Oda, Mayumi, Glass, Jacob L., Thompson, Reid F., Mo, Yongkai, Olivier, Emmanuel N., Figueroa, Maria E., ...
Many genome-wide assays involve the generation of a subset (or representation) of the genome following restriction enzyme digestion. The use of enzymes sensitive to cytosine methylation allows...
Oligonucleotide Microarrays, Thomas J. Albert, Jason E. Norton, Michael N. Molla, Rebecca R. Selzer, Jaz Singh, ...
In this report we describe a rapid and cost effective comparative genomic strategy for mapping and identify single nucleotide polymorphisms, deletions and amplification across entire microbial...
Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...
Characterization of a recurrent 15q24 microdeletion syndrome (2007)
Sharp, Andrew J., Selzer, Rebecca R., Veltman, Joris A., Gimelli, Stefania, Gimelli, Giorgio, Striano, Pasquale, ...
We describe multiple individuals with mental retardation and overlapping de novo submicroscopic deletions of 15q24 (1.7–3.9 Mb in size). High-resolution analysis showed that in three patients both...
A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome (2007)
Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, ...
Submicroscopic (less than 2 Mb) segmental DNA copy number changes are a recently recognized source of genetic variability between individuals. The biological consequences of copy number variants...
Maydan, Jason S., Flibotte, Stephane, Edgley, Mark L., Lau, Joanne, Selzer, Rebecca R., Richmond, Todd A., ...
We have developed array Comparative Genomic Hybridization for Caenorhabditis elegans as a means of screening for novel induced deletions in this organism. We designed three microarrays consisting of...
Characterization of a recurrent 15q24 microdeletion syndrome (2007)
Sharp, Andrew J, Selzer, Rebecca R, Veltman, Joris A, Gimelli, Stefania, Gimelli, Giorgio, Striano, Pasquale, ...
We describe multiple individuals with mental retardation and overlapping de novo submicroscopic deletions of 15q24 (1.7-3.9 Mb in size). High resolution analysis showed that in three patients both...
Dostie, Josee, Richmond, Joann M., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Comparative isoschizomer profiling of cytosine methylation: The HELP assay (2006)
Khulan, Batbayar, Thompson, Reid F., Ye, Kenny, Fazzari, Melissa J., Suzuki, Masako, Stasiek, Edyta, ...
The distribution of cytosine methylation in 6.2 Mb of the mouse genome was tested using cohybridization of genomic representations from a methylation-sensitive restriction enzyme and its...
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Comparative isoschizomer profiling of cytosine methylation: The HELP assay (2006)
Khulan, Batbayar, Thompson, Reid F., Ye, Kenny, Fazzari, Melissa J., Suzuki, Masako, Stasiek, Edyta, ...
The distribution of cytosine methylation in 6.2 Mb of the mouse genome was tested using cohybridization of genomic representations from a methylation-sensitive restriction enzyme and its...
Selzer, Rebecca R., Nyaga, Simon, Tuo, Jingsheng, May, Alfred, Muftuoglu, Meltem, Christiansen, Mette, ...
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include...
Sunesen, Morten, Selzer, Rebecca R., Brosh Jr, Robert M., Balajee, Adayabalam S., Stevnsner, Tinna, Bohr, Vilhelm A.
Cockayne syndrome (CS) is a human genetic disorder characterized by post-natal growth failure, neurological abnormalities and premature aging. CS cells exhibit high sensitivity to UV light, delayed...
Selzer, Rebecca R., Elfarra, Adnan A.
We have previously shown that butadiene monoxide (BM), the primary metabolite of 1,3-butadiene, reacted with nucleosides to form alkylation products that exhibited different rates of formation and...
Brosh, Robert M., Balajee, Adayabalam S., Selzer, Rebecca R., Sunesen, Morten, De Santis, Luca Proietti, Bohr, Vilhelm A.
