R. Williams

Publication List Details

Period

1861 - 2009

Number

155

Co-Authors

Discovery of the Extremely Energetic Supernova 2008fz (2009)

Drake, A. J., Djorgovski, S. G., Prieto, J. L., Mahabal, A., Balam, D., Williams, R., ...

We report on the discovery and initial observations of the energetic type IIn supernova (SN), 2008fz. The optical energy emitted by SN 2008fz (based on the light curve over a 88 day period), is...

XMM-Newton observations of SDSS J143030.22$-$001115.1: an unusually flat spectrum AGN (2009)

Mathur, S., Golowacz, E. C., Williams, R., Pogge, R., Fields, D., Grupe, D.

We present XMM observations of the AGN SDSS 1430-0011. The low S/N spectrum of this source obtained in a snap shot Chandra observation showed an unusually flat continuum. With the follow up XMM...

First Results from the Catalina Real-Time Transient Survey (2009)

Drake, A. J., Djorgovski, S. G., Mahabal, A., Beshore, E., Larson, S., Graham, M. J., ...

We report on the results from the first six months of the Catalina Real-Time Transient Survey (CRTS). In order to search for optical transients (OTs) with timescales of minutes to years, the CRTS...

DINOFLAGELLATE CATEGORISATION BY ARTIFICIAL NEURAL NETWORK (DICANN) (2009)

Dr Beatriz Reguera, Pref Serena, Fonda Umani, Prof Thomas Parisini, ...

DiCANN is an advanced pattern recognition laboratory system that is being developed to automatically categorise marine HAB Dinoflagellate specimens. A prototype of the system demonstrated accurate...

Reciprocal scansion in Wordsworth's 'There was a boy' (2009)

Williams, R., Mason, E.

In this two-voiced paper, we conduct an experiment in ‘reciprocal scansion’: a process in which prosodic investigation and labelling becomes a site, not for fixing the terms of a poem's formal...

Management Control Systems for R&D Activities In Government Sector: A Case of Indonesia (2009)

Silaen, P., Williams, R.

Research and Development (R&D) organisation has different activity, employee's characteristics, goals, and planning system from a non-R&D organisation. It requires Management Control Systems...

Continuity of care in patients with cancer: development and evaluation of a complex intervention. (2009)

King, M., Jones, L., McCarthy, O., Rogers, M., Richardson, A., Williams, R., ...

High experienced continuity of care in patients with cancer is associated with lower needs for care, better quality of life and better psychological outcomes. We developed and evaluated an...

Management Control Systems for R&D Activities In Government Sector: A Case of Indonesia (2009)

Silaen, P., Williams, R.

Research and Development (R&D) organisation has different activity, employee's characteristics, goals, and planning system from a non-R&D organisation. It requires Management Control Systems (MCS)...

Management Control Systems for R&D Activities In Government Sector: A Case of Indonesia (2009)

Silaen, P., Williams, R.

Research and Development (R&D) organisation has different activity, employee's characteristics, goals, and planning system from a non-R&D organisation. It requires Management Control Systems...

Contemporary patterns of care and disease activity outcome in early rheumatoid arthritis: the ERAN cohort (2009)

Kiely, P., Williams, R., Walsh, D., Young, A.

Objectives. To report from the Early Rheumatoid Arthritis Network (ERAN), time from symptom onset to start of therapy, treatment choices and disease outcome in early RA. Methods. Patients with newly...

"'Our deep, dear silence": marriage and lyricism in the sonnets from the Portuguese (2009)

Williams, R.

Sonnet XLI of Elizabeth Barrett Browning's Sonnets from the Portuguese is candid about its ambition to write love poetry that will last: — Oh, to shoot My soul's full meaning into future years,...

New approaches to object classification in synoptic sky surveys (2008)

Donalek, C., Mahabal, A., Djorgovski, S. G., Marney, S., Drake, A., Glikman, E., ...

Digital synoptic sky surveys pose several new object classification challenges. In surveys where real-time detection and classification of transient events is a science driver, there is a need for an...

Downloaded from (2008)

K. Clarke, M. Hartswood, R. Procter, M. Rouncefield, R. Slack, R. Williams, ...

© 2002 SAGE Publications. All rights reserved. Not for commercial use or unauthorized distribution. Improving ‘knife to skin time’: process modelling and new technology in medical work

REFERENCES (2008)

D. Rumelhart, G. Hinton, R. Williams, Learning Internal Representation

In conclusion, the investigated v€ ( xw GO method has been applied to NN learning and the results from multiple (100) independent test runs have shown consistent and stable performance (although...

support for graphical input. The ACM Graphics Standard Planning (2008)

D. L. Weller, E. D. Carlson, G. M. Giddings, F. P. Palermo, R. Williams, S. N. Zilles

Pointing at items on a graphics display is one of the most useful methods of interacting with a system graphically. This paper ex-amines existing graphical support and lists requirements for...

