Rasmus Larsen

Analysis of Surfaces Using Constrained Regression Models (2009)

Sune Darkner, Mert R. Sabuncu, Polina Goll, Rasmus R. Paulsen, Rasmus Larsen

Abstract. We present a study of the relationship between the changes in the shape of the human ear due to jaw movement and acoustical feedback (AF) in hearing aids. In particular, we analyze the...

Predictive Modelling of Cardiac 2D Multi-Slice MRI with Simultaneous Resolution of Cardiac and Respiratory Motion (2009)

Pedersen, Henrik, Ólafsdóttir, Hildur, Darkner, Sune, Lyksborg, Mark, Larsen, Rasmus

This paper introduces a novel approach to modelling of volumetric cardiac magnetic resonance imaging (MRI) with simultaneous resolution of cardiac and respiratory motion. The major challenge is that...

Predictive Modelling of Cardiac 2D Multi-Slice MRI with Simultaneous Resolution of Cardiac and Respiratory Motion (2009)

Pedersen, Henrik, Ólafsdóttir, Hildur, Darkner, Sune, Lyksborg, Mark, Larsen, Rasmus

This paper introduces a novel approach to modelling of volumetric cardiac magnetic resonance imaging (MRI) with simultaneous resolution of cardiac and respiratory motion. The major challenge is that...

Automated 3D Rigid Registration of Open 2D Manifolds (2008)

Sune Darkner, Martin Vester-christensen, Rasmus Larsen, Claus Nielsen, Rasmus R. Paulsen

Abstract — We present a robust method for 3D rigid registration of 2D open manifolds based on distance maps using an initialization step, a Gibbs sampler for optimization supplemented by an...

Sparse Statistical Deformation Model for the Analysis of Craniofacial Malformations in the Crouzon Mouse (2008)

Hildur Ólafsdóttir, Michael Sass Hansen, Tron A. Darvann, Nuno V. Hermann, Estanislao Oubel, Bjarne K. Ersbøll, ...

Abstract. Crouzon syndrome is characterised by the premature fusion of cranial sutures. Recently the first genetic Crouzon mouse model was generated. In this study, Micro CT skull scannings of...

Environmental Effects on Measurement Uncertainties of Time-of-Flight Cameras (2008)

Sigurjón Árni Guðmundsson, Henrik Aanæs, Rasmus Larsen

Abstract — In this paper the effect the environment has on the SwissRanger SR3000 Time-Of-Flight camera is investigated. The accuracy of this camera is highly affected by the scene it is pointed...

Int. J. Intelligent Systems Technologies and Applications, Vol. x, No. x, xxxx 1 Fusion of Stereo Vision and Time-of-Flight Imaging for Improved 3D Estimation (2008)

Sigurjón Árni Guðmundsson, Henrik Aanæs, Rasmus Larsen

Abstract: In this paper the fusion of two 3D estimation techniques is suggested: Stereo vision and Time-of-Flight (TOF) imaging. By converting the TOF-depth measurements to stereo disparities the...

Estimation of Motion Vector Fields (2008)

Rasmus Larsen

This paper presents an approach to the estimation of 2-D motion vector fields from time varying image sequences. We use a piecewise smooth model based on coupled vector/binary Markov random fields....

Some Issues of Biological Shape Modelling with Applications (2008)

Rasmus Larsen, Klaus Baggesen Hilger, Karl Skoglund, Sune Darkner, R. Paulsen, Mikkel B. Stegmann, ...

Abstract. This paper illustrates current research at Informatics and Mathematical Modelling at the Technical University of Denmark within biological shape modelling. We illustrate a series of...

Sparse Principal Component Analysis in Medical Shape Modeling (2008)

Karl Sjöstr, Mikkel B. Stegmann, Rasmus Larsen

Principal component analysis (PCA) is a widely used tool in medical image analysis for data reduction, model building, and data understanding and exploration. While PCA is a holistic approach where...

Classification of Biological Objects using Active Appearance Modelling and Color Cooccurrence Matrices (2008)

Anders Bjorholm Dahl, Henrik Aanæs, Rasmus Larsen, Bjarne Kjær

Abstract. We use the popular active appearance models (AAM) for extracting discriminative features from images of biological objects. The relevant discriminative features are combined principal...

