Rachel J. Lundie

Blood-stage Plasmodium infection induces CD+ T lymphocytes to parasite-expressed antigens, largely regulated by CDα+ dendritic cells (2008)

Lundie, Rachel J., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lau, Lei Shong, ...

Although CD8+ T cells do not contribute to protection against the blood stage of Plasmodium infection, there is mounting evidence that they are principal mediators of murine experimental cerebral...

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and anti-viral immunity (2006)

Wilson, Nicholas S., Behrens, Georg M. N., Lundie, Rachel J., Smith, Christopher M., Waithman, Jason, Young, Louise, ...

The mechanisms responsible for the immunosuppression associated with sepsis or some chronic blood infections remain poorly understood. Here we show that infection with a malaria parasite (Plasmodium...

Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens

Young, Louise J., Wilson, Nicholas S., Schnorrer, Petra, Mount, Adele, Lundie, Rachel J., La Gruta, Nicole L., ...

When dendritic cells (DCs) encounter signals associated with infection or inflammation, they become activated and undergo maturation. Mature DCs are very efficient at presenting antigens captured in...

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8α+ dendritic cells

Lundie, Rachel J., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lau, Lei Shong, ...

Although CD8+ T cells do not contribute to protection against the blood stage of Plasmodium infection, there is mounting evidence that they are principal mediators of murine experimental cerebral...

IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection

Nie, Catherine Q., Bernard, Nicholas J., Norman, M. Ursula, Amante, Fiona H., Lundie, Rachel J., Crabb, Brendan S., ...

Plasmodium falciparum malaria causes 660 million clinical cases with over 2 million deaths each year. Acquired host immunity limits the clinical impact of malaria infection and provides protection...