Jin, Chunsheng, Altmann, Friedrich, Strasser, Richard, Mach, Lukas, Schähs, Matthias, Kunert, Renate, ...
A common argument against using plants as a production system for therapeutic proteins is their inability to perform authentic N-glycosylation. A major concern is the presence of beta 1,2-xylose and...
Hinterkörner, Georg, Brugger, Gudrun, Müller, Dethardt, Hesse, Friedemann, Kunert, Renate, Katinger, Hermann, ...
No abstract available.
Wolbank, Susanne, Kunert, Renate, Stiegler, Gabriela, Katinger, Hermann
We have previously generated human monoclonal anti-human immunodeficiency virus type 1 (anti-HIV-1) antibodies 2F5IgG and 2G12IgG with an exceptional cross-clade neutralizing potential. 2F5IgG and...
Zwick, Michael B., Komori, H. Kiyomi, Stanfield, Robyn L., Church, Sarah, Wang, Meng, ...
The human monoclonal antibody 2F5 neutralizes primary human immunodeficiency virus type 1 (HIV-1) with rare breadth and potency. A crystal structure of a complex of 2F5 and a peptide corresponding to...
Inhibition of Human Immunodeficiency Virus Type 1 Entry in Cells Expressing gp41-Derived Peptides
Egelhofer, Marc, Brandenburg, Gunda, Martinius, Holger, Schult-Dietrich, Patricia, Melikyan, Gregory, Kunert, Renate, ...
As the limitations of antiretroviral drug therapy, such as toxicity and resistance, become evident, interest in alternative therapeutic approaches for human immunodeficiency virus (HIV) infection is...
De Rosny, Eve, Vassell, Russell, Jiang, Shibo, Kunert, Renate, Weiss, Carol D.
We investigated how the broadly neutralizing monoclonal antibody 2F5 affects the human immunodeficiency virus type 1 envelope glycoprotein as it undergoes receptor-induced conformational changes and...
Binley, James M., Wrin, Terri, Korber, Bette, Zwick, Michael B., Wang, Meng, Chappey, Colombe, ...
Broadly neutralizing monoclonal antibodies (MAbs) are potentially important tools in human immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been intensively studied, but we...
Zwick, Michael B., Jensen, Richard, Church, Sarah, Wang, Meng, Stiegler, Gabriela, Kunert, Renate, ...
The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two broadly neutralizing human monoclonal antibodies, 2F5 and 4E10, and is an...
Wolbank, Susanne, Kunert, Renate, Stiegler, Gabriela, Katinger, Hermann
We have previously generated human monoclonal anti-human immunodeficiency virus type 1 (anti-HIV-1) antibodies 2F5IgG and 2G12IgG with an exceptional cross-clade neutralizing potential. 2F5IgG and...
Zwick, Michael B., Komori, H. Kiyomi, Stanfield, Robyn L., Church, Sarah, Wang, Meng, ...
The human monoclonal antibody 2F5 neutralizes primary human immunodeficiency virus type 1 (HIV-1) with rare breadth and potency. A crystal structure of a complex of 2F5 and a peptide corresponding to...
Inhibition of Human Immunodeficiency Virus Type 1 Entry in Cells Expressing gp41-Derived Peptides
Egelhofer, Marc, Brandenburg, Gunda, Martinius, Holger, Schult-Dietrich, Patricia, Melikyan, Gregory, Kunert, Renate, ...
As the limitations of antiretroviral drug therapy, such as toxicity and resistance, become evident, interest in alternative therapeutic approaches for human immunodeficiency virus (HIV) infection is...
De Rosny, Eve, Vassell, Russell, Jiang, Shibo, Kunert, Renate, Weiss, Carol D.
We investigated how the broadly neutralizing monoclonal antibody 2F5 affects the human immunodeficiency virus type 1 envelope glycoprotein as it undergoes receptor-induced conformational changes and...
Binley, James M., Wrin, Terri, Korber, Bette, Zwick, Michael B., Wang, Meng, Chappey, Colombe, ...
Broadly neutralizing monoclonal antibodies (MAbs) are potentially important tools in human immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been intensively studied, but we...
Zwick, Michael B., Jensen, Richard, Church, Sarah, Wang, Meng, Stiegler, Gabriela, Kunert, Renate, ...
The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two broadly neutralizing human monoclonal antibodies, 2F5 and 4E10, and is an...
Hinterkörner, Georg, Brugger, Gudrun, Müller, Dethardt, Hesse, Friedemann, Kunert, Renate, Katinger, Hermann, ...
Serum-free transfection of CHO-cells with tailor-made unilamellar vesicles
Reisinger, Hannes, Sevcsik, Eva, Vorauer-Uhl, Karola, Lohner, Karl, Katinger, Hermann, Kunert, Renate
At present, a number of transfection techniques are available to introduce foreign DNA into cells, but still minimal intrusion or interference with normal cell physiology, low toxicity,...
Huarte, Nerea, Lorizate, Maier, Maeso, Rubén, Kunert, Renate, Arranz, Rocio, Valpuesta, José M., ...
The broadly neutralizing 2F5 and 4E10 monoclonal antibodies (MAbs) recognize epitopes within the membrane-proximal external region (MPER) that connects the human immunodeficiency virus type 1 (HIV-1)...