Ramakrishnan Nagaraj

Detecting the Site of Phosphorylation in Phosphopeptides Without Loss of Phosphate Group Using MALDI TOF Mass Spectrometry (9999)

Medicharla V. Jagannadham, Ramakrishnan Nagaraj

Phosphopeptides with one and four phosphate groups were characterized by MALDI mass spectrometry. The molecular ion of monophosphopeptide could be detected both as positive and negative ions by MALDI...

Detecting the Site of Phosphorylation in Phosphopeptides Without Loss of Phosphate Group Using MALDI TOF Mass Spectrometry (2008)

Medicharla V. Jagannadham, Ramakrishnan Nagaraj

Phosphopeptides with one and four phosphate groups were characterized by MALDI mass spectrometry. The molecular ion of monophosphopeptide could be detected both as positive and negative ions by MALDI...

Membrane Channel-forming Polypeptides. Aqueous Phase Aggregation and Membrane-Modifying Activity of Synthetic Fluorescent Alamethicin Fragments (1982)

Mathew, Mathew K, Nagaraj, Ramakrishnan, Balaram, Padmanabhan

Synthetic fragments of the membrane channel-forming polypeptide, alamethicin, have been labeled with a fluorescent 5-dimethylaminonaphthalene-1-sulfonyl (dansyl) group at the ${NH}_2$-terminal....

Membrane Channel-forming Polypeptides. Aqueous Phase Aggregation and Membrane-Modifying Activity of Synthetic Fluorescent Alamethicin Fragments (1982)

Mathew, Mathew K, Nagaraj, Ramakrishnan, Balaram, Padmanabhan

Synthetic fragments of the membrane channel-forming polypeptide, alamethicin, have been labeled with a fluorescent 5-dimethylaminonaphthalene-1-sulfonyl (dansyl) group at the ${NH}_2$-terminal....

The $3_{10}$ helical conformation of a pentapeptide containing \alpha-aminoisobutyric acid (Aib): X-ray crystal structure of $Tos-{(Aib)}_5-OMe$ (1978)

Shamala, Narayanaswamy, Nagaraj, Ramakrishnan, Balaram, Padmanabhan

The pentapeptide $Tos-{(Aib)}_5-OMe$ adopts a $3_{10}$ helical conformation in the solid state, with three consecutive Type III \beta-turns stabilised by intramolecular hydrogen bonds.

The $3_{10}$ helical conformation of a pentapeptide containing \alpha-aminoisobutyric acid (Aib): X-ray crystal structure of $Tos-{(Aib)}_5-OMe$ (1978)

Shamala, Narayanaswamy, Nagaraj, Ramakrishnan, Balaram, Padmanabhan

The pentapeptide $Tos-{(Aib)}_5-OMe$ adopts a $3_{10}$ helical conformation in the solid state, with three consecutive Type III \beta-turns stabilised by intramolecular hydrogen bonds.

Facile diketopiperazine formation from dipeptides containing a-aminoisobutyric acid. Conformational factors influencing Cyclisation (1977)

Nagaraj, Ramakrishnan, Balaram, Padmanabhan

Diketopiperazines were formed in good yields on deprotection of N-protected dipeptide esters containing a-aminoisobutyric acid residues. Cyclisation is likely to be favored by conformational...

Facile diketopiperazine formation from dipeptides containing a-aminoisobutyric acid. Conformational factors influencing Cyclisation (1977)

Nagaraj, Ramakrishnan, Balaram, Padmanabhan

Diketopiperazines were formed in good yields on deprotection of N-protected dipeptide esters containing a-aminoisobutyric acid residues. Cyclisation is likely to be favored by conformational...

Structure-Function Relationship Studies on the Frog Skin Antimicrobial Peptide Tigerinin 1: Design of Analogs with Improved Activity and Their Action on Clinical Bacterial Isolates

Sitaram, Narasimhaiah, Sai, Korrapati Purna, Singh, Shashi, Sankaran, Krishnan, Nagaraj, Ramakrishnan

Structure-function relationships in antimicrobial peptides have been extensively investigated in order to obtain improved analogs. Most of these studies have targeted either α-helical peptides or...

Antibacterial Activity of Human Neutrophil Defensin HNP-1 Analogs without Cysteines

Varkey, Jobin, Nagaraj, Ramakrishnan

The antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines has been investigated. A peptide corresponding to the HNP-1 sequence without the six cysteines (HNP-1ΔC)...

Structure-Function Relationship Studies on the Frog Skin Antimicrobial Peptide Tigerinin 1: Design of Analogs with Improved Activity and Their Action on Clinical Bacterial Isolates

Sitaram, Narasimhaiah, Sai, Korrapati Purna, Singh, Shashi, Sankaran, Krishnan, Nagaraj, Ramakrishnan

Structure-function relationships in antimicrobial peptides have been extensively investigated in order to obtain improved analogs. Most of these studies have targeted either α-helical peptides or...

Antibacterial Activity of Human Neutrophil Defensin HNP-1 Analogs without Cysteines

Varkey, Jobin, Nagaraj, Ramakrishnan

The antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines has been investigated. A peptide corresponding to the HNP-1 sequence without the six cysteines (HNP-1ΔC)...