Robust Pose Estimation using the SwissRanger SR-3000 Camera (2008)

Sigurjón Árni Guðmundsson, Rasmus Larsen, Bjarne K. Ersbøll

Abstract. In this paper a robust method is presented to classify and estimate an objects pose from a real time range image and a low dimensional model. The model is made from a range image training...

FIRST INTERNATIONAL WORKSHOP ON GENERATIVE MODEL-BASED VISION – GMBV 2002 101 Multi-band Modelling of Appearance (2008)

Mikkel B. Stegmann, Rasmus Larsen

Abstract — Earlier work has demonstrated generative models capable of synthesising near photo-realistic grey-scale images of objects. These models have been augmented with colour information, and...

On the Alignment of Shapes Represented by Fourier Descriptors (2008)

Karl Sjöstr, Anders Ericsson, Rasmus Larsen

The representation of shapes by Fourier descriptors is a time-honored technique that has received relatively little attention lately. Nevertheless, it has its benefits and is suitable for describing...

The Entire Regularization Path for the Support Vector Domain Description (2008)

Karl Sjöstr, Rasmus Larsen

Abstract. The support vector domain description is a one-class classification method that estimates the shape and extent of the distribution of a data set. This separates the data into outliers,...

Estimation of Fluid Flow Fields and Their Stagnation Points (2008)

Rasmus Larsen

In a topological sense fluid flows are characterised by their stagnation points. Given a temporal sequence of images of fluids we will consider the application of local polynomials to the estimation...

Wedgelet Enhanced Appearance Models (2008)

Sune Darkner, Rasmus Larsen, Mikkel B. Stegmann, Bjarne K. Ersbøll

Abstract — Statistical region-based segmentation methods such as the Active Appearance Model (AAM) are used for establishing dense correspondences in images based on learning the variation in shape...

Registration and shape modelling of porcine bone structures via CT (2008)

Søren G. Erbou, Rasmus Larsen, Bjarne K. Ersbøll

shape model of bone structures connected to the pelvic bone, fig. 1(a), is built. The shape model is used by the Danish Meat Research Institute (DMRI) to optimize and validate the functionality of a...

3-D Contextual Bayesian Classifiers (2008)

Rasmus Larsen

We extend a series of multivariate Bayesian 2-D contextual classifiers to 3-D by specifying a simultaneous Gaussian distribution for the feature vectorsaswell as a prior distribution of the class...

References (2008)

Rasmus Larsen

Optical flow The lecture on optical flow will be based on [2] and chapter 6 of [1].

Transcriptome Analysis of the Lactococcus lactis ArgR and AhrC Regulons (2008)

Larsen, Rasmus, Martinussen, Jan, Kuipers, Oscar P., Kok, Jan

In previous studies, we have shown that direct protein-protein interaction between the two regulators ArgR and AhrC in Lactococcus lactis is required for arginine-dependent repression of the...

Time-Resolved Determination of the CcpA Regulon of Lactococcus lactis subsp. cremoris MG1363 (2007)

Zomer, Aldert L., Buist, Girbe, Larsen, Rasmus, Kok, Jan, Kuipers, Oscar P.

Carbon catabolite control protein A (CcpA) is the main regulator involved in carbon catabolite repression in gram-positive bacteria. Time series gene expression analyses of Lactococcus lactis MG1363...

GlnR-Mediated Regulation of Nitrogen Metabolism in Lactococcus lactis (2006)

Larsen, Rasmus, Kloosterman, Tomas G., Kok, Jan, Kuipers, Oscar P.

We show that the nitrogen regulatory protein GlnR of Lactococcus lactis represses transcription of the amtB-glnK, glnRA, and glnPQ operons. This likely occurs through a conserved DNA motif,...

High-level heterologous production and functional expression of the sec-dependent enterocin P from Enterococcus faecium P13 in Lactococcus lactis (2006)

Gutiérrez, Jorge, Larsen, Rasmus, Cintas, Luis M., Kok, Jan, Hernández, Pablo E.

