Reinhard Engels

Publication List Details

Period

2006 - 2009

Number

13

Co-Authors

TB database: an integrated platform for tuberculosis research (2009)

Reddy, T. B. K., Riley, Robert, Wymore, Farrell, Montgomery, Phillip, DeCaprio, Dave, Engels, Reinhard, ...

The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of...

BIOINFORMATICS APPLICATIONS NOTE Genome analysis Combo: a whole genome comparative browser (2008)

Reinhard Engels, Tamara Yu, Chris Burge, Jill P. Mesirov, David Decaprio, James E. Galagan

Summary: Combo is a comparative genome browser that provides a dynamic view of whole genome alignments along with their associated annotations. Combo provides two different visualization...

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis (2006)

Yu, Yiting, Kim, H Stanley, Chua, Hui, Lin, Chi, Sim, Siew, Lin, Daoxun, ...

Abstract Background The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp...

Genomic Patterns of Pathogen Evolution Revealed by Comparison of Burkholderia pseudomallei, the Causative Agent of Melioidosis, to Avirulent Burkholderia thailandensis (2006)

Yu, Yiting, Kim, H. S., Chua, Hui H., Lin, Chi H., Sim, Siew H., Lin, Daoxun, ...

The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we...

Combo: a whole genome comparative browser (2006)

Engels, Reinhard, Yu, Tamara, Burge, Chris, Mesirov, Jill P., DeCaprio, David, Galagan, James E.

Summary: Combo is a comparative genome browser that provides a dynamic view of whole genome alignments along with their associated annotations. Combo provides two different visualization...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

The Genome of M. acetivorans Reveals Extensive Metabolic and Physiological Diversity

Galagan, James E., Nusbaum, Chad, Roy, Alice, Endrizzi, Matthew G., Macdonald, Pendexter, FitzHugh, Will, ...

Methanogenesis, the biological production of methane, plays a pivotal role in the global carbon cycle and contributes significantly to global warming. The majority of methane in nature is derived...

Dynamics of Pseudomonas aeruginosa genome evolution

Mathee, Kalai, Narasimhan, Giri, Valdes, Camilo, Qiu, Xiaoyun, Matewish, Jody M., Koehrsen, Michael, ...

One of the hallmarks of the Gram-negative bacterium Pseudomonas aeruginosa is its ability to thrive in diverse environments that includes humans with a variety of debilitating diseases or immune...

TB database: an integrated platform for tuberculosis research

Reddy, T. B. K., Riley, Robert, Wymore, Farrell, Montgomery, Phillip, DeCaprio, Dave, Engels, Reinhard, ...

The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of...

Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies

Champion, Mia D., Zeng, Qiandong, Nix, Eli B., Nano, Francis E., Keim, Paul, Kodira, Chinnappa D., ...

Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis. In order to...

Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication

Ma, Li-Jun, Ibrahim, Ashraf S., Skory, Christopher, Grabherr, Manfred G., Burger, Gertraud, Butler, Margi, ...

Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with an overall mortality rate that exceeds 50%. As a...