Rajat Varma

Actin and agonist MHC-peptide complex dependent T cell receptor microclusters as scaffolds for signaling.

Campi, Gabriele, Varma, Rajat, Dustin, Michael L.

TCR microclusters form within seconds of T cell contact with supported planar bilayers containing ICAM-1 and agonist MHC-peptide complexes and elevation of cytoplasmic Ca2+ is observed within seconds...

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling

Campi, Gabriele, Varma, Rajat, Dustin, Michael L.

T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and agonist major histocompatibility complex...

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

Kaizuka, Yoshihisa, Douglass, Adam D., Varma, Rajat, Dustin, Michael L., Vale, Ronald D.

T cells interacting with antigen-presenting cells (APCs) form an “immunological synapse” (IS), a bull's-eye pattern composed of a central supramolecular activation cluster enriched with T cell...