Ralph F. Tammariello

An alternative approach to combination vaccines: intradermal administration of isolated components for control of anthrax, botulism, plague and staphylococcal toxic shock (2008)

Morefield, Garry L, Tammariello, Ralph F, Purcell, Bret K, Worsham, Patricia L, Chapman, Jennifer, Smith, Leonard A, ...

Abstract Background Combination vaccines reduce the total number of injections required for each component administered separately and generally provide the same level of disease protection. Yet,...

Improved Formulation of a Recombinant Ricin A-Chain Vaccine Iincreases its Stability and Effective Antigenicity (2007)

Carra, John H., Wannemacher, Robert W., Tammariello, Ralph F., Lindsey, Changhong Y., Dinterman, Richard E., Schokman, Rowena D., ...

Ricin is a potent toxin associated with bioterrorism for which no vaccine or specific countermeasures are currently available. A stable, non-toxic and immunogenic recombinant ricin A-chain vaccine...

Improved stability of a protein vaccine through elimination of a partially unfolded state (2004)

McHugh, Colleen A., Tammariello, Ralph F., Millard, Charles B., Carra, John H.

Ricin is a potent toxin presenting a threat as a biological weapon. The holotoxin consists of two disulfide-linked polypeptides: an enzymatically active A chain (RTA) and a...

Improved stability of a protein vaccine through elimination of a partially unfolded state (2004)

McHugh, Colleen A., Tammariello, Ralph F., Millard, Charles B., Carra, John H.

Ricin is a potent toxin presenting a threat as a biological weapon. The holotoxin consists of two disulfide-linked polypeptides: an enzymatically active A chain (RTA) and a...

Maintenance and Transmission of Keystone Virus by Aedes atlanticus (Diptera: Culicidae) and the Gray Squirrel in the Pocomoke Cypress Swamp, Maryland, (1998)

Watts, Douglas M., Bailey, Charles L., Roberts, Nancy T., Tammariello, Ralph F., Dalrymple, Joel M.

Ecological studies were done in the Pocomoke Cypress Swamp, Worchester Co., MD., to clarify the role of Aedes atlanticus and gray Squirrels as enzootic hosts of Keystone (key) virus. Among 43...

Improved Stability of a Protein Vaccine Through Elimination of a Partially Unfolded State (1998)

McHugh, Colleen A., Tammariello, Ralph F., Millard, Charles B., Carra, John H.

Ricin is a potent toxin presenting a threat as a biological weapon. The holotoxin consists of two disulfide-linked polypeptides: an enzymatically active A chain (RTA) and a...

Improved stability of a protein vaccine through elimination of a partially unfolded state

McHugh, Colleen A., Tammariello, Ralph F., Millard, Charles B., Carra, John H.

Ricin is a potent toxin presenting a threat as a biological weapon. The holotoxin consists of two disulfide-linked polypeptides: an enzymatically active A chain (RTA) and a...