Rainer Strotmann

Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor (2009)

Thor, Doreen, Le Duc, Diana, Strotmann, Rainer, Schöneberg, Torsten

Abstract Background Controlling enzyme activity by ligand binding to a regulatory domain of choice may have many applications e.g. as biosensors and as tools in regulating cellular functions....

Parallel selection on TRPV6 in human populations (2008)

Tang, Kun, Strotmann, Rainer, Schöneberg, Torsten, Prenen, Jean, ...

We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel...

Parallel Selection on TRPV6 in Human Populations

Hughes, David A., Tang, Kun, Strotmann, Rainer, Schöneberg, Torsten, Prenen, Jean, Nilius, Bernd, ...

We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel...

Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation

Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...

Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...

Spino-dendritic cross-talk in rodent Purkinje neurons mediated by endogenous Ca2+-binding proteins

Schmidt, Hartmut, Kunerth, Svenja, Wilms, Christian, Strotmann, Rainer, Eilers, Jens

The range of actions of the second messenger Ca2+ is a key determinant of neuronal excitability and plasticity. For dendritic spines, there is on-going debate regarding how diffusional efflux of Ca2+...

Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation

Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...

Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...