Velho, Sérgia, Moutinho, Cátia, Cirnes, Luís, Albuquerque, Cristina, Hamelin, Richard, Schmitt, Fernando, ...
Abstract Background BRAF , KRAS and PIK3CA mutations are frequently found in sporadic colorectal cancer (CRC). In contrast to KRAS and PIK3CA mutations, BRAF mutations are associated with tumours...
Wong, Yick Fu, Cheung, Tak Hong, Lo, Keith Wing Kit, Yim, So Fan, Chan, Loucia Kit Yin, Buhard, Olivier, ...
The aim of this study was to find the optimal set of microsatellite markers for diagnosis of the microsatellite instability (MSI) phenotype in endometrial cancers. We compared the sensitivity,...
Wong, Yick Fu, Cheung, Tak Hong, Kit Lo, Keith Wing, Yim, So Fan, Chan, Loucia Kit Yin, Buhard, Olivier, ...
The aim of this study was to find the optimal set of microsatellite markers for diagnosis of the microsatellite instability (MSI) phenotype in endometrial cancers. We compared the sensitivity,...
Bchiri, Jamila El, Buhard, Olivier, Penard-Lacronique, Virginie, Thomas, Gilles, Hamelin, Richard, Duval, Alex
The Nonsense Mediated Decay (NMD) system normally targets mRNAs with premature termination codons (PTC) for rapid degradation. We investigated for a putative role of NMD in cancers with...
El-Bchiri, Jamila, Buhard, Olivier, Penard-Lacronique, Virginie, Thomas, Gilles, Hamelin, Richard, Duval, Alex
The nonsense-mediated decay (NMD) system normally targets mRNAs with premature termination codons (PTCs) for rapid degradation. We investigated for a putative role of NMD in cancers with...
Lind, Guro E, Thorstensen, Lin, Løvig, Tone, Meling, Gunn I, Hamelin, Richard, Rognum, Torleiv O, ...
Abstract Background Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable...
Lind, Guro, Thorstensen, Lin, Løvig, Tone, Meling, Gunn, Hamelin, Richard, Rognum, Torleiv, ...
BACKGROUND: Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9...
The mutator pathway is a feature of immunodeficiency-related lymphomas (2004)
Duval, Alex, Raphael, Martine, Brennetot, Caroline, Poirel, Helene, Buhard, Olivier, Aubry, Alban, ...
The mutator phenotype caused by defects in the mismatch repair system is observed in a subset of solid neoplasms characterized by widespread microsatellite instability-high (MSI-H). It is known to be...
Lind, Guro, Thorstensen, Lin, Løvig, Tone, Meling, Gunn, Hamelin, Richard, Rognum, Torleiv, ...
BACKGROUND: Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9...
Lind, Guro, Thorstensen, Lin, Løvig, Tone, Meling, Gunn, Hamelin, Richard, Rognum, Torleiv, ...
BACKGROUND: Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9...
Lind, Guro, Thorstensen, Lin, Løvig, Tone, Meling, Gunn, Hamelin, Richard, Rognum, Torleiv, ...
BACKGROUND: Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9...
Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...
Oliveira, Carla, Westra, Jantine L., Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from hereditary non-polyposis colorectal cancer...
Umar, Asad, Boland, C. Richard, Terdiman, Jonathan P., Syngal, Sapna, Chapelle, Albert De La, Rüschoff, Josef, ...
Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a common autosomal dominant syndrome characterized by early age at onset, neoplastic lesions, and microsatellite...
Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...
Duval, Alex, Rolland, Sandra, Compoint, Aurore, Tubacher, Emmanuel, Iacopetta, Barry, Thomas, Gilles, ...
A number of human genes containing coding mononucleotide repeat sequences are particularly prone to mutations in tumors with defects in mismatch repair (MMR) genes (MSI-H cancers). In a large series...
Alternative genetic pathways in colorectal carcinogenesis
Olschwang, Sylviane, Hamelin, Richard, Laurent-Puig, Pierre, Thuille, Bénédicte, De Rycke, Yann, Li, You-Jun, ...
The comparative typing of matched tumor and blood DNAs at dinucleotide repeat (microsatellite) loci has revealed in tumor DNA the presence of alleles that are not observed in normal DNA. The...
The mutator pathway is a feature of immunodeficiency-related lymphomas
Duval, Alex, Raphael, Martine, Brennetot, Caroline, Poirel, Helene, Buhard, Olivier, Aubry, Alban, ...
The mutator phenotype caused by defects in the mismatch repair system is observed in a subset of solid neoplasms characterized by widespread microsatellite instability-high (MSI-H). It is known to be...
A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
Lind, Guro E, Thorstensen, Lin, Løvig, Tone, Meling, Gunn I, Hamelin, Richard, Rognum, Torleiv O, ...
Alternative genetic pathways in colorectal carcinogenesis
Olschwang, Sylviane, Hamelin, Richard, Laurent-Puig, Pierre, Thuille, Bénédicte, De Rycke, Yann, Li, You-Jun, ...
The comparative typing of matched tumor and blood DNAs at dinucleotide repeat (microsatellite) loci has revealed in tumor DNA the presence of alleles that are not observed in normal DNA. The...
The mutator pathway is a feature of immunodeficiency-related lymphomas
Duval, Alex, Raphael, Martine, Brennetot, Caroline, Poirel, Helene, Buhard, Olivier, Aubry, Alban, ...
The mutator phenotype caused by defects in the mismatch repair system is observed in a subset of solid neoplasms characterized by widespread microsatellite instability-high (MSI-H). It is known to be...
A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
Lind, Guro E, Thorstensen, Lin, Løvig, Tone, Meling, Gunn I, Hamelin, Richard, Rognum, Torleiv O, ...
Chromosomal Instability in Near-Diploid Colorectal Cancer: A Link between Numbers and Structure
Muleris, Martine, Chalastanis, Alexandra, Meyer, Nicolas, Lae, Marick, Dutrillaux, Bernard, Sastre-Garau, Xavier, ...
Chromosomal instability (CIN) plays a crucial role in tumor development and occurs mainly as the consequence of either missegregation of normal chromosomes (MSG) or structural rearrangement (SR)....