NAS Experiences with a Prototype Cluster of Workstations (2008)

R. Williams, D. Yip

This paper discusses the year-long activity at NAS to implement a large, loose cluster of worksta-tions from the existing Silicon Graphics, Inc. (SGI) pool of systems. Issues related to establishing...

RECENT DEVELOPMENTS IN NASA PIEZOCOMPOSITE ACTUATOR TECHNOLOGY (2008)

W. Wilkie, D. Inman, J. High, R. Williams

In this paper, we present an overview of recent progress in the development of the NASA Macro-Fiber Composite (MFC) piezocomposite actuator device. This will include a brief history of the...

DynamicWEB: Adapting to concept drift in COBWEB (2008)

Scanlan, J, Hartnett, J, Williams, R

Examining concepts that change over time has been an active area of research within data mining. This paper presents a new method that functions in contexts where concept drift is present, while also...

A RFID Proximity Card Data Set (2008)

Mirowski, L, Hartnett, J, Williams, R, Gray, T

This technical report makes available an RFID proximity card data set. The data set is a record of the activity of proximity cards within a proximity card system that controls user access to parts of...

Application of the particle filter to tracking of fish in aquaculture research (2008)

Pinkiewicz, T, Williams, R, Purser, J

The analysis of fish movement as an indicator of fish behaviour plays an important role in aquaculture research. Currently observations are carried out manually using video recordings. In this paper...

Application of the particle filter to tracking of fish in aquaculture research (2008)

Pinkiewicz, T, Williams, R, Purser, J

The analysis of fish movement as an indicator of fish behaviour plays an important role in aquaculture research. Currently observations are carried out manually using video recordings. In this paper...

DynamicWEB: Adapting to concept drift and object drift in COBWEB (2008)

Scanlan, J, Hartnett, J, Williams, R

Examining concepts that change over time has been an active area of research within data mining. This paper presents a new method that functions in contexts where concept drift is present, while also...

DynamicWEB: A method for reconnaissance activity profiling (2008)

Scanlan, J, Hartnett, J, Williams, R

Port scan correlation aims to differentiate between benign and malicious scans. In this paper we will examine a new method of profiling port scan activity in an attempt to link different source IP...

Application of the particle filter to tracking of fish in aquaculture research (2008)

Pinkiewicz, T, Williams, R, Purser, J

The analysis of fish movement as an indicator of fish behaviour plays an important role in aquaculture research. Currently observations are carried out manually using video recordings. In this paper...

Routine glutamic acid decarboxylase autoantibody (GADA) testing: patients' perspective (2008)

Davies, H, Mannan, SB, Brophy, S, Williams, R

Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to...

Childhood overweight and obesity: is the gap closing the wrong way? (2008)

Brunt, H., Lester, N., Davies, G., Williams, R.

Background Obesity is a significant public health issue. Obese children have an increased risk of developing chronic adult diseases. Knowledge of socio-economic distribution trends in childhood...

Routine glutamic acid decarboxylase autoantibody (GADA) testing: patients' perspective (2008)

Davies, H, Mannan, SB, Brophy, S, Williams, R

Background. Latent autoimmune diabetes in adults (LADA) is a form of type 1 diabetes which in the UK is often diagnosed and treated as type 2 diabetes (T2D). People with LADA show slow progression to...

Phenylketonuria: An Inborn Error of Phenylalanine Metabolism (2008)

Williams, R., Mamotte, Cyril, Burnett, J.

Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine (Phe) metabolism resulting from deficiency of phenylalanine hydroxylase (PAH). Most forms of PKU and...

Dinophysis (2007)

Plankton Species, R. Simpson, P. F. Culverhouse, R. E. Ellis, R. Williams

this paper is part of an on--going research programme attempting to find a general classifier of marine phyto-- and zoo--plankton through the application of artificial neural network techniques, and...

Abstract The Hierarchical Architecture Design and Simulation (2007)

F. W. Howell, R. Williams, R. N. Ibbett

Environment (HASE) is a tool for modelling and simulating computer architectures. Using HASE, designers can create and explore architectural designs at different levels of abstraction through a...

