Read Pukkila-Worley

Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans (2002)

Alspaugh, J. Andrew, Pukkila-Worley, Read, Harashima, Toshiaki, Cavallo, Lora M., Funnell, Deanna L., Cox, Gary M., ...

The signaling molecule cyclic AMP (cAMP) is a ubiquitous second messenger that enables cells to detect and respond to extracellular signals. cAMP is generated by the enzyme adenylyl cyclase, which is...

Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans

Alspaugh, J. Andrew, Pukkila-Worley, Read, Harashima, Toshiaki, Cavallo, Lora M., Funnell, Deanna, Cox, Gary M., ...

The signaling molecule cyclic AMP (cAMP) is a ubiquitous second messenger that enables cells to detect and respond to extracellular signals. cAMP is generated by the enzyme adenylyl cyclase, which is...

Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade

Pukkila-Worley, Read, Gerrald, Quincy D., Kraus, Peter R., Boily, Marie-Josée, Davis, Matthew J., Giles, Steven S., ...

Cryptococcus neoformans is an opportunistic human fungal pathogen that elaborates several virulence attributes, including a polysaccharide capsule and melanin pigments. A conserved Gα protein/cyclic...

Chromosomal Translocation and Segmental Duplication in Cryptococcus neoformans†

Fraser, James A., Huang, Johnny C., Pukkila-Worley, Read, Alspaugh, J. Andrew, Mitchell, Thomas G., Heitman, Joseph

Large chromosomal events such as translocations and segmental duplications enable rapid adaptation to new environments. Here we marshal genomic, genetic, meiotic mapping, and physical evidence to...

Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans

Alspaugh, J. Andrew, Pukkila-Worley, Read, Harashima, Toshiaki, Cavallo, Lora M., Funnell, Deanna, Cox, Gary M., ...

The signaling molecule cyclic AMP (cAMP) is a ubiquitous second messenger that enables cells to detect and respond to extracellular signals. cAMP is generated by the enzyme adenylyl cyclase, which is...

Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade

Pukkila-Worley, Read, Gerrald, Quincy D., Kraus, Peter R., Boily, Marie-Josée, Davis, Matthew J., Giles, Steven S., ...

Cryptococcus neoformans is an opportunistic human fungal pathogen that elaborates several virulence attributes, including a polysaccharide capsule and melanin pigments. A conserved Gα protein/cyclic...

Chromosomal Translocation and Segmental Duplication in Cryptococcus neoformans†

Fraser, James A., Huang, Johnny C., Pukkila-Worley, Read, Alspaugh, J. Andrew, Mitchell, Thomas G., Heitman, Joseph

Large chromosomal events such as translocations and segmental duplications enable rapid adaptation to new environments. Here we marshal genomic, genetic, meiotic mapping, and physical evidence to...

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

Means, Terry K., Mylonakis, Eleftherios, Tampakakis, Emmanouil, Colvin, Richard A., Seung, Edward, Puckett, Lindsay, ...

Receptors involved in innate immunity to fungal pathogens have not been fully elucidated. We show that the Caenorhabditis elegans receptors CED-1 and C03F11.3, and their mammalian orthologues, the...