Radhakrishnan Narayanan

Synaptic and genomic responses to JNK and AP-1 signaling in Drosophilaneurons (2005)

Etter, Paul D, Narayanan, Radhakrishnan, Navratilova, Zaneta, Patel, Chirag, Bohmann, Dirk, Jasper, Heinrich, ...

Abstract Background The transcription factor AP-1 positively controls synaptic plasticity at the Drosophila neuromuscular junction. Although in motor neurons, JNK has been shown to activate AP-1, a...

Evidence for cell autonomous AP1 function in regulation of Drosophilamotor-neuron plasticity (2003)

Sanyal, Subhabrata, Narayanan, Radhakrishnan, Consoulas, Christos, Ramaswami, Mani

Abstract Background The transcription factor AP1 mediates long-term plasticity in vertebrate and invertebrate central nervous systems. Recent studies of activity-induced synaptic change indicate that...

The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure

Okamoto, Ken-Ichi, Narayanan, Radhakrishnan, Lee, Sang H., Murata, Kazuyoshi, Hayashi, Yasunori

Ca2+-calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine protein kinase critically involved in synaptic plasticity in the brain. It is highly concentrated in the postsynaptic...

An internal GAP domain negatively regulates presynaptic dynamin in vivo: a two-step model for dynamin function

Narayanan, Radhakrishnan, Leonard, Marilyn, Song, Byeong Doo, Schmid, Sandra L., Ramaswami, Mani

The mechanism by which the self-assembling GTPase dynamin functions in vesicle formation remains controversial. Point mutations in shibire, the Drosophila dynamin, cause temperature-sensitive (ts)...