Disruption of methylarginine metabolism impairs vascular homeostasis (2007)
Leiper, J., Nandi, M., Torondel, B., Murray-Rust, J., Malaki, M., O'Hara, B., ...
Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA) are endogenously produced amino acids that inhibit all three isoforms of nitric oxide synthase (NOS)1. ADMA accumulates in various...
Disruption of methylarginine metabolism impairs vascular homeostasis. (2007)
Leiper, J., Nandi, M., Torondel, B., Murray-Rust, J., Malaki, M., O'Hara, B., ...
Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA) are endogenously produced amino acids that inhibit all three isoforms of nitric oxide synthase (NOS). ADMA accumulates in various...
Pulmonary hypertension in a GTP-cyclohydrolase 1 deficient mouse (2005)
Nandi, M., Miller, A., Stidwill, R., Jacques, T.S., Lam, A.J.A., Haworth, S., ...
Background— GTP-cyclohydrolase 1 (GTP-CH1) catalyzes the first step for the de novo production of tetrahydrobiopterin (BH4), a cofactor for nitric oxide synthase (NOS). The hyperphenylalaninemic...
Nitrosyl heme production compared in endotoxemic and hemorrhagic shock (2005)
Davies, N.A., Brealey, D.A., Stidwill, R., Singer, M., Svistunenko, D.A., Cooper, C.E.
We compared nitric oxide production and nitrosyl hemoglobin steady state concentrations during the early phases of endotoxemic and hemorrhagic shock of equivalent severity. Sprague–Dawley rats were...
Cross, Brenda A., Davey, A., Guz, A., Katona, P. G., Maclean, M., Murphy, K., ...
1. The ventilatory response to electrically induced `exercise' was studied in six chloralose-anaesthetized dogs. The on-transient and steady-state responses to `exercise' were compared in the same...
Cross, Brenda A., Davey, A., Guz, A., Katona, P. G., Maclean, M., Murphy, K., ...
1. The effect of electrically induced `exercise' on the respiratory oscillation of arterial pH was studied in chloralose-anaesthetized dogs with spinal cord transection at T8/9 (dermatome level T6/7).
Cross, Brenda A., Davey, A., Guz, A., Katona, P. G., Maclean, M., Murphy, K., ...
1. The ventilatory response to electrically induced `exercise' was studied in six chloralose-anaesthetized dogs. The on-transient and steady-state responses to `exercise' were compared in the same...
Cross, Brenda A., Davey, A., Guz, A., Katona, P. G., Maclean, M., Murphy, K., ...
1. The effect of electrically induced `exercise' on the respiratory oscillation of arterial pH was studied in chloralose-anaesthetized dogs with spinal cord transection at T8/9 (dermatome level T6/7).