Health Technology Assessment (2007)

N Waugh, G Scotl, P Mcnamee, M Gillett, A Brennan, E Goyder, ...

Screening for type 2 diabetes: literature review and economic modelling

Interactive visualisation techniques for data mining of satellite imagery (2007)

Welch, SJ, Lucieer, A, Williams, R

This study presents a new visualisation tool for classification of satellite imagery. Visualisation of feature space allows exploration of patterns in the image data and insight into the...

Interaction Rules: their place in collaboration software (2007)

Kildare, RA, Williams, R, Hartnett, J, Reimann, P

One major form of social capital that is central to the development of communities is the set of structures devoted to; norms of interaction, making these norms overt and regulating interaction. The...

Management Control Systems Framework for R&D Organisation: A New Approach (2007)

Silaen, P., Williams, R.

The Research and Development (R&D) organisations by the nature of business activities will have to deal with higher level of uncertainty than that of a non R&D organisation. This has an...

Multiple Classifier Object Detection with Confidence Measures (2007)

Horton, M, Cameron-Jones, M, Williams, R

This paper describes an extension to the Haar Classifier Cascade technique for object detection. Existing Haar Classifier Cascades are binary; the extension adds confidence measurement. This...

Interactive visualisation techniques for data mining of satellite imagery (2007)

Welch, SJ, Lucieer, A, Williams, R

This study presents a new visualisation tool for classification of satellite imagery. Visualisation of feature space allows exploration of patterns in the image data and insight into the...

Interaction Rules: their place in collaboration software (2007)

Kildare, RA, Williams, R, Hartnett, J, Reimann, P

One major form of social capital that is central to the development of communities is the set of structures devoted to; norms of interaction, making these norms overt and regulating interaction. The...

CT based classification of long spinal allograft fusion (2007)

Tan, G., Goss, Benjamin G., Thorpe, Paul L., Williams, R.

Abstract Anterior column reconstruction of the thoracolumbar spine by structural allograft has an increased potential for biological fusion when compared to synthetic reconstructive options....

Cardiovascular changes after pulmonary cement embolism: an experimental study in sheep (2007)

Krebs, Jorg, Aebli, Nikolaus, Goss, Benjamin G., Wilson, K., Williams, R., Ferguson, Stephen J.

BACKGROUND AND PURPOSE: Most cement leaks during vertebroplasty are asymptomatic, but pulmonary cement embolism has been reported to cause cardiovascular disturbances and even death. Adding...

CT based classification of long spinal allograft fusion (2007)

Tan, G., Goss, Benjamin G., Thorpe, Paul L., Williams, R.

Abstract Anterior column reconstruction of the thoracolumbar spine by structural allograft has an increased potential for biological fusion when compared to synthetic reconstructive options....

Cardiovascular changes after pulmonary cement embolism: an experimental study in sheep (2007)

Krebs, Jorg, Aebli, Nikolaus, Goss, Benjamin G., Wilson, K., Williams, R., Ferguson, Stephen J.

BACKGROUND AND PURPOSE: Most cement leaks during vertebroplasty are asymptomatic, but pulmonary cement embolism has been reported to cause cardiovascular disturbances and even death. Adding...

Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries (2006)

Abbott, B., Abbott, R., Adhikari, R., Ageev, A., Agresti, J., Ajith, P., ...

We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an...

Detecting Marine Animals in Underwater Video: Let's Start with Salmon. (2006)

Williams, R, Lambert, T, Kelsall, A, Pauly, T

Environmental Decision Support Systems (EDSS) constitute an important emerging technology for the management of marine environments and resources world-wide. A requirement for such systems is the...

Computational challenges in processing and analysis of full-watercolumn multibeam sonar data. (2006)

Buelens, B, Williams, R, Sale, AHJ, Pauly, T

Several multibeam sonar systems are now capable of collecting and recording data samples covering the full-watercolumn, not just the seabed. Such systems, while still facing hardware challenges such...

A Semi-Automated Line Tracing Technique for Monitoring Ice Margins in Antarctic Images (2006)

Collings, A, Williams, R, Young, Neal, Hyland, G

The current shape and rate of change of the margins of the Antarctic ice sheet are poorly known. Since polar regions are inhospitable, remotely sensed images provide an invaluable data source for...

An Online Tool for Learning Collaboration and Learning While Collaborating (2006)

Kildare, RA, Williams, R, Hartnett, J

Independent individuals are increasingly required to join as teams to complete online tasks. This impacts education in three ways . Firstly teachers increasingly set collaborative online tasks for...

