TNF{alpha} shedding and epidermal inflammation are controlled by Jun proteins (2009)
Guinea-Viniegra, Juan, Zenz, Rainer, Scheuch, Harald, Hnisz, Denes, Holcmann, Martin, Bakiri, Latifa, ...
Inducible epidermal deletion of JunB and c-Jun in adult mice causes a psoriasis-like inflammatory skin disease. Increased levels of the proinflammatory cytokine TNFα play a major role in this...
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease (2008)
Zenz, Rainer, Eferl, Robert, Scheinecker, Clemens, Redlich, Kurt, Smolen, Josef, Schonthaler, Helia B, ...
Abstract Activator protein 1 (AP-1) (Fos/Jun) is a transcriptional regulator composed of members of the Fos and Jun families of DNA binding proteins. The functions of AP-1 were initially studied in...
Thesis (doctoral)--Johannes-Gutenberg-Universität Mainz, 1977.
Functions of c-Jun in Liver and Heart Development
Eferl, Robert, Sibilia, Maria, Hilberg, Frank, Fuchsbichler, Andrea, Kufferath, Iris, Guertl, Barbara, ...
Mice lacking the AP-1 transcription factor c-Jun die around embryonic day E13.0 but little is known about the cell types affected as well as the cause of embryonic lethality. Here we show that a...
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease
Zenz, Rainer, Eferl, Robert, Scheinecker, Clemens, Redlich, Kurt, Smolen, Josef, Schonthaler, Helia B, ...
Activator protein 1 (AP-1) (Fos/Jun) is a transcriptional regulator composed of members of the Fos and Jun families of DNA binding proteins. The functions of AP-1 were initially studied in mouse...
Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1
Eferl, Robert, Hasselblatt, Peter, Rath, Martina, Popper, Helmut, Zenz, Rainer, Komnenovic, Vukoslav, ...
Studies using genetically modified mice have revealed fundamental functions of the transcription factor Fos/AP-1 in bone biology, inflammation, and cancer. However, the biological role of the...