Cockayne syndrome (CS) is a human genetic disorder characterized by UV sensitivity, developmental abnormalities, and premature aging. Two of the genes involved, CSA and CSB, are required for...
Selzer, Rebecca R., Nyaga, Simon, Tuo, Jingsheng, May, Alfred, Muftuoglu, Meltem, Christiansen, Mette, ...
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include...
Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein
Sunesen, Morten, Selzer, Rebecca R., Brosh, Robert M., Balajee, Adayabalam S., Stevnsner, Tinna, Bohr, Vilhelm A.
Cockayne syndrome (CS) is a human genetic disorder characterized by post-natal growth failure, neurological abnormalities and premature aging. CS cells exhibit high sensitivity to UV light, delayed...
Brosh, Robert M., Balajee, Adayabalam S., Selzer, Rebecca R., Sunesen, Morten, De Santis, Luca Proietti, Bohr, Vilhelm A.
Cockayne syndrome (CS) is a human genetic disorder characterized by UV sensitivity, developmental abnormalities, and premature aging. Two of the genes involved, CSA and CSB, are required for...
Selzer, Rebecca R., Nyaga, Simon, Tuo, Jingsheng, May, Alfred, Muftuoglu, Meltem, Christiansen, Mette, ...
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include...
Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein
Sunesen, Morten, Selzer, Rebecca R., Brosh, Robert M., Balajee, Adayabalam S., Stevnsner, Tinna, Bohr, Vilhelm A.
Cockayne syndrome (CS) is a human genetic disorder characterized by post-natal growth failure, neurological abnormalities and premature aging. CS cells exhibit high sensitivity to UV light, delayed...
A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome
Graubert, Timothy A, Cahan, Patrick, Edwin, Deepa, Selzer, Rebecca R, Richmond, Todd A, Eis, Peggy S, ...
Submicroscopic (less than 2 Mb) segmental DNA copy number changes are a recently recognized source of genetic variability between individuals. The biological consequences of copy number variants...
Comparative isoschizomer profiling of cytosine methylation: The HELP assay
Khulan, Batbayar, Thompson, Reid F., Ye, Kenny, Fazzari, Melissa J., Suzuki, Masako, Stasiek, Edyta, ...
The distribution of cytosine methylation in 6.2 Mb of the mouse genome was tested using cohybridization of genomic representations from a methylation-sensitive restriction enzyme and its...
Dostie, Josée, Richmond, Todd A., Arnaout, Ramy A., Selzer, Rebecca R., Lee, William L., Honan, Tracey A., ...
Physical interactions between genetic elements located throughout the genome play important roles in gene regulation and can be identified with the Chromosome Conformation Capture (3C) methodology....
Maydan, Jason S., Flibotte, Stephane, Edgley, Mark L., Lau, Joanne, Selzer, Rebecca R., Richmond, Todd A., ...
We have developed array Comparative Genomic Hybridization for Caenorhabditis elegans as a means of screening for novel induced deletions in this organism. We designed three microarrays consisting of...
An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation
Figueroa, Maria E., Reimers, Mark, Thompson, Reid F., Ye, Kenny, Li, Yushan, Selzer, Rebecca R., ...
The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation...
Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...
Oda, Mayumi, Glass, Jacob L., Thompson, Reid F., Mo, Yongkai, Olivier, Emmanuel N., Figueroa, Maria E., ...
Many genome-wide assays involve the generation of a subset (or representation) of the genome following restriction enzyme digestion. The use of enzymes sensitive to cytosine methylation allows...
Acquired copy number alterations in adult acute myeloid leukemia genomes
Walter, Matthew J., Payton, Jacqueline E., Ries, Rhonda E., Shannon, William D., Deshmukh, Hrishikesh, Zhao, Yu, ...
Cytogenetic analysis of acute myeloid leukemia (AML) cells has accelerated the identification of genes important for AML pathogenesis. To complement cytogenetic studies and to identify genes altered...