoma of the lung.

Stott, H, Stephens, R, Fox, W, Simon, G, Roy, D C

A standard series of radiographs of 588 patients allocated at random to treatment with busulphan (B patients), cyclophosphamide (C patients), or a placebo (P patients) for two years after surgery for...

Prenatal diagnosis of Wolman's disease.

Patrick, A D, Willcox, P, Stephens, R, Kenyon, V G

Amniocentesis was performed in the 15th week of a pregnancy at risk for Wolman's disease. The cultured amniotic fluid cells were found to have a severe deficiency of acid esterase activity consistent...

Antenatal diagnosis of Niemann-Pick disease in a twin pregnancy.

Donnai, P, Donnai, D, Harris, R, Stephens, R, Young, E, Campbell, S

An Ashkenazi Jewish woman had a child with Niemann-Pick disease in her first marriage. She subsequently remarried a man who was also heterozygous for the condition and conceived twins. Prenatal...

Abnormalities on neurological examination among sheep farmers exposed to organophosphorous pesticides.

Beach, J R, Spurgeon, A, Stephens, R, Heafield, T, Calvert, I A, Levy, L S, ...

OBJECTIVES: Organophosphates are effective pesticides which are frequently used in several agricultural settings. Although their acute effects are well characterised, it remains unclear whether long...

Factors affecting adherence of end-stage renal disease patients to an exercise programme.

Williams, A, Stephens, R, McKnight, T, Dodd, S

Recently it has been shown that regular exercise is both physiologically and psychologically beneficial to patients with end-stage renal disease (ESRD). However, ESRD patients traditionally have a...

Chemotherapy versus supportive care in advanced non-small cell lung cancer: improved survival without detriment to quality of life

Spiro, S, Rudd, R, Souhami, R, Brown, J, Fairlamb, D, Gower, N, ...

Background: In 1995 a meta-analysis of randomised trials investigating the value of adding chemotherapy to primary treatment for non-small cell lung cancer (NSCLC) suggested a small survival benefit...

Role of human neurobehavioural tests in regulatory activity on chemicals

Stephens, R., Barker, P.

Psychological performance tests have been used since the mid-1960s in occupational and environmental health toxicology. The interpretation of significantly different test scores in neurobehavioural...

Metachromatic leucodystrophy: review of 38 cases.

MacFaul, R, Cavanagh, N, Lake, B D, Stephens, R, Whitfield, A E

Clinical and laboratory features of 38 children suffering from metachromatic leucodystrophy (MLD) are reported. Twenty-four children with the late infantile form of MLD presented between ages 6 and...

Hunter's disease in a girl: association with X:5 chromosomal translocation disrupting the Hunter gene.

Mossman, J, Blunt, S, Stephens, R, Jones, E E, Pembrey, M

We describe a 3 year old girl with the typical clinical features of the X linked recessive condition, Hunter's disease. The diagnosis was confirmed by the pattern of urinary excretion of...

Estimation of the additional costs of chemotherapy for patients with advanced non-small cell lung cancer

Maslove, L, Gower, N, Spiro, S, Rudd, R, Stephens, R, West, P

Background: A large multicentre randomised trial, the Big Lung Trial, which in part compared supportive care with or without cisplatin-based chemotherapy in patients with advanced non-small cell lung...

Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells

STEPHENS, R, NDUNGU, F M, LANGHORNE, J

Antibodies and B cells are critical in the protective immune response to the blood stage of the malaria parasite, Plasmodium chabaudi. However, little is known about the development of memory B cells...

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

Cer, R. Z., Mudunuri, U., Stephens, R., Lebeda, F. J.

A new web-server tool estimates Ki values from experimentally determined IC50 values for inhibitors of enzymes and of binding reactions between macromolecules (e.g. proteins, polynucleic acids) and...

A simulated sequential analysis based on data from two MRC trials.

Donaldson, A. N., Whitehead, J., Stephens, R., Machin, D.

The motivation for proposing sequential methods for cancer clinical trials is presented, and the methodology examined by re-analysing two completed phase III cancer trials of the Lung Cancer Working...

Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer

Von Plessen, C, Bergman, B, Andresen, O, Bremnes, R M, Sundstrom, S, Gilleryd, M, ...

This randomised multicentre trial was conducted to establish the optimal duration of palliative chemotherapy in advanced non-small-cell lung cancer (NSCLC). We compared a policy of three vs six...