Enterocin P (EntP), a sec-dependent bacteriocin from Enterococcus faecium P13, was produced by Lactococcus lactis. The EntP structural gene (entP) with or without the EntP immunity gene (entiP) was...

Sparse modeling of landmark and texture variability using the orthomax criterion (2006)

Mikkel B. Stegmann, Karl Sjöstr, Rasmus Larsen

In the past decade, statistical shape modeling has been widely popularized in the medical image analysis community. Predominantly, principal component analysis (PCA) has been employed to model...

A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data (2005)

Van Hijum, Sacha AFT, De Jong, Anne, Baerends, Richard JS, Karsens, Harma A, Kramer, Naomi E, Larsen, Rasmus, ...

Abstract Background In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and...

A Generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data (2005)

De Jong, Anne, Baerends, Richard J.S., Karsens, Harma A., Kramer, Naomi E., Larsen, Rasmus, ...

Background: In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and robust...

A novel scheme to assess factors involved in the reproducibility of DNA-microarray data (2005)

Van Hijum, Sacha, De Jong, Anne, Baerends, Richard, Karsens, Harma A, Kramer, Naomi E, Larsen, Rasmus, ...

Abstract Background In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and...

Transcriptional regulation of central amino acid metabolism in Lactococcus lactis (2005)

Larsen, Rasmus

This thesis describes the functional characterisation of the transcriptional regulators GlnR, ArgR and AhrC of Lactococcus lactis, which are responsible for the control of genes involved in the...

Transcriptional regulation of central amino acid metabolism in Lactococcus lactis (2005)

Larsen, Rasmus

This thesis describes the functional characterisation of the transcriptional regulators GlnR, ArgR and AhrC of Lactococcus lactis, which are responsible for the control of genes involved in the...

A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. Methodology article (2005)

Jong, Anne De, Baerends,Richard J.S., Karsens, Harma A., Kramer, Naomi E., Larsen, Rasmus, ...

Background: In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and robust...

Interaction between ArgR and AhrC Controls Regulation of Arginine Metabolism in Lactococcus lactis (2005)

Larsen, Rasmus, Kok, Jan, Kuipers, Oscar P.

The expression of arginine metabolism in Lactococcus lactis is controlled by the two homologous transcriptional regulators ArgR and AhrC. Genome sequence analyses have shown that the occurrence of...

Probing Direct Interactions between CodY and the oppD Promoter of Lactococcus lactis (2005)

Hengst, Chris D. Den, Curley, Peter, Larsen, Rasmus, Buist, Girbe, Nauta, Arjen, Sinderen, Douwe Van, ...

CodY of Lactococcus lactis MG1363 is a transcriptional regulator that represses the expression of several genes encoding proteins of the proteolytic system. These genes include pepN, pepC, opp-pepO1,...

A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data (2005)

Hengst, Chris D. Den, Larsen, Rasmus, Kramer, Naomi E., Karsens, Harma A., Baerends, Richard J.S., Jong, Anne De, ...

Background: In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and robust...

A novel scheme to assess factors involved in the reproducibility of DNA-microarray data (2005)

Jong, Anne De, Baerends, Richard J.S., Karsens, Harma A., Kramer, Naomi E., Larsen, Rasmus, ...

Background: In research laboratories using DNA-microarrays, usually a number of researchers perform experiments, each generating possible sources of error. There is a need for a quick and robust...

ArgR and AhrC Are Both Required for Regulation of Arginine Metabolism in Lactococcus lactis (2004)

Larsen, Rasmus, Buist, Girbe, Kuipers, Oscar P., Kok, Jan

The DNA binding proteins ArgR and AhrC are essential for regulation of arginine metabolism in Escherichia coli and Bacillus subtilis, respectively. A unique property of these regulators is that they...

Multi-band modelling of appearance (2003)

Mikkel B. Stegmann, Rasmus Larsen

Abstract|Earlier work has demonstrated generative models capable of synthesising near photo-realistic grey-scale images of objects. These models have been augmented with colour information, and...

K.B.: Statistical 2D and 3D shape analysis using non-euclidean metrics (to appear). Medical Image Analysis (2003)

Rasmus Larsen, Klaus Baggesen Hilger, Mark C. Wrobel

Abstract. We address the problem of extracting meaningful, uncorrelated biological modes of variation from tangent space shape coordinates in 2D and 3D using non-Euclidean metrics. We adapt the...

