Raman P. Singh

Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection (2007)

Van Rompay, Koen KA, Johnson, Jeffrey A, Blackwood, Emily J, Singh, Raman P, Lipscomb, Jonathan, Matthews, Timothy B, ...

Abstract Background We reported previously on the emergence and clinical implications of simian immunodeficiency virus (SIVmac251) mutants with a K65R mutation in reverse transcriptase (RT), and the...

Ultra-Reliability Evaluation Based on Multi-Property Degradation Mechanisms (1998)

Nakamura, Toshio, Singh, Raman P.

The reliability of composite materials when exposed to multiple degradation environments was characterized. First, a new procedure based on inverse analysis and experimental measurements was...

Nanoscale Characterization of Failure Processes in Polymer Nanocomposites (1998)

Singh, Raman P.

This project was focused on two areas of investigation: application of novel displacement modulation techniques for nanoindentation based viscoelastic characterization; and the use of acoustic...

CD8+-Cell-Mediated Suppression of Virulent Simian Immunodeficiency Virus during Tenofovir Treatment

Singh, Raman P., Pahar, Bapi, Sodora, Donald L., Wingfield, Casey, Lawson, Jonathan R., ...

The ability of tenofovir to suppress viremia in simian immunodeficiency virus (SIV)-infected macaques for years despite the presence of virulent viral mutants with reduced in vitro susceptibility is...

Structured Treatment Interruptions with Tenofovir Monotherapy for Simian Immunodeficiency Virus-Infected Newborn Macaques

Singh, Raman P., Heneine, Walid, Johnson, Jeffrey A., Montefiori, David C., Bischofberger, Norbert, ...

We demonstrated previously that prolonged tenofovir treatment of infant macaques, starting early during infection with virulent simian immunodeficiency virus (SIVmac251), can lead to persistently low...

CD8+-Cell-Mediated Suppression of Virulent Simian Immunodeficiency Virus during Tenofovir Treatment

Singh, Raman P., Pahar, Bapi, Sodora, Donald L., Wingfield, Casey, Lawson, Jonathan R., ...

The ability of tenofovir to suppress viremia in simian immunodeficiency virus (SIV)-infected macaques for years despite the presence of virulent viral mutants with reduced in vitro susceptibility is...

Structured Treatment Interruptions with Tenofovir Monotherapy for Simian Immunodeficiency Virus-Infected Newborn Macaques

Singh, Raman P., Heneine, Walid, Johnson, Jeffrey A., Montefiori, David C., Bischofberger, Norbert, ...

We demonstrated previously that prolonged tenofovir treatment of infant macaques, starting early during infection with virulent simian immunodeficiency virus (SIVmac251), can lead to persistently low...