Virtual Attribute Subsetting (2006)

Horton, M, Cameron-Jones, M, Williams, R

Attribute subsetting is a meta-classification technique, based on learning multiple base-level classifiers on projections of the training data. In prior work with nearest-neighbour base classifiers,...

A new model for classifying DNA code inspired by neural networks and FSA (2006)

Kang, BH, Kelarev, A, Sale, AHJ, Williams, R

This paper introduces a new model of classifiers CL(V,E,l,r) designed for classifying DNA sequences and combining the flexibility of neural networks and the generality of finite state automata. Our...

Artificial Intelligence techniques for marine video analysis (2006)

Fearn, RC, Williams, R, Cameron-Jones, M

Modern fisheries management for scallop fisheries requires accurate assessment of fish stocks and careful monitoring of marine habitats. Underwater video promises to provide a means of obtaining this...

Dynamic WEB: Profile correlation using COBWEB (2006)

Scanlan, J, Hartnett, J, Williams, R

Establishing relationships within a dataset is one of the core objectives of data mining. In this paper a method of correlating behaviour profiles in a continuous dataset is presented. The profiling...

Labeled directed graphs and FSA as classifiers of strings (2006)

Kelarev, A, Kang, BH, Sale, AHJ, Williams, R

The classical concept of a finite state automaton (FSA) has long been used in computer science to classify formal languages regarded as sets of strings. This paper surveys and unifies recent results...

Ethnicity recording in general practice computer systems (2006)

Kumarapeli, P., Stepaniuk, R., De Lusignan, S., Williams, R., Rowlands, G.

Background Ethnicity data in general practice (GP) computerized medical records can be utilized to audit equity in health care. Methods We evaluated a patient profiling project targeted to improve...

Ethnicity recording in general practice computer systems (2006)

Kumarapeli, P., Stepaniuk, R., De Lusignan, S., Williams, R., Rowlands, G.

Background Ethnicity data in general practice (GP) computerized medical records can be utilized to audit equity in health care. Methods We evaluated a patient profiling project targeted to improve...

Ethnicity recording in general practice computer systems (2006)

Kumarapeli, P., Stepaniuk, R., De Lusignan, S., Williams, R., Rowlands, G.

Background Ethnicity data in general practice (GP) computerized medical records can be utilized to audit equity in health care. Methods We evaluated a patient profiling project targeted to improve...

Virtual Observatory: From Concept to Implementation (2005)

Djorgovski, S. G., Williams, R.

We review the origins of the Virtual Observatory (VO) concept, and the current status of the efforts in this field. VO is the response of the astronomical community to the challenges posed by the...

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer (2005)

Williams, R, Cheong, K, Halani, N, Lin, V, Packham, D, ...

BACKGROUND & AIMS: Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by heterozygous germline sequence mutations of DNA mismatch repair genes, most frequently MLH1 or MSH2. A novel...

Genetic evidence for a distinct subtype of schizophrenia characterized by pervasive cognitive deficit (2005)

Hallmayer, J.F., Badcock, J., Dragovi, M., Howell, S., Michie, Patricia Therese, Rock, D., ...

A novel phenotyping strategy in schizophrenia, targeting different neurocognitive domains, neurobehavioral features, and selected personality traits, has allowed us to identify a homogeneous familial...

Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations (2005)

Kairupan, Carla F., Meldrum, C. J., Crooks, R., Milward, E. A., Spigelman, Allan David, Burgess, B., ...

The MYH gene has recently been shown to be associated with a recessive form of colorectal adenomatous polyposis. Two common mutations in the MYH gene have been identified that lend themselves to...

Model inversion for midwater multibeam backscatter data analysis (2005)

Buelens, B, Williams, R, Sale, AHJ, Pauly, T

A model of the multibeam echosounding process was developed. This model has now been used as the basis for the application of a model inversion technique, with the aim of analyzing midwater multibeam...

A scientific data mining approach to midwater multibeam echosounding for fisheries applications (2005)

Buelens, B, Williams, R, Sale, AHJ, Pauly, T

Midwater acoustic backscatter measurements collected by multibeam sonar offer new opportunities and challenges for fisheries applications. A scientific data mining technique to handle midwater...

Identifying Reconnaissance Activity: A Strategy for Network Defence (2005)

Scanlan, J, Hartnett, J, Williams, R

Over recent years there has been a massive increase in the need to build stronger and more effective defensive systems in many contexts due to the amplified threat of terrorism. Network security is...