STEGMANN et al.: FAME – A FLEXIBLE APPEARANCE MODELLING ENVIRONMENT 1 FAME – A Flexible Appearance Modelling Environment (2003)

Mikkel B. Stegmann, Bjarne K. Ersbøll, Rasmus Larsen, Mikkel B. Stegmann, Bjarne K. Ersbøll, Rasmus Larsen

Combined modelling of pixel intensities and shape has proven to be a very robust and widely applicable approach to interpret images. As such the Active Appearance Model (AAM) framework has been...

Decomposition using maximum autocorrelation factors (2002)

Rasmus Larsen

This article presents methods for the analysis and decomposition of multivariate datasets where a given ordering/structure of the observations or the variables exist. Examples of such data sets are...

A noise robust statistical texture model (2002)

Klaus B. Hilger, Mikkel B. Stegmann, Rasmus Larsen

Abstract. This paper presents a novel approach to the problem of obtaining a low dimensional representation of texture (pixel intensity) variation present in a training set after alignment using a...

Building and testing a statistical shape model of the human ear canal (2002)

Rasmus Paulsen, Rasmus Larsen, Claus Nielsen, Søren Laugesen, Bjarne Ersbøll

Abstract. Today the design of custom in-the-ear hearing aids is based on personal experience and skills and not on a systematic description of the variation of the shape of the ear canal. In this...

Q-MAF shape decomposition (2001)

Rasmus Larsen, Hrafnkell Eiriksson, Mikkel B. Stegmann

Abstract. This paper address the problems of generating a low dimensional representation of the shape variation present in a set of shapes represented by a number of landmark points. First, we will...

Supervised Mineral Classification with Semiautomatic Training and Validation Set Generation in Scanning Electron Microscope Energy Dispersive Spectroscopy Images of Thin Sections (1999)

Harald Flesche, Allan Aasbjerg Nielsen, Rasmus Larsen

This paper addresses the problem of classifying minerals common in siliciclastic and carbonate rocks. Twelve chemical elements are mapped from thin sections by energy dispersive spectroscopy in a...

Semi-automatic supervised classification of minerals from x-ray mapping images (1998)

Allan A. Nielsen, Harald Flesche, Rasmus Larsen, Johannes M. Rykkje, Mogens Ramm

This paper addresses the problem of classifying minerals common in siliciclastic and carbonate rocks. Twelve chemical elements are mapped from thin sections by energy dispersive spectroscopy (EDS) in...

Fusion of SPOT HRV XS and Orthophoto Data Using a Markov Random Field Model (1998)

Bjarne K. Ersbøll, Knut Conradsen, Rasmus Larsen, Allan A. Nielsen, Thomas H. Nielsen

: In remote sensing there is usually a trade-off between spatial resolution and spectral resolution. It is often desirable to present a combination of the data which merges the low resolution...

3-D Contextual Bayesian Classifiers (1997)

Rasmus Larsen, Rasmus Larsen

In this paper we will consider extensions of a series of Bayesian 2-D contextual classification pocedures proposed by Owen [1], Hjort & Mohn [2] and Welch & Salter [3] and Haslett [4] to 3...

3-DContextual Bayesian Classifiers (1997)

Rasmus Larsen, Rasmus Larsen

In this paper we will consider extensions of a series of Bayesian 2-D contextual classification pocedures proposed

Restoration Of Geris Data Using The Maximum Noise Fractions Transform (1994)

Allan Aasbjerg, Rasmus Larsen

The Maximum Noise Fractions (MNF) transformation is used as a restoration tool in a 512\Theta512 subscene of a 63 channel spectral dataset recorded over the Pyrite Belt in Southern Spain with the...

iv (1994)

Rasmus Larsen, Rasmus Larsen, Rasmus Larsen, Rasmus Larsen

This thesis has been prepared at the IMSOR group of the Institute of Mathematical

A Food-Grade Cloning System for Industrial Strains of Lactococcus lactis

Sørensen, Kim I., Larsen, Rasmus, Kibenich, Annette, Junge, Mette P., Johansen, Eric

We have previously reported the construction of a food-grade cloning vector for Lactococcus using the ochre suppressor, supB, as the selective marker. This vector, pFG1, causes only a slight growth...

