Reinhard K. Straubinger

Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis (2009)

Siegemund, Sabine, Schütze, Nicole, Schulz, Silke, Wolk, Kerstin, Nasilowska, Katarzyna, Straubinger, Reinhard K., ...

Early activation of the IL-12/IFN-γ axis has been shown following Salmonella enterica serovar Enteritidis (S. Enteritidis) infection. We were interested to study whether IL-22 and IL-17A production...

IL-12 family members: differential kinetics of their TLR4-mediated induction by Salmonella Enteritidis and the impact of IL-10 in bone marrow-derived macrophages (2005)

Schuetze, Nicole, Schoeneberger, Sabine, Mueller, Uwe, Freudenberg, Marina A., Alber, Gottfried, Straubinger, Reinhard K.

The members of the IL-12 family of heterodimeric cytokines play a pivotal role in initiation and regulation of cell-mediated immunity. Best known is IL-12p70, which promotes an immune response...

IL-12 family members: differential kinetics of their TLR4-mediated induction by Salmonella Enteritidis and the impact of IL-10 in bone marrow-derived macrophages (2005)

Schuetze, Nicole, Schoeneberger, Sabine, Mueller, Uwe, Freudenberg, Marina A., Alber, Gottfried, Straubinger, Reinhard K.

The members of the IL-12 family of heterodimeric cytokines play a pivotal role in initiation and regulation of cell-mediated immunity. Best known is IL-12p70, which promotes an immune response...

PCR-Based Quantification of Borrelia burgdorferi Organisms in Canine Tissues over a 500-Day Postinfection Period

Straubinger, Reinhard K.

Borrelia burgdorferi infection in beagle dogs was studied quantitatively with skin punch biopsy samples and blood samples collected at 4- and 2-week intervals, respectively, over a 500-day period....

Characterization of a Borrelia burgdorferi VlsE Invariable Region Useful in Canine Lyme Disease Serodiagnosis by Enzyme-Linked Immunosorbent Assay

Liang, Fang Ting, Jacobson, Richard H., Straubinger, Reinhard K., Grooters, Amy, Philipp, Mario T.

Sera collected from dogs experimentally infected with Borrelia burgdorferi by tick inoculation were analyzed for an antibody response to each of the six invariable regions (IRs; i.e., IR1 to IR6) of...

Helicobacter felis Infection Is Associated with Lymphoid Follicular Hyperplasia and Mild Gastritis but Normal Gastric Secretory Function in Cats

Simpson, Kenneth W., Strauss-Ayali, Dalit, Scanziani, Eugenio, Straubinger, Reinhard K., McDonough, Patrick L., Straubinger, Alix F., ...

The relationship of Helicobacter felis, a bacterium observed in the stomachs of cats, to gastric disease is unclear. The objective of this study was to determine if H. felis infection alters gastric...

Borrelia burgdorferi Induces the Production and Release of Proinflammatory Cytokines in Canine Synovial Explant Cultures

Straubinger, Reinhard K., Straubinger, Alix F., Summers, Brian A., Erb, Hollis N., Härter, Luc, Appel, Max J. G.

Canine synovial membrane explants were exposed to high- or low-passage Borrelia burgdorferi for 3, 6, 12, and 24 h. Spirochetes received no treatment, were UV light irradiated for 16 h, or were...

Quantitative Evaluation of Inflammatory and Immune Responses in the Early Stages of Chronic Helicobacter pylori Infection

Straubinger, Reinhard K., Greiter, Andrea, McDonough, Sean P., Gerold, Alexander, Scanziani, Eugenio, Soldati, Sabina, ...

The early consequences of Helicobacter pylori infection and the role of bacterial virulence determinants in disease outcome remain to be established. The present study sought to measure the...

Borrelia burgdorferi Organisms Lacking Plasmids 25 and 28-1 Are Internalized by Human Blood Phagocytes at a Rate Identical to That of the Wild-Type Strain

Al-Robaiy, Samiya, Knauer, Jens, Straubinger, Reinhard K.

Lyme borreliosis caused by Borrelia burgdorferi is a persistent infection capable of withstanding the host's vigorous immune response. Several reports have shown that the spirochete's linear plasmids...

PCR-Based Quantification of Borrelia burgdorferi Organisms in Canine Tissues over a 500-Day Postinfection Period

Straubinger, Reinhard K.

Borrelia burgdorferi infection in beagle dogs was studied quantitatively with skin punch biopsy samples and blood samples collected at 4- and 2-week intervals, respectively, over a 500-day period....

Characterization of a Borrelia burgdorferi VlsE Invariable Region Useful in Canine Lyme Disease Serodiagnosis by Enzyme-Linked Immunosorbent Assay

Liang, Fang Ting, Jacobson, Richard H., Straubinger, Reinhard K., Grooters, Amy, Philipp, Mario T.

Sera collected from dogs experimentally infected with Borrelia burgdorferi by tick inoculation were analyzed for an antibody response to each of the six invariable regions (IRs; i.e., IR1 to IR6) of...

Helicobacter felis Infection Is Associated with Lymphoid Follicular Hyperplasia and Mild Gastritis but Normal Gastric Secretory Function in Cats

Simpson, Kenneth W., Strauss-Ayali, Dalit, Scanziani, Eugenio, Straubinger, Reinhard K., McDonough, Patrick L., Straubinger, Alix F., ...

The relationship of Helicobacter felis, a bacterium observed in the stomachs of cats, to gastric disease is unclear. The objective of this study was to determine if H. felis infection alters gastric...

Borrelia burgdorferi Induces the Production and Release of Proinflammatory Cytokines in Canine Synovial Explant Cultures

Straubinger, Reinhard K., Straubinger, Alix F., Summers, Brian A., Erb, Hollis N., Härter, Luc, Appel, Max J. G.

Canine synovial membrane explants were exposed to high- or low-passage Borrelia burgdorferi for 3, 6, 12, and 24 h. Spirochetes received no treatment, were UV light irradiated for 16 h, or were...

Quantitative Evaluation of Inflammatory and Immune Responses in the Early Stages of Chronic Helicobacter pylori Infection

Straubinger, Reinhard K., Greiter, Andrea, McDonough, Sean P., Gerold, Alexander, Scanziani, Eugenio, Soldati, Sabina, ...

The early consequences of Helicobacter pylori infection and the role of bacterial virulence determinants in disease outcome remain to be established. The present study sought to measure the...

Borrelia burgdorferi Organisms Lacking Plasmids 25 and 28-1 Are Internalized by Human Blood Phagocytes at a Rate Identical to That of the Wild-Type Strain

Al-Robaiy, Samiya, Knauer, Jens, Straubinger, Reinhard K.

Lyme borreliosis caused by Borrelia burgdorferi is a persistent infection capable of withstanding the host's vigorous immune response. Several reports have shown that the spirochete's linear plasmids...