Researching Solutions to the Sustainability and Environmental Challenges for Rice-based Cropping Systems in Southern Australia (2005)

Humphreys, E, Beecher, G, Christen, E, Williams, R, Xevi, E, Thompson, J, ...

The major threat to the sustainability of irrigated agriculture in the rice growing regions of the southern Australia is secondary salinisation as a result of rising watertables. Rice growing...

Learning through exchange about organic agriculture - case of Europe and Australia (2005)

Sriskandarajah, N., Mulley, R., Christie, M., Taji, A., Wals, A., Abbott, L., ...

LEAFSE is the catch word for an innovative program of exchange study for young Australians and Europeans, with organic agriculture as the focal point of their Masters level studies. Two years ago,...

Exploring the Time Domain with the Palomar-QUEST Sky Survey (2004)

Mahabal, A., Djorgovski, S.G., Graham, M., Williams, R., Granett, B., Bogosavljevic, M., ...

Discoveries in astronomy are often made through a systematic exploration of previously poorly covered regions of the observable parameter space [1,2]. In particular, exploration of the time...

Fate and behaviour of pesticides in farm ditches: sorption kinetic influence (2004)

Margoum, C., Gouy, V., Williams, R., Tissut, M.

/ L'étude menée au Cemagref en laboratoire et sur canal expérimental consiste à déterminer les cinétiques et isothermes d'adsorption de trois herbicides aux caractéristiques physico-chimiques...

A framework for scientific data mining in hydro-acoustic data sets. (2004)

Buelens, B, Williams, R, Sale, AHJ, Pauly, T

A data mining framework for handling large volumes of scientific hydro-acoustic measurements is proposed. The method is applicable to data collected by the new generation of multibeam echosounders,...

Expert Software Support for Ad-hoc Teams - Enabling Online Interaction Rules (2004)

Kildare, RA, Williams, R, Hartnett, J

An expert set of interaction rules may help to guide leaderless, transient teams of individuals that work online and asynchronously. Medical and engineering professionals as well as students fall...

Montage: A grid enabled image mosaic service for the national virtual observatory (2003)

G. B. Berriman, J. C. Good, A. C. Laity, A. Bergou, J. Jacob, D. S. Katz, ...

The architecture of Montage, which delivers custom science-grade astronomical images, was presented at ADASS XII. That architecture has been tested on 2MASS images computed on single processor Linux...

Double Shear Testing of Bolts (2003)

Aziz, N., Pratt, D., Williams, R.

Double shear testing was carried out on fully grouted and axially tensioned bolts installed in two different types of three piece concrete blocks. The purpose of the study was to examine the...

Re-useable Knowledge: Development of an Object Oriented Industrial KBS and a Collaborative Domain Ontology. (2003)

Crowther, P, Berner, G, Williams, R

Since the early eighties, there has been a gradual shift in the focus of development of knowledge based systems away from the rapid prototyping techniques that had previously prevailed, toward more...

Midwater acoustic modeling for multibeam sonar simulation (2003)

Buelens, B, Williams, R, Sale, AHJ, Pauly, T

Simulation and modeling software has been developed to generate synthetic midwater multibeam data. Essentially, the simulator can be considered as a virtual test tank. In order to develop multibeam...

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer (2003)

Kruijtzer, C. M. F., Boot, H., Beijnen, J. H., Lochs, H. L., Parnis, F. X., Planting, A. S. T., ...

Background: Pharmacokinetic study has shown that co-administration of cyclosporin A (CsA), which acts as a P-glycoprotein (P-gp) and CYP-3A blocker, resulted in an 8-fold increase in the systemic...

Reverse engineering the greek comic mask using photographic three-dimensional scanning and three dimensional printing (2003)

Steele, K.A.M., Williams, R.

The application of Rapid Prototyping (RP) to archaeology and cultural heritage is an exciting and growing field. Previous studies have documented the use of RP to assist in archaeological...

A four-stage index 2 Diagonally Implicit Runge-Kutta method (2002)

Williams, R., Burrage, K., Cameron, I., Kerr, M.

High index Differential Algebraic Equations (DAEs) force standard numerical methods to lower order. Implicit Runge-Kutta methods such as RADAU5 handle high index problems but their fully implicit...

Gas Content Testing for Outburst Management Compliance (2002)

Williams, R.

It is fundamentally important to make sure that compliance for mining is not issued on the basis of gas content tests that are inadequately located, deficient in frequency or in error. This paper...