ArgR and AhrC Are Both Required for Regulation of Arginine Metabolism in Lactococcus lactis

Larsen, Rasmus, Buist, Girbe, Kuipers, Oscar P., Kok, Jan

The DNA binding proteins ArgR and AhrC are essential for regulation of arginine metabolism in Escherichia coli and Bacillus subtilis, respectively. A unique property of these regulators is that they...

Probing Direct Interactions between CodY and the oppD Promoter of Lactococcus lactis

Den Hengst, Chris D., Curley, Peter, Larsen, Rasmus, Buist, Girbe, Nauta, Arjen, Van Sinderen, Douwe, ...

CodY of Lactococcus lactis MG1363 is a transcriptional regulator that represses the expression of several genes encoding proteins of the proteolytic system. These genes include pepN, pepC, opp-pepO1,...

GlnR-Mediated Regulation of Nitrogen Metabolism in Lactococcus lactis

Larsen, Rasmus, Kloosterman, Tomas G., Kok, Jan, Kuipers, Oscar P.

We show that the nitrogen regulatory protein GlnR of Lactococcus lactis represses transcription of the amtB-glnK, glnRA, and glnPQ operons. This likely occurs through a conserved DNA motif,...

A Food-Grade Cloning System for Industrial Strains of Lactococcus lactis

Sørensen, Kim I., Larsen, Rasmus, Kibenich, Annette, Junge, Mette P., Johansen, Eric

We have previously reported the construction of a food-grade cloning vector for Lactococcus using the ochre suppressor, supB, as the selective marker. This vector, pFG1, causes only a slight growth...

ArgR and AhrC Are Both Required for Regulation of Arginine Metabolism in Lactococcus lactis

Larsen, Rasmus, Buist, Girbe, Kuipers, Oscar P., Kok, Jan

The DNA binding proteins ArgR and AhrC are essential for regulation of arginine metabolism in Escherichia coli and Bacillus subtilis, respectively. A unique property of these regulators is that they...

Probing Direct Interactions between CodY and the oppD Promoter of Lactococcus lactis

Den Hengst, Chris D., Curley, Peter, Larsen, Rasmus, Buist, Girbe, Nauta, Arjen, Van Sinderen, Douwe, ...

CodY of Lactococcus lactis MG1363 is a transcriptional regulator that represses the expression of several genes encoding proteins of the proteolytic system. These genes include pepN, pepC, opp-pepO1,...

GlnR-Mediated Regulation of Nitrogen Metabolism in Lactococcus lactis

Larsen, Rasmus, Kloosterman, Tomas G., Kok, Jan, Kuipers, Oscar P.

We show that the nitrogen regulatory protein GlnR of Lactococcus lactis represses transcription of the amtB-glnK, glnRA, and glnPQ operons. This likely occurs through a conserved DNA motif,...

Time-Resolved Determination of the CcpA Regulon of Lactococcus lactis subsp. cremoris MG1363▿

Zomer, Aldert L., Buist, Girbe, Larsen, Rasmus, Kok, Jan, Kuipers, Oscar P.

Carbon catabolite control protein A (CcpA) is the main regulator involved in carbon catabolite repression in gram-positive bacteria. Time series gene expression analyses of Lactococcus lactis MG1363...

Transcriptome Analysis of the Lactococcus lactis ArgR and AhrC Regulons▿

Larsen, Rasmus, Martinussen, Jan, Kuipers, Oscar P., Kok, Jan

In previous studies, we have shown that direct protein-protein interaction between the two regulators ArgR and AhrC in Lactococcus lactis is required for arginine-dependent repression of the...

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

Seixas, Elsa, Gozzelino, Raffaella, Chora, Ângelo, Ferreira, Ana, Silva, Gabriela, Larsen, Rasmus, ...

Infection by Plasmodium, the causative agent of malaria, is associated with hemolysis and therefore with release of hemoglobin from RBC. Under inflammatory conditions, cell-free hemoglobin can be...