Renata Zobalova

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

Daxx inhibits stress-induced apoptosis in cardiac myocytes (2008)

Zobalova, Renata, Cowie, Emma Angela, Chladova, Jaromira, Dong, Lan-feng, Neuzil, Jiri

The role of the death-associated protein Daxx in modulation of apoptosis induced in cardiac myocytes by oxidative stress was studied. Exposure of cultured cardiomyocyte-like cells to oxidative stress...

Daxx inhibits stress-induced apoptosis in cardiac myocytes (2008)

Zobalova, Renata, Cowie, Emma Angela, Chladova, Jaromira, Dong, Lan-feng, Neuzil, Jiri

The role of the death-associated protein Daxx in modulation of apoptosis induced in cardiac myocytes by oxidative stress was studied. Exposure of cultured cardiomyocyte-like cells to oxidative stress...

A peptide conjugate of Vitamin E succinate targets breast cancer cells with high erbB2 expression (2007)

Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...

Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

A peptide conjugate of Vitamin E succinate targets breast cancer cells with high erbB2 expression (2007)

Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...

Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Mitochondria transmit apoptosis signalling in cardiomyocyte-like cells and isolated hearts exposed to experimental ischemia-reperfusion injury (2007)

Neuzil, Jiri, Widen, Cecilia, Gellert, Nina, Cowie, Emma Angela, Zobalova, Renata, Dong, Lan-feng, ...

Ischemia-reperfusion (I/R) is a condition leading to serious complications due to death of cardiac myocytes. We used the cardiomyocyte-like cell line H9c2 to study the mechanism underlying cell...

A peptide conjugate of Vitamin E succinate targets breast cancer cells with high erbB2 expression (2007)

Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...

Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...

Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)

Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...

Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...