An Automated Image Analysis System for Determining Sea-Ice Concentration and Cloud Cover from AVHRR Images of the Antarctic (2002)

Williams, R, Michael, KJ, Pendlebury, S, Crowther, P

The Australian Bureau of Meteorology operates a meteorological centre at the Casey station in East Antarctica. This centre is able to receive AVHRR data directly from the NOAA satellites and the...

Le rôle des fossés agricoles dans la dissipation des produits phytosanitaires (2001)

Margoum, C., Gouy, V., Williams, R., Smith, J.

The intensification of agriculture leads to nonpoint source pollution and contamination of surface water by pesticides. In order to limit this kind of pollution, many research programs have been...

Paracetamol hepatotoxicity and alcohol consumption in deliberate and accidental overdose (2000)

MAKIN, A., WILLIAMS, R.

We studied the relationship between alcohol consumption and hepatotoxicity related to paracetamol ingestion both in cases of overdose with suicidal intent and in cases where paracetamol was...

Correlation of MRI lesions with visual psychophysical deficit in secondary progressive multiple sclerosis (2000)

Caruana, P. A., Davies, M. B., Weatherby, S. J. M., Williams, R., Haq, N., Foster, D. H., ...

The aim of this work was, first, to clarify the nature of the relationship between the sensory deficit in the demyelinated visual pathway and morphological changes revealed by MRI and, secondly, to...

Report on the EU-US Workshop on Large Scientific Databases (1999)

Williams, R., Messina, P., Gagliardi, F., Darlington, J., Aloisio, G.

This joint workshop was set up under the auspices of the Joint European Commission/National Science Foundation Strategy Group that met in Budapest in September 1998. The meeting derived from a joint...

The Design of a Knowledge-Based Guidance System for an Intelligent Multiple Objective Decision Support System (Imodss (1999)

Th Australasian Conference, J. Lu, M. A. Quaddus, K. L. Poh, R. Williams

This paper describes a project that extends the multiple objective decision support system (MODSS) by offering knowledge-based guidance to an intelligent multiple objective decision support system...

A Technique for the Identification and Analysis of Icebergs in Synthetic Aperture Radar Images of Antarctica (1999)

Williams, R, Rees, G, Young, Neal

This paper describes an image analysis technique developed to identify icebergs depicted in synthetic aperture radar images of Antarctica and to determine the outlines of these icebergs. The...

Association of medical, physiological, behavioural and socio-economic factors with elevated mortality in men of Irish heritage in West Scotland (1999)

Abbotts, J, Williams, R, Smith, GD

Background: Men with patrilineal Irish descent from the immigrations of the nineteenth centuries have higher death rates from 'all-causes' and, specifically, cardiovascular disease (CVD) than the...

Pharmacological characterisation of endothelium-dependent relaxation in human radial artery: comparison with internal thoracic artery (1999)

Hamilton, C.A, Williams, R, Pathi, V, Berg, G, McArthur, K, McPhaden, A.R, ...

Objective: The aim of this study was to investigate the contribution of nitric oxide/prostanoid-independent pathways to endothelium-dependent vasorelaxation in human conduit arteries. Methods: Rings...

Dry weight carbon and nitrogen content of some euphausiids from the north Atlantic Ocean and the Celtic Sea (1999)

Lindley, J.A., Robins, D.B., Williams, R.

Euphausiids were identified, measured and then dried during a research cruise to sites in the north-eastern Atlantic Ocean and shelf waters of the Celtic Sea in late summer. The lengths of furcilia...

Telecommunication Standardisation - Do We Really Need the User? (1998)

Kai Jakobs, Rob Procter, Robin Williams, R Williams

This paper challenges such calls: first, it suggests that users are in no position to provide meaningful requirements on a new IT service from the outset, simply because of a lack of necessary...

Inscribing the workers: An experiment in factory discipline or the inculcation of manners? (1995)

Williams, R.

The establishment of the factory system during the beginning of the Industrial Revolution created a demand for labour. Labour that was unused to the confines and rigours of factory life. In an...

Management accounting practice and price calculation: Soho foundry (1995)

Williams, R.

When deciding upon the price to charge for one of their products the managers of the Soho Foundry in Birmingham placed great reliance upon the data stored in their accounting system. By the last...

The cost of power: Costing procedures at the Soho foundry (1995)

Williams, R.

The Soho Foundry, managed by James Watt jnr was an innovative manufacturer of steam engines, in the late eighteenth and early nineteenth centuries. This paper discusses the establishment of the...

Accounting for steam: The accounts of the Soho factory (1995)

Williams, R.

The accounting records of the Soho Foundry, an organisation set up in the late eighteenth century display a close similarity to modem accounting processes. This paper discusses the organisation of...

