The Genome of the Natural Genetic Engineer Agrobacterium (2009)
Tumefaciens C, Derek W. Wood, Joao C. Setubal, Rajinder Kaul, Dave E. Monks, Joao P. Kitajima, ...
The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity...
Cone visual pigments of monotremes: Filling the phylogenetic gap (2008)
Wakefield, Matthew, Anderson, Mark, Chang, Ellen, Wei, Ke-Jun, Kaul, Rajinder, Marshall-Graves, Jennifer Mary, ...
Copyright © 2008 Cambridge University Press
Cone visual pigments of monotremes: Filling the phylogenetic gap (2008)
Wakefield, Matthew, Anderson, Mark, Chang, Ellen, Wei, Ke-Jun, Kaul, Rajinder, Marshall-Graves, Jennifer Mary, ...
Copyright © 2008 Cambridge University Press
Rohmer, Laurence, Fong, Christine, Abmayr, Simone, Wasnick, Michael, Larson Freeman, Theodore, Radey, Matthew, ...
Abstract Background Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica , rarely cause disease. To...
Population Stratification of a Common APOBEC Gene Deletion Polymorphism (2007)
Jeffrey M. Kidd, Tera L. Newman, Eray Tuzun, Rajinder Kaul, Evan E. Eichler
The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
The DNA sequence, annotation and analysis of human chromosome 3 (2006)
Muzny, Donna M., Scherer, Steven E., Kaul, Rajinder, Wang, Jing, Yu, Jun, ...
High-throughput genotyping of intermediate-size structural variation (2006)
Newman, Tera L., Rieder, Mark J., Morrison, V. Anne, Sharp, Andrew J., Smith, Joshua D., Sprague, L. James, ...
The contribution of large-scale and intermediate-size structural variation (ISV) to human genetic disease and disease susceptibility is only beginning to be understood. The development of...
High-throughput genotyping of intermediate-size structural variation (2006)
Newman, Tera L., Rieder, Mark J., Morrison, V. Anne, Sharp, Andrew J., Smith, Joshua D., Sprague, L. James, ...
The contribution of large-scale and intermediate-size structural variation to human genetic disease and disease susceptibility is only beginning to be understood. The development of high-throughput...
Pseudomonas Aeruginosa, David H. Spencer, Arnold Kas, Eric E. Smith, Christopher K. Raymond, Elizabeth H. Sims, ...
Whole-genome shotgun sequencing was used to study the sequence variation of three Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and one from an aquatic...
The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58 (2001)
Derek W. Wood, Joao C. Setubal, Rajinder Kaul, Dave E. Monks, Joao P. Kitajima, Vagner K. Okura, ...
ro- teobacterium of the family Rhizobiaceae and a member of the diverse Agrobacterium genus. A ubiquitous soil organism and etiological agent of the plant disease crown gall (1), A. tumefaciens...
Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa
Raymond, Christopher K., Sims, Elizabeth H., Kas, Arnold, Spencer, David H., Kutyavin, Tanya V., Ivey, Richard G., ...
The outer carbohydrate layer, or O antigen, of Pseudomonas aeruginosa varies markedly in different isolates of these bacteria, and at least 20 distinct O-antigen serotypes have been described....
Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa
Spencer, David H., Kas, Arnold, Smith, Eric E., Raymond, Christopher K., Sims, Elizabeth H., Hastings, Michele, ...
Whole-genome shotgun sequencing was used to study the sequence variation of three Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and one from an aquatic...
Comprehensive transposon mutant library of Pseudomonas aeruginosa
Jacobs, Michael A., Alwood, Ashley, Thaipisuttikul, Iyarit, Spencer, David, Haugen, Eric, Ernst, Stephen, ...
We have developed technologies for creating saturating libraries of sequence-defined transposon insertion mutants in which each strain is maintained. Phenotypic analysis of such libraries should...
Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa
Smith, Eric E., Sims, Elizabeth H., Spencer, David H., Kaul, Rajinder, Olson, Maynard V.
Pyoverdine is the primary siderophore of the gram-negative bacterium Pseudomonas aeruginosa. The pyoverdine region was recently identified as the most divergent locus alignable between strains in the...
Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells†
Miller, Daniel G., Trobridge, Grant D., Petek, Lisa M., Jacobs, Michael A., Kaul, Rajinder, Russell, David W.
The integration sites of viral vectors used in human gene therapy can have important consequences for safety and efficacy. However, an extensive evaluation of adeno-associated virus (AAV) vector...
Ancient haplotypes of the HLA Class II region
Raymond, Christopher K., Kas, Arnold, Paddock, Marcia, Qiu, Ruolan, Zhou, Yang, Subramanian, Sandhya, ...
Allelic variation in codons that specify amino acids that line the peptide-binding pockets of HLA's Class II antigen-presenting proteins is superimposed on strikingly few deeply diverged haplotypes....
Foamy virus vector integration sites in normal human cells
Trobridge, Grant D., Miller, Daniel G., Jacobs, Michael A., Allen, James M., Kiem, Hans-Peter, Kaul, Rajinder, ...
Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have performed a large-scale analysis of FV...
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
Smith, Eric E., Buckley, Danielle G., Wu, Zaining, Saenphimmachak, Channakhone, Hoffman, Lucas R., D’Argenio, David A., ...
In many human infections, hosts and pathogens coexist for years or decades. Important examples include HIV, herpes viruses, tuberculosis, leprosy, and malaria. With the exception of intensively...
Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa
Raymond, Christopher K., Sims, Elizabeth H., Kas, Arnold, Spencer, David H., Kutyavin, Tanya V., Ivey, Richard G., ...
The outer carbohydrate layer, or O antigen, of Pseudomonas aeruginosa varies markedly in different isolates of these bacteria, and at least 20 distinct O-antigen serotypes have been described....
Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa
Spencer, David H., Kas, Arnold, Smith, Eric E., Raymond, Christopher K., Sims, Elizabeth H., Hastings, Michele, ...
Whole-genome shotgun sequencing was used to study the sequence variation of three Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and one from an aquatic...
Comprehensive transposon mutant library of Pseudomonas aeruginosa
Jacobs, Michael A., Alwood, Ashley, Thaipisuttikul, Iyarit, Spencer, David, Haugen, Eric, Ernst, Stephen, ...
We have developed technologies for creating saturating libraries of sequence-defined transposon insertion mutants in which each strain is maintained. Phenotypic analysis of such libraries should...
Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa
Smith, Eric E., Sims, Elizabeth H., Spencer, David H., Kaul, Rajinder, Olson, Maynard V.
Pyoverdine is the primary siderophore of the gram-negative bacterium Pseudomonas aeruginosa. The pyoverdine region was recently identified as the most divergent locus alignable between strains in the...
Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells†
Miller, Daniel G., Trobridge, Grant D., Petek, Lisa M., Jacobs, Michael A., Kaul, Rajinder, Russell, David W.
The integration sites of viral vectors used in human gene therapy can have important consequences for safety and efficacy. However, an extensive evaluation of adeno-associated virus (AAV) vector...
Ancient haplotypes of the HLA Class II region
Raymond, Christopher K., Kas, Arnold, Paddock, Marcia, Qiu, Ruolan, Zhou, Yang, Subramanian, Sandhya, ...
Allelic variation in codons that specify amino acids that line the peptide-binding pockets of HLA's Class II antigen-presenting proteins is superimposed on strikingly few deeply diverged haplotypes....
Foamy virus vector integration sites in normal human cells
Trobridge, Grant D., Miller, Daniel G., Jacobs, Michael A., Allen, James M., Kiem, Hans-Peter, Kaul, Rajinder, ...
Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have performed a large-scale analysis of FV...
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
Smith, Eric E., Buckley, Danielle G., Wu, Zaining, Saenphimmachak, Channakhone, Hoffman, Lucas R., D’Argenio, David A., ...
In many human infections, hosts and pathogens coexist for years or decades. Important examples include HIV, herpes viruses, tuberculosis, leprosy, and malaria. With the exception of intensively...
Rohmer, Laurence, Brittnacher, Mitchell, Svensson, Kerstin, Buckley, Danielle, Haugen, Eric, Zhou, Yang, ...
Francisella tularensis is a bacterial pathogen that causes the zoonotic disease tularemia and is important to biodefense. Currently, the only vaccine known to confer protection against tularemia is a...
Population Stratification of a Common APOBEC Gene Deletion Polymorphism
Kidd, Jeffrey M, Newman, Tera L, Tuzun, Eray, Kaul, Rajinder, Eichler, Evan E
The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a...
A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate
Gallagher, Larry A., Ramage, Elizabeth, Jacobs, Michael A., Kaul, Rajinder, Brittnacher, Mitchell, Manoil, Colin
Francisella tularensis, the causative agent of tularemia, is one of the most infectious bacterial pathogens known and is a category A select agent. We created a sequence-defined, near-saturation...
Rohmer, Laurence, Fong, Christine, Abmayr, Simone, Wasnick, Michael, Larson Freeman, Theodore J, Radey, Matthew, ...
.Sequencing of the non-pathogenic Francisella tularensis sub-species novicida U112, and comparison with two pathogenic sub-species, provides insights into the evolution of pathogenicity in these...
Vuilleumier, Stéphane, Chistoserdova, Ludmila, Lee, Ming-Chun, Bringel, Françoise, Lajus, Aurélie, Zhou, Yang, ...
Wiens, Gregory D., Rockey, Daniel D., Wu, Zaining, Chang, Jean, Levy, Ruth, Crane, Samuel, ...
Renibacterium salmoninarum is the causative agent of bacterial kidney disease and a significant threat to healthy and sustainable production of salmonid fish worldwide. This pathogen is difficult to...