Perceptual Completion of Occluded Surfaces (1994)

R. Williams, Lance R. Williams, Edward M. Riseman, Steven W. Zucker, W. Richards Adrion

PERCEPTUAL COMPLETION OF OCCLUDED SURFACES February 1994 LANCE R. WILLIAMS B.S., Pennsylvania State University M.S., University of Massachusetts Amherst Ph.D., University of Massachusetts Amherst...

Liver damage: mechanisms and management (1994)

Sherman, D I N, Williams, R

Despite recent advances in our knowledge of the mechanisms of alcohol-induced liver damage, abstinence from alcohol and supportive measures remain the mainstays of management for the majority of...

Interferon-{alpha} therapy with and without interferon-{alpha} priming in patients with chronic hepatitis B infection (1993)

Catterall, A. P., King, R., Lau, J. Y. N., Daniels, H. M., Alexander, G. J. M., Murray-Lyon, I. M., ...

To determine whether a priming course of lymphoblastoid interferon-alpha (IFN-α) enhances the efficacy of subsequent IFN-α therapy in the treatment of chronic hepatitis B, a randomized trial was...

Detection of Hepatitis B Virus DNA Sequences in Liver in HBsAg Seronegative Patients with Liver Disease with and without Anti-HBc Antibodies (1991)

FAGAN, EA, DAVISON, FD, TROWBRIDGE, R, CARMAN, WF, SMITH, HM, TEDDER, R, ...

Excluding studies from Brechot and co-workers, little support has been found for a role of the hepatitis B virus in the pathogenesis of HBsAg seronegative patients with predominantly chronic liver...

Intracranial and Cerebral Perfusion Pressure Changes Before, During and Immediately After Orthotopic Liver Transplantation for Fulminant Hepatic Failure (1991)

KEAYS, R, POTTER, D, O'GRADY, J, PEACHEY, T, ALEXANDER, G, WILLIAMS, R

Several centres that perform liver transplantation for fulminant hepatic failure have experience of patients who have not regained consciousness despite adequate graft function. In some of these,...

Frequency of Asymptomatic Hepatitis Types B and C in an Inner City Community and Relation to Possible Risk Factors (1991)

KING, R, JOHNSON, PJ, WHITE, YS, SMITH, HM, WILLIAMS, R

The frequency of asymptomatic carriage of the hepatitis virus types B and C in an inner city area (South London) was assessed in a survey of 1002 subjects attending their General Practitioner for...

Procyclin, a stage-specific surface antigen of T.Brucei. (1989)

Roditi, I., Koenig, E., Dobbelaere, D., Williams, R.

UCLA Symp.Parasites: Molecular Biology, Drug and Vaccine Design, Keystone, Colo., April 3, 1989

The Goblin Quadtree (1988)

Williams, R.

The Goblin quadtree is a new and simple data structure for representing spatial information. It stores a single pointer for each block of four nodes and average values at non-terminal nodes, enabling...

SPECIFIC ANTIBODIES TO HALOTHANE-INDUCED LIVER ANTIGENS IN HALOTHANE-ASSOCIATED HEPATITIS (1987)

KENNA, J. G., NEUBERGER, J., WILLIAMS, R.

Antibodies to halothane-altered liver cell determinants (halothane antibodies) have previously been detected in serum of patients with fulminant hepatic failure after halothane anaesthesia. However,...

System D: A distributed system for availability (1982)

S. Andler, I. Dingy, C. Hauser, W. Kim, J. Meld, R. Williams

System D is a distributed transaction-processing system which addresses the problems of data integrity, system availability, and incremental growth. It is an experimental research vehicle and has...

HEPATIC DAMAGE AFTER EXPOSURE TO HALOTHANE IN MEDICAL PERSONNEL (1981)

NEUBERGER, J., VERGANI, D., MIELI-VERGANI, G., DAVIS, M., WILLIAMS, R.

Two surgeons, in whom liver damage developed after occupational exposure to sub-anaesthetic doses of halothane, were found to have a circulating antibody which reacted specifically with...

Vertical distribution and seasonal abundance of Aglantha digitale (O.F. Muller) (Coelenterata: Trachymedusae) and other planktonic coelenterates in the northeast Atlantic Ocean (1981)

Williams, R., Conway, D.V.P.

The vertical distribution and seasonal variability in abundance of the hydromedusa Aglantha digitale (O.F. Müller) and other coelenterates from the north-east Atlantic Ocean are described. The...

Non-obstructive Dilatation of the Intrahepatic Biliary Tree with Cholangitis (1972)

MURRAY-LYON, I. M., SHILKIN, K. B., LAWS, J. W., ILLING, R. C., WILLIAMS, R.

Dilatation of the intrahepatic biliary tree without mechanical obstruction and sometimes with similarly unexplained dilatation of the common bile duct may occur as an isolated developmental...

The comparative measurement of splenic blood flow using 133xenon and an electromagnetic flowmeter (1970)

Blendis, L. M., Roberts, V. C., Spiro, M., Williams, R.

Authors' synopsisMeasurements of the splenic blood flow in five greyhound dogs and one adult human undergoing splenectomy were performed using a 133Xenon clearance method and an electromagnetic...

Frequency of hepatic HBV-DNA in patients with cirrhosis and hepatocellular carcinoma: relation to serum HBV markers.

White, Y. S., Johnson, P. J., Davison, F., Williams, R.

As part of a larger study designed to investigate the interaction of factors such as cirrhosis and hepatitis B virus infection as aetiological agents in the development of hepatocellular carcinoma,...

Clinical efficacy and toxicity of standard dose adriamycin in hyperbilirubinaemic patients with hepatocellular carcinoma: relation to liver tests and pharmacokinetic parameters.

Johnson, P. J., Dobbs, N., Kalayci, C., Aldous, M. C., Harper, P., Metivier, E. M., ...

A standard dose of Adriamycin (60 mg m-2) was administered to 30 patients with inoperable hepatocellular carcinoma, 16 of whom were hyperbilirubinaemic (18-37 mumol l-1). The hyperbilirubinaemic...

Relationship between serum alpha-foetoprotein, cirrhosis and survival in hepatocellular carcinoma.

Johnson, P. J., Melia, W. M., Palmer, M. K., Portmann, B., Williams, R.

An analysis of survival time of 57 West European patients with hepatocellular carcinoma was carried out to define which of several possible factors (age, sex, cirrhosis and raised serum...

Use of arterial devascularization and cytotoxic drugs in 30 patients with the carcinoid syndrome.

Melia, W. M., Nunnerley, H. B., Johnson, P. J., Williams, R.

Thirty patients with symptoms of the carcinoid syndrome and other symptoms not controlled by pharmacological agents were analysed with respect to the value of various treatment measures used. Tumour...

Sex steroid receptor proteins in foetal, adult and malignant human liver tissue.

Iqbal, M. J., Wilkinson, M. L., Johnson, P. J., Williams, R.

Sex steroid receptor proteins were studied in human normal liver and hepatocellular carcinoma (HCC). Oestrogen receptor (ER) was detected in nucleosol and cytosol of 4 normal adult and 5 malignant...

Hyperthyroxinaemia in hepatocellular carcinoma: relation to thyroid binding globulin in the clinical and preclinical stages of the disease.

Alexopoulos, A., Hutchinson, W., Bari, A., Keating, J. J., Johnson, P. J., Williams, R.

Serum thyroxine was significantly higher in 59 patients with hepatocellular carcinoma than in normal subjects, patients with uncomplicated cirrhosis (48), or other primary tumours with or without...

A prospective randomised controlled trial of tamoxifen and cyproterone acetate in pancreatic carcinoma.

Keating, J. J., Johnson, P. J., Cochrane, A. M., Gazzard, B. G., Krasner, N., Smith, P. M., ...

In a prospective controlled clinical trial, 108 patients with pancreatic adenocarcinoma were randomly allocated to receive tamoxifen 20 mg b.d., cyproteron acetate 100 mg t.d.s. or no active...

Evaluation of models to predict BRCA germline mutations

Kang, H H, Williams, R, Leary, J, Ringland, C, Kirk, J, Ward, R

The selection of candidates for BRCA germline mutation testing is an important clinical issue yet it remains a significant challenge. A number of risk prediction models have been developed to assist...

The role of MYH and microsatellite instability in the development of sporadic colorectal cancer

Colebatch, A, Hitchins, M, Williams, R, Meagher, A, Hawkins, N J, Ward, R L

Biallelic germline mutations in MYH are associated with colorectal neoplasms, which develop through a pathway involving somatic inactivation of APC. In this study, we investigated the incidence of...

Development of a novel bi-specific monoclonal antibody approach for tumour targeting

Koumarianou, A A, Hudson, M, Williams, R, Epenetos, A A, Stamp, G W H

To overcome the disadvantages of bi-specific antibody methodologies in vivo, a novel antibody approach has been designed to improve tumour targeting and effector to